Frag' FlorenceEvidenz. Klar. Anwendbar.
Uhr 7/8Sources Journal Tree
Easy Demo

Florence Themenbrowser · Alter & Demenz · Seite 116

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
04.08.2026journal-article

Frontiers in Public Health

Participation in physical activity and life skills in older adults: sequential roles of resilience and ego integrity

Hyojung Kwon, Inwoo Kim

Background As the global population ages, fostering adaptive capacities to resolve daily challenges has become a critical public health priority. While older adults’ participation in physical activity is known to promote healthy aging, the psychological processes through which it may be associated with practical life skills in older adults remain under-explored. Objective This study investigated the sequential associations between participation in physical activity and life skills in older adults, focusing on the r …

05.08.2026journal-article

The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences

Longitudinal trajectories of social frailty and the risk of all-cause mortality among older adults in South Korea: exploration of the mediating role of cognitive functioning

Seong-Uk Baek, Jin-Ha Yoon

Abstract Background Mounting evidence indicates that social frailty leads to adverse health outcomes in older adults. However, longitudinal trajectories of social frailty and their relationship with all-cause mortality have not been fully investigated. We analyzed the association between social frailty trajectories and all-cause mortality, and the mediating role of cognitive functioning in this relationship. Methods A nationally representative sample of older adults in South Korea was analyzed (n = 5941). Social fr …

04.08.2026journal-article

Journal of the American Geriatrics Society

A Personalized, Symptom‐Based Approach to Boost Research Participation in Hospitalized Older Adults

Nicole Ceriani, Shreya Dhar, Catherine Zhao, Ian Sherrington, Eyal Y. Kimchi

ABSTRACT Background Delirium is common among hospitalized older adults on many clinical services and associated with poor outcomes. Given delirium's fluctuations, wearable devices are promising continuous monitors. While recruiting for a wearable electroencephalography (EEG) delirium study, we initially experienced low enrollment rates among older adults and patients on non‐neurologic services. Our aim was to understand patient and community perspectives on inpatient, wearable research to adapt recruitment protocol …

04.08.2026journal-article

Cerrahpaşa Medical Journal

Population Aging, Obesity, and Regional Disparities in Osteoarthritis Prevalence Across World Health Organization Regions: A Panel Data Study

Muhammed Yusuf Afacan, Mete Özer, Arın Celayir, Baran Suat Sevgil, Onur Yıldırım, Önder Aydıngöz, Hüseyin Botanlıoğlu, Serdar Kuzu

Objective: Although previous studies have examined the relationship between osteoarthritis (OA), aging, and obesity in selected settings, evidence at the level of World Health Organization (WHO) regions remains limited. The aim was to assess regional disparities and temporal trends in OA prevalence across WHO regions and its association with population aging and obesity. Methods: This longitudinal ecological panel study included 6 WHO regions from 2000 to 2016, with region-year as the unit of analysis (102 observat …

04.08.2026journal-article

Dendrobiology

Edible mushrooms gathered by the Asháninka people in Peruvian Amazonia: the dominance of lignicolous taxa

­Monika Kujawska, Łukasz Łuczaj, Małgorzata Karbarz

Information on edible mushrooms among the indigenous societies of South America’s lowlands is scarce. Recent studies suggest that indigenous Amazonian groups exhibit a spectrum ranging from intense mycophobia to mild mycophilia. The Asháninka people, who belong to the Arawak language family, are the largest group in the Peruvian Amazonia. They have inhabited the tributaries of the Ucayali River for centuries, mainly dedicating themselves to horticulture and fishing, with a lesser emphasis on foraging. This is the f …

04.08.2026journal-article

Energies

Non-Uniform Aging Diagnosis of High-Voltage Machine Stator-Winding Insulation Using Multi-Indicator Fusion of Dielectric Spectra

Zongbao Gao, Guoqiang Gao, Dong Yang, Jing Zhang

Accurate assessment of the stator-winding insulation condition in high-voltage machines is crucial for safe operation. Conventional evaluation methods treat the insulation as spatially uniform and provide only a holistic assessment; in practice, however, degradation within the insulation wall is non-uniform, with the inner layers adjacent to the copper conductor typically deteriorating more severely. As a result, existing diagnostic approaches cannot accurately evaluate non-uniform degradation. To address this gap, …

04.08.2026journal-article

Frontiers in Aging Neuroscience

Microglia–astrocyte crosstalk as a key organizing principle of Alzheimer’s disease: from homeostatic cooperation to maladaptive signaling loops

Mingqiang Gong, Jiao Lan, Jifei Miao

Alzheimer’s disease (AD) has long been framed around amyloid-beta (Aβ) and tau pathology, yet mounting evidence indicates that dysfunctional microglia–astrocyte crosstalk is an important, and often underappreciated, contributor to disease progression that operates alongside—rather than in place of—neuronal, vascular, and proteinopathic mechanisms. Here we propose a three-stage framework in which glial communication transitions from silent vulnerability through organized defense to maladaptive collapse. During precl …

04.08.2026journal-article

JSSIT: Jurnal Sains dan Sains Terapan

Uji Antioksidan Ekstrak Daun Pegagan (Centella Asiatica) sebagai Kandidat Anti Aging Menggunakan Metode 2,2-Difenil -1- Pikrilhidrazil

Nursinta

Paparan sinar matahari berlebih dapat menyebabkan penuaan dini dan kerusakan kulit akibat radikal bebas. Untuk mengatasi hal ini diperlukan antioksidan alami yang aman dan efektif. Penelitian ini mengkaji aktivitas antioksidan ekstrak daun pegagan (Centella asiatica) sebagai kandidat bahan aktif anti-aging. Untuk sumber antioksidan alami pengganti senyawa sintetik yang berpotensi toksik. Pada penelitian bertujuan untuk menentukan senyawa bioaktif yang terkandung dalam daun pegagan serta mengetahui aktivitas antioks …

04.08.2026journal-article

Journal of Clinical Medicine

Machine Learning Classification of Current Functional Impairment in Older Adults with Diabetes: Evidence from CHARLS 2015

Qi-Shuai Ma, Li-Qun Jiang, Buong-O Chun

Background: Functional impairment is common among older adults with diabetes, but multidimensional machine learning classification in this population remains underexplored. This study compared machine learning algorithms for identifying concurrent functional impairment among older adults with self-reported physician-diagnosed diabetes. Methods: This cross-sectional study included 1213 adults aged ≥ 65 years from the nationally sampled 2015 China Health and Retirement Longitudinal Study cohort. Functional impairment …

04.08.2026journal-article

Frontiers in Endocrinology

Artificial intelligence in osteoporosis screening and fracture risk prediction among aging populations: a bibliometric evidence map

Bo Wang, Sijin Tang, Pingjuan Tan, Baohong Mi, Weiheng Chen, Chunzhu Gong, Renxuan Yang, Qiushi Wei

Objective To map the development, knowledge structure, and clinical translation of artificial intelligence applications in osteoporosis screening and fracture risk prediction among aging populations, with a focus on risk stratification, prediction-oriented modeling, and endocrine bone health management. Methods A bibliometric evidence-mapping study was conducted using publications retrieved from the Web of Science Core Collection and PubMed. VOSviewer and R/bibliometrix were used to analyze publication and citation …

04.08.2026journal-article

Frontiers in Conservation Science

Amazonian community-based conservation catalyzes multidimensional nature contributions to people

Ana Carla Rodrigues, Eduardo Sonnewend Brondizio, Hugo Cardoso de Moura Costa, Carlos Augusto Peres, Richard James Ladle, Ana Claudia Mendes Malhado, José Antonio Puppim de Oliveira, Fabio do Carmo Gondim, João Vitor Campos-Silva

The Amazon rainforest hosts a remarkable level of biodiversity which, in turn, generates diverse and significant ecosystem services for humanity. Conserving the vast territories of the Amazon requires the active participation of the many traditional indigenous and non-indigenous communities that inhabit the region. For example, the conservation of the giant pirarucu fish through co-management with local Amazonian communities has objectively delivered successful conservation and social outcomes. Here, we identify th …

04.08.2026journal-article

Frontiers in Rehabilitation Sciences

Identifying the experiences, challenges and opportunities along pathways for community-based digital skill development for young people with disabilities in Canada: a community-based research study

Alana Armas, Charlotte Buttle, Erica Johnston, Gabriella Avila Patro, Bliss Reynolds, Hedgerow Thompson, Darian Karuza, Ayodeji Olaomi, Kristen Rhodes

Introduction Young people with disabilities are disadvantaged in learning and developing the skills they need to gain successful and sustained employment in Canada. This includes the development of digital skills, which are increasingly essential to participate in many aspects of society. The purpose of this study was to explore how young people with disabilities develop their digital skills outside of school. Methods Using a community-based research approach the study specifically aimed to: 1) identify the challen …

04.08.2026journal-article

PLANTS, PEOPLE, PLANET

The need for manual curation of the cotton proteome leads to a solution primed for undergraduate involvement

Jonathan Zirkel, Amanda R. Storm, Grant T. Billings, Amanda M. Hulse‐Kemp

Societal Impact Statement Cotton is a global crop cultivated worldwide, yet a significant portion of the cotton genome remains functionally unannotated. Attempts have been made to automate this annotation but have been unable to completely bridge the gap. Human curation is still needed for accurate interpretations and predictions to be made. We present a solution leveraging a course‐based approach to annotating protein function in a format tailored for undergraduate students. This format produces significant insigh …

04.08.2026journal-article

ASCE MAGAZINE

Comprehensive Telemedicine for Complex Geriatric Patients: An AI-Based Care Model for the Early Detection of Gastrointestinal and Nephrological Decompensations

Mario Daniel Hidalgo Flores, Mishell Esperanza Atiencia Tibanta, Ana Lucía Alarcón Arias, María Paula Salgado Acosta, Ana Maria Burneo Feijoo

Artificial intelligence (AI)-enhanced telemedicine is emerging as a promising approach for managing complex geriatric patients, a group at high risk for decompensations. However, the intellectual structure and evolutionary trends of this specific research area remain unclear. To conduct a bibliometric analysis to map the scientific landscape on the application of AI and telemedicine for the early detection of gastrointestinal and nephrological decompensations in complex geriatric patients. A systematic bibliometric …

04.08.2026journal-article

Journal of Clinical Nursing

The Impact of Social Participation Interventions on Quality of Life of Older Adults in Residential Aged Care Facilities: A Systematic Review

Sara Habibian, Guogui Huang, Nasir Wabe, Johanna I. Westbrook, Amy D. Nguyen

ABSTRACT Aim To examine the impact of social participation interventions on the quality of life of older adults in residential aged care home settings. Design Systematic review. Methods The inclusion criteria were articles published in English language between 2015 and 2025, peer‐reviewed articles, availability of full‐text, and conducted in residential aged care home settings, aged 65 years and over. Quality appraisal of articles was conducted using the Mixed Methods Appraisal Tool. Data Sources A systematic searc …

04.08.2026journal-article

JNCI: Journal of the National Cancer Institute

The joint association of clonal hematopoiesis of indeterminate potential and biological aging with cancer risk among 332,911 individuals

Li Wang, Kaili Sun, Siqi Lu, Yuyang Zheng, Xueqing Jia, Yanjie Zhao, Lujia Shen, Jingyun Zhang, Jing Shao, Xiao Tan, Jie Sun, Zuyun Liu

Abstract Background Clonal hematopoiesis of indeterminate potential (CHIP) and biological aging have been individually associated with increased cancer risks. However, their joint effect on cancer risks remains unknown. Methods We analyzed data from 332,911 participants at baseline in the UK Biobank. We defined CHIP as a pathogenic variant with variant allele fractions ≥2%. Biological aging was assessed by the phenotypic age acceleration (PhenoAgeAccel) and categorized as biologically younger and older. Association …

04.08.2026journal-article

Moscow State University of Technology and Management named after K.G. Razumovsky (First Cossack University). Social Sciences Series

ТРАДИЦИОННЫЕ ЦЕННОСТИ РУССКОГО МИРА И ИСТОРИОСОФСКАЯ СУЩНОСТЬ РУССКОЙ ИДЕИ КАК ГЛАВНЫЕ ПРИНЦИПЫ ФОРМИРОВАНИЯ НАЦИОНАЛЬНОЙ ИДЕНТИЧНОСТИ РУССКОГО НАРОДА В СОВРЕМЕННОСТИ. МАСС-МЕДИЙНЫЙ АСПЕКТ

Ю.В. Кот

Проведен культурологический анализ понятия «Русский мир» и историософской сущности русской идеи в контексте массового сознания, национальной идентичности с опорой на традицию русской философской мысли. Феномен русской идеи рассматривается как актуальное явление духовной жизни современной России. Для государственных и патриотически направленных частных масс-медиа, включая электронные, контекст понятия «Русский мир» и суть русской идеи являются приоритетными для трансляции широким массам населения России и союзническ …

04.08.2026journal-article

F1000Research

Comparative Effectiveness of Progressive Muscle Relaxation, Autogenic Training, and Combined Therapy on Blood Pressure Among Older Adults with Hypertension: A Quasi-Experimental Study

Puji Setya Rini, Santhna Letchmi Panduragan, Fatimah Yahya, Hafizah Che Hassan, Yulius Tiranda

Background Hypertension is a major chronic cardiovascular condition among older adults that contributes substantially to global morbidity and mortality rates. Mind–body therapies, such as progressive muscle relaxation (PMR) and autogenic training (AT), may help regulate blood pressure; however, evidence regarding their comparative and combined effects on institutionalized older adults is limited. This study evaluated the effects of PMR, AT, and combined PMR + AT interventions on blood pressure in older adults with …

04.08.2026journal-article

Frontiers in Public Health

Wuli-Shili-Renli methodology as a service quality management tool among private older adults care institutions in Taizhou, China: an empirical study

Lili Huang, Jing-Jing Fu, Dan Xu

Background Population aging, a global crisis, has made private integrated medical - nursing facilities the primary providers for older adults care. However, the operational flaws of these facilities can potentially be addressed by the China - originated Wuli-Shili-Renli (WSR) methodology, which integrates physical resources, systematic management, and human factors. Methods A retrospective empirical before-after study was conducted to evaluate the implementation effect of the WSR framework on service quality manage …

04.08.2026journal-article

SocietàMutamentoPolitica

«Two Heads Are Better Than One but They Must Be Good Ones»: Ethical and Methodological Challenges of Social Work With «people Living on the Street»

Andrea Gollini

This paper presents a case study analysis focused on an accompaniment process with a person living on the street, developed in a city in Northern Italy. Through the story of Arnold – a migrant man facing housing, employment, and relational precarity – the article examines key ethical and methodological challenges of social work with people who live on the street: managing relational timeframes, negotiating the boundaries between support and control, holding together protection and freedom, and the effort to sustain …

04.08.2026journal-article

Prosthetics & Orthotics International

Observational study of people with complete hand amputation using a multigrip myoelectric prosthesis after using a standard myoelectric prosthesis

Marc Marty, Nathalie de Hesselle, Mireille Grenier, Anthony Palacio, Michèle Timsit, Amelie Touillet, Frédéric Charlate, Stephane Vigier, Emilie Leblong, Yoann Ronzi, Léo Borrini, Emilie Braley, Patrice Schumacker, Simona Audemar, Thierry Jacob-Chia, Estelle Elie, Juliette Milcamps, Renaud Urbinelli, Isabelle Loiret

Background: Clinical evidence substantiating the advantages multi-grip myoelectric hand prosthesis over conventional myoelectric hand prosthesis in daily life remains inconclusive. Objectives: The study aimed to assess the efficacy of using a multi-grip myoelectric hand prosthesis after utilizing a conventional myoelectric hand prosthesis. Study Design: A before-and-after, multi-center, observational study included adults with complete hand amputation using a standard myoelectric hand prosthesis for more than 4 wee …

14.08.2026journal-article

Journal of Antimicrobial Chemotherapy

Do current oral ciprofloxacin regimens achieve pharmacokinetic/pharmacodynamic targets within safe exposure limits in older adults with Pseudomonas aeruginosa infection? A population pharmacokinetic analysis

Mehdi El Hassani, Daniel J G Thirion, Aysenur Yaliniz, Katherine Desforges, Josée Verdon, Emily G McDonald, Amélie Marsot

Abstract Background Ciprofloxacin is one of the few orally available antibiotics with activity against Pseudomonas aeruginosa. This study developed a population pharmacokinetic (popPK) model for oral ciprofloxacin in older adults and evaluated whether standard regimens achieve the pharmacokinetic/pharmacodynamic (PK/PD) target of 24 h area under the concentration–time curve over minimal inhibitory concentration (AUC0-24/MIC) ≥ 125. Methods This was a prospective pilot study in patients ≥75 years taking oral ciprofl …

14.08.2026journal-article

Journal of Antimicrobial Chemotherapy

Factors associated with virological failure in people with HIV treated with bictegravir/emtricitabine/tenofovir alafenamide. Impact of pre-existing mutations and risk of resistance emergence. ANRS-CO3-AquiVIH-NA cohort

Pantxika Bellecave, Alaric Peyrouny-Mazeau, Olivier Leleux, Mojgan Hessamfar, Gwenaël Le Moal, Didier Neau, Laure Alleman, Charles Cazanave, Estibaliz Lazaro, Pierre Duffau, Marie-Anne Vandenhende, Bernard Castan, Camille Tumiotto, Fabrice Bonnet

Abstract Objectives We investigated, in a real-world setting, virological factors associated with virological failure (VF) after bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) initiation in people with HIV (PWH) with and without pre-existing drug resistance mutation (PRM) and the emergence of new resistance mutations at virological failure. Methods Treatment-experienced PWH from ANRS-CO3-AquiVIH-NA cohort starting B/F/TAF between 2018 and 2021 were stratified depending on their baseline viral load (VL): …