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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
13.08.2026journal-article

Advanced Electromagnetics

Analysis on the Effect of Chinese Herbs Decoction Combined with Warm Acupuncture and Auricular Point Sticking Therapy on Insomnia Caused by Deficiency of Both Qi and Yin

L. Zhang, W. G. Xue, Y. Wang, H. X. Zhang, Y. Ma

Objective: This study investigates the therapeutic effect of Chinese herb decoction combined with warm acupuncture and auricular point sticking therapy on insomnia caused by deficiency of both Qi and Yin. Methods: A total of 104 patients with Qi-Yin deficiency-type insomnia admitted to the hospital from November 2023 to November 2024 are selected and randomly divided into Group A and Group B, with 52 cases in each group, using the random number table method. Group B receives routine Western medical treatment, while …

13.08.2026journal-article

Evidence-Based Dentistry

Chemically modified curcumin in periodontal therapy: a scoping review

Vishala Bhargavi Chilukuri, Rupali Agnihotri, Deepa G. Kamath

Abstract Aims/Objectives Periodontitis, a multifactorial chronic inflammatory disease that destroys the supporting structures of the teeth, is conventionally managed with treatments focusing on biofilm removal; however, these therapies do not fully address the dysregulated host response central to disease progression. To address this, chemically modified curcumin (CMC) analogues have been developed by modifying curcumin, a derivative of Curcuma longa , a host-modulating agent with potent anti-inflammatory and antio …

13.08.2026journal-article

Advanced Science

Kidney‐Targeted Cilastatin Nanoparticles Inhibit DPEP1‐Mediated Ferroptosis for Acute Kidney Injury Therapy

Wanbing Qin, Jiaqi Huang, Manting Zhang, Wanchun Yang, Mingwei Xu, Chi Jiang, Jiekai Li, Jinjuan Wen, Qibin Huang, Shiqi Wen, Weidong Wang, Junbing He, Qinghua Liu

ABSTRACT Cisplatin‐induced acute kidney injury (CI‐AKI) is a frequent, dose‐dependent complication in patients receiving cisplatin chemotherapy, and effective targeted treatments remain unavailable. The development of targeted therapies for CI‐AKI may improve the efficacy of chemotherapy while mitigating renal toxicity. Given that ferroptosis is a key pathological mechanism in CI‐AKI, targeted drug delivery systems against this process represent a promising therapeutic strategy. Dipeptidase 1 (DPEP1) is highly expr …

13.08.2026journal-article

Neurological Research and Practice

Guideline of the German Society of Neurology (DGN): "diagnosis and therapy of HIV-1-associated neurological disorders”

Katrin Hahn, Gabriele Arendt, Christian Eggers, Cristina Granziera, Matthias Maschke

Abstract Epidemiology and treatment of HIV changed substantially within the last three decades. However, HIV-associated neurological disorders such as mild forms of HIV-associated neurocognitive disorder (HAND) as well as HIV-associated distal symmetrical sensory polyneuropathy are amongst the most frequent complications in patients with longstanding HIV infection. Opportunistic infections occur less frequently compared to former years, but especially in patients with late presentation of HIV progressive multifocal …

13.08.2026journal-article

Stem Cells and Development

The Potential Role of Mesenchymal Stem Cell Therapy for Moderate-to-Severe Atopic Dermatitis: A Systematic Review and Meta-Analysis of Human Clinical Trials

Martin Cevallos-Cueva, Laura Ghanem, Taissa Novis, Sakshi Arora, Najwaa Kirmani, Sümeyye Aktaş, Esteban Fernández-Faith

Despite currently available treatment options for moderate-to-severe atopic dermatitis (AD), some patients fail to achieve adequate disease control. Emerging evidence suggests that mesenchymal stem cells (MSCs) may represent a promising therapeutic option. This systematic review and meta-analysis included four randomized controlled trials (RCTs) and one non-randomized clinical trial. Eligible studies evaluated patients with moderate-to-severe AD treated with MSCs derived from human umbilical cord blood, autologous …

13.08.2026journal-article

WORK: A Journal of Prevention, Assessment & Rehabilitation

Feasibility and functional benefits of a workplace short-burst walking intervention: A pilot study in sedentary middle-aged employees

Ravi Shankar Reddy

Background Prolonged sedentary behavior among office workers is associated with reduced physical function, increased fatigue, and decreased occupational well-being. Short-burst walking interventions have shown promise in counteracting these risks but require further evidence regarding their feasibility and functional impact in workplace settings. Objective To evaluate the feasibility and preliminary efficacy of a short-burst walking intervention on functional mobility and self-reported work outcomes among sedentary …

13.08.2026journal-article

LIFE: International Journal of Health and Life-Sciences

EFFECT OF RADIAL EXTRACORPOREAL SHOCK WAVE THERAPY ON MUSCLE POWER OUTPUT IN MAJOR THIGH MUSCLE GROUPS

Riki Tanaka, Kensei Tsujimoto, Tetsushi Moriguchi

Background: Radial extracorporeal shock wave therapy (rESWT) is widely used in sports medicine for pain relief and functional recovery; however, quantitative evidence regarding its immediate effects on neuromuscular performance in healthy athletes remains limited. Objective: To determine the acute effects of rESWT applied to the mid-quadriceps on isokinetic knee extension and flexion output in female university athletes. Methods: Eleven female university athletes (18–22 years) completed rESWT and control conditions …

13.08.2026journal-article

Frontiers in Neurology

Robot-assisted integrated cognitive-motor rehabilitation in patients with chronic stroke: a randomized controlled trial

Seungwoo Cha, Jiyeon Lee, Hyojin Jeon, Min Ho Chun

Background Cognitive and motor impairments are major determinants of functional independence after stroke. While robot-assisted training is effective for motor recovery, its impact on cognitive function through integrated cognitive–motor training remains less explored. This study evaluated the effects of an end-effector robot-assisted integrated cognitive–motor rehabilitation program on global cognitive function and upper limb motor outcomes in patients with chronic stroke. Methods In this single-center, randomized …

13.08.2026journal-article

Electronics

AS-Split Conformer: A Stage-Wise Convolution–Attention Framework with Mamba Decoder for End-to-End Speech Recognition

Lulu Qin, Xuan Fu, Mingchen Sun, Dadong Wang

Automatic speech recognition (ASR) systems based on Conformer architectures achieve strong performance by jointly modeling local acoustic patterns and global contextual dependencies. However, their interleaved convolution–attention design leads to progressive entanglement of fine-grained acoustic features and global semantic representations, which weakens monotonic alignment in speech recognition and degrades performance in long utterances. To address this limitation, we propose an AS-Split Conformer–Mamba framewor …

13.08.2026journal-article

Russian Journal of Cardiology

Efficacy of immunosuppressive therapy in the treatment of myocarditis and inflammatory cardiomyopathy. A systematic review

N. A. Varavin, E. M. Petrova, D. A. Volkova, I. A. Puzhalov, N. I. Gulyaev

Aim . To systematize published data evaluating the effectiveness of immunosuppressive therapy (IST) in the treatment of myocarditis and inflammatory cardiomyopathy. Material and methods. A systematic search was conducted for studies evaluating the effectiveness of IST in the treatment of myocarditis and inflammatory cardiomyopathy between 1995 and 2025. R e sults . Thirteen studies were included in the systematic review. Twelve studies found a positive effect of IST, including improved left ventricular (LV) ejectio …

13.08.2026journal-article

American Journal of Physical Medicine & Rehabilitation

Impact of Anterior Load Carriage on Dynamic Sagittal Spinal Alignment

Apurba Barman, Asghar Rezaei, Sandesh G. Bhat, Kenton R. Kaufman

Objectives: To examine the effects of anterior load carriage on dynamic sagittal spinal alignment during the gait cycle in younger (<65 y) and older (≥65 y) adults. Design: Cross-sectional study of 47 participants aged 20–80 years categorized as young and older adults. Participants walked at self-selected speeds with and without a 4.5 kg anterior chest load. Whole-body kinematics were recorded using a 19-camera infrared motion capture system. Outcome measures included lumbar lordosis (LL), thoracic kyphosis (TK), t …

13.08.2026journal-article

BMC Pulmonary Medicine

Age-related effects of comprehensive in-patient physiotherapy after lung cancer surgery across age groups: an ambispective observational cohort study in middle-aged and older patients

Ayse Sena Manzak Dursun, Betul Cinar, Fuat Gökdemir, Omer Soysal, Alis Kostanoğlu

Abstract Background Postoperative recovery after lung cancer surgery may be influenced by age, comorbidity burden, and perioperative rehabilitation strategies. However, evidence regarding the age-related effects of structured early inpatient physiotherapy programs remains limited. This study aimed to evaluate the age-related effects of a comprehensive in patient physiotherapy (CIPT) program on hospital length of stay (LoS), clinical parameters, symptom-related outcomes, and inflammatory biomarkers in patients under …

13.08.2026journal-article

Small

Delivery of Mitoxantrone by Biodegradable Cobalt‐Doped Hollow Prussian Blue Nanoparticles for Synergetic Photothermal Amplified Chemodynamic Therapy/Chemotherapy/Metalloimmunotherapy Against Tumor

Liyou Guo, Nannan Fu, Yuanyuan Fu, Shan‐Shan Xue, Yuxing Xie, Shili Zhou, Jinyang Wang, Qiuhua Li, Ming Li, Gen He, Dong‐Yang Zhang

ABSTRACT Immunotherapy has revolutionized antitumor treatment, but its effectiveness is severely compromised by the immunosuppressive tumor microenvironment (TME) and inadequate induction of antitumor immune responses, with most solid tumors remaining immunologically “cold” and unresponsive to monotherapies. Mitoxantrone (MTO), a first‐line chemotherapeutic agent, is additionally limited by poor bioavailability, acquired drug resistance, and insufficient immune activation. Herein, we developed biodegradable cobalt‐ …

13.08.2026journal-article

Cancer Gene Therapy

Targeting HDAC and proteostasis to eradicate quiescent cancer cells

Qi Jiang, Michelle Ertel, Austin Arrigo, Amjad Hijazzi, Sara Sannino, Jennifer L. Goeckeler-Fried, April Sagan, Ian Beddows, Betsy Ann Varghese, Daniel D. Brown, Wayne Stallaert, Adrian Lee, Amanda M. Clark, Hui Shen, Jeffrey L. Brodsky, Hatice U. Osmanbeyoglu, Ronald J. Buckanovich

Abstract Chemotherapy remains the primary treatment for ovarian cancer (OvCa), and chemoresistance drives patient mortality. Cellular quiescence, reversible exit from the cell cycle, increases chemotherapy resistance as chemotherapies primarily target rapidly proliferating cells. Here, we report that CHD4 and MBD3, components of the nucleosome remodeling and deacetylase (NuRD) complex, are downregulated in quiescent OvCa cells (qOvCa). We find that either CHD4 or MBD3 knockdown or histone deacetylase inhibitors (HD …

13.08.2026journal-article

Rehabilitation Counseling Bulletin

Family-Led Intervention in Improving Employment Outcomes for Persons With Intellectual Disabilities: CBT and MI: A Pilot Study

Abdoulaye Diallo, Lidia Fonseca, Omobolanle Wunuken, Diana Holland

This pilot randomized controlled trial examined whether a brief, family-led cognitive behavioral therapy and motivational interviewing intervention improved employment motivation among adults with intellectual disabilities. Intellectual disability is characterized by limitations in intellectual functioning and adaptive behavior, originating before age 18; it involves challenges in conceptual, social, and practical skills that affect everyday functioning. Fifty-two adults with moderate intellectual disability were r …

13.08.2026journal-article

OTJR: Occupational Therapy Journal of Research

How Patients Hospitalized for Chronic Obstructive Pulmonary Disease Exacerbation Understood Dyspnea Management in Acute Occupational Therapy

Yasunori Imaoka, Sho Maruyama, Syota Matsumoto, Keita Yuba, Osamu Hataji

This qualitative study explored how patients hospitalized for chronic obstructive pulmonary disease (COPD) exacerbation interpreted dyspnea-management strategies learned during acute occupational therapy (OT) and how they related those strategies to anticipated use after discharge. Semi-structured interviews were conducted before discharge with 15 patients, 14 of whom were male, who received acute OT at a single acute care hospital in Japan, and the data were analyzed using reflexive thematic analysis. Patients des …

13.08.2026journal-article

Turkish Journal of Medical Sciences

Association of occupational lead exposure with erythrocytic parameters and nitric oxide–related metabolites: a case-control study ​​

MELİH GAFFAR GÖZÜKARA, SERVET BİRGİN İRİTAŞ, DENİZ ÖZKAN VARDAR, LÜTFİYE TUTKUN, ÖZLEM İRİTAŞ, SERDAR DENİZ, VUGAR ALİ TÜRKSOY, ENGİN TUTKUN

Background/aim: Occupational lead (Pb) exposure remains a significant public health concern due to its persistent presence in industrial environments and its cumulative toxic effects. Although the hematological and neurological consequences of Pb exposure are well documented, early vascular effects and the mechanisms associated with potential endothelial impairment remain unclear. This study aimed to investigate the associations between Pb exposure, erythrocytic parameters, and nitric oxide (NO)–related metabolites …

13.08.2026journal-article

Blood Cancer Discovery

Sequenced, Not Stirred: Positioning CAR T and Bispecific Antibody Therapy in Multiple Myeloma

Rahul Banerjee

Summary: In this issue of Blood Cancer Discovery, Merz and colleagues study more than 600 recipients of chimeric antigen receptor T-cell (CAR T) and/or bispecific antibody therapy in multiple myeloma with an emphasis on patients who received both modalities sequentially. They find a clear progression-free survival advantage when CAR T therapy was used first; importantly, because outcomes with both modalities were similar when following progression after the converse modality, this advantage was driven by CAR T ther …

13.08.2026journal-article

Stroke: Vascular and Interventional Neurology

At-Home BCI Rehabilitation Therapy for Chronic Upper Extremity Deficit After Stroke (BCI-REHAB): A Randomized Trial

Eric C. Leuthardt, Seth J. Wilk, Lauren Souders, Kelly B. Carr, Robert Coker, Gregory E. Wilding, Dorothee Zuleger, Benjamin T. Acland, Alexandre R. Carter

BACKGROUND: At-home stroke rehabilitation methods have strong potential to supplement limited clinical resources, but realizing that potential for survivors in the chronic phase of recovery requires developing and validating more effective options than the home exercise programs typically used today. BCI-REHAB (At-Home BCI Rehabilitation Therapy for Chronic Upper Extremity Deficit After Stroke) compared an at-home brain-computer interface (BCI) therapy system (IpsiHand System) versus an at-home exercise program for …

13.08.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

CANCELAMENTO VIRTUAL: UMA VIA (IN)ADEQUADA DE COMBATE AO DISCURSO DE ÓDIO

Nayanna Priscilla Silva Bezerra Guerra, Cleide Alves de Souza, José Welhinjton Cavalcante Rodrigues

Este artigo trata sobre a problemática da adoção do cancelamento virtual como ferramenta de combate ao discurso de ódio. Para atingir os objetivos deste trabalho, foi adotada como metodologia a pesquisa bibliográfica, utilizando-se de artigos científicos, dissertação e livros que tratam acerca da eugenia, discurso de ódio e cancelamento virtual, cuja análise dos trabalhos se deu por meio de uma abordagem qualitativa, de modo a oferecer esclarecimentos relativos aos alvos propostos. As reflexões proporcionadas por e …

13.08.2026journal-article

Journal of Education and Research in Nursing

Assessment of Post-Earthquake Trauma and Coping Strategies for Earthquake-Related Stress Among Midwifery Students

Beril Nisa Yaşar, Sibel İçke

Background: Earthquakes are major sources of psychological stress that can adversely affect university students' personal and professional lives. Aim: This study aimed to assess post-earthquake trauma levels and coping strategies among midwifery students. Methods: This cross-sectional study included 251 midwifery students enrolled at a state university (participation rate: 71.71%). Data were collected online using the Introductory Information Form, the Scale that Determines the Level of Trauma After the Earthquake, …

13.08.2026journal-article

Jurnal Kegawatdaruratan Medis Indonesia

Comparison of Animated Videos and E-Pocket Books Regarding Occupational Health and Safety Knowledge Among Anesthesia Nursing Students

Nurul Fadila Sofyan, Ratih Kusuma Dewi, Niken Anggraini Sri Saputri

Background: Occupational Safety and Health (OSH) is a crucial aspect of anesthesiology practice. Anesthesia students need to understand OSH principles early, given their exposure to physical, chemical, biological, and ergonomic hazards in the workplace. The high number of workplace accidents in Indonesia (462,241 cases in 2024) highlights the need for effective learning media. Animated videos and e-pocket books are important because they provide engaging, flexible, and repeatable learning experiences that can impro …

13.08.2026journal-article

BMC Sports Science, Medicine and Rehabilitation

How many athletes are enough? Small-sample instability of reliability indices and the minimum sample size for a trustworthy minimal detectable change in two-trial sport field tests: a Monte Carlo study

İrfan Marangoz

Abstract Background Test-retest reliability of sport and rehabilitation field tests is usually reported from very small samples, yet how unstable the resulting indices are, and how many participants are needed, is rarely quantified. We used Monte Carlo simulation to evaluate relative (intraclass correlation coefficient, ICC) and absolute (minimal detectable change, MDC₉₅) reliability statistics under sport-realistic small-sample conditions. Methods Two-trial data were simulated for a counter-movement-jump-like meas …

13.08.2026journal-article

Jurnal Informatika dan Teknik Elektro Terapan

IMPLEMENTASI DEEP LEARNING HYBRID RESNET50V2-BIGRU PADA APLIKASI WEB VISUAL SPEECH RECOGNITION BAGI KOMUNITAS TULI

Salma Nurfauziah

Visual Speech Recognition (VSR) merupakan teknologi komunikasi krusial bagi komunitas Tuli, terutama di lingkungan bising di mana sistem berbasis audio gagal berfungsi. Pengembangan VSR untuk bahasa Indonesia menghadapi tantangan kelangkaan dataset audio-visual dan tingginya ambiguitas kata homofon. Selain itu, tingginya beban komputasi data video seringkali menghambat implementasi pada platform web. Oleh karena itu, penelitian ini bertujuan mengembangkan sistem VSR bahasa Indonesia yang efisien menggunakan arsitek …