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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
04.08.2026journal-article

PLOS One

Influence of the timing of brief, high-intensity cycling exercise on memory for novel words presented during an initial Portuguese lesson among older adolescents with ADHD: An exploratory study

M. David Diggs, Daniel Ferreira da Silva, Robert Moser, Melissa J. McGranahan, Patrick J. O’Connor

This exploratory study examined whether brief high-intensity cycling exercise, performed either before or after a single online Portuguese language lesson, improved language acquisition or retention in older adolescents with ADHD, compared to a resting control condition. Participants (n = 29; mean age 19.2; no prior Portuguese knowledge) were randomly assigned to one of the three conditions: control, exercise before, and exercise after. The 29-minute Portuguese lesson introduced vocabulary, grammar, and syntax. Imm …

04.08.2026journal-article

Journal of the American Heart Association

Risk Factors for Coronary Heart Disease and Stroke Among Older Adults With Metabolic Dysfunction–Associated Steatotic Liver Disease: A Nationwide Cohort Study

Sangwook Cheon, Seohui Jang, Eun Seok Kang, Jihun Song, Jaewon Khil, Seokjin Kong, Yihyun Kim, Jin Hyun Park, Minjeong Kang, Jeongin Lee, Taeho Kwak, Hye Jun Kim, Jinhyeok Choi, Hwamin Lee, Seogsong Jeong

Background Older adults with metabolic dysfunction–associated steatotic liver disease have elevated cardiovascular disease (CVD) risk, yet conventional models, such as the Framingham Risk Score, rely on linear assumptions and were developed for younger populations. Nonlinear machine learning approaches may improve risk prediction in this high‐risk group. Methods Using Korean National Health Insurance Service data, this population‐based cohort study followed up 67 575 adults, aged ≥65 years, with metabolic dysfuncti …

04.08.2026journal-article

Psicologia e Saúde em debate

RESTRIÇÃO DOMICILIAR E VULNERABILIDADE SOCIOFUNCIONAL DE IDOSO COM LIMITAÇÃO FÍSICA: Estudo de caso na Atenção Primária

Maynara Ribeiro Mengatto, Mirian Dombrowski Dreher, Samira Fuck Yussuf, Maria Solange Ferreira Alves, Fabrício Cardoso

O envelhecimento populacional impõe desafios à Atenção Primária à Saúde, sobretudo quando limitações funcionais coexistem com vulnerabilidades sociais. Objetivo: Analisar as vulnerabilidades sociofuncionais identificadas em um idoso acompanhado pela Atenção Primária à Saúde, considerando a interação entre limitação funcional, barreiras ambientais e rede de apoio. Método: Estudo qualitativo, de natureza descritivo-exploratória, delineado como estudo de caso único e realizado em uma Unidade Básica de Saúde de Joinvil …

04.08.2026journal-article

Journal of Clinical Medicine

Motor-Sparing Regional Analgesia in Frail and Sarcopenic Older Adults Undergoing Total Knee Arthroplasty: From Anatomy to Clinical Decision-Making—A Narrative Review

Paweł Pietraszek, Tomasz Reysner, Anna Kluzik, Anna Perek, Justyna Marszałek-Buko, Alicja Bartkowska-Śniatkowska, Katarzyna Wieczorowska-Tobis, Malgorzata Reysner

Total knee arthroplasty (TKA) is increasingly performed in older adults, a population with a growing prevalence of frailty and sarcopenia. Analgesic strategies focused mainly on pain reduction may overlook mobility, functional independence, fall prevention, and delirium risk, making motor preservation a central goal of perioperative care. This narrative review examines the anatomical basis, clinical evidence, and practical application of motor-sparing regional analgesia for older adults undergoing TKA, with emphasi …

04.08.2026journal-article

Frontiers in Aging Neuroscience

Emerging neuroprotective mechanisms and therapeutic potential of natural polysaccharides in Alzheimer's disease

Noor Muhammad, Rui Ai, Limin Yang, Yuelong Cui, Liqiang Wang, Shaoting Weng, Yao Wang, Mohib Ullah Kakar, Suliman Khan, Sajjad Ahmad, Imran Iqbal

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss, affecting millions worldwide. Despite extensive research, effective treatments remain limited. Polysaccharides, abundant biological macromolecules derived from natural resources have emerged as promising therapeutic candidates due to their antioxidant, anti-inflammatory, and neuroprotective properties. This narrative review summarizes recent preclinical and limited clinical evidence on natural po …

04.08.2026journal-article

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences

Modeling Dynamic Walkability to Support Time-Based Route Planning for Older Adults

Febrian Fitryanik Susanta, Pei-Fen Kuo, I. Gede Brawiswa Putra

Abstract. Walkability assessments for elderly pedestrians are often based on static representations of the built environment, overlooking temporal variations that influence walking conditions throughout the day. This study develops a network-based dynamic walkability framework that integrates static infrastructural characteristics with time-dependent environmental factors to capture spatiotemporal variability in pedestrian suitability. The approach combines sidewalk and arcade-based pedestrian networks with dynamic …

04.08.2026journal-article

International Journal of Advanced Multidisciplinary Research and Studies

Effectiveness of Cognitive Sensorimotor Exercise in Reducing Fear of Falling Among Older Adults

Ryan Firnanda, Dara Febriana, Marlina .

Fear of falling is a common co ncern among older adults that can reduce mobility, independence, and quality of life. This study aimed to evaluate the effect of cognitive sensorimotor exercise on fear of falling in older adults. A quasi-experimental study with a one-group pretest-posttest design was conducted among 38 older adults at Panti Sosial Lanjut Usia Geunaseh Sayang, Banda Aceh, Indonesia, selected using purposive sampling. Participants performed cognitive sensorimotor exercise for 30 minutes per session, fi …

04.08.2026journal-article

Journal of the American Geriatrics Society

Evaluation of Hospital Readmission and Mortality Risk in Older Frail Patients Using the FIB ‐4 Index: A Cohort Study

Stefano Rizza, Gianluigi Ferrazza, Susanna Longo, Maria Postorino, Andrea Quatrana, Tommaso Rinaldi, Sara Martina, Alessandro Nucera, Massimo Federici

ABSTRACT Background Recurrent hospitalizations and mortality are frequent among frail older adults, reflecting reduced physiological reserve and vulnerability to stressors. Identifying inexpensive and readily available biomarkers for risk stratification remains a priority in geriatric medicine. The Fibrosis‐4 (FIB‐4) index, originally developed to estimate liver fibrosis, has recently emerged as a systemic risk marker beyond hepatic disease. Methods We conducted a prospective observational study including 248 hospi …

03.08.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

INCLUSÃO DAS PESSOAS COM AUTISMO NO MERCADO LABORAL: MAPEAMENTO SISTEMÁTICO DE PRODUÇÃO CIENTÍFICA

Davi Milan, Tayná Fabiano da Silva Souza, Diene da Silva Schlickmann, Claudete Maria do Carmo Sartoretto Soares, Rosimeire Martins de Paula, Edna Maria da Silva Oliveira

O objetivo do artigo é realizar mapeamento sistemático da produção científica, modalidade de estudo bibliométrico, sobre o tema inclusão laboral do autista, dos artigos das bases Scopus e Web of Science. tendo como Enquadramento teórico a realização do mapeamento sistemático da produção científica – análise bibliométrica sobre autismo e mercado laboral. A metodologia utilizada foi a submissão de string de busca nas bases, geração de arquivos com dados bibliométricos; mescla de dados das bases e retirada de dados du …

03.08.2026journal-article

Ijtimoiy-gumanitar sohada ilmiy-innovatsion tadqiqotlar

YOSHLARDA NIKOH QURISH MOTIVLARINING OILA MUSTAHKAMLIGIGA TA’SIRINING PSIXOLOGIK XUSUSIYATLARI

Nodira Shodiyeva

This study examines the formation of marriage motives among young people and their psychological influence on the stability of marital relationships and family strength. Particular attention is paid to the relationship between marriage motivation and such factors as love and emotional intimacy, mutual respect, psychological and spiritual compatibility, social status, material interests, parental and social influence, avoidance of loneliness, and the desire to continue the family lineage. The study substantiates tha …

03.08.2026journal-article

BMC Geriatrics

Network analysis of frailty, sleep quality, and life satisfaction in older patients: a cross-sectional study stratified by chronic disease burden

Zhiqiang Wang, Zhanhua Wei, Xiaoya Li, Mengqiu Hu, Kaiqin Deng, Tong Cheng, Limeng Zhao, Xu Han, Zhiru Liang, Jing Wang, Shuping Zhao

Abstract Background Multimorbidity and chronic disease burden are common among older patients and are closely associated with frailty, poor sleep, and reduced subjective well-being. However, total-score-based analyses may obscure item-level interactions across health domains. This study examined the network structure of frailty, sleep quality, and life satisfaction in older patients and explored whether association patterns varied across chronic disease burden levels. Methods This cross-sectional study included 1,1 …

03.08.2026journal-article

Frontiers in Nutrition

Associations of magnesium intake and a magnesium-rich diet score with sarcopenia in middle-aged and older Korean adults: potential mediation by C-reactive protein

Sooyeun Choi, Youjin Je

Background/objectives Dietary magnesium, primarily derived from plant foods, has been inconsistently associated with sarcopenia, and the underlying mechanisms have rarely been explored. Although foods and dietary patterns may act synergistically, to our knowledge, no previous study has jointly examined magnesium intake and a magnesium-rich dietary pattern in relation to sarcopenia. We investigated whether dietary magnesium intake and a magnesium-rich diet score were associated with sarcopenia in middle-aged and old …

03.08.2026journal-article

Cadernos para o Professor

ALFABETIZAÇÃO E LETRAMENTO NA EDUCAÇÃO DE JOVENS E ADULTOS: o uso de gêneros textuais

Tatiane Reis de Oliveira Balbi

RESUMO: A alfabetização e o letramento são termos muito discutidos atualmente na docência, para que haja um ensino de qualidade. Então, pretende-se pensar nessas perspectivas na educação de jovens e adultos (EJA). O objetivo principal do trabalho é incentivar a reflexão sobre a prática docente no contexto da EJA, em que o processo de alfabetização seja indissociável do letramento, a partir do uso de gêneros textuais. Assim, será possível valorizar as vivências e conhecimentos prévios dos alunos, com a utilização de …

03.08.2026journal-article

Programming Historian

Using Linked Open Data to Describe Academic Journals and People with Wikidata

Cláudia De Souza, Dinah M. Wilson Fraites

This lesson introduces Wikidata and provides a step-by-step guide to using linked open data to create and link metadata about academic journals and people. It explores best practices for managing metadata in Wikidata to increase the visibility and accessibility of resources in digital environments.

03.08.2026journal-article

Journal of Personalized Medicine

Multimodal Correlates of Longitudinal Functional Decline in Behavioral Variant Frontotemporal Dementia (bvFTD)

Electra Chatzidimitriou, Georgios Ntritsos, Eleni Poptsi, Emmanouil Tsardoulias, Andreas L. Symeonidis, Magda Tsolaki, Panos Charalambous, Chrissa Sioka, Eleni Aretouli, Ioannis Iakovou, Katherine P. Rankin, Panagiotis Ioannidis, Despina Moraitou

Background and Objectives: Functional decline is a major determinant of disability, caregiver burden, and loss of independence in behavioral variant frontotemporal dementia (bvFTD). Although bvFTD is characterized by early and rapidly progressive deterioration in everyday functioning, the multimodal contributors associated with longitudinal functional change remain insufficiently understood. The present study aimed to identify the strongest cognitive, behavioral, personality, and neuroimaging correlates of longitud …

03.08.2026journal-article

Frontiers in Aging Neuroscience

Pericarotid fat density: a novel predictor of cognitive and functional outcomes in cerebral small vessel disease

Shuo Zhao, Jing Zhang, Xunyao Hou, Xinyao Wang, Hui Gu, Chuanchen Zhang, Yunliang Guo, Ximing Wang

Background Pericarotid fat density (PFD) obtained by computed tomography angiography (CTA) could serve as a surrogate biomarker reflecting local inflammation. The study aimed to quantitatively estimate the impact of PFD on cognitive and functional outcomes in patients with cerebral small vessel disease (CSVD). Methods A total of 71 symptomatic and 55 asymptomatic CSVD patients were prospectively recruited. Imaging characteristics comprising CSVD markers and carotid artery markers (PFD values, calcification, stenosi …

03.08.2026journal-article

Cells

Mitochondrial Dysfunction as a Driver of Meta-Inflammation in Aging: The Emerging Role of PDK4 in Bioenergetic Reprogramming and Inflammatory Amplification

Md Riad Chowdhury, Gui-Hwa Jeong, In-Kyu Lee

Aging is accompanied by a progressive decline in mitochondrial quality, bioenergetic flexibility, and stress resilience. Aging mitochondria are increasingly recognized as active inflammatory signaling platforms rather than passive targets of cellular damage. Excess mtROS, leaked mtDNA, defective mitophagy, altered NAD+ metabolism, and impaired pyruvate oxidation together create a cellular environment that favors persistent inflammatory activation. These signals engage NF-κB, NLRP3 inflammasome, cGAS–STING, and SASP …

03.08.2026journal-article

Frontiers in Public Health

Current status and influencing factors of early delayed neurocognitive recovery in older adult patients after major orthopedic surgery under general anesthesia: a cohort study

Siyu Yan, Dan Zhou, Yinghao Zhou, Lei Song, Xiaolin Xu, Jiamin Wang, Lin Zhao

Objective To investigate the current status of early delayed neurocognitive recovery (dNCR) in older adult patients after major orthopedic surgery in China and analyze its influencing factors, providing a reference for early intervention by clinical workers. Design Observational cohort study. Methods A convenience sampling method was used to select patients aged 60 years or older who underwent major orthopedic surgery under general anesthesia at a tertiary hospital in Qingdao, Shandong Province, from September 2025 …

03.08.2026journal-article

Work and Health

Health-Related Work Capacity and Labor Participation Among Middle-Aged and Older Adults in China: Evidence From CHARLS

Ying Wang, Yutong Wu, Tianyu Wang, Wenhao Deng

Background: In the context of population ageing and retirement policy reform, sustaining labor participation among middle-aged and older adults has become an important socioeconomic issue. This study examined the association between health-related work capacity and labor participation among Chinese middle-aged and older adults. Methods: Data were drawn from the China Health and Retirement Longitudinal Study (CHARLS). The study included 6600 middle-aged and older adults (mean age, 63 years; 51% female). Labor partic …

03.08.2026journal-article

Frontiers in Nutrition

Targeting cellular senescence through nutritional senotherapeutics in brain aging and neurodegenerative diseases

Verónica Salas-Venegas, Norma E. López-Diazguerrero, Ricardo J. Ramírez-Carreto, Mina Konigsberg, Anahí Chavarría

Cellular senescence has emerged as a key contributor to brain aging and neurodegenerative diseases, which are increasing in prevalence as life expectancy rises. Senescent cells accumulate in multiple brain cell populations and secrete the senescence-associated secretory phenotype (SASP), promoting chronic neuroinflammation, mitochondrial dysfunction, blood–brain barrier disruption, and progressive neuronal damage. This review examines the role of cellular senescence in brain aging and neurodegenerative diseases and …

03.08.2026journal-article

Progress in Additive Manufacturing

Effect of aging temperature on the microstructure and tribological behavior of an 18Ni maraging steel manufactured by laser powder bed fusion (LPBF)

José Wilmar Calderon-Hernández, Fábio Faria Conde, Maryory Astrid Gómez Botero, Jorge Mauricio Sepúlveda Castaño, Alexander Zuleta Durango, Daniela Passarelo Moura da Fonseca, Julian Arnaldo Avila

Abstract This study addresses the critical knowledge gap regarding the influence of kinetically controlled austenite reversion on the tribological stability of Laser Powder Bed Fusion (LPBF) 18Ni-300 maraging steel. While conventional aging focuses on peak hardness (450–550 °C), this research investigates the high-temperature aging regime (610 °C and 650 °C) to elucidate the correlation between phase meta-stability and the evolution of protective tribo-layers. Samples were characterized using LOM, SEM, and XRD, wit …

03.08.2026journal-article

Journal of Community Medicine and Public Health Research

Impact of HIV/AIDS on Quality of Life in People Living with HIV (PHLV) and Their Caregivers’ – A Mix Method Study

Binal Prajapati, Parimal Gurjar, Krunal Modi, Dhiren Amin, Devanshi Jani

Antiretroviral therapy (ART) has changed the life expectancy of PLHIV patients, but not the quality of life (QoL). Caregivers of PLHIV are also facing social rejection, stigma, and many more problems, similar to those of PLHIV patients. The study was designed as a mixed-method study to document the Quality of life of HIV/AIDS Patients in a tertiary care hospital. The first aspect was the quantitative part, which included the World Health Organization Quality of Life Brief Version (WHO QoL BREF), which focused on th …

03.08.2026journal-article

Успехи геронтологии

ДИНАМИКА ГЕРИАТРИЧЕСКОГО СТАТУСА ПОЖИЛЫХ ПАЦИЕНТОВ В УСЛОВИЯХ ДЛИТЕЛЬНОЙ ГИПОМОБИЛЬНОСТИ В ПЕРИОД ПАНДЕМИИ COVID-19

А.С. Рукавишников, О.М. Кузьминов, С.Г. Горелик, Д.П. Пискунов

Пандемия COVID-19 и введённые в этот период ограничительные меры оказали существенное влияние на состояние здоровья лиц пожилого возраста. В этой связи особый интерес представляет оценка изменений гериатрического статуса, в частности перехода от состояния преастении к сформированному синдрому старческой астении, в условиях длительного ограничения двигательной активности и социальной изоляции. Цель исследования — анализ динамики гериатрического статуса пациентов пожилого возраста при продолжительном пребывании в усл …

03.08.2026journal-article

JMIR Formative Research

COVID-19 Impact on Health Behaviors and Survey Engagement in Older African Americans: Longitudinal Cohort Study

Selda Yildiz, Nora Mattek, Joel Steele, Sarah Gothard, Bryan D James, Ana W Capuano, Lisa L Barnes, Jeffrey A Kaye, Zachary T Beattie

Background The COVID-19 pandemic disrupted older adults’ daily lives, particularly concerning social interaction, physical activity, and sleep quality. Older African Americans were disproportionately affected yet remain underrepresented in research documenting the impact of the COVID-19 pandemic. Objective This study investigated changes in self-reported health, survey engagement, physical activity, and sleep duration among older African American adults in the Minority Aging Research Study (MARS) before and after I …