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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
30.08.2026journal-article

Bipolar Disorders

Optimizing Ketamine Infusion Therapy for Treatment‐Resistant Bipolar Depression: Commentary on Zhou et al. (2023)

Chih‐Cheng Lin, Lien‐Chung Wei

ABSTRACT Objectives To contextualize the real‐world findings of repeated intravenous ketamine infusions for treatment‐resistant bipolar depression (TRBPD) and identify priorities for safer, more durable clinical implementation. Methods We provide a focused commentary on Zhou et al. (2023) and integrate selected evidence concerning inflammatory and metabolic correlates, neurocognitive outcomes, and continuation‐phase ketamine treatment. Results Repeated subanesthetic ketamine infusions may rapidly improve depressive …

30.08.2026journal-article

Journal of Hospital Medicine

Sharing unwritten rules of negotiation: An effort to help leaders thrive

Julie Byerley, Kenya McNeal‐Trice, Nancy D. Spector

Abstract Negotiation is a skill essential for leader success yet not often trained in the academic pathway. Ideal negotiation is between at least two parties with overlapping goals where mutual benefit is achieved in a solidified agreement. For long‐term success in partnership, integrity, shared value, mutual respect, and clarity should be demonstrated during negotiation, propelling the professional relationship going forward. Negotiation is a skill often addressed in senior leadership development programs. For exa …

30.08.2026journal-article

Artificial Organs

SURGELLA: A Scoping Review of Impella‐Assisted Hemodynamic Support in High‐Risk Non‐Cardiac Surgery

Hussein Elghazaly, Mohammed Allaf, Areeb Mian, Hanad Ahmed, Alex Gordon‐Weeks, Alexander Tindale, Vasileios Panoulas

ABSTRACT Background Patients with advanced heart failure or severe ventricular dysfunction are often considered prohibitively high risk for non‐cardiac surgery. Impella may provide temporary perioperative hemodynamic support by augmenting cardiac output and unloading the left ventricle, but evidence for this strategy remains limited and largely case based. Methods We conducted a scoping review of Impella use for adult high‐risk non‐cardiac surgery. MEDLINE and Embase were searched from inception to April 2026, with …

30.08.2026journal-article

Journal of Clinical Medicine

Persistent Unilateral Nephrolithiasis: Do 24-h Urine Parameters Account for It?

Orel Hemo, Miki Haifler, Asaf Shvero, Nir Kleinmann, Dorit E. Zilberman

Background: Bilateral nephrolithiasis is typically attributed to systemic metabolic abnormalities reflected in 24 h urine studies. Yet, some individuals form stones exclusively in one kidney over long-term follow-up, while the contralateral kidney remains unaffected. This study aimed to determine whether differences in urinary metabolites can explain persistent unilateral stone formation. Methods: We retrospectively reviewed our 2011–2024 nephrolithiasis database and analyzed 24 h urine compositions obtained under …

30.08.2026journal-article

Ukrainian Heart Journal

Оцінка ефективності й безпечності використання аксилярної канюляції при хірургічному лікуванні патології грудної аорти

O. V. Zelenchuk

The aim – to evaluate the efficacy and safety of direct axillary artery cannulation during reconstructive surgery for thoracic aortic disease by comparing intraoperative parameters, early clinical outcomes, and the incidence of neurological and local complications with those of femoral artery cannulation.Materials and methods. The study included 110 patients who underwent reconstructive surgery for thoracic aortic disease between 2016 and 2025 using peripheral arterial cannulation. Femoral artery cannulation was pe …

30.08.2026journal-article

World Journal of Surgery

Correlation Between Anastomotic Leakage and the Anastomotic Position of the Gastric Conduit After Esophagectomy Using ICG Fluorescence Imaging Stratification

Yamato Ninomiya, Kazuo Koyanagi, Rie Nakashima, Kohei Tajima, Kohei Kanamori, Mika Ogimi, Yoshiaki Shoji, Akihito Kazuno, Miho Yamamoto, Masaki Mori

ABSTRACT Background This study aimed to clarify the correlation between anastomotic leakage and anastomotic position after esophagectomy for esophageal cancer, stratified by gastric conduit blood flow assessed using indocyanine green (ICG) fluorescence imaging. Methods A total of 136 patients who underwent esophagectomy with retrosternal gastric conduit reconstruction were included. After creating the gastric conduit, three points were identified: point A (anastomotic site), point B (terminal end of the gastroepipl …

30.08.2026journal-article

Journal of Clinical Medicine

Population Decline May Affect the Incidence of Pulmonary Tuberculosis in Japan

Akihiro Miyauchi, Mizuki Inaba, Takatoshi Tetsuka, Noritaka Sakamoto, Yushi Nomura, Otohiro Katsube, Hirokuni Hirata, Hiroshige Yoshioka, Seiji Niho, Kumiya Sugiyama

Background/Objectives: Pulmonary tuberculosis in Japan had been decreasing as a result of the country’s anti-tuberculosis policy. The decreased number of patients with tuberculosis has led to many tuberculosis units being downsized. However, the decreasing trend in incidence ended in 2022. To resume this trend, it is important to clarify which populations are at higher risk of developing tuberculosis. Methods: This study analyzed annual reports on tuberculosis published by the Japanese government from 2015 to 2024. …

30.08.2026journal-article

Machines

Imbalanced Fault Diagnosis of Harmonic Reducers Using Vibration Signals Based on an Auxiliary Classifier WGAN-GP with Spectral Normalization

Lingdong Wang, Ronggang Yang, Jianlong Wang, Kai Li, Jiawei Xiang, Lishan Gao

Class imbalance is common in vibration-based fault diagnosis because normal-condition data are generally more abundant than fault data. This study proposes an auxiliary-classifier Wasserstein generative adversarial network with gradient penalty and spectral normalization, termed ACWGAN-SG, for fault-sample generation and progressive dataset augmentation. The method combines class-conditioned generation, Wasserstein adversarial learning, gradient penalty, spectral normalization, and PCC-CS-based sample screening. Ex …

30.08.2026journal-article

Journal of Pastoral Care & Counseling: Advancing theory and professional practice through scholarly and reflective publications

Van Gogh, Cowper, and Unfinished Suffering: Narrative Hope in Clinical Chaplaincy

Hyewon Kim

This clinical pastoral reflection explores how historical and artistic narratives may support meaning-making in chaplaincy encounters. During a pastoral visit with a patient experiencing advanced cancer and depression, the lives of Vincent van Gogh and William Cowper became interpretive resources through which suffering was reframed as spiritually continuous rather than spiritually disqualifying. The encounter illustrates how narrative engagement can foster renewed hope while suffering remains unresolved within cli …

30.08.2026journal-article

IPS Journal of Basic and Clinical Medicine

Navigating the Gap: A Review of Time to Treatment Intervals and Cervical Cancer Survival in Sub-Saharan Africa

Bright Odinaka Okorocha, Chigaemezu Remmy-Martin Akubuo, Abdulhafeez Opeyemi Busari, Lovelyn Chiamaka Nnanyereugo, John Perpetual Chimazuru, Confidence Chinaza Ogbomade, Victory Mmerichukwu Ogbatuo

Background: While cervical cancer is highly preventable through the HPV vaccine, early detection, and treatment, it continues to be a significant contributor to the morbidity and mortality of women in Sub-Saharan Africa (SSA). Poorer survival outcomes in SSA compared to high-income countries can, to a large extent, be attributed to patients being unable or unwilling to present to the health system to obtain curative treatment in a timely manner. Time-to-treatment interval (TTI) has gained traction as a key measure …

30.08.2026journal-article

Journal of Cardiovascular Electrophysiology

Clinical Outcomes After Catheter Ablation in Patients With Structural Heart Disease and Ventricular Fibrillation

Kenji Hashimoto, Samual Turnbull, Saurabh Kumar

ABSTRACT Introduction In patients with ischemic cardiomyopathy (ICM), recurrent VF may be treated with catheter ablation by targeting triggering premature ventricular complexes (PVCs) and/or ventricular scar homogenization. Data on optimal ablation strategies in patients with non‐ischemic cardiomyopathy (NICM) remain limited. This study aimed to compare ablation strategies and outcomes in patients with recurrent VF due to ICM versus NICM. Methods and Results We retrospectively analyzed consecutive patients with str …

30.08.2026journal-article

IECCMEXICO

Occult Osteochondral Injuries in Athletes: Advanced Imaging, Clinical Evolution, and Criteria for Safe Return to Sport

Jose Gregorio Requena Rodriguez, Loys Eliana Tello Caldas, Edunice Beatriz Mora López, Juan Pablo Monroy Moreno, Angie Michelle Junco Aguaiza, Juan José Dorado Victoria, Fabián Patricio Miranda Yáñez, Jorge Roberto Gandarilla San Luis, Nicolás Camilo Rivera Calvo, Eduardo Andres Castillo González

Occult osteochondral lesions represent an important challenge in sports medicine because they may remain undetected during initial assessment despite persistent pain, swelling, mechanical symptoms, and functional limitation. This study analyzed the role of diagnostic imaging, clinical and structural evolution, and return-to-sport criteria in athletes with osteochondral injuries, with particular emphasis on the knee and ankle. An integrative descriptive and analytical review was conducted using the Scientific Method …

30.08.2026journal-article

Journal of the American Heart Association

Natriuretic Peptide and Transthyretin and Their Relationship With Clinical Outcomes: Results From ATTRIBUTE‐CM, a Randomized Controlled Trial

Onyedika John Ilonze, Daniel Philip Judge, Ahmad Masri, Prem Soman, Francesco Cappelli, Michel Georges Khouri, Nitasha Sarswat, Mazen Hanna, Yuxi Liu, Gillian Murtagh, Kuangnan Xiong, Adam Castaño, Jean‐François Tamby, Jonathan C. Fox, Uma Sinha, Jan Marie Griffin, Julian D. Gillmore, James Louis Januzzi

Background Transthyretin amyloid cardiomyopathy (ATTR‐CM) carries high risk for all‐cause mortality (ACM), cardiovascular mortality (CVM), and cardiovascular hospitalization (CVH). NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide) and serum TTR (sTTR) are prognostic biomarkers in transthyretin amyloid cardiomyopathy, but their combined value for integrated risk stratification remains unknown. We evaluated the relationship between baseline NT‐proBNP and sTTR and their prognostic value in ATTRIBUTE‐CM (Efficacy a …

30.08.2026journal-article

Biomedicines

Long-Duration Response to Levodopa in Patients with Early Parkinson’s Disease: Pharmacodynamics, Neuroplasticity, and Clinical Implications

Giorgia Sciacca

Background: The most effective pharmacological treatment for Parkinson’s disease (PD) remains levodopa, whose responsiveness is distinguished into two temporally and mechanistically distinct components: the short-duration response (SDR), which lasts hours, closely paralleling drug plasma concentration, and the long-duration response (LDR), which derives from prolonged administration of levodopa and persists for days to weeks after drug discontinuation. The mechanisms underlying the LDR and, in particular, the behav …

30.08.2026journal-article

JAMA

Low-Voltage Ablation in Persistent Atrial Fibrillation

Astrid Paul Nordin, Emmanouil Charitakis, Carina Carnlöf, Finn Åkerström, Ott Saluveer, Henrik Almroth, Lars O. Karlsson, Anders Hassel Jönsson, Csaba Herczku, Jari Tapanainen, Niklas Höglund, Emma Svennberg, Frieder Braunschweig, Tara Bourke, Jonas Schwieler, Hamid Bastani, Serkan Saygi, Fahd Asaad, Yusuf Türkmen, Mats Jensen-Urstad, Nikola Drca

Importance Pulmonary vein isolation remains the foundational ablation approach for atrial fibrillation (AF), yet outcomes in persistent AF remain suboptimal. Targeting low-voltage zones identified by electroanatomical mapping offers a promising strategy for enhancing ablation success. Objective To determine whether adjunctive individualized low-voltage zone ablation improves arrhythmia outcomes and health-related quality of life beyond pulmonary vein isolation alone in patients with persistent AF and significant lo …

30.08.2026journal-article

Clinical Case Reports

Malaria‐Associated Secondary Hematophagocytic Lymphohistocytosis—A Case Report and Comprehensive Literature Review (sHLH)

Indresh Yadav, Sulav Kumar Jha, Sweta Singh, Dipesh Kumar Mandal, Saurav Jha

ABSTRACT Malaria‐associated secondary HLH, though rare, is often overlooked. Clinicians should maintain a high‐index of suspicion in travelers returning from malaria‐endemic regions who develop severe to rapidly worsening inflammatory illness, as early recognition is critical for survival.

30.08.2026journal-article

Wilderness & Environmental Medicine

Epinephrine Autoinjectors as an Improvised Treatment for Severe Asthma in Austere Settings

Kenneth V. Iserson

Severe asthma exacerbations may rapidly become fatal when bronchodilator therapy is unavailable. In wilderness and disaster environments, inhaled β 2 -agonists—the standard treatment—may be lost, depleted, or otherwise inaccessible. Epinephrine has been used for more than a century as a bronchodilator and was historically administered subcutaneously or intramuscularly for acute asthma before selective β 2 -agonists became widely available. In emergency medicine, parenteral epinephrine remains an accepted rescue the …

30.08.2026journal-article

International Journal of Molecular Sciences

Natriuretic Peptides as Predictors for the Diagnosis of Pulmonary Hypertension Secondary to Left Heart Disease and for the Assessment of Its Severity

Filip Sawczak, Agata Kukfisz, Aleksandra Soloch, Kamila Kurkiewicz-Sawczak, Magdalena Dudek, Ewa Straburzyńska-Migaj, Marta Kałużna-Oleksy

Pulmonary hypertension (PH) frequently complicates heart failure with reduced ejection fraction (HFrEF) and worsens prognosis. Right heart catheterization (RHC) remains the diagnostic gold standard, but natriuretic peptides may help identify patients requiring invasive assessment. We retrospectively analyzed 563 HFrEF patients who underwent RHC. Patients with and without PH were compared. Associations between B-type natriuretic peptide (BNP), N-terminal pro-B-type natriuretic peptide (NT-proBNP) and RHC parameters …

30.08.2026journal-article

JAMA Internal Medicine

Specialist Referral for Cardiovascular Risk in Patients With Prostate Cancer

Darryl P. Leong, Celestia Higano, Cristina Cano Garcia, Vincent Fradet, D. Robert Siemens, Tamim Niazi, Bobby Shayegan, Avirup Guha, Filipe Cirne, Joseph B. Selvanayagam, Philippe D. Violette, Felipe H. Valle, Luke T. Lavallée, Emmanuelle Duceppe, Patrick Anderson, Denis Xavier, Jose Patricio Lopez-Lopez, Nicolas Villareal Trujillo, Ariel Galapo Kann, Rafaela K. Piccoli, Marina Mourtzakis, David Sarid, Srivatsa Narasimha, Patrick P.W. Luke, Ludhmila A. Hajjar, Himu Lukka, Laurence Klotz, Kumar Balasubramanian, Rajibul Mian, Steven Agapay, Sumathy Rangarajan, Sarah Karampatos, Kelvin K. H. Ng, Alvaro Avezum, P. J. Devereaux, Jehonathan H. Pinthus, RADICAL PC Investigators, Alanna Hall, Meghan Cagnin, Maheen Farooqi

Importance Patients with prostate cancer have a high burden of cardiovascular risk factors, often suboptimally controlled, and adverse cardiovascular outcomes. Objective To determine whether the routine referral of patients with prostate cancer to a cardiovascular specialist to implement a systematic risk factor strategy is more likely to reduce adverse cardiovascular outcomes and improve risk factor control than usual care. Design, Settings, and Participants This randomized clinical trial included patients with pr …

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30.08.2026journal-article

Arthroscopy

Editorial Commentary : Use of Glenoid Labral Augmentation as an Effective Treatment for Subcritical Glenoid Bone Loss

Anthony Zacharias

Abstract Restoration of joint function and mechanics is the goal of every shoulder stabilization surgery. Achieving this goal in the setting of altered anatomy and bone loss is easier said than done. In restoring a joint, it is important to understand what native tissue can be repaired, what can be augmented, or what needs to be reconstructed. For this, we rely on biomechanical research, patient outcomes, and long‐term follow‐up of patients. Bone augmentation procedures have provided a crucial role in shoulder inst …

30.08.2026journal-article

Journal of Clinical Medicine

Restoration of Radial Bowing After Elastic Stable Intramedullary Nailing in Pediatric Forearm Fractures: The Importance of Bowing Location in Addition to Magnitude

Osman Görkem Muratoğlu, Hasan Ceylan, Gökhan Güzel, Fatih Günaydın, Fevzi Mehmet Kuyumcu, Mehmet Ali Talmaç, Cem Yıldırım

Background/Objectives: Elastic stable intramedullary nailing (ESIN) is widely used for the treatment of pediatric diaphyseal forearm fractures. Although fracture union is commonly achieved, restoration of physiological radial bowing is essential for optimal forearm biomechanics. Most previous studies have focused on bowing magnitude, whereas the anatomical location of maximal radial bowing has received limited attention. Methods: This retrospective observational study included pediatric patients aged 4–16 years who …

30.08.2026journal-article

Revista ft

Detecção e diagnóstico de falhas em sistemas HVAC e sua relação com o desempenho energético de edificações: uma análise bibliométrica

Bruno de Oliveira Schneider, Guilherme Agues Emerick, Matheus Alves Lima, Rodrigo de Souza, Thales Rodrigues Barboza

Heating, ventilation, and air conditioning systems (HVAC) play an important role in the energy performance of buildings and faults in their components can compromise operational efficiency, increasing energy consumption. This study analyzed the scientific literature on fault detection and diagnosis (FDD) in HVAC systems and its relationship with building energy performance, seeking to understand the evolution of the topic and its main trends. A bibliometric analysis was conducted using publications indexed in the W …

30.08.2026journal-article

International Journal of Medical Sciences and Pharma Research

Implementing Enhanced Recovery After Surgery (ERAS) Protocols in Resource-Limited Environments: A Critical Review for Nigerian Surgical Patients

Fagbohun Omolola, Oshunpidan Adekunbi, Eke Ngozi

Background: Enhanced Recovery After Surgery (ERAS) protocols have been shown to improve perioperative outcomes and reduce healthcare costs in various settings. However, their implementation in resource-limited environments, such as Nigeria, remains constrained due to infrastructural, economic, and sociocultural barriers. Methods: This critical review synthesizes current literature on the application of ERAS protocols in resource-constrained environments, with a focus on Nigeria. A comprehensive search of PubMed, Sc …

30.08.2026journal-article

International Journal of Medical Science and Dental Health

Comorbidity Patterns Associated with Renal Dysfunction Across COPD Severity Stages and Clinical Phenotypes

Abdigaffar G. Gadaev, Muborak S. Salaeva, Dinora A. Parpibaeva, Nargiza D. Salimova, Fazilat R. Ismoilova, Abdisalim K. Kulkarayev

Background: Chronic obstructive pulmonary disease (COPD) is frequently accompanied by cardiovascular, metabolic, haematological and urinary system comorbidities. The presence of renal dysfunction may further modify the clinical profile and prognostic significance of these comorbid conditions. Objective: To comparatively evaluate comorbidities associated with renal dysfunction in patients with COPD across different disease severity stages and clinical phenotypes. Methods: A total of 609 patients with COPD were inclu …