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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.08.2026journal-article

Progress in Additive Manufacturing

Effect of aging temperature on the microstructure and tribological behavior of an 18Ni maraging steel manufactured by laser powder bed fusion (LPBF)

José Wilmar Calderon-Hernández, Fábio Faria Conde, Maryory Astrid Gómez Botero, Jorge Mauricio Sepúlveda Castaño, Alexander Zuleta Durango, Daniela Passarelo Moura da Fonseca, Julian Arnaldo Avila

Abstract This study addresses the critical knowledge gap regarding the influence of kinetically controlled austenite reversion on the tribological stability of Laser Powder Bed Fusion (LPBF) 18Ni-300 maraging steel. While conventional aging focuses on peak hardness (450–550 °C), this research investigates the high-temperature aging regime (610 °C and 650 °C) to elucidate the correlation between phase meta-stability and the evolution of protective tribo-layers. Samples were characterized using LOM, SEM, and XRD, wit …

03.08.2026journal-article

Journal of Community Medicine and Public Health Research

Impact of HIV/AIDS on Quality of Life in People Living with HIV (PHLV) and Their Caregivers’ – A Mix Method Study

Binal Prajapati, Parimal Gurjar, Krunal Modi, Dhiren Amin, Devanshi Jani

Antiretroviral therapy (ART) has changed the life expectancy of PLHIV patients, but not the quality of life (QoL). Caregivers of PLHIV are also facing social rejection, stigma, and many more problems, similar to those of PLHIV patients. The study was designed as a mixed-method study to document the Quality of life of HIV/AIDS Patients in a tertiary care hospital. The first aspect was the quantitative part, which included the World Health Organization Quality of Life Brief Version (WHO QoL BREF), which focused on th …

03.08.2026journal-article

Успехи геронтологии

ДИНАМИКА ГЕРИАТРИЧЕСКОГО СТАТУСА ПОЖИЛЫХ ПАЦИЕНТОВ В УСЛОВИЯХ ДЛИТЕЛЬНОЙ ГИПОМОБИЛЬНОСТИ В ПЕРИОД ПАНДЕМИИ COVID-19

А.С. Рукавишников, О.М. Кузьминов, С.Г. Горелик, Д.П. Пискунов

Пандемия COVID-19 и введённые в этот период ограничительные меры оказали существенное влияние на состояние здоровья лиц пожилого возраста. В этой связи особый интерес представляет оценка изменений гериатрического статуса, в частности перехода от состояния преастении к сформированному синдрому старческой астении, в условиях длительного ограничения двигательной активности и социальной изоляции. Цель исследования — анализ динамики гериатрического статуса пациентов пожилого возраста при продолжительном пребывании в усл …

03.08.2026journal-article

Global Journal of Education, Finance and Management

A Contextual Pastoral Approach in Strengthening the Ecological Awareness of the People

Agnes Monica, Silvester Adinuhgra, Yustinus Dwi Andriyanto

The ongoing ecological crisis has contributed to the emergence of human behavior that deviates from normative principles, while simultaneously shaping the lifestyles of society at large. Contextual pastoral care is understood as a form of faith accompaniment that stems from local social, cultural, and environmental conditions, not simply the uniform delivery of teachings without regard for the congregation's background. This study uses a qualitative method with a phenomenological paradigm to explore the experiences …

03.08.2026journal-article

Frontiers in Aging Neuroscience

Resting-state EEG microstate dynamics indicate altered brain network temporal organization in age-related hearing loss

Yurun Chen, Qiaoyu Liu, Yaohan Chen, Min Zhu, Yufei Qiao, Jiaran Chen, Wen Sun, Hua Yang, Yingying Shang

Objective Age-related hearing loss (ARHL) is increasingly recognized as a condition that involves changes in the central nervous system beyond the auditory pathway, with growing evidence showing altered large-scale brain network connectivity. However, how ARHL reshapes the temporal organization of large-scale brain networks remains poorly understood. This study aimed to investigate whether ARHL is associated with alterations in resting-state electroencephalogram (EEG) microstate dynamics and to examine the relation …

03.08.2026journal-article

Innovative Journal of Intelligent Control and Optimization for Electrical Systems

Monitoring of the Elderly with Dementia Based on Indoor Positioning System (IPS) Using Bluetooth Low Energy (BLE)

Annisa Sri Rahmi, Budhi Bakhitar, Reza Nandika, Muhammad Zaidan Addypa

Dementia is a neurodegenerative disorder that causes a decline in cognitive function in the elderly, increasing the risk of disorientation and loss in the indoor environment. This study aims to design and implement a monitoring system for the position and condition of elderly people with dementia based on Indoor Positioning System (IPS) using Bluetooth Low Energy (BLE) technology. The system was developed using five ESP32 modules consisting of three reference point devices, one mobile device worn by the elderly, an …

03.08.2026journal-article

International Journal of MS Care

Aging and Multiple Sclerosis: Multidisciplinary Care and Access to Care

Renee Stewart, Rachael Stacom, Jacquelyn Bainbridge, Patty Bobryk, Jeff Wilken, Jennifer S. Graves, Mona D. Bostick, Maureen T. Choman, John R. Corboy, Ruth Ann Marrie, Scott D. Newsome, Le H. Hua, Sarah A. Morrow, Yinan Zhang

Older adults with multiple sclerosis (MS) experience challenges across multiple aspects of health care, and health care delivery must evolve to meet the geriatric needs of the aging MS population. Although the literature on multidisciplinary care or access to care for older adults with MS is sparse, the geriatric care literature for the general population highlights the importance of comprehensive geriatric assessment and the barriers to health care. This review, based on a 2024 Consortium of MS Centers’ Consensus …

03.08.2026journal-article

Comparative Population Studies

The Long Shadow of Migration: How Mobility Biographies Shape Mental Health Among Older Adults in Europe

José David López Blanco

This paper examines how mobility biographies shape mental health in later life. Moving beyond the conventional migrant/non-migrant binary, we reconstruct complete internal, return, and international migration histories for individuals aged 50 and older across 20 European countries, linking retrospective life-history data from SHARE to repeated measures of depressive symptoms (Waves 4-9). Our results reveal three sets of findings. First, international migrants face a substantial and persistent mental health penalty, …

03.08.2026journal-article

Veredas do Direito

DRIVING FACTORS OF COMMERCIAL HEALTH INSURANCE PARTICIPATION INTENTION IN CHINA UNDER POPULATION AGING: DISTINCT EFFECTS OF INDIVIDUAL COGNITION AND RISK PERCEPTION

Xia Zhang, Chun-Shuo Chen

Against the backdrop of deepening population aging and rising demand for medical security in China, Service Quality (SQ)and Strong Tie (ST) are key factors in boosting the intention to purchase commercial health insurance. This study conducts empirical analysis to test research hypotheses based on 565 valid online samples. The findings indicate that both factors significantly increase Participation Intention (PI). Individual Cognition (IC) partially mediates their relationships, while Risk Perception (RP) exerts a …

03.08.2026journal-article

Frontiers in Nutrition

Sex-specific nutritional and inflammatory trajectories during first-line chemotherapy in older adults with advanced non-small cell lung cancer

Jinxian He, Mingjie Gu, Zhimei Chen, Jiahui Fu, Jian Yu

Background Malnutrition and systemic inflammation are closely interrelated determinants of treatment tolerance and prognosis in older adults with advanced non-small cell lung cancer. However, their sex-specific longitudinal patterns during chemotherapy remain insufficiently characterized. This study aimed to describe and compare sex-specific trajectories of nutritional status and systemic inflammation during first-line chemotherapy and to explore their longitudinal association from a clinical nutrition perspective. …

03.08.2026journal-article

Aging Clinical and Experimental Research

The prognostic value of frailty criteria in older adults: a systematic review and meta-analysis

Konstantinos Prokopidis, Francesco Saverio Ragusa, Roberta Bonica, Alessandro D’Aleo, Mathias Schlögl, Gustavo Duque, Mario Barbagallo, Nicola Veronese

Abstract Introduction Frailty, a prevalent geriatric syndrome, increases susceptibility to adverse outcomes like mortality, cardiovascular disease, and hospitalization. This study evaluated the Fried frailty phenotype and its components’ association with clinical outcomes, focusing on mortality. Methods We conducted a systematic review and meta-analysis of studies on individuals aged 50 or more from databases searched up to October 2024. Included studies assessed at least one frailty criterion (weakness, slowness, …

03.08.2026journal-article

Journal of Applied Toxicology

SARS‐CoV‐2 Spike Protein Exacerbates Endothelial Dysfunction and Promotes Lung Injury in Aging Type 2 Diabetes Mellitus Cell Culture Model

Nur Fatin Zalikha Zailan, Hui Yee Chee, Eusni Rahayu Mohd Tohit, Maha Abdullah, Syafinaz Amin Nordin, Irmi Zarina Ismail, Masriana Hassan

ABSTRACT Advanced age and diabetes mellitus (DM) are major risk factors for severe COVID‐19, associated with acute respiratory distress syndrome (ARDS), cytokine storm, and increased mortality. SARS‐CoV‐2 spike protein (SP) binding to angiotensin‐converting enzyme 2 (ACE2) potentially disrupts the renin–angiotensin system (RAS), promoting angiotensin II (Ang II) accumulation and vascular dysfunction. In individuals with preexisting endothelial dysfunction (ED), such as older adults with type 2 DM (T2DM), COVID‐19 m …

03.08.2026journal-article

Frontiers in Public Health

The pathway to establishing and implementing opioid agonist therapy (OAT) for people who inject drugs in Nairobi, Kenya

Emily Koech, Christopher Welsh, Mercy Karanja, Jebet Boit, Rebecca Wangusi, Patrick Awuor, Oscar Munyao, Tina Masai, Sam Wafula, Caroline Ngunu, Obwiri Kenyatta, Immaculate Mutisya, Jonathan Mwangi, Beatrice Gichuhi, Ansley Lyn, Kristen Stafford, Taylor Lascko, Geoffrey Ndichu, Caroline Ng'eno

Sub–Saharan Africa (SSA) is experiencing a burgeoning population of people who inject heroin. This has created an urgent need for the scale-up of comprehensive harm reduction services including medication for opioid use disorders. The rise in illicit drug use threatens the gains made in the fight against HIV in this high HIV burden region. People who inject drugs (PWID) have an increased risk of HIV acquisition and transmission due to factors such as needle sharing and engaging in high-risk sexual behaviors. Estima …

03.08.2026journal-article

Frontiers in Digital Health

Messenger-based chat counseling for young people in times of personal and global crises: evaluating the long-term feasibility of “krisenchat”

Juliane Hug, Elisabeth Kohls, Sabrina Baldofski, Jelena Scheider, Shadi Saee, Melanie Eckert, Richard Wundrack, Christine Rummel-Kluge

Background Adolescence is a critical period for the onset of mental health problems, a situation further exacerbated by recent global crises. This underscores the importance of low-threshold, anonymous online counseling services. Krisenchat , founded in Germany in 2020 following the COVID-19 outbreak, provides such support. While prior research has offered cross-sectional insights, little is known about changes in user characteristics and measures of the service's feasibility over time, especially regarding the cha …

03.08.2026journal-article

Public Health Nursing

Adaptation to Chronic Disease as a Mediator Between Health Literacy and Frailty in Older Adults: Implications for Public Health Nursing Practice

Gizem YağızÇelebioğlu, Melike Yalçın Gürsoy

ABSTRACT Objective To examine whether adaptation to chronic disease mediates the relationship between health literacy and frailty among older adults with chronic illnesses. Design A cross‐sectional design. Sample The study included 398 older adults aged 65 years and over attending routine outpatient visits at a public hospital in western Türkiye. Measurements Data were collected through face‐to‐face interviews using the Turkish Health Literacy Scale‐32 (THLS‐32), Adaptation to Chronic Disease Scale (ACDS), and FRAI …

03.08.2026journal-article

The FEBS Journal

A single‐nucleus chromatin accessibility atlas reveals epigenetic dynamics in aging mouse skeletal muscle

Juan An, Guangyao Lai, Jing Zuo, Jianwen Yuan, Lixin Fu, Bo Zhang, Xiao Zhang, Yuan Lv, Pengcheng Guo, Dajiang Qin, Miguel A. Esteban, Yancheng Song, Yiwei Lai

Skeletal muscle undergoes a progressive decline in mass and function with aging, a condition that in its extreme form is known as sarcopenia. This is driven by complex cellular and molecular alterations, such as shifts in myonucleus composition, increased fibrosis, and fat or immune cell infiltration. Despite extensive research, effective therapeutic interventions for sarcopenia remain limited. Recent advances in single‐cell omics technologies have begun to unravel the cellular and molecular heterogeneity of mouse …

03.08.2026journal-article

International Journal of Computer Information Systems and Industrial Management Applications

A Study on the Social Determinants of Falls among Elderly People in Chinese Communities from the Perspective of Urban-Rural Differences - Based on the CHARLS Data

Yanzhu Huang, Ananya Manit, Sumate Sathitbun-anan, Pasinpong Souppornsingh, Sirilak Jungrungrueng

Objective: To understand the current situation of falls among community-dwelling elderly in China and analyze the influencing factors. Methods: The study was conducted on respondents aged 60 and above in the 2020 China Health and Retirement Longitudinal Study (CHARLS). X2 test, t test, and logistic regression analysis were used to analyze the influencing factors of falls among the elderly. Results: A total of 10,837 respondents were included, with 53.51% being female. The incidence of falls among community-dwelling …

03.08.2026journal-article

Frontiers in Neuroscience

Reactive-accelerated-aging soak testing of thin-film polyimide layers treated with an oxygen plasma and chemical soaking

Kenneth A. Fluker, Jack W. Judy

Reliable bonding between polyimide layers is critical for the long-term performance of thin-film neural interfaces, yet the long-term durability of common adhesion methods under physiologically relevant conditions remains unclear. This study uses reactive-accelerated-aging (RAA) soak testing at 87°C to compare the ability of surface treatments based on oxygen plasma and KOH/HCl soaks to enhance polyimide-to-polyimide adhesion. Peel testing was performed as a function of soak time and strip width to quantify degrada …

03.08.2026journal-article

Archives of Rheumatology

Cognitive Impairment Risk in Middle-Aged and Older Adults with Rheumatoid Arthritis: Development and Validation of a China Health and Retirement Longitudinal Study–Based Prediction Model

Xiaomeng He, Guoqing An, Shuyong Zhang, Yinggang Su, Xindi Kang, Xuying Liu, Xuan Qi

Background/Aims: Cognitive impairment is frequent in rheumatoid arthritis (RA) and worsens function and quality of life; yet, simple tools to identify high-risk community-dwelling patients are scarce in China. This study aimed to develop and test a practical tool to predict cognitive impairment risk in adults with RA. Materials and Methods: A cross-sectional analysis was performed using the China Health and Retirement Longitudinal Study (CHARLS) database for participants aged ≥45 years with self-reported physician- …

03.08.2026journal-article

Scientific Data

AMYPAD-PNHS: A Pan-European, Multi-Site & Multimodal MRI Dataset of Older Adults Without Dementia

Leonard Pieperhoff, Mario Tranfa, Prithvi Arunachalam, Carole H. Sudre, Mathijs B. J. Dijsselhof, Beatriz Esteves Padrela, Federico Masserini, Stefano Caneva, Giuseppe Pontillo, David M. Cash, Emma S. Luckett, Craig Ritchie, Mercè Boada, Marta Marquié, Wiesje M. van der Flier, Rik Vandenberghe, Lisa Quenon, Bernard J. Hanseeuw, Pablo Martinez-Lage, Pierre Payoux, Anouk den Braber, Pieter Jelle Visser, Michael Schöll, Giovanni B. Frisoni, Andrew W. Stephens, Frank Jessen, Juan Domingo Gispert, Henk-Jan M. M. Mutsaerts, Alle Meije Wink, Lyduine E. Collij, Luigi Lorenzini, Frederik Barkhof

Abstract The Amyloid Imaging to Prevent Alzheimer’s Disease Prognostic and Natural History Study (AMYPAD-PNHS) multimodal magnetic resonance imaging (MRI) dataset provides open-access longitudinal MRI data of 2759 cognitively normal or mild cognitive impairment individuals, encompassing (micro-)structural, physiological, and functional MRI sequences from 10 European parent cohorts. Processed and raw images, and image-derived (endo-)phenotypes, are organized in Brain Imaging Data Structure (BIDS) standards and acces …

03.08.2026journal-article

Western Journal of Nursing Research

Family Caregivers of Patients with Dementia in Primary Care: Assessment of the Psychosomatic Dimensions of Caregiver Burden

Ioanna Dimitriadou, Charoula Mesira, Aikaterini Toska, Evangelos C. Fradelos, Theodosios Paralikas, Foteini Malli, Pavlos Sarafis, Maria Saridi

Background: Dementia represents a growing global public health challenge, with increasing reliance on informal family caregivers to support individuals living with the condition. Caregiving responsibilities may affect caregivers’ psychological well-being, resilience, and overall quality of life (QoL). Purpose: This study aimed to examine caregiver burden, resilience, and QoL among family caregivers of people with dementia in primary care settings and to explore the association of these outcomes with key sociodemogr …

03.08.2026journal-article

Journal of Clinical and Basic Psychosomatics

Effects of multisensory environmental stimulation interventions using virtual reality therapy in patients with dementia and comorbid conditions

Ziwei Zhou, Zhuqing Wang, Xinying Zhou, Qingfeng Xie, Yun Chen, Pei Li

As the incidence of dementia rises annually, the demand for cognitive intervention in dementia patients with comorbid underlying diseases has become increasingly urgent. However, most existing studies focus on single-modal interventions, and there remains a gap in exploring the composite intervention model of virtual reality (VR) technology combined with multisensory stimulation and its core effect mechanism. This study aims to investigate the effects of a multisensory environmental stimulation intervention using V …

03.08.2026journal-article

Journal of Imaging

Small-Data Deep Learning for Alzheimer-Spectrum Classification from Structural MRI: A Feasibility Study Using OASIS

Ian D. Li, Choong-Yong Ung, Cristina Correia

Accurate estimation of Alzheimer’s disease (AD) severity from structural magnetic resonance imaging (MRI) remains difficult, as disease-associated anatomical alterations are often subtle and publicly available datasets are typically too small to support robust deep learning model training. This feasibility study sought to determine how much Alzheimer’s disease spectrum-related information could be extracted from a small structural MRI cohort using a deliberately lightweight two-dimensional convolutional neural netw …

03.08.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

TELEATENDIMENTO NA ATENÇÃO PRIMÁRIA À SAÚDE NO CUIDADO ÀS PESSOAS COM DOENÇAS CRÔNICAS NÃO TRANSMISSÍVEIS: RELATO DE EXPERIÊNCIA

Amanda Nichele, Henrique Resin, Isadora Petry, EduardaEduarda Pufal, Laura Bosi Gil, Franciele Rissi dos Reis, Jéssica Damian, Joyce Premoli Soares, Patrícia Cilene Freitas Sant’ Anna, Márcia Rejane Strapasson

Objetivo: Relatar a experiência de teleatendimento em saúde de demandas relacionadas a doenças crônicas em adultos e idosos na rede de atenção à saúde do município de São Leopoldo/RS. Método: Trata-se de um relato de experiência em teleatendimento a pacientes com doenças crônicas, na perspectiva interdisciplinar em saúde. Resultados: A experiência relatada permitiu dar visibilidade ao programa de telessaúde, por meio do teleatendimento a usuários com demandas de doenças crônicas no município em estudo, que teve ori …