Frag' FlorenceEvidenz. Klar. Anwendbar.
Uhr 7/8Sources Journal Tree
Easy Demo

Florence Themenbrowser · Medizin · Seite 122

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
30.08.2026journal-article

Farabi Tıp Dergisi

Evaluation of Helicobacter pylori Stool Antigen Test Results According to Demographic and Clinical Characteristics of Patients

Mustafa Erdem Sarp, Serranur Altun Sarp, Mediha Uğur, Özkan Bahadir

Objective: This study aimed to evaluate Helicobacter pylori (H. pylori) antigen test results in stool samples in relation to the epidemiological features of patients.Material and Methods: This retrospective study included patients who underwent H. pylori antigen testing between 2022 and 2024. Analyses were performed using the H. pylori antigen test kit produced by RDS Laboratory Systems (Ankara, Türkiye). Demographic and clinical data were obtained from the hospital information system. Positivity rates were evaluat …

30.08.2026journal-article

Archiv Euromedica

THE ROLE OF DIET AND LIFESTYLE IN THE TREATMENT OF ATTENTION DEFICIT HYPERACTIVITY DISORDER: A NARRATIVE REVIEW

Aleksandra Katarzyna Kłosowicz, Aleksandra Olga Pakulska, Natalia Rządzińska, Aleksandra Maria Błoch, Maria Anna Miller, Kornelia Julia Fimiarz, Aleksandra Jolanta Kamińska

Background Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by impaired concentration, impulsivity, and excessive motor activity. Although conventional therapy is effective in many patients, it may be associated with high costs, adverse effects, and incomplete symptom control. Therefore, complementary methods, such as dietary modifications and lifestyle factors, are gaining increasing importance in the management of ADHD. Aims The aim of this narrative review was to cri …

30.08.2026journal-article

Laryngoscope Investigative Otolaryngology

Airway Anatomy as a Predictor of Tracheostomy in Critically Ill Patients: A Multicampus Analysis of Airway Grade, Admission Diagnosis, and Clinical Trajectory

Michael Sramek, Dana Eitan, Darby Keirns, Bryant Noss, Hannah Gibbs, Austin R. Swisher, India Casaday, Payam Entezami

ABSTRACT Objective Determine whether the Cormack–Lehane airway grade at intubation predicts subsequent tracheostomy in critically ill adults and whether this association persists after controlling for admission diagnosis. Methods Retrospective multicenter cohort study of 10,234 ICU patients requiring ventilation across three campuses from April 2018 to June 2024. The primary predictor was Cormack–Lehane grade (1–4) during intubation; the primary outcome was tracheostomy. Principal problem documentation classified p …

30.08.2026journal-article

International Journal of Human and Health Sciences (IJHHS)

Assessment of Serum Vitamin D Levels among Patients Attending Institute of Nuclear Medicine and Allied Sciences (INMAS), Sylhet, Bangladesh

Kamrun Nahar, Muhammad Sirazul Munir

Deficiency of vitamin D is a major health problem globally and is associated with different chronic diseases. The aim of this study was to assess serum vitamin D levels according to age and gender at the Institute of Nuclear Medicine and Allied Sciences (INMAS), Sylhet, Bangladesh. A total 173 patients attending INMAS, Sylhet, for serum vitamin D levels evaluation from July 2022 to June 2023 were included in the study. Patients with vitamin D replacement therapy were excluded from this study. Serum viamin D was det …

30.08.2026journal-article

International Journal of Computer Science and Mobile Computing

Risk-Oriented Analysis and Classification of Network Attacks Affecting Hospital Information Systems: Evidence from a Patient-Monitoring Testbed

Crimary C. Mahinay, John Augustus P. Diesto, Jerald B. Babor, Ray Marlou T. Georpe, Welquim B. Panogaling, Serafin C. Palmares, Kristine T. Soberano

Hospital Information Systems increasingly rely on connected patient-monitoring devices that transmit biometric data through hospital networks. This study analyzed the WUSTL-EHMS-2020 testbed and assessed the potential risk of its recorded attacks to HIS. A quantitative descriptive secondary analysis retained all 16,318 verified records. Record-level summaries described Normal, Spoofing, and Data Alteration traffic; the primary comparison aggregated ordered records into 169 contiguous binary-label blocks (85 Normal …

30.08.2026journal-article

Journal of Clinical Medicine

Innovative Clinical Pathways for Pregnant Women with Obesity: The Padua Project (Northeastern Italy)

Maria Grazia Dalfrà, Giovanni Sartore, Eugenio Ragazzi, Silvia Burlina, Silvia Visentin, Silvia Pastrolin, Marco Tosi, Erich Cosmi, Annunziata Lapolla

Background/Objectives: Maternal obesity is associated with an increased risk of adverse maternal and neonatal outcomes. This study evaluated whether participation in a multidisciplinary antenatal care pathway improved pregnancy outcomes compared with routine clinical practice in women with pre-pregnancy obesity. Methods: 711 women of reproductive age with preconception body mass index (BMI) ≥ 30 kg/m2 were identified from medical records collected between 2010 and 2023: 233 women were managed according to the multi …

30.08.2026journal-article

Journal of Clinical Medicine

Association of PI-RADS Score with Clinically Significant Prostate Cancer and Histopathological Upgrading in Patients Undergoing Radical Prostatectomy: A Retrospective Single-Centre Study

Hubert Andrzej Krzepkowski, Tomasz Ząbkowski, Andrzej Wieczorek, Maciej Walędziak, Tomasz Waldemar Kamiński, Hubert Dąbrowski, Tomasz Syryło

Background and Objectives: Multiparametric magnetic resonance imaging (mpMRI) is widely used in prostate cancer diagnosis, but biopsy findings may still underestimate tumor aggressiveness. This study evaluated the association of Prostate Imaging Reporting and Data System (PI-RADS) assessment with clinically significant prostate cancer (csPCa) and histopathological upgrading after radical prostatectomy. Methods: The retrospective analysis comprised 564 patients who underwent mpMRI–transrectal ultrasound fusion-guide …

30.08.2026journal-article

International Journal of Stroke

Clinical Outcomes among Patients with Active Cancer and Acute Ischemic Stroke Treated with Antiplatelet versus Anticoagulant Therapy.

Gianluca Costamagna, Andreas Hottinger, Francoise Livio, Babak Benjamin Navi, Davide Strambo, Patrik Michel

Background: Patients with acute ischemic stroke (AIS) and active cancer (AC) face high risks of recurrent stroke and death. Evidence guiding antithrombotic selection remains limited. Aims: To investigate post-AIS prescribing patterns of antiplatelet versus anticoagulant therapy in AIS patients with AC and their associated clinical characteristics and outcomes. Methods: We retrospectively analyzed 2003–2024 data from the Acute-Stroke-Registry-and-Analysis-of-Lausanne (ASTRAL). We included patients with AC discharged …

30.08.2026journal-article

Sensors

Development and Clinical Evaluation of a Wearable 12-Lead Electrocardiographic Platform with Automated ECG Analysis for Telemedicine Applications

Zhadyra Alimbayeva, Chingiz Alimbayev, Kassymbek Ozhikenov, Kairat Karibayev, Aiman Ozhikenova, Kymbat Khaidarova, Madiyar Daniyalov, Ussen Shylmyrza, Yerbolat Igembay, Akzhol Nurdanali

Wearable electrocardiographic technologies have become increasingly important for continuous cardiac monitoring; however, most existing portable systems are limited by the number of recorded leads or provide only basic signal acquisition without advanced automated analysis. This study presents a third-generation wearable twelve-lead electrocardiographic platform developed for multilead ECG acquisition and automated spatial ECG analysis. Compared with the previous generation, the hardware modification primarily cons …

30.08.2026journal-article

Caucasian Medical Journal

Development and Internal Validation of a Clinical–Infectious Prediction Model Incorporating the Serum Pepsinogen I/II Ratio to Identify Histologically Confirmed Gastric Atrophy

Nursultan Kerimkulov, Bayan Nurgaliyeva

Background: Histologically confirmed gastric atrophy is a key precursor lesion in the intestinal pathway of gastric carcinogenesis. Serum pepsinogen I/II ratio (PGR) is a biologically plausible non-invasive marker of oxyntic gland loss, but its diagnostic performance varies across populations, assays, and clinical settings. Contemporary risk stratification increasingly favors multivariable prediction models over isolated biomarkers.Objective: To evaluate the association between serum PGR and histologically confirme …

30.08.2026journal-article

Frontiers on Healthcare Research

The Relationship Between the Jakarta Cardiovascular Score and Physical Activity: Screening of Cardiovascular Risk Factors in Older Adults

Department of Cardiology and Vascular Medicine, Dr. M. Djamil General Hospital, Padang, Indonesia, Citra Kiki Krevani Citra, Restu Restu Restu, Wahyudi Firmana Wahyudi, Rusdy Kamal Rusdy, Fikri Satria Fikri, Jolatuvel Bahana Jolatuvel, Najmi Ilal Hayati Najmi Ilal, Hajar Nurfa Jirin Hajar Nurfa

<p style="font-weight: 400;"><strong>Background:</strong> Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality worldwide, including in Indonesia, where low physical activity is a major modifiable risk factor. The Jakarta Cardiovascular Score (JAKVAS) was developed as a local modification of the Framingham Risk Score to better represent Indonesian populations by including physical activity as a variable. However, the quantitative relationship between physical activity level and JAKVAS has …

30.08.2026journal-article

International Journal of Pharmaceutical Sciences and Medicine

Quality by Design: Development of the Quality Target Product Profile (QTPP), Critical Quality Attributes (CQAs), Critical Material Attributes (CMAs) and Critical Process Parameters (CPPs) for Transdermal Drug Delivery Systems

C. Pandian, Praveen Kumar D, Gowtham A, Pooja B, Gunaseelan M, Keerthana M

The quality by design (QbD) paradigm has been the accepted model for building quality into pharmaceutical products rather than testing it in retrospectively. The systematic application of QbD to transdermal pharmaceutical delivery systems (TDDS) is relatively underdeveloped in the literature despite the growing commercial and clinical relevance of the dosage form, although QbD has been widely articulated for oral solid dosage forms and more recently for semisolid topical products. Transdermal patches present a diff …

30.08.2026journal-article

Psychoactives

Psilocybin-Assisted Therapy for Alcohol Use Disorder: A Systematic Review of Clinical Evidence

Laura Schäffert, Human-Friedrich Unterrainer

Background: Alcohol use disorder (AUD) remains a leading contributor to global morbidity, yet conventional treatments often yield suboptimal outcomes and high relapse rates. Psilocybin-assisted therapy has re-emerged as a potential intervention for substance use disorders, but its effectiveness and safety in AUD specifically remain to be comprehensively evaluated. Objective: To review and synthesize available evidence on the efficacy and safety of psilocybin-assisted therapy in adults with AUD. Methods: A systemati …

30.08.2026journal-article

International Journal of Computer Information Systems and Industrial Management Applications

Federated Self-Supervised Learning for Privacy-Preserving Clinical Diagnostics in Distributed Healthcare Systems

Abinaya V., S. Swathi, G. Sharmila, S. Karpaga Iswarya, P. Priyadharsini, Harini A.

The increasing adoption of distributed digital healthcare systems has enabled collaborative artificial intelligence (AI)-based clinical diagnostics across hospitals and medical institutions. However, conventional centralized learning requires sensitive patient information to be transferred to a common server, introducing substantial concerns regarding data privacy, security, institutional governance, and regulatory compliance. Furthermore, obtaining sufficiently large and accurately annotated clinical datasets rema …

30.08.2026journal-article

Psychiatry and Clinical Neurosciences

Blood Neurofilament Light Chain as a Biomarker of Central Network Dysregulation in Methamphetamine Use Disorder: A Multi‐Modal Investigation with Clinical Implications

Shyh‐Yuh Wei, Yu‐Li Liu, Huai‐Hsuan Tseng, Po See Chen, Yen Kuang Yang, Yihong Yang, Tzu‐Yun Wang

Aim There is a critical need for objective biomarkers that can link peripheral assays to central neural network dysfunction. We investigated blood neurofilament light chain (NfL), a marker of axonal injury, and C‐reactive protein (CRP), a marker of systemic inflammation, in relation to the brain network topology and microstructural integrity in methamphetamine use disorder (MUD), a paradigm of acquired neurotoxicity. Methods Forty‐two male MUD patients and 44 male controls received diffusion and resting‐state funct …

30.08.2026journal-article

Magnetic Resonance in Medicine

Ex Vivo Measurement of Human Blood T 1 at 5 T : Dependence on Hematocrit and Oxygenation

Shuwan Yu, Yuan Dong, Yuxiao Gu, Ne Yang, Lele Ma, Qingyu Xu, Ping Ma, Baoxin Zhou, Shuo Chen, Yonglin Chen, Dengrong Jiang, Xihai Zhao, Zixuan Lin

ABSTRACT Purpose To determine human blood longitudinal relaxation time (T 1 ) ex vivo at 5 T using modified Look‐Locker inversion recovery (MOLLI), and to evaluate its dependence on hematocrit (Hct) and oxygenation ( Y ). Methods A MOLLI 5(3)3 protocol was simulated across T 1 values of 1000–3000 ms to optimize the sampling interval. Aqueous gadolinium phantoms were scanned using optimized MOLLI and multi‐inversion‐time recovery spin echo (IR‐SE) acquisitions to derive a calibration equation. Arm venous blood from …

30.08.2026journal-article

International Journal of Pharmaceutical Sciences and Medicine

Recent Advances in Mouth Dissolving Films: Formulation Strategies, Evaluation and Therapeutic Applications

C. Pandian, Gowtham A, Gunaseelan M, Pooja B, Praveen Kumar D, Keerthana M, Dhanusiya V

Mouth dissolving films (MDFs) or oral dissolving films, are a novel and convenient method for drug delivery. They become even more useful by enhancing patient compliance and instant release of the drug. When thin and flexible polymer films come in contact with saliva, they break apart and release the drug without the aid of water. MDFs are particularly beneficial for patients who cannot swallow traditional dose forms, such as bedridden patients, those suffering from dysphagia, the elderly and children1. The product …

30.08.2026journal-article

Clinical Infectious Diseases

Should valve leaflet thickening be considered a characteristic lesion of infective endocarditis?

Georgios Tzimas, Pierre Monney, Nicoleta Ianculescu, Panagiotis Antiochos, Benoit Guery, Lars Niclauss, Matthias Kirsch, Matthaios Papadimitriou-Olivgeris

Abstract Background Valve leaflet thickening was recently incorporated into the 2023 version of the Duke criteria by the European Society of Cardiology (ESC) as a potential imaging marker of infective endocarditis (IE). The study aimed to assess the impact of valve leaflet thickening on the diagnosis of IE among patients investigated for suspected IE. Methods This retrospective study included adults with suspected IE at Lausanne University Hospital (2014-2025). IE was diagnosed by the 2023 Duke-ISCVID based on the …

30.08.2026journal-article

Clinical Medicine (Russian Journal)

Modern scientific concepts of Zika fever

Viktor L. Melnikov, Larisa N. Aftaeva, Anastasia V. Sergeeva, Daria S. Bezmenova, Olesya S. Lebedeva

The review article presents epidemiological, etiopathogenetic, clinical, and diagnostic aspects of Zika fever, as well as possible measures for the prevention and treatment of this infectious disease. The Zika virus (ZIKA) is transmitted through various routes, including vector-borne, vertical, sexual, and hemato-transfusion, which determines the clinical presentation of patients, the high rate of fetal death, and the development of severe congenital malformations. Currently, there is no specific etiotropic therapy …

30.08.2026journal-article

Interdisciplinary Medicine

3D printing of cell‐free implants: A promising avenue for cartilage regeneration and joint preservation

Liangbin Zhou, Shangsi Chen, Boguang Yang, Yiting Lei, Hegeng Li, Haoyue Luo, Xiaoshuai Wang, Qiongjiao Zeng, Jiahui Lai, Fei Jin, Rocky S. Tuan, Zhong Alan Li

Abstract Cartilage regeneration and joint preservation are confronted with tremendous challenges. Traditional cell‐based treatments, while effective in some cases, still encounter many limitations, including immunogenicity, high costs, and logistical problems concerning cell sourcing, in vitro expansion, and storage. Recent progress in 3D printing technologies offers a promising alternative: 3D‐printed cell‐free implants. By exploiting biomaterial‐driven activation and augmentation of the pro‐regenerative roles of …

30.08.2026journal-article

Journal of Clinical Medicine

Renal Cell Carcinoma in the Geriatric Population: Toward a Frailty-Adapted Therapeutic Paradigm

Cemile Ozsurekci, Ufuk Yazar, Yusuf Acikgoz

Background: Renal Cell Carcinoma (RCC) primarily affects older adults, with incidence increasing with age. Older adults remain underrepresented in clinical trials, and treatment decisions are often extrapolated from younger populations. Age-related factors such as comorbidities, frailty, polypharmacy, and immunosenescence complicate management in the geriatric population. Methods: A narrative review of the literature was conducted, focusing on localized and metastatic RCC in older adults. The review comprehensively …

30.08.2026journal-article

Journal of Asian Medical Students' Association

Efficacy of Complementary Nutritional and Herbal Interventions on Peripheral Inflammatory Biomarkers and Clinical Outcomes in Parkinson’s Disease: A Systematic Review

Putu Ayu Anindita Maheswari Kusumaningtyas Nugraha Budha, Nicky Stevani Wijaya, Marcella Marcella, Alicia Priscila Estelle, Joyceline Chika Tanely

Background: Dopaminergic neuron loss, neuroinflammation, oxidative stress, and disruption of the gut microbiota are all linked to Parkinson's disease, a progressive neurodegenerative condition. Probiotics and synbiotics are examples of non-pharmacological adjuvant treatments that have shown potential advantages through modulation of neurotrophic and inflammatory pathways, while results are still mixed. Purpose of Study: The purpose of this systematic review was to evaluate the impact of non-pharmacological adjuvant …

30.08.2026journal-article

Frontiers on Healthcare Research

A Little of Everything, Just In Time: Multimodal Opioid-Sparing Anesthesia for a Twin Pregnancy in Decompensated Heart Failure Caused by Severe Mitral Stenosis

Department of Anesthesiology and Intensive Therapy, Faculty of Medicine Universitas Indonesia – Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Muhammad Imam Mulia Muhammad Imam, Department of Anesthesiology and Intensive Therapy, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia, Arief Cahyadi Arief

<p style="font-weight: 400;"><strong>Background: </strong>Rheumatic heart disease remains a leading cause of valvular heart disease among women of reproductive age in low- and middle-income countries. Severe mitral stenosis complicating pregnancy substantially increases the risk of acute cardiac decompensation because of the hemodynamic load imposed by gestation, and anesthetic management becomes considerably more complex when it is combined with atrial fibrillation with a rapid ventricular response and a multifeta …

30.08.2026journal-article

IECCMEXICO

Beyond Preoperative Clearance: Integrated Cardiovascular Surveillance and Multiorgan Protection in Major Noncardiac Surgery

Daniel Fernando Camargo Medina, Beverly Denisse Jaramillo Jaramillo, Daniel Fernando Trejos Gartner, Dominique Magdalena Nathan Kreisberg, Ana Carla Naranjo González, Vicente Treviño Caballero, Justin Santiago Palacios Moreira, Diego Clemente Moreno

Perioperative cardiovascular complications remain an important cause of morbidity and mortality after major noncardiac surgery. This integrative review analyzed international evidence on cardiovascular event prediction, physiological and biochemical monitoring, and multiorgan-protection strategies, with particular attention to their applicability in Latin America. Twenty central publications were selected from PubMed/MEDLINE, Scopus, SciELO, LILACS, the Cochrane Library, and international guideline repositories. Th …