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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

Frontiers in Neurology

“Internal carotid artery-type cervical spondylosis” is not supported as an independent subtype: a perspective on diagnostic classification and clinical differentiation

Tianjun Zhai, Yeping Chen, Wei Feng, Hui Zhang

Cervical spondylosis is a common degenerative disorder, yet its diagnostic boundaries may be inappropriately expanded when nonspecific symptoms such as dizziness coexist with age-related cervical imaging changes. This Perspective evaluates the hypothetical concept of “internal carotid artery-type cervical spondylosis” and whether it qualifies as an independent clinical subtype. Using an adapted validity–utility framework, the proposed entity was assessed according to five criteria: a specific anatomical relationshi …

27.08.2026journal-article

Frontiers in Public Health

Which exercise strategies improve postpartum depression? A systematic review and meta-analysis of randomized controlled trials

Jun-Jun Qiao, Jing-Tong Zhang, Zheng Zhang, Jin-Peng Wang, Xin Liu

Objective Postpartum depression adversely affects both mothers and infants and remains an important issue in maternal health. This meta-analysis examined the overall effects of exercise interventions on postpartum depressive symptoms and explored whether programme characteristics influenced treatment outcomes. Methods A systematic search of major databases was conducted to identify randomized controlled trials evaluating exercise interventions for postpartum depression. Sixteen studies met the inclusion criteria. P …

27.08.2026journal-article

Clinical Journal of Health Sciences

The Mediating Role of Rumination in the Relationship Between University Students' Attachment Dimensions and Future Anxiety

İlayda Üçer, Manolya Çalışır

The purpose of this study is to examine the mediating role of ruminative thought processes in the relationship between attachment dimensions and future anxiety among college students. To this end, 420 participants were included in the study. Participants completed the Sociodemographic Information Form, the Experiences in Close Relationships Inventory II, the Rumination Response Scale, and the Future Anxiety Scale for College Students online. According to the study results, there are positive correlations between th …

27.08.2026journal-article

Symmetry

PNS-WINGS-AHP–EWM Integrated Framework for Multi-Criteria Decision Analysis: An Application-Oriented Decision Framework in Digital Agriculture

Yawen Wang, Kecheng Zhang

Digital-agriculture development increasingly requires multi-criteria decision analysis (MCDA) approaches to evaluate complex and interrelated influencing factors. However, existing methods often face difficulties in representing uncertain expert judgments, capturing inter-factor influence structures, and integrating complementary weighting information. To address these challenges, this study develops an integrated Pythagorean Neutrosophic Sets (PNS)–Weighted Influence Non-linear Gauge System (WINGS)–Analytic Hierar …

27.08.2026journal-article

Information

Education Informatics as a Discipline for Equitable, Evidence-Informed and Sovereign Digital Education Systems: A Critical Conceptual Review

Hannes Tegelbeckers, Frank Bünning

Education systems are increasingly shaped by decisions about infrastructure, interoperability, data governance, procurement, and artificial intelligence, yet no established field treats these decisions as a single object of professional responsibility. This article asks whether Education Informatics can be specified as a distinct interface discipline, analogous to Business Informatics and Engineering Informatics. It is a critical conceptual review addressing four review questions; its search is documented using the …

27.08.2026journal-article

Wellcome Open Research

The chromosomal genome sequence of a staghorn coral, Acropora cf. manni (Scleractinia: Acroporidae)

David J Combosch, Andrew H Baird, David R Burdick, Hector Torrado, Dareon Rios, Sebastian Metz, Michael Sweet, Graeme Oatley, Elizabeth Sinclair, Eerik Aunin, Noah Gettle, Camilla Santos, Michael Paulini, Haoyu Niu, Victoria McKenna, Rebecca O’Brien, Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team, Wellcome Sanger Institute Scientific Operations: Sequencing Operations, Wellcome Sanger Institute Tree of Life Core Informatics team, EBI Aquatic Symbiosis Genomics Data Portal Team, Aquatic Symbiosis Genomics Project Leadership

We present a genome assembly from a colony sample of Acropora cf. manni (staghorn coral; Cnidaria; Anthozoa; Scleractinia; Acroporidae). The assembly contains two haplotypes with total lengths of 459.26 megabases and 489.30 megabases. Most of haplotype 1 (94.39%) is scaffolded into 14 chromosomal pseudomolecules. Haplotype 2 was assembled to scaffold level. The mitochondrial genome has also been assembled, with a length of 18.48 kilobases. Metagenome binning recovered one bacterial bin from the phylum Chlamydiota.

27.08.2026journal-article

Veterinary Medicine and Science

Clinical Case and Follow‐Up of Babesia banethi Infection in a Red Fox

Mariaelisa Carbonara, Michela Prioletti, Antonio Camarda, Stefano Castellana, Giuseppe Menga, Giovanna Girardi, Gad Baneth, Domenico Otranto

ABSTRACT Background Red foxes play an important role in the circulation of ticks and tick‐borne pathogens, including Babesia spp. While for Babesia vulpes many studies are available on its epidemiology in fox populations as well as pathogenicity in dogs, no data are reported for the recently described Babesia banethi infecting red foxes. Objective Here we describe the clinical and parasitological follow‐up of a naturally occurring B. banethi infection in a red fox from southern Italy. Case presentation An adult mal …

27.08.2026journal-article

Journal of Clinical Medicine

Initial Clinical Experience with Percutaneous Endocardial Septal Pulsed Field Ablation in Hypertrophic Obstructive Cardiomyopathy: A First-in-Human Case Series

Haoruo Zhang, Yanfeng Tian, Songqing Yang, Rui Cao, Haoran Jing, Chunlin Gong, Jiaoyue Zhong, Yuran Chen, Siting Hong, Zhaojun Wang

Background: Pulsed field ablation is a nonthermal ablation modality with a potentially favorable tissue selectivity profile. However, its application in septal reduction therapy for hypertrophic obstructive cardiomyopathy remains unexplored clinically. We investigated the feasibility and short-term outcomes of percutaneous endocardial septal pulsed field ablation in patients with symptomatic hypertrophic obstructive cardiomyopathy. Methods: Five patients with symptomatic hypertrophic obstructive cardiomyopathy and …

27.08.2026journal-article

Clinical Journal of Health Sciences

The Role of Anima-Animus Balance in Relationships and Its Psychopathological Reflections: A Review within the Framework of Analytical and Clinical Psychology

Gamze Küçükaslan, Reşat Güven, Buse Odabaşı, Deniz Ergün

This study is a systematic review examining the role of anima and animus archetypes in the spiritual integration processes of individuals, their effects on interpersonal relationships, and their psychopathological manifestations within the framework of Carl Gustav Jung’s analytical psychology theory. Anima and animus are defined as opposite-sex archetypes located in the unconscious of the individual and play a decisive role in the individuation process. In this context, the effects of anima and animus on the indivi …

27.08.2026journal-article

Wellcome Open Research

Sleep CHAMPzzz: Sleep and Circadian Health in Adolescents - a Mental-health Participation Study (protocol)

Gosia Lipinska, Laura C. Roden, Jonathan Davy, Karine Scheuermaier, F. Xavier Gómez-Olivé, Raphaella Lewis, Swantje Wells, Ksenija Maravic da Silva, Yvonne M. Milton, Erika Abric, Fiona Belford, Anita E.M. Lee, Ben A. Carew, Niela van der Poll, Teagan L.Y. Niemand, Noel Reddy, Kirstin Davies, Morgan Naidoo, Tilly Weston, Dale E. Rae

Background Adolescence is characterised by changes in brain development, sleep and circadian biology. Sleep and circadian processes are important modulators of depression and anxiety, which can increase mental health difficulties, and often progress to chronic disorders in adulthood. This study aims to identify sleep and circadian-related mechanisms through which adolescents may either develop or demonstrate resilience to depression and anxiety. Methods SleepCHAMPzzz (Sleep and Circadian Health in Adolescents - a M …

27.08.2026journal-article

Medical Sciences

Clinical Remission Trajectories Beyond 12 Months in Severe Asthma Patients Continuing a Single Biologic: A Real-World Single SANI Center Cohort

Simone Negrini, Stefania Nicola, Francesco Sardanapoli, Rocco Francesco Rinaldo, Marco Russo, Iuliana Badiu, Anna Quinternetto, Luca Lo Sardo, Francesco Blasi, Pierluigi Paggiaro, Enrico Heffler, Giovanni Rolla, Caterina Bucca, Giorgio Walter Canonica, Fulvia Ribolla, Paolo Solidoro, Luisa Brussino

Background: Clinical remission is an emerging therapeutic goal in severe asthma treated with biologics. However, remission may evolve beyond the conventional 12-month assessment, and limited real-world data are available on patients who continue the same biologic after incomplete remission at 12 months. We evaluated longitudinal remission trajectories in patients with severe T2-high asthma continuing the same biologic therapy. Methods: This retrospective real-world single-center SANI cohort included adults with sev …

27.08.2026journal-article

Archiv Euromedica

SOCIAL MEDIA AND MENTAL HEALTH SELF-DIAGNOSIS: RISKS, BENEFITS, AND CLINICAL IMPLICATIONS FOR ADOLESCENTS AND YOUNG PEOPLE

Bogna Błachowska, Wojciech Frączyk, Agata Świątek, Kamil Andruszkiewicz, Bartosz Machnio, Natalia Jasińska, Mateusz Krysiak, Natalia Turzyńska, Katarzyna Mania, Julia Bąk, Agnieszka Stankowska

Background Adolescents increasingly use social media platforms, including TikTok, Instagram, and Reddit, to obtain information about mental health and psychiatric disorders. Such content may facilitate mental health literacy, validation, and help seeking, but may also expose users to misinformation, oversimplified diagnostic narratives, and algorithmically reinforced content. Aim To examine the potential benefits and risks of mental health self-diagnosis through social media among adolescents and young people, with …

27.08.2026journal-article

Journal of Applied Research in Higher Education

Preparing sustainability-ready graduates: how identity and digital media literacy shape pro-environmental engagement in higher education

Edy Sabara, Jamaluddin Jamaluddin, Nurul Mukhlisah Abdal, Muhammad Asriadi, Wirawan Setialaksana

Purpose This study extends the theory of planned behaviour (TPB) by integrating ecomedia literacy and ecocultural identity to explain pro-environmental behaviour (PEB) among university students in Indonesia. It examines how cognitive, affective and socio-digital factors jointly shape sustainability engagement in higher education. Design/methodology/approach A quantitative, non-experimental cross-sectional design used an online survey distributed from 17 to 30 November, 2025 to 514 students across Indonesian univers …

27.08.2026journal-article

Frontiers in Medicine

Treatment and clinical outcomes among stage II–IVA nasopharyngeal carcinoma patients with undetectable pretreatment Epstein-Barr viral DNA

Ci-ming Sun, Zhen Xu, Cheng-hao Li, Jun-xiang Chen, Xin-yi Su, Jing-xia Song, Shuang-hong Song, Qing-qing Xu, Yan-Ling Wu

Background This study analyzed the efficacy of multiple combined chemotherapy modalities on the long-term survival outcomes in stage II–IVA nasopharyngeal carcinoma (NPC) patients with undetectable pretreatment Epstein-Barr viral DNA (pre-DNA). Patients and methods We retrospectively analyzed 2,440 patients with stage II–IVA NPC with undetectable pre-DNA. Patients received any of the following treatment modalities: intensity-modulated radiotherapy (IMRT) alone; concurrent chemoradiotherapy (CCRT); induction chemoth …

27.08.2026journal-article

International Journal of Humanity and Social Sciences

Examining the Role of Employee Mental Well-Being in Enhancing Work Engagement and Task Performance among Health Employees in the Public Sector: The Case of Chibombo District

Lungowe Chindele, Chilayi Mayondi, Victor Chikampa, Jacqueline Siwale, Angelo Salasini, Chimuka Mwaanga

Purpose: The study examined the role of employee mental well-being in enhancing work engagement and task performance among public sector healthcare workers in Zambia. Drawing on the Job Demands–Resources (JD-R) Theory, the study proposed that employee mental well-being promotes work engagement, which subsequently enhances task performance. It further assessed whether mental well-being and work engagement significantly predict employee task performance. Methodology: A quantitative cross-sectional survey design was e …

27.08.2026journal-article

Basic & Clinical Pharmacology & Toxicology

Plant‐Derived Heterocyclic Compounds: A Promising Review on Natural Remedies for Rheumatoid Arthritis Management and Their Mechanistic Insights in Inflammation and Joint Protection

Jindong Dai, Xue Xia, Xincheng Hu, Thangamani Kanagaraj, Kanagaraj Rajalakshmi, Mangirish Deshpande, Natarajan Kiruthiga, Dongwei Zhu, Yisun Fan

ABSTRACT Rheumatoid arthritis (RA) represents a persistent autoimmune disease that causes continuous joint inflammation and results in synovial tissue overgrowth and worsening cartilage breakdown together with degeneration of bones. The existing pharmaceutical treatments provide symptom management although they create important adverse effects and raise ongoing security concerns. Plant‐derived heterocyclic compounds present themselves as promising pharmaceutical substitution options because they demonstrate a wide …

27.08.2026journal-article

Philosophical Transactions of the Royal Society B: Biological Sciences

Functions of the EGFR in health and disease

Thomas Bauer, Martin Holcmann, Maria Sibilia

Abstract The epidermal growth factor receptor (EGFR) is a critical mediator of cellular physiology, and its deregulation is implicated in a broad spectrum of pathological conditions, ranging from skin disorders to epithelial malignancies and brain tumours. Although lack of EGFR signalling primarily affects skin and brain development and tissue homeostasis, aberrant EGFR activation through overexpression or mutation converts the receptor into a potent oncogenic driver. This occurs particularly in human cancers such …

27.08.2026journal-article

Journal of Applied Clinical Medical Physics

Fast fourier transform based spectral features for machine learning prediction of gamma passing rates in virtual VMAT PSQA: A feasibility study

Bing Yan, Hu Peng, Xudong Xue, Chichao Zheng, Aidong Wu

Abstract Purpose This study aimed to evaluate the feasibility of fast Fourier transform (FFT) based spectral features for predicting volumetric modulated arc therapy (VMAT) gamma passing rates (GPRs) in virtual patient‐specific quality assurance (PSQA). Methods A total of 481 VMAT treatment plans were retrospectively collected. Multileaf collimator (MLC) trajectories and monitor units (MU) were extracted from control points (CPs) and interpolated onto a uniform gantry‐angle grid. FFT‐based power spectra were then c …

27.08.2026journal-article

Journal of Medical and Dental Investigations

An overview of intraoral scanners and computer-aided design software programs used in scan design stages in digital dentistry

Muhammed Burak Süzen, Hayriye Yasemin Yay Kuşçu

In prosthetic dental treatments, obtaining the negative of the prepared area in the most accurate way directly affects the success of the restoration to be made. Therefore, it is necessary to give importance to the impression material and the impression technique used. Impression materials have undergone changes over the years in order to record the most accurate and sensitive detail. Studies have tried to improve many physical and chemical properties of the impression material. Despite this, it should not be forgo …

27.08.2026journal-article

Journal of Health Organization and Management

Hospital work environment and perceived workforce productivity: a structure–process–outcome perspective from Thailand's healthcare sector

Zulfiqar Ali Jumani, Tachaya Sangkakool, Ruengrumpa Intaraksa, Chila Kaewpraek, Thitika Kaewsomwong

Purpose This study examines how hospital environmental conditions influence perceived workforce productivity through the mediating roles of organizational support and job satisfaction. Grounded in Donabedian's structure–process–outcome (SPO) framework and informed by motivational theory, the study conceptualizes productivity as an organizational outcome shaped by structural and psychosocial processes rather than as a purely technical measure. Design/methodology/approach A quantitative, cross-sectional survey was co …

27.08.2026journal-article

Journal of Clinical Medicine

Bad Ragaz Ring Method Versus Halliwick Method in Verbally Cooperative Children with Spastic Cerebral Palsy (GMFCS Levels I–II): A Pilot Comparison Study

Na-Yeon Ye, Eun-Ju Lee

Background/Objectives: Aquatic therapy is widely used for children with cerebral palsy (CP), but existing approaches such as the Halliwick method focus primarily on postural control and mobility with limited active resistance exercise. The Bad Ragaz Ring Method (BRRM) integrates proprioceptive neuromuscular facilitation (PNF) diagonal patterns with closed kinetic chain (CKC) exercise in the aquatic environment, yet its direct application to children with spastic CP has rarely been examined. This pilot study compare …

27.08.2026journal-article

Revista ft

Da gestão tradicional à gestão inteligente: como automação, dados e inteligência artificial estão transformando a administração

Mayara Pires dos Santos Freitas

Administration is undergoing a transformation driven by advances in automation, data analysis, and artificial intelligence. Processes that previously depended on manual controls and repetitive tasks are being replaced or complemented by tools capable of organizing information, optimizing activities, and supporting decision-making. This article presents a reflection on the transition from traditional management to more intelligent management, highlighting that the adoption of technology, by itself, does not guarante …

27.08.2026journal-article

JAMA Network Open

A Multilevel Intervention to Identify Individuals for Genetic Testing and Treatment

Kirsten A. Jorgensen, Nuria Agusti, Tara Coffin, Karla Barajas, Maria D. Iniesta, Erica M. Bednar, Alexa Kanbergs, Roni Nitecki Wilke, Isabel Beshar, Sara Pirzadeh-Miller, Sayoni Lahiri, Kathy Pratt, Kristofer Jennings, Heidy Bosch, Charles A. Leath, Beth Karlan, Melissa Frey, Ravi Sharaf, Karen Lu, J. Alejandro Rauh-Hain

Importance Cascade genetic testing (CGT) is a key strategy for cancer prevention in families with hereditary breast and ovarian cancer syndrome (HBOC) and Lynch syndrome (LS), yet uptake among at-risk relatives remains persistently low, particularly in medically underserved populations where structural and informational barriers limit access to genetic services. Objective To evaluate the feasibility and preliminary effects of IGNITE-TX (Identifying Individuals for Genetic Testing and Treatment), a scalable, bilingu …

27.08.2026journal-article

Kōtuitui: New Zealand Journal of Social Sciences Online

‘Reflecting Humanity, Or Lack of It’: Ancestral Intelligence and Whakapapa Authority in Wāhine From Gang Whānau

Paora Moyle

The body is where ancestral intelligence operates, where colonial harm has accumulated over generations, and where healing becomes physically possible. Mana Wāhine scholarship has theorised wāhine Māori authority as ancestral and structural, transmitted through whakapapa and whenua. How that authority lives in the body has remained under‐theorised. This article works from pūrākau shared by 20 wāhine Māori from gang whānau over 2 years of engagement, gathered using a Mana Wāhine pūrākau methodology. Four expressions …