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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
11.08.2026journal-article

International Journal of Innovative Technologies in Social Science

TEN-YEAR KETOGENIC DIET AS PRIMARY THERAPY IN SCN2A-RELATED DRUG-RESISTANT DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY: LONG-TERM EFFICACY, SAFETY, AND MULTISYSTEM OUTCOMES

Bartosz Wójtowicz, Szymon Skrzypek, Oliwia Żmuda, Jakub Jasionka, Jagoda Niczyporuk, Patrycja Okoń, Jan Lejman, Magdalena Chrościńska- Krawczyk

Objective: This case study reports a decade-long (2016–2026) follow-up of a girl with gene-confirmed SCN2A-related developmental and epileptic encephalopathy (DEE) in whom the ketogenic diet (KD) was used as primary therapy after failure of eight sequential antiseizure regimens. Methods: Retrospective analysis of hospital records (2013–2026) covering perinatal history, genetic diagnosis, drug therapy, dietary protocol modifications, and serial laboratory, imaging, and electrophysiological surveillance. Results: Cla …

11.08.2026journal-article

WORK: A Journal of Prevention, Assessment & Rehabilitation

Workload assessment in manual materials handling tasks in rice mills in India

Bista Surya Kumar Chhetry, Krishna Narayan Dewangan

Background Manual materials handling (MMH) tasks in rice mills in India are labour intensive. Objective Investigation of physical workload on seven manual material handling (MMH) tasks among male workers in rice mills and comparison of the VO 2 obtained from experiments in the present study with the models developed for Indian workers. Methods Experiments were performed to measure the working heart rate (HR) in the eight rice mills and submaximal test was performed to measure oxygen uptake (VO 2 ) in the laboratory …

11.08.2026journal-article

Journal of Occupational and Organizational Psychology

The protective role of sleep in tempering the impact of ICT ‐driven off‐hour interruptions on exhaustion at work

Angela R. Grotto, Rui Sundrup, Maura J. Mills

Abstract Off‐hour work interruptions are prevalent in organizations that expect employee availability during off‐hours through information‐communication technologies (ICTs). We bring together domain switch theory and threaded cognition theory to argue that ICT availability demands increase off‐hour interruptions during periods intended for generating work‐relevant resources, resulting in exhaustion at work. We sought to identify how individuals could buffer this threat. While to date the literature has primarily ex …

11.08.2026journal-article

Journal of Speech, Language, and Hearing Research

Case Studies of Auditory Processing Assessment and Management for Veterans

Melissa A. Papesh

Purpose: Clinical care for patients who report substantial hearing difficulties despite having little or no hearing loss is a topic of great debate within and beyond audiology. Building on our previous retrospective review of veterans evaluated for auditory processing disorders across the Veterans Health Administration (VHA), the current work presents five such case studies. The goal is to work toward improved patient care by providing a more in-depth view highlighting both strengths and weaknesses of approaches to …

11.08.2026journal-article

Journal of Speech, Language, and Hearing Research

Construction of a Prediction Model for Naming Recovery in Subacute Poststroke Aphasia Based on Multivariate Analysis: Evaluation of Accuracy and Reliability

Zhifang Sun, Linlin Ye, Yi Shan, Lei Cao, Bixiao Cui, Jie Wang, Dahua Zhang, Yinan Cheng, Tiantian Zhang, Yuting Zhao, Weiqun Song, Jie Lu

Purpose: Anomia, a common dysfunction in poststroke aphasia (PSA), impacts daily communication, and its prognosis remains challenging. This study aimed to develop a model to predict naming rehabilitation in patients with subacute PSA. Method: Data of PSA were collected retrospectively. Logistic regression (LR) analyses by a nested fivefold cross-validation were performed to identify predictors and construct a predictive model. The efficacy of the model was evaluated using receiver operating characteristic (ROC) cur …

11.08.2026journal-article

Journal of Speech, Language, and Hearing Research

Visual–Spatial Influences on Vocal Intensity: Effects of Speaker-to-Listener Distance and Room Size in Immersive Virtual Reality

Ümit Daşdöğen, Joseph Hitchcock, Seungjun Ahn, Bailee Brooke Ng, Katherine Verdolini-Abbott

Objectives: The aim of this study was to investigate the effects of speaker-to-listener distance versus room size on individuals' voice perception and production using immersive virtual reality (IVR). Method: Fifteen vocally healthy participants completed three speaking tasks: sustained vowel /a/, the standardized phrase “We were away a year ago,” and spontaneous connected speech in nine randomly ordered IVR conditions. Conditions varied in room size, speaker-to-listener distance, and combinations of room size × sp …

11.08.2026journal-article

Journal of Speech, Language, and Hearing Research

Prosodic Synchrony Profiles in Mandarin-Speaking Children With Autism, Developmental Delay, and Typical Development: A Multi-Timescale Analysis

Tongxin Yin, Saige Qin, Yuexin Zhang, Jie Wang, Lian Xu, Xuling Han, Xinyu Hu, Yanxia Wang, Mudi Sun, Lu Qu, Haidan Lu, Hang Zhao, Min Liu, Qiaoyun Liu

Purpose: Prosodic synchrony differences between autistic and non-autistic individuals have been increasingly documented, but findings remain heterogeneous. This study delineates a multi-timescale profile of static and dynamic pitch synchrony in autistic children during naturalistic Mandarin caregiver–child interactions to deepen understanding of interactional characteristics in autism. Method: Sixty Mandarin-speaking children with autism spectrum disorder (ASD), developmental delay, or typical development (TD) part …

11.08.2026journal-article

Encyclopedia

School-Based Speech–Language Therapy Services for Children with Hearing Loss in Inclusive Education: A Narrative Review

Duygu Büyükköse, Merve Nur Sarıyer Temelli

Children with hearing loss increasingly participate in inclusive educational settings; however, many continue to experience difficulties in language development, communication access, and classroom participation. This narrative review examines school-based speech–language therapy (SLT) services for children with hearing loss in inclusive educational settings, focusing on language development, service delivery models, and intervention practices. The reviewed literature suggests that language development in children …

11.08.2026journal-article

Blood Cancer Discovery

Glofitamab-Based Therapy for Relapsed or Refractory CNS Lymphoma: A Multicenter Retrospective Study

Ruixian Xing, Apeng Yang, Juan Huang, Liang Wang, Wei Guo, Qu Cui, Xiaoqiong Tang, Yuanyuan Ma, Kai Hu, Tianheng He, Danyang Wu, Xiaofang Deng, Yajing Zhang, Kaili Zhong, Yang Liu, Yixian Guo, Ying Wang, Chan Long, Chongyang Wu, Xin Lu, Fengmin Li, Jiefei Bai, Jun Qian, Xuefei Sun, Wenrong Huang, Hui Zhou, Huilai Zhang, Ou Bai, Xiaobing Huang, Zhiyong Zeng, Lin Fu

Abstract Relapsed or refractory CNS lymphoma (R/R CNSL) has limited treatment options. This multicenter retrospective study enrolled 84 consecutive R/R CNSL patients (median age 59 years; 53 PCNSL, 31 SCNSL) to evaluate efficacy and safety profiles of glofitamab therapy. With a median of 2.5 prior lines of therapy, the objective response rates (ORR) and complete response rates (CRR) for PCNSL were 88% (CRR 59%) with glofitamab monotherapy (n=32) and 100% (CRR 81%) with combination therapy (n=21), respectively; for …

11.08.2026journal-article

JMIR mHealth and uHealth

Characteristics of Tailored Text Messages Associated With Increased Physical Activity Among Cardiac Rehabilitation Enrollees: Secondary Analysis of a Microrandomized Trial

Namratha Atluri, Kashvi Gupta, Tanima Basu, Evan Luff, Jieru Shi, Thomas Boyden, Bhramar Mukherjee, Sachin Kheterpal, Predrag Klasnja, Walter Dempsey, Brahmajee K Nallamothu, Jessica R Golbus

Background Emerging data suggest that text message–based mobile health interventions may enhance physical activity levels in patients with cardiovascular disease enrolled in cardiac rehabilitation. The optimal characteristics of texts that lead to maximal patient engagement and drive meaningful behavioral change are not well understood. Objective This study aimed to understand how text- and participant-level characteristics impact physical activity levels after text delivery. Methods The VALENTINE (Virtual Applicat …

11.08.2026journal-article

Journal of Speech, Language, and Hearing Research

Bayesian Multivariate Linear Mixed-Effects Models for Speech Research: A Tutorial Using brms

Na Hu, Paul-Christian Bürkner, Amalia Arvaniti

Purpose: When studying how factors influence multiple outcomes (e.g., acoustic measures in phonetics), researchers often analyze each outcome separately using a univariate approach. However, this approach ignores relationships between outcomes, which can reduce estimate accuracy and make it difficult to examine how effects are related across outcomes. A multivariate approach addresses these issues by modeling all outcomes jointly. This tutorial illustrates how to fit Bayesian multivariate linear mixed-effects model …

11.08.2026journal-article

Journal of Endovascular Therapy

Superficial Temporal Artery Access for Angiography in a Patient With Leriche Syndrome, Subclavian Artery Occlusions, Multiple Acute Arterial Thromboses, and Heart Failure

Tomislav Krčmar, Petra Grubić Rotkvić, Tomislav Tokić, Zvonimir Ante Korda, Majda Vrkić Kirhmajer, Mislav Puljević, Hrvoje Gašparović, Joško Bulum

Despite significant progress in revascularization techniques, the vascular approach itself can still be a challenge in complex polyvascular disease. In this case report, we describe the feasibility of a potentially underutilized alternative vascular approach in a patient with multiple arterial occlusions who presented to our hospital with acute multivessel thromboses and chronic occlusions of the distal aorta and subclavian arteries, which rendered noninvasive blood pressure measurements unreliable. The patient als …

11.08.2026journal-article

Artefactum - revista de estudos interdisciplinares

INTER-RATER RELIABILITY OF THE RÉGIS SCALE™: A CLINICAL DECISION SUPPORT TOOL FOR STANDARDIZING PHYSICAL THERAPY FREQUENCY RECOMMENDATIONS IN HOME-BASED NEUROLOGICAL REHABILITATION

Régis Ferraz Cornélio Goiana Novaes

Determining the appropriate frequency of Physical Therapy sessions in home-based neurological rehabilitation remains one of the most subjective decisions in clinical practice. Although several instruments assess functional status and disability, no widely adopted tool has been specifically designed to standardize treatment frequency recommendations. The Régis Scale™ was developed as a Clinical Decision Support Tool (CDST) to support evidence-based and standardized Physical Therapy frequency recommendations. Followi …

11.08.2026journal-article

Die Rehabilitation

Exklusionsrisiken bei eingeschränkter Erwerbsfähigkeit: „Das ist nicht vorgesehen im System, dass man so viel krank ist.“

Betje Schwarz, Katja Nebe

Zusammenfassung Chronische Erkrankungen können gesellschaftliche Teilhabe entscheidend beeinträchtigen und Desintegration, Armut und Vereinsamung nach sich ziehen. Ziel ist es, Exklusionsrisiken von Menschen nachzuzeichnen, deren Erwerbsfähigkeit erkrankungsbedingt gefährdet oder bereits gemindert ist. Grundlage bilden problemzentrierte Interviews mit 50 bei der Deutschen Rentenversicherung (DRV) Bund bzw. Nord versicherten Menschen, die gemäß DRV-Routinedaten ein hohes Risiko für einen vorzeitigen, erkrankungsbedi …

11.08.2026journal-article

International Journal of Physiotherapy and Research

Impact of Calf Muscle Spasticity on Tibialis Anterior Muscle Activation in Chronic Stroke Patients: A Cross-Sectional Study

Jagruti Patel, Dhwanit Shah

Background: Calf muscle spasticity is a common consequence after stroke and can impede the functional activation of antagonist muscles such as the tibialis anterior, affecting gait and mobility. Objective: To determine the relationship between calf muscle spasticity severity (via Modified Ashworth Scale, MAS) and tibialis anterior activation (via RMS, surface EMG) in chronic stroke patients. Methods: Cross-sectional study on 108 chronic stroke patients aged 35–65 years. Variables included Age, Gender, Side, MAS for …

11.08.2026journal-article

Revista ft

Laserterapia na prevenção e tratamento de mucosite oral em pacientes oncológicos: uma revisão de literatura

Emylle Tainah de Almeida da Silva, Geovana dos Reis Dias

Oral mucositis is frequently observed as a complication in patients undergoing antineoplastic therapies, being characterized by pain, inflammation, and ulcerations of the oral mucosa, factors that significantly compromise quality of life and may lead to the temporary or permanent interruption of oncological treatment. Low-level laser therapy has been indicated as a promising therapeutic alternative for the prevention and treatment of this condition, due to its anti-inflammatory, analgesic, and regenerative properti …

11.08.2026journal-article

Medicine: theory and practice

Особенности медикаментозной терапии артериальной гипертензии в амбулаторной практике

Наталия Михайловна Козлова, Алина Сергеевна Смирнова

Введение. Артериальная гипертензия, будучи ключевым модифицируемым фактором риска сердечно-сосудистых заболеваний, остается глобальной проблемой общественного здравоохранения. Несмотря на наличие эффективных стратегий лечения, достижение целевых уровней артериального давления в реальной клинической практике часто остается неудовлетворительным. Цель исследования — анализ возрастных особенностей и современных тенденций в назначении антигипертензивной терапии, а также оценка соответствия выявленных терапевтических под …

11.08.2026journal-article

American Journal of Physical Medicine & Rehabilitation

Supply Chain Break For Medications in Physical and Rehabilitation Medicine

Ahmad J. Abdulsalam, Yousef Abdulsalam, Mahmoud M. El-Mas, Levent Özçakar

Pharmaceutical supply chain disruptions from pandemics, natural disasters, and geopolitical conflicts increasingly threaten medications central to rehabilitation practice. Rehabilitation pharmacotherapy is especially exposed because many core agents have narrow therapeutic windows, require cold-chain logistics, lack ready substitutes, or carry life-threatening consequences when abruptly interrupted. This analysis examines vulnerabilities across three rehabilitation medication categories: spasticity-targeted therapi …

11.08.2026journal-article

Journal of Nephrology

Renal Volume Reduction on Magnetic Resonance Imaging During Tolvaptan Therapy in Patients with ADPKD: A Case Series

İsmail Koçyiğit, Emre Aydın, İsmail Baloğlu, Kader Kılıç, Alparslan Demiray

Abstract The primary effect of tolvaptan therapy in autosomal dominant polycystic kidney disease (ADPKD) is to slow the rate of kidney volume increase and thereby delay progression to end-stage renal disease; however, an actual reduction in kidney volume has rarely been reported. We evaluated four patients with ADPKD who demonstrated a decrease in kidney volume on magnetic resonance (MR) imaging during tolvaptan treatment. This observational case series included four patients who underwent regular clinical and MR e …

11.08.2026journal-article

Journal of Speech, Language, and Hearing Research

Physiologic Adaptations to Modifying Resistive Load and Time Under Tension During Expiratory Muscle Strength Training

Avery E. Dakin, Sydney Rau, Katya Villarreal-Cavazos, Kelly Easterly, Jessica E. Huber, Carol Ewing Garber, Lori Quinn, Karen W. Hegland, Michelle S. Troche

Purpose: The purpose of this study was to test the impact of modifying resistive load and time under tension (TUT) on respiratory excursion, submental excitation, and ratings of perceived exertion/effort (RPE) during expiratory muscle strength training (EMST). Task specificity between EMST, cough, and swallowing was also explored. Method: Participants were outfitted with respiratory bands, submental surface electromyography, and a microphone. Tasks included maximal expiratory pressure (MEP) testing, voluntary and r …

11.08.2026journal-article

Trials

Efficacy of neuromuscular electrical stimulation as a therapy for sarcopenia in people on haemodialysis: study protocol for the STIM-HD randomised controlled trial

Emma L. Watson, Niamh Quann, Faizan Awan, Shaun R. Barber, Nicola Cooper, Indranil Dasgupta, Jonathan P. Folland, Laura J. Gray, Gordon McGregor, Jakob Škarabot, Meghan Tanel, Cat Taylor, James O. Burton

Abstract Background Sarcopenia is highly prevalent among adults receiving haemodialysis and is associated with reduced physical function, impaired quality of life, and increased morbidity and mortality. Although structured exercise programmes can improve muscle health, most people receiving haemodialysis are unable or unwilling to participate, highlighting the need for accessible alternatives. Neuromuscular electrical stimulation (NMES) is a non-volitional method of muscle contraction that may act as an ‘exercise m …

11.08.2026journal-article

International Journal of Physiotherapy and Research

Effect of Speed Intensive Gait Training on Balance, Gait Speed, and Endurance in Patients with Chemotherapy-Induced Peripheral Neuropathy

Geetu Vikram Ahuja, Sabah Thaver, Ali Irani

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a common complication of neurotoxic chemotherapy and is associated with sensory deficits, impaired balance, reduced gait speed, and decreased endurance, resulting in reduced functional mobility and increased fall risk. Exercise-based rehabilitation interventions have shown promise in improving functional outcomes in individuals with CIPN. This study aimed to compare the effects of treadmill training and speed-intensive gait training on balance, gait s …

11.08.2026journal-article

Physiotherapy Research International

Development and Content Validation of an Exercise‐Based Framework for the Management of Lumbar Radiculopathy

Shashwath P. Naidu, Anjali Suresh, Sarulatha Haridass, Karvannan Harikesavan

ABSTRACT Background and Purpose Current guidelines for the management of lumbar radiculopathy recommend patient education, staying active, manual therapy, and nonsteroidal anti‐inflammatory drugs (NSAIDs) as first‐line treatments. Physiotherapy‐specific interventions for low back pain that radiates to the leg include specific trunk muscle activation, muscle strengthening and endurance, movement control, centralisation, directional preference exercises and nerve mobilisation. While exercise therapy is widely recogni …