Frontiers in Immunology
Serum IL-6 and functional outcome after endovascular therapy: the mediating role of infarct volume growth in acute ischemic stroke
Background and purpose Inflammatory factors are pivotal in systemic and central nervous system inflammation post-stroke. This study examined if peripheral inflammatory factors were associated with outcomes after endovascular therapy for acute large vessel occlusion stroke by mediating infarct growth. Methods We conducted a retrospective analysis of the EVTRNA (Circulating Non-coding RNA in Acute Ischemic Stroke with Endovascular Treatment) trial. Patients who underwent pre-endovascular therapy multimodal MRI, posto …