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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

Frontiers in Pediatrics

Risk factors for abnormal bone mineral density in Duchenne muscular dystrophy and the association of regular rehabilitation with bone health

Yi Chen, Shaowei Dong, Meihuan Huang, Guixiang Liu, Turong Chen, Chunming Zhou, Mingsheng Zhang

Background We investigated the prevalence and risk factors of abnormal bone mineral density (BMD) in Duchenne muscular dystrophy (DMD) and explored the potential association of regular rehabilitation with BMD. Methods A cross-sectional study including 215 boys with DMD was conducted. Multivariate logistic regression was used to identify independent predictors, and mediation analysis was performed to explore the pathway linking rehabilitation and BMD. Results Abnormal BMD was found in 62 patients (28.8%). Age was th …

27.08.2026journal-article

Frontiers in Public Health

Association of meteorological exposures with major cancer mortality in Minhang District, Shanghai: a time series study based on distributed lag non-linear models

Jiaqi Guo, Junhui Huang, Chao Xu, Shuili Xuan, Jingyi Ni, Wei Liu, Linli Chen, Yibin Zhou

Objective This study examined the associations between meteorological exposures and major cancer mortality, with a focus on exposure-lag relationships. Methods We collected daily cancer death records and weather data from Minhang District, Shanghai, 2014 to 2023. Joinpoint regression estimated annual percent changes in age-standardized cancer mortality rates. Spearman's rank correlation was employed to explore how meteorological factors related to cancer death. Finally, a distributed lag non-linear model (DLNM) eva …

27.08.2026journal-article

Frontiers in Public Health

Assessment of awareness, usage, and attitudes toward nicotine pouches in Saudi Arabia: a cross-sectional study

Hussain Khalifa Aljumah, Hassan Ali Alradhi, Mujtaba Abbas Alzuwayr, Manal Yousef Alturaifi, Maryam Ali Alamer, Mohammed Naji Albannay, Abdullah Almaqhawi

Background Nicotine pouches (NPs) are emerging smokeless nicotine products marketed as tobacco-free alternatives to traditional smokeless tobacco products. Despite their growing popularity, particularly among youth, limited research exists on their awareness, usage, and attitudes in Saudi Arabia. Objectives This study aimed to assess awareness, usage patterns, and attitudes toward NPs among adults in Saudi Arabia. Methods A cross-sectional, online survey targeting Arabic-speaking adults was conducted between 6 Marc …

27.08.2026journal-article

TEM Journal

Predictors of the Effective Implementation of Artificial Intelligence Tools in Mathematics Education of Pre-Service Primary Teachers

Dušana Babicová, Štefan Tkačik, Zlatica Huľová, Štefan Tkačik Jr, Peter Tokoš

Previous research suggests that math anxiety is common among prospective teachers, is associated with less positive attitudes toward math, and may later affect their students. At the same time, AI tools and educational podcasts appear promising for personalized support of self-study in mathematics education. The aim of this study is to establish a baseline profile of selected predictors prior to the planned implementation of an AI assistant for self-study in mathematics. Five research questions examined the relatio …

27.08.2026journal-article

Australian Health Review

Understanding Australian community members’ knowledge of concussion: a cross-sectional nationwide survey

Sara L. Whittaker, Aleksandra K. Gozt, Lisa Licciardi, Naomi Fuller, Melinda Fitzgerald, Shenane Hogg, Natasha K. Brusco

Objective This study aimed to establish current Australian community knowledge of: (i) mechanisms of concussion injury; (ii) concussion signs and symptoms; (iii) concussion response and management; (iv) pathways of seeking help for a suspected concussion; (v) recovery journey after sustaining a concussion; and (vi) community misbeliefs about concussion. Methods An online survey measured current knowledge of concussion held by the Australian community (≥18 years). Convenience sampling was used for national data coll …

27.08.2026journal-article

TEM Journal

Digital Transformation in Family SMEs: The Effects of Family Involvement, Culture, and Human Resource Skills

Abderrahim Masmoud, Youssef Tichoua

Digital transformation enables companies, including family SMEs, to survive and adapt to an environment full of change. Family SMEs have specific characteristics that affect every part of the company. Therefore, the objective of this research study is to examine the effect of family involvement, culture, and human resource skills on digital transformation. A quantitative study was conducted using structural equation modeling with SMART PLS 4 to analyze survey responses from 172 Moroccan family SMEs operating in the …

27.08.2026journal-article

BMC Public Health

Cumulative digital risk exposure and self-harm behavior among Indonesian adolescents

Triyana Harlia Putri, Fitri Ariyanti Abidin, Meita Dhamayanti, Popy, Fitri Fujiana, Aprida Manurung, Suryani Suryani

Abstract Background Self-harm behavior (SHB) among adolescents is a growing public health concern, particularly in the digital era. Exposure to digital risks such as online gaming addiction and cyberbullying victimization may increase vulnerability, especially when multiple risks co-occur. This study examined the association between cumulative digital risk exposure and SHB among Indonesian adolescents and identified associated psychosocial factors. Methods A cross-sectional study was conducted among 1,742 Indonesia …

27.08.2026journal-article

Journal of Clinical Medicine

Late-Course Lactate/Albumin Ratio and In-Hospital Mortality in CRRT-Treated Critically Ill Patients: A Retrospective Severity-Adjusted Analysis

Hasan Şenay, Mehmet Kürşad Orhan, Mahmut Sami Tutar, Munise Yıldız, Ece Ünüvar Şenay, Muhammed Halit Satıcı, Ahmet Erarkadaş, Betul Kozanhan

Background/Objectives: The lactate/albumin ratio (LAR) integrates tissue hypoperfusion and nutritional reserve into a single dimensionless index. As a late-course measurement (last available value before the primary outcome), it may reflect terminal metabolic deterioration rather than early prognostic signal. We examined the association of the final LAR with in-hospital mortality after adjustment for validated severity scores (APACHE II, SOFA) in critically ill patients receiving CRRT, and evaluated its incremental …

27.08.2026journal-article

International Journal of Molecular Sciences

Beyond Swelling: Clinical Insights into the Diagnosis and Management of Hereditary Angioedema

Margarita Paulauskiene, Laura Tamasauskiene, Brigita Gradauskiene

Hereditary angioedema (HAE) is a rare genetic disorder characterized by recurrent episodes of severe, non-pitting edema, most commonly caused by a deficiency or dysfunction of C1 esterase inhibitor (C1-INH), resulting in excessive bradykinin production. HAE subtypes differ according to C1-INH levels, functional activity, underlying genetic variants, and increasingly recognized molecular mechanisms. Awareness of HAE outside specialized medical fields remains limited, and recurrent angioedema may arise through differ …

27.08.2026journal-article

ICEETE Conference Series

Digital Platforms For Sustainability Education In Indonesia: A Systematic Review Of Usability And Equity

Cavin Agustinus Sitorus, Anggel Maria Savrila, Freddy Matius Herdia

Climate change and declining environmental awareness among youth have made sustainability education a national priority in Indonesia, and digital platforms are increasingly promoted as scalable enablers of this agenda. Their integration into formal education, however, remains uneven and is constrained by infrastructure gaps and disparities in digital literacy across the archipelago. While prior systematic reviews have examined digital tools for environmental education globally, and separate reviews have mapped envi …

27.08.2026journal-article

The Journal of Clinical Endocrinology & Metabolism

Neuroimaging Abnormalities and Genotype-Phenotype Correlations in Noonan Syndrome: A Multicenter Cohort Study

Giuseppa Patti, Nadia Gabriella Maiorano, Francesca Piccoli, Alice Zucconi, Maria Grazia Calevo, Federica Tamburrino, Emanuela Scarano, Concetta Schiavariello, Cesare Rossi, Laura Mazzanti, Eleonora Orlandini, Gabriella Pozzobon, Martina Finamore, Cristina Baldoli, Anna Grandone, Mario Cirillo, Francesca Aiello, Domenico Corica, Malgorzata Wasniewska, Alessandro Cattoni, Paolo Remida, Donatella Capalbo, Fabio Tortora, Maria Carolina Salerno, Sara Azzolini, Mariam Mansour, Maria Felicia Faienza, Stefano Palladino, Domenico Tortora, Giulia Rosti, Francesca Faravelli, Cristina Venturino, Pasquale Capuozzo, Letizia De Mori, Paola Maietta, Anna Elsa Maria Allegri, Chiara Morreale, Alessia Angelelli, Flavia Napoli, Natascia Di Iorgi

Abstract Context Neuroradiological findings in Noonan syndrome (NS) remain insufficiently characterized Objective To characterize neuroimaging abnormalities in children with genetically confirmed NS and evaluate their associations with clinical phenotype Design, Setting, and Participants In this multicenter retrospective study, brain MRI scans and longitudinal clinical and genetic data were reviewed from children with genetically confirmed NS evaluated between 2008 and 2023 at seven pediatric endocrinology centers …

27.08.2026journal-article

BMC Oral Health

Parental knowledge, attitude, and practice on oral complications of leukemia treatment: a cross-sectional study

Nosrat Nourbakhsh, Ailar Adib Haji Bagheri, Maryam Torkian, Sheida Bagheri, Sahar Talebi

Abstract Background Leukemia is among the most common childhood cancers, and treatments such as chemotherapy and radiotherapy often lead to oral and dental complications. With rising survival rates, attention to oral health and its impact on quality of life has become increasingly important. Parental knowledge and practice play a vital role in preventing and managing these complications. Therefore, this study assessed the knowledge, attitude, and practice (KAP) of parents of children with leukemia regarding oral sy …

27.08.2026journal-article

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi

Microsurgical Aspects of Middle Cerebral Artery Variations: Clinical and Anatomo-radiological Implications

Mustafa Eren Yüncü, Berra Bilgin, Yeliz Pekçevik, Ali Karadag, Necmettin Tanrıöver

The middle cerebral artery is the largest branch of the internal carotid artery and supplies extensive cortical and deep cerebral territories. Variations in its branching pattern are of considerable importance in microsurgical planning and may influence aneurysm development. This study aimed to evaluate the prevalence of middle cerebral artery variations, their microsurgical anatomy, and their relationship with anterior circulation aneurysms. Computed tomography angiography images of 500 patients were retrospective …

27.08.2026journal-article

Academia Nutrition and Dietetics

Beyond glycemia: clinical nutrition in type 2 diabetes and cardiometabolic risk

Antonio Maria Labate, Provvidenza Villari

Type 2 diabetes (T2D) is a multifactorial cardiometabolic disorder in which dysglycemia coexists with visceral adiposity, insulin resistance, atherogenic dyslipidemia, hypertension, and metabolic dysfunction-associated steatotic liver disease (MASLD). In this setting, clinical nutrition should be considered a therapeutic intervention rather than a generic lifestyle add-on. This mini-review summarizes how nutritional strategies can modify major cardiometabolic domains in adults with T2D, with a practical focus on Me …

27.08.2026journal-article

Diabetes Obesity and Cardiometabolic CARE

Electronic Health Record–Based Algorithms May Improve Identification of Cases of Atypical Diabetes, Including in Groups Underrepresented in Biomedical Research

Victoria Chen, Cristina I. Fernández Hernández, Megan Griff, Julia L. Douvas, Micah Koss, Melton Fan, Will Marshall, Evelyn Greaux, Wyatt Pfau, Marjan Rezaei, Jeremy Graber, Vatsala Singh, Laura K. Wiley, Sridharan Raghavan, Neda Rasouli, Miriam S. Udler, Sara J. Cromer, RADIANT Study Group

OBJECTIVE To determine whether electronic health record (EHR)-based algorithms can identify individuals with atypical diabetes (AD) eligible for the Rare and Atypical Diabetes Network (RADIANT) study and whether these algorithms improve identification and enrollment of individuals from populations underrepresented in biomedical research (UBR). RESEARCH DESIGN AND METHODS Two RADIANT clinical sites independently developed EHR-based algorithms to identify AD phenotypes, including a lean type 2 diabetes–like physiolog …

27.08.2026journal-article

Big Data & Society

Commodifying compassion in the digital age: The promise and perils of tech for good

Maha Rafi Atal, Sofie Elbæk Henriksen, Lisa Ann Richey

Digital and data-driven technologies are transforming the humanitarian and development sectors. With the promise of faster, more efficient and accurate aid delivery, these technologies are often designed and implemented in partnerships between aid organizations and private technology firms. Consequently, “Tech for Good” has emerged as a significant humanitarian domain, where Big Tech companies aspire to create innovative technological solutions to humanitarian problems and link their business interests and strategi …

27.08.2026journal-article

Plant Health Progress

Current Status of Ceratobasidium theobromae Affecting Cacao and Cassava: Diagnosis and Management

Cansu Oksel, Fulya Baysal-Gurel

Ceratobasidium theobromae, the causal agent of vascular streak dieback in cacao, has recently been associated with cassava witches’ broom disease, expanding its known host range and increasing its importance in crop production systems. This review summarizes disease development, diagnosis, and management of C. theobromae in cacao and cassava. Diagnosis remains challenging due to difficulties in pathogen isolation and confirmation of pathogenicity, although molecular tools have improved detection and identification. …

27.08.2026journal-article

BMC Medical Education

Impact of clinical case discussions in anatomy on national exam performance: a 10-year longitudinal cohort study

Fang Fang, Lan Yu, Yetao Ou, Si Zhou, Jun Ma, Yuntao Peng, Fang Liu, Junfeng Wang, Chunbo Xia, Houzhong Li, Weishan Zhang, Tan Cheng, Yu Chen, Yi Huang, Xin Li, Heng Guan

Abstract Background Traditional anatomy instruction often prioritizes structural memorization over clinical application. Although case-based learning is widely endorsed to bridge this theory-practice gap, longitudinal evidence regarding its sustained impact in foundational sciences remains limited, particularly concerning its performance over a decade amid massive enrollment expansion. Methods This 10-year longitudinal retrospective cohort study tracked seven clinical medicine cohorts (2015-2021). To maintain teach …

27.08.2026journal-article

Wellcome Open Research

The genome sequence of the Orange Ripple Bryozoan, Schizoporella japonica Ortmann, 1890 (Cheilostomatida: Schizoporellidae)

John Bishop, Marine Biological Association Genome Acquisition Lab, Darwin Tree of Life Barcoding Collective, Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team, Wellcome Sanger Institute Scientific Operations: Sequencing Operations, Wellcome Sanger Institute Tree of Life Core Informatics team, Tree of Life Core Informatics collective, Darwin Tree of Life Consortium

We present a genome assembly from a specimen of Schizoporella japonica (Orange Ripple Bryozoan; Bryozoa; Gymnolaemata; Cheilostomatida; Schizoporellidae). The genome sequence has a total length of 255.53 megabases. Most of the assembly (99.03%) is scaffolded into 19 chromosomal pseudomolecules. The mitochondrial genome has also been assembled, with a length of 18.45 kilobases. This assembly was generated as part of the Darwin Tree of Life project, which produces genomes for eukaryotic species found in Britain and I …

27.08.2026journal-article

مجلة بيت المشورة

Beyond Infrastructure: Mapping the Gap between Digital Capability and Consumer Trust in Travel Intermediaries (2016-2025)

Doğuş Kılıçarslan

This study maps the thematic structure of the literature on digitalization in travel businesses and traces how that structure changed over a ten-year period. The aim is not only to summarize publication activity but to read the meaning patterns in study abstracts and to describe the field at the level of content. A corpus of 391 studies published between 2016 and 2025 was drawn from the Web of Science and Scopus databases. The corpus was examined with a mixed design that combines a descriptive performance analysis …

27.08.2026journal-article

Frontiers in Global Women's Health

Abdominopelvic hydatid disease during pregnancy: a systematic review of the literature

Evangelos Chinis, Kyriakos Tzanakis, George Lockett, Laura Burney Ellis, Stergios Bobotis, Georgios Geropoulos, Maria Kyrgiou, Konstantinos S. Kechagias

Objective To review the available literature on abdominopelvic cystic echinococcosis (CE) during pregnancy, focusing on clinical presentation, diagnostic approaches, management strategies, and maternal and foetal outcomes. Methods A systematic review was conducted in accordance with PRISMA guidelines. Studies reporting abdominopelvic hydatid disease in pregnant women were included without restrictions on study design or geography. Results Fifty-one studies (45 case reports and 6 case series) including 79 patients w …

27.08.2026journal-article

Clinical and Translational Medicine

PRAME promotes invasion and metastasis of salivary adenoid cystic carcinoma by regulating RARα stability via the cullin2 ubiquitin‐proteasome system

Xudong Wang, Tingyao Ma, Yixin Jing, Tianyi Li, Xi Zhao, Guohan Zhao, Ran Gao, Lu Kong, Xiaohong Chen

Abstract Background All‐trans retinoic acid (ATRA) exerts its biological functions primarily through nuclear receptors, but its therapeutic efficacy in solid tumours remains limited. This study aimed to elucidate the regulatory role of the cancer‐testis antigen PRAME in posttranslational modifications (PTMs) of the ATRA receptor RARα, and to assess its consequent impact on tumour progression in salivary adenoid cystic carcinoma (SACC). Methods Transcriptome sequencing was performed on public datasets from the Gene …

27.08.2026journal-article

Karya Journal of Health Science

RELATIONSHIPS BETWEEN ORTHOREXIA NERVOSA TENDENCY, MINDFUL EATING, AND BODY MASS INDEX IN YOUNG ADULTS (19-32 AGED): A CROSS-SECTIONAL STUDY BASED ON GENDER DIFFERENCES

Murat Altan, Şemsi Gül Yılmaz Kocaman, Hasan Yıldırım

Objective: This cross-sectional study investigated the associations between Orthorexia Nervosa (ON), mindful eating, and body mass index (BMI) among young adults, and explored gender-based differences in ON tendencies and mindful eating.Method: The research was conducted between October and December 2024 in Elazığ, Türkiye, and included 757 healthy participants. Data were collected using face-to-face questionnaires assessing sociodemographic characteristics, the Orthorexia Nervosa-11 Scale (ORTO-11), and the Mindfu …

27.08.2026journal-article

Sustainability

Assessing the Implementation of Artificial Intelligence-Based Systems for Sustainable Solid Waste Management in Selected Countries in Asia, Europe and North America: A Systematic Review

Lynda Andeobu, Santoso Wibowo, Srimannarayana Grandhi

The efficient management of solid waste remains a persistent challenge worldwide, particularly in developing countries, due to increasing waste generation driven by rapid population growth and urbanisation. Artificial Intelligence (AI) has emerged as a transformative approach to improving solid waste management (SWM) by enhancing waste collection, sorting, recycling, and resource recovery processes. Several countries have integrated AI into their SWM systems; however, the extent of AI-driven automation across the S …