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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
24.08.2026journal-article

Journal of Intellectual Disability Research

Parent/Caregiver Perspectives on the Healthcare Decision‐Making Involvement of Young People With Intellectual Disability: A Qualitative Study

Jessica Keeley, Zhenmei Yeap, Thomas Nevill, Rachel Skoss, Aasta Abbott, Sandra Thompson, Sophie Haywood, Rachel Collins, Katherine Langdon, Jenny Downs

ABSTRACT Background Young people with intellectual disability often have complex healthcare needs. Parent/caregivers can enhance their child's involvement in healthcare decision‐making to improve treatment adherence and health outcomes. Healthcare decision‐making is embedded within health literacy skillsets, and for people with intellectual disability additional time and assistance are needed to ensure preferences are included. This study aims to explore parent/caregiver perspectives on the different ways that youn …

24.08.2026journal-article

Investigación e Innovación: Revista Científica de Enfermería

Diabetes Mellitus 2 como factor de riesgo en el desarrollo del Alzheimer en adultos mayores:

Zenaida Leandra Mendive García, Tania de la Caridad García Castellanos, Areli Nicolás Mejía, Caridad Dandicourt-Thomas

La Enfermedad de Alzheimer se considera la principal causa de demencia en los adultos mayores, cursa con un deterioro de las funciones cognitivas, y se asocia a la acumulación de proteína β-amiloide y tau hiperfosforilada en el cerebro. La Diabetes mellitus tipo 2 se considera como un posible factor de riesgo para su desarrollo. Objetivo: sistematizar la evidencia científica sobre la Diabetes Mellitus tipo 2 como factor de riesgo para el desarrollo de la enfermedad de Alzheimer en adultos mayores. Materiales y méto …

24.08.2026journal-article

Revista de Geopolítica

NUTRIÇÃO NO ENVELHECIMENTO: A INFLUÊNCIA DAS PRÁTICAS ALIMENTARES NO PROCESSO DE SENESCÊNCIA

Greice Kelly Costa De Sena, Ranielle Barbosa Saraiva, Beatriz Paiva Rocha, Luisa Camila Rodrigues Gomes, Valéria Silva De Lima, Laíze Moreira De França, Rosiane Oliveira De Sousa, Gleiciane Moreira De Lima, Francisca Karusa Carvalho Barbosa, Ana Luiza de Rezende Ferreira Mendes

A alimentação saudável é fundamental para a promoção, manutenção e recuperação da saúde da população idosa. As alterações decorrentes da senescência podem ser significativamente minimizadas por meio da ingestão adequada de nutrientes que contribuem para o bom funcionamento do organismo. Dessa forma, o objetivo do estudo é analisar os efeitos das práticas alimentares e seus impactos na saúde da população idosa, destacando a importância da intervenção nutricional na promoção do envelhecimento saudável. Trata-se de um …

24.08.2026journal-article

Frontiers in Cardiovascular Medicine

Nonlinear association between remnant cholesterol inflammation index and incident stroke among middle-aged and older adults with hypertension: a CHARLS cohort study

Siyi Jiang, Ying Cui, Lijun Song, Li Li, Min Li

Background The remnant cholesterol inflammation index (RCII) combines remnant cholesterol (RC) and high-sensitivity C-reactive protein (hs-CRP), two markers that may reflect residual lipid-related and inflammatory vascular burden. We examined whether baseline RCII was associated with incident stroke among hypertensive middle-aged and older adults and whether this association was nonlinear. Methods We analyzed 3,823 stroke-free hypertensive participants aged 45 years or older from the China Health and Retirement Lon …

24.08.2026journal-article

The Journal of Physiology

Musculoskeletal and physiological responses to vortex wave stimulation in older adults

Alexander Waddell, Marie Korzepa, Archie E. Belfield, Ben Fry, Rickson C Mesquita, David Smith, Jonathan Quinlan, Leigh Breen

Abstract Reductions in musculoskeletal mass and function can occur with ageing and disuse. While resistance exercise training is known to minimise these detriments, it is not always feasible. Vortex wave stimulation (VWS) may mitigate skeletal muscle decline in such scenarios. The aim of the present study was to explore the acute physiological and metabolic effects of VWS in healthy older adults. Fourteen participants consumed deuterium oxide (D 2 O) stable oral isotope tracer for 7 days. Serial skeletal muscle bio …

24.08.2026journal-article

Infectious Disease Reports

Tricuspid Valve Infective Endocarditis in People Who Inject Drugs: A Single-Center Retrospective Observational Study of Percutaneous Mechanical Aspiration and a Surgical Approach

Lauren Bernard, Juliana S. Sherchan, Nazary Nebeluk, David Zapata, Murtaza Dawood, Douglas Anderson, Ramon A. Riojas, Shivakumar Narayanan

Background: People who inject drugs (PWID) comprise the majority of patients with native tricuspid valve (TV) infective endocarditis (IE). Many patients require surgical repair or replacement of their TV, but some may be deemed ineligible for surgical management due to high operative risk or patient preference. Vacuum-assisted percutaneous mechanical aspiration (PMA) has emerged as a potential alternative to surgical management in this population. The objective of this study was to describe real-world patient chara …

24.08.2026journal-article

Alzheimer's & Dementia: Behavior & Socioeconomics of Aging

Technology‐enabled educational interventions for dementia prevention: A global scoping review with a low resource settings lens

Rhedeya Nury Nodi, Emma Lea, Amy Coates, Mohammad Shoaib Hamrah, James Clement Vickers, Hannah Fair, Eddy Roccati

Abstract Dementia is rising globally, especially in low‐ and middle‐income countries (LMICs) and technology‐enabled education and related tools are potential strategies to address prevention. We synthesized the literature on technology‐enabled dementia prevention education programs worldwide with a focus on LMICs. PubMed, Scopus, Web of Science, PsycINFO, and Google Scholar were searched for primary dementia prevention studies among cognitively healthy adults. Descriptive findings were summarized. Across 37 article …

24.08.2026journal-article

International Journal of Molecular Sciences

Ginsenoside Re Attenuates D-Galactose-Induced Aging-like Oxidative Stress in Cultured Bovine Oocytes via Activation of the SIRT1/Nrf2 Signaling Pathway

Seo-Young Hyeon, Chalani Dilshani Perera, Seung-Eun Lee, Ji-Hyo Kim, Sanghwa Yoon, Yang Jae Kang, Song Park, Muhammad Idrees, Il-Keun Kong

Maternal aging is associated with increased oxidative stress and decreased mitochondrial function, which deteriorate oocyte quality. Ginsenoside Re (GRe), an antioxidant derived from Panax ginseng, has been reported to alleviate cellular damage and extend healthy lifespan. In this study, we investigated the protective effects of GRe on in vitro-matured bovine oocytes and elucidated the underlying mechanisms. Oocyte aging-like oxidative stress conditions were induced by adding 20 mg/mL D-galactose (D-gal) to the in …

24.08.2026journal-article

Frontiers in Aging Neuroscience

Target-level convergence of directional prefrontal connectivity across Alzheimer’s disease stages: an fNIRS study

Nida Mateen, Rana Muhammad Kaleem Ullah, Jisoo Baik, Keum-Shik Hong, Min-Kyoung Kang, Chang-Seok Kim, Yong-Il Shin

Background Alzheimer’s disease (AD) is increasingly recognized as involving network-level dysfunction rather than isolated regional impairment. Although functional and effective connectivity have been studied in dementia, the reorganization of directional information flow within prefrontal networks remains incompletely characterized, particularly with functional near-infrared spectroscopy (fNIRS). Objective This study investigated whether target-level convergence of directional effective connectivity within the pre …

24.08.2026journal-article

PLOS One

Tanshinone IIA attenuates cognitive impairment in vascular dementia rats by modulating copper homeostasis via the SLC31A1/FDX1 axis

Hongxiao Lv, Xinyu Yang, Yutong Liu, Junwei Zhou, Wentao Yu

Background Tanshinone IIA (TSA) is the core liposoluble active component of Salvia miltiorrhiza , a traditional Chinese medicine, and exhibits multiple pharmacological activities including anti-inflammation, anti-oxidation, anti-apoptosis and mitochondrial function improvement. Studies have confirmed that TSA can ameliorate cognitive function in rats with vascular dementia (VaD) by alleviating cerebral ischemic injury, inhibiting neuroinflammation, protecting the blood-brain barrier and other pathways. However, it …

24.08.2026journal-article

Archives of Disease in Childhood

Medicines for children and young people who seek support around gender: a horizon scanning study of the emerging medicines pipeline

Gill Norman, Ross Fairbairn, Emma Dobson, Chizoba Oparah, Ayomikun Ogunyemi, Niina Kolehmainen

Objective To provide intelligence and foresight about persistent evidence gaps in medicines for children and young people experiencing gender incongruence or dysphoria. Design A horizon scan, with foresight analysis, of clinical trial registries. Setting Global. Patients Children and young people (aged 0–17 years) experiencing gender incongruence or dysphoria. Interventions Any medicine under evaluation in an ongoing study registered on a clinical trial registry. Main outcome measures Any. Results We identified 15 …

24.08.2026journal-article

JMIR Rehabilitation and Assistive Technologies

Effects of Using a Lumbar-Type Hybrid Assistive Limb by Older Adults With Frailty on Exercise Self-Efficacy: Retrospective Analysis Based on the Kanagawa Prospective ME-BYO Cohort Study

Makoto Nagasawa, Sho Nakamura, Yoshinobu Saito, Yuko Oguma, Takashi Kasukawa, Kaname Watanabe, Hiroto Narimatsu

Abstract Background Improving exercise self-efficacy (ESE) is a key strategy for promoting sustained physical activity among older adults with frailty. The lumbar-type Hybrid Assistive Limb (HAL), a wearable device that supports voluntary movement through bioelectric signals, may facilitate mastery experiences in individuals with low baseline self-efficacy via adjustable assistance. However, its effects on ESE remain unclear. Objective This study evaluated the effects of lumbar-type HAL exercise on ESE in older adu …

24.08.2026journal-article

Environmental Research Letters

How many people live near protected areas in developing countries? Estimates from gridded population data (2000–2020)

Florent Bédécarrats

Abstract Impact evaluations of protected areas (PAs) routinely define ‘local populations’ through spatial proximity, yet the demographic scale implied by these definitions is almost never quantified. We estimate population counts inside PAs and within 10 km of their boundaries for 75 low- and lower-middle-income countries (LMICs) in 2000 and 2020, using the World Database on PAs and globally harmonized gridded population data (GHSL, with WorldPop as robustness check). India, which represents about 36% of the LMIC p …

24.08.2026journal-article

Behavioral Sciences

Better Together: Technology-Use Gaps and Loneliness in Older Adults

Ortal Cohen Elimelech, Naor Demeter, Sara Rosenblum

Loneliness is a growing public health concern among older adults, underscoring the need to better understand the complex interplay of factors associated with it. Although technology can enhance social connectedness, limited attention has been given to discrepancies between desired and actual technology use in daily life. This study examined loneliness, focusing on perceived technology-use gaps alongside health-related factors, including depressive symptoms, sleep quality, functional cognition, and sensorimotor abil …

24.08.2026journal-article

Journal of Gerontological Nursing

Community-Dwelling Older Adults' Experience With Activity Trackers: Effects of Monitoring Physical Activity

Eunice Oladepe Ojo, Victoria Loerzel, Boon Peng Ng, Rui Xie, Ladda Thiamwong

Purpose: To explore the experiences of low-income community-dwelling older adults with the physical, cognitive, sociocultural, and behavioral effects of physical activity measured with an activity tracker. Method: The current qualitative descriptive study was conducted among participants in the Physio-Feedback Exercise Program, who were aged ≥60 years and from low-income settings in Central Florida ( n = 19). A semi-structured interview guide was used to obtain participants' experiences, and the responses were tran …

24.08.2026journal-article

Journal of Gerontological Nursing

Analyzing the Effect of Nurse-Led Follow-Up Calls to Reduce Emergency Department Readmissions in Older Adults

Sarah Romanelli, Veronica Rivera, Carolina Cuervo, Leah V. Estrada

Purpose: To evaluate whether nurse-led follow-up calls after emergency department (ED) discharge were associated with decreased 30-day ED revisits and hospital admissions among older adults in two geriatric practices. Method: The current retrospective quality improvement evaluation was conducted from April 2023 to March 2025. RNs called individuals aged ≥65 years within 5 business days of ED discharge to review instructions, assess symptoms, and support primary care provider (PCP) follow up. Outcomes were 30-day ED …

24.08.2026journal-article

International Journal of Basic & Clinical Pharmacology

Drug utilization pattern of cardiovascular medications and assessment of WHO-INRUD prescribing indicators among geriatric patients in a tertiary care hospital: a cross-sectional study

Janvi A. Gandani, Snigdha Misra, Amrit Kejriwal

Background: Cardiovascular disorders are a major cause of morbidity and mortality among older patients. Drug utilization studies are useful in assessment of prescribing behaviour and rational use of drugs. To study the drug utilization pattern of cardiovascular drugs and to evaluate the prescribing practices by WHO-INRUD prescribing indicators in geriatric patients of cardiovascular illnesses admitted in tertiary care hospital. Methods: A hospital based observational cross-sectional study was carried out in Medicin …

24.08.2026journal-article

Journal of Health and Human Services Administration

Who Is Accountable for the Older Adult in Crisis? Administrative Fragmentation in Late-Life Suicide Prevention

Harish Gupta

Adults aged 75 and older recorded the highest suicide rate in the United States in 2023. Yet late-life suicide has received limited treatment in public administration as a problem of design, interagency accountability, and statutory responsibility. Drawing on the disarticulated state condition in public administration theory, this analysis, this analysis finds that authority without accountability leaves predictable handoff points unassigned across the older-adult crisis trajectory. Four federal actors contact olde …

24.08.2026journal-article

The American Surgeon™

Farm Animal-Related Trauma in an Aging Agricultural Workforce: A Multicenter Retrospective Cohort Study in Southern Appalachia

Gabriella Cote, Kalli Devecki, Keelin Roche, Sarah King, Hannah Collins, J. Bracken Burns

Agriculture remains one of the most hazardous industries in the United States, and livestock-related trauma represents an important source of injury in rural communities. As the agricultural workforce ages, understanding age-related differences in farm animal-related trauma has become increasingly important. Methods: We performed a retrospective multicenter cohort study of patients presenting with farm animal-related injuries to three regional trauma centers in Southern Appalachia between 2015 and 2024. Patients we …

24.08.2026journal-article

Transformative Society

Grey Victims Online: Older Adults Face Heightened Cyberbullying Victimization

Jinxiao Ginnie Liu, Mengxin Ding, Hongyan Lai, Chengyu Xu, Dehou You, Xinshu Zhao, Xiaoran Zhang, Dianshi Moses Li

Population ageing and rising internet use among older adults have extended digital harms across the life course. Using a stratified online survey of 2,000 adults in China, we examined cyberbullying victimization with a culturally adapted 12-item scale. Ordinary least squares regression showed a small positive association between age and victimization after adjustment for digital engagement, eHealth literacy, social isolation, and sociodemographic factors. Propensity score matching indicated that adults aged 60 year …

24.08.2026journal-article

J

Machine Learning and Deep Learning for EEG-Based Dementia Prediction: A Comprehensive Survey

Oluwatoyin Kode, Michin Hong, Long Nguyen, Soo-Yeon Ji

Dementia-related disorders, particularly Alzheimer’s disease (AD), represent a growing global health challenge, increasing the need for early and reliable detection. Electroencephalography (EEG), a non-invasive and cost-effective neurophysiological modality, has emerged as a promising tool for identifying neural signatures associated with cognitive decline. Recent advances in machine learning (ML) and deep learning (DL) have enabled more effective analysis of complex EEG signals for automated dementia prediction. T …

24.08.2026journal-article

SDÜ SAĞLIK BİLİMLERİ DERGİSİ

Retrospective Evaluation of Reasons for Ophthalmology Outpatient Visits and Diagnostic Distribution in Geriatric Patients

Kübra Erdoğan, Ayşenur Çelik

Objectives: Older adults are particularly vulnerable to ocular diseases that impair vision, quality of life, and functional independence. Understanding ophthalmology outpatient visit patterns in this population is essential for planning age-sensitive eye care services. This study aimed to analyze the primary reasons for ophthalmology outpatient visits among older adults in Turkey. Materials and Methods: Medical records of patients aged ≥65 years attending an outpatient ophthalmology clinic between January and Decem …

24.08.2026journal-article

American Journal of Physiology-Heart and Circulatory Physiology

Role of epigenetic factors during blockade of the Renin-Angiotensin system across aging

Elena MV de Cavanagh, Felipe Inserra, León Ferder

In the present article, we aimed to determine whether the beneficial effects of renin-angiotensin system (RAS) blockade on aging involve epigenetic changes and the participation of any of the cell-rejuvenating Yamanaka factors. To this end, we have reviewed published work that investigated aging and its relation to epigenetic modifications, the effects of RAS blockade on aging and epigenetics, RAS’s influence on stem cell function, and RAS interactions with the Yamanaka factors KLF4, Oct4, c-Myc, and Sox2. The revi …

24.08.2026journal-article

Revista ft

Envelhecimento facial associado ao uso da tirzepatida: alterações estéticas e estratégias de manejo na harmonização orofacial – revisão integrativa da literatura.

Adriana Karollayne Silva Pedroso, Andréia Gomes Moreira

Introduction: Tirzepatide represents an important therapeutic advance in the treatment of obesity and type 2 diabetes mellitus, promoting significant weight loss. However, this weight reduction can cause changes in facial aesthetics, popularly known as Ozempic face, characterized by volume loss, skin laxity, and accentuation of facial wrinkles, making the role of Orofacial Harmonization (OF) relevant in managing these changes. Objective: To analyze, through an integrative literature review, the main facial aestheti …