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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
23.08.2026journal-article

Social Sciences

Perceptions of Psychedelic Decriminalization: Findings from a Community Survey of People Who Use Psychedelics

Daniel J. Kruger, Julie Barron, Larry Norris

Psychedelic decriminalization has moved from the margins of drug-policy discourse to a mainstream public health and equity conversation. This community survey reveals that people with psychedelic experience who live in areas that have decriminalized psychedelics report greater benefits of psychedelic decriminalization than adverse outcomes. In decriminalized zones, most (84.0%) participants (N = 163) reported feeling improvements in one of the following areas because of decriminalization: legal risks, social accept …

23.08.2026journal-article

The American Surgeon™

The Dilemma of Prehospital Trauma Triage in Geriatric Anticoagulated Patients Sustaining Falls: Are Objective Clinical Factors Actually Helpful?

Y-Nhi H. Bui, Trevor A. Glad, Dylan M. Jack, Michael T. Martyak

Ground-level fall is a common mechanism of injury among geriatric patients taking anticoagulants. Predicting significant injury in these low mechanism injuries can be challenging. Our study investigates whether early clinical variables available to prehospital providers actually aid in this triage process. We retrospectively reviewed anticoagulated patients aged ≥65 years who sustained a ground-level fall and categorized them into two groups: (1) those requiring admission for traumatic injury and (2) those not requ …

23.08.2026journal-article

Sexualities

Older women’s later life sex and aging: Critical New Materialism (CNM) as an analytical lens

Giulia Nazzaro, Gabriëlle L de Pooter, Katrien De Graeve

This study advances sexualities studies and critical aging studies by examining the experiences of sex and intimacy in later life among older women who have faced financial precarity and violence. We argue that fully understanding women’s fragmented lives on society’s margins requires an analytical lens that highlights disrupted temporalities and the reconfiguration of time and space. We use Critical New Materialist (CNM) approaches to analyze empirical data, particularly drawing on the work of Karen Barad and Elis …

23.08.2026journal-article

International Journal of Scientific Research in Science and Technology

Smart Glove for Speech Disabled People

Ganesh Hiratot, Gauri Ingale, Vaibhav Bhujbal, Durvesh Suryavanshi, Prajakta Deshmukh

Communication is the most basic form of human interaction, yet for millions of individuals with speech and hearing impairments, it remains a significant hurdle. This project presents a "Smart Glove" designed to act as a real-time translator between manual sign language and spoken language. By employing five high-precision flex sensors (one for each finger) and a three-axis accelerometer, the system captures the intricate geometry and orientation of hand movements. These physical parameters are converted into digita …

23.08.2026journal-article

Journal of Polymer Science

Applicability of a Simple Decay Function to Describe Fire‐Protective Fabrics' Aging Behavior

Patricia I. Dolez, Kaoru Wakatsuki, Md. Saiful Hoque, Laura Munevar‐Ortiz

ABSTRACT Predicting the effect of aging conditions on materials' performance is a challenging yet critical task. In the case of fire‐protective clothing, premature performance loss may compromise end‐users' safety. Researchers have used accelerated aging to predict protective clothing's expected life. A simple decay function was recently proposed by Wakatsuki et al. to describe the effect of UV aging on the strength of para‐aramid copolymer/meta‐aramid blended fabrics. This article evidences the applicability of th …

23.08.2026journal-article

Psychogeriatrics

Perceptions of Alzheimer's Disease Among Cognitively Healthy, Community‐Dwelling Older Adults: A Metaphor Study

Tuğçe Türten Kaymaz, Güler Duru Aşiret, Arzu Yüksel

ABSTRACT Background Alzheimer's disease prevalence has risen. Although public perceptions of AD may influence attitudes toward cognitive decline and help‐seeking behaviours, little is known about how cognitively healthy older adults conceptualise the disease. This study explored older adults' metaphorical perceptions of Alzheimer's disease. Methods This qualitative study employed a phenomenological design using metaphor analysis. Participants were 196 cognitively healthy, community‐dwelling older adults. Data were …

23.08.2026journal-article

Medical Sciences

Precision Nutraceuticals and Biomarkers of Healthy Aging: A Scoping Review of Human Studies on Nutrigenomic-Based Interventions

Andrea Vanessa Llanos-Díaz, Moisés Apolaya-Segura, Orlando R. Sevillano, Obert Marín-Sanchez, Jacinto Joaquín Vértiz Osores, Alexis Germán Murillo Carrasco, Sophie Nicole Llanos-Diaz, Daysi Zulema Diaz-Obregón

Background: Precision nutrition and nutrigenomics have emerged as promising strategies to personalize dietary interventions according to individual genetic, metabolic, and molecular characteristics. However, the potential of nutrigenomic-guided nutraceutical interventions to modulate biological aging pathways remains poorly characterized. Objective: This study aimed to map and synthesize the available evidence from human studies evaluating personalized nutraceutical interventions based on nutrigenomic approaches an …

23.08.2026journal-article

Aging Cell

Metabolic Profiling of Epigenetic Aging and Its Associations With Aging‐Related Phenotypes and Modifiable Lifestyle Factors

Xunying Zhao, Tianpei Ma, Maoyao Xia, Xinyang Dui, Yangdan Zhong, Xin Chen, Yang Qu, Bowen Lei, Qingwen Zhao, Xueyao Wu, Haiyu Yan, Xingyu Zhang, Ke Jiang, Lin Hu, Lu Long, Mengyu Fan, Jiaqiang Liao, Tao Zhang, Xia Jiang, Jiayuan Li, Ben Zhang

ABSTRACT Epigenetic aging biomarkers are well‐established hallmarks of biological aging, yet their metabolic underpinnings remain largely unexplored. Here, we characterized metabolic signatures associated with five epigenetic aging biomarkers (HorvathAge, HannumAge, DNAmPhenoAge, DunedinPACE, and DNAmTL) and examined their clinical relevance and potential determinants in 7162 Chinese older adults from two cohorts (primary and validation). We observed both shared and distinct metabolic associations across epigenetic …

23.08.2026journal-article

Pharmacoepidemiology and Drug Safety

The Veterans Aging Cohort Study ( VACS )‐National: A Real‐World Data Source Profile

Christopher T. Rentsch, Vincent Lo Re, Melissa Skanderson, Kathleen A. McGinnis, Farah Kidwai‐Khan, Charles Alcorn, Anne C. Black, Kristina Crothers, Vincent C. Marconi, Matthew J. Freiberg, Jessie Torgersen, Amy C. Justice, William C. Becker, Lesley S. Park

ABSTRACT The Veterans Aging Cohort Study (VACS)‐National is a large, longitudinal real‐world data resource derived from electronic health records within the Department of Veterans Affairs (VA), the largest integrated healthcare system in the United States. As of December 2025, VACS‐National includes > 14.9 million Veterans who have received care in the VA since 2000. It captures information on VA‐related outpatient and inpatient care and includes structured (e.g., diagnostic codes, laboratory results, vital signs, …

23.08.2026journal-article

Angewandte Chemie

100‐Fold Reductivity Enhancement of Nanoscale Zero‐Valent Iron After 1‐Year Aging in Water via Regulating Corrosion Reactions

Yirong Wang, Yi Luan, Zhaowei Huang, Jiang Xu, Daohui Lin, Kun Yang, Wenhao Wu

ABSTRACT Nanoscale zero‐valent iron (nZVI) is the most promising reductant for in situ groundwater remediation, but its field application around the world is quite limited for decades, due to significant reductivity loss by water oxidation during long‐term (e.g., years) application. Herein, we report a polysiloxane(Fe)‐modified nZVI (PSO(Fe)‐nZVI, 269.0 ± 23.5 nm) featuring loosened hydrophobic C16 chains and Si─O groups on the surface and interior. Remarkably, after 420‐day aging in water, PSO(Fe)‐nZVI exhibits 10 …

23.08.2026journal-article

Bioengineering

Long-Term Air Pollution Exposure, Cardiovascular Disease, and Cardiometabolic Risk Factors in Middle-Aged and Older Chinese Adults: A Prospective Cohort Study

Xuehua Wang, Zhaohui Wang, Yan Wang

The substantial burden of cardiovascular disease (CVD) attributable to air pollution remains a critical public health challenge, yet its combined effect with cardiometabolic factors is not fully understood. This study leveraged data from the Global Burden of Disease Study (GBD) and the China High Air Pollutants (CHAP) database to evaluate the CVD burden attributable to air pollution, which was found to increase progressively with age. We conducted a cross-sectional analysis using baseline (2011) data from 7420 part …

23.08.2026journal-article

Basic & Clinical Pharmacology & Toxicology

The Feasibility and Acceptability of a Collaborative Deprescribing Intervention to Reduce Anticholinergic Burden Among Hospitalised Older Patients

Kinda Ibrahim, Eloise Radcliffe, Edward Hewertson, Andrew Bates, Andy Fox, Emily Smith, Cathrine Mckenzie, Liam Jones, Sara Mckelvie, Ngianga Ii Kandala, Sara McCloskey, Tracey Sach, Stephen Lim

ABSTRACT Introduction 37%–48% of older patients receive anticholinergic medicines, increasing the risk for falls, delirium, dementia and death. Hospital admission may provide an opportunity for deprescribing to improve outcomes. This study evaluated the feasibility and acceptability of a digital tool to identify anticholinergic medicines and support deprescribing. Methods A pre‐post feasibility study was conducted (May–September 2025). Patients aged ≥ 75 with an ACB score of ≥ 3, screened using a digital tool, were …

23.08.2026journal-article

Advances in Communication and Swallowing

Swallowing Rehabilitation in People With Spinal Muscular Atrophy: A Scoping Review

Sofia Gandolfi, Chiara Andriani, Éadaoin Flynn, Margaret Walshe

Spinal muscular atrophy (SMA) is a neuromuscular disorder associated with motor, respiratory, and swallowing impairment. This scoping review aimed to explore how swallowing rehabilitation programmes and outcomes have been reported and measured in people with SMA. The Preferred Reporting Items for Systematic reviews and Meta-Analysis extension for Scoping Reviews guidelines and the Joanna Briggs Institute three-step search strategy were followed. Five electronic databases (Embase, CINAHL Complete, PubMed, Web of Sci …

23.08.2026journal-article

Social Science Review

Perceived Effect of the Old Age Allowance on the Well-being of Older Persons in Bangladesh

Shuvashis Kumar Rimon, Md. Mahir Faysal

The Old Age Allowance Program (OAAP) provides cash aid to support impoverished older persons, which is important for ensuring their well-being. The present study examined the positive effect of the Old Age Allowance (OAA) on the well-being of older persons in Bangladesh, as perceived by both beneficiaries and non-beneficiaries. The study also explored the factors that contribute to a perceived positive effect among allowance beneficiaries. A cross-sectional study was conducted among 309 older individuals, comprisin …

23.08.2026journal-article

People and Nature

Exploring more‐than‐human ethics and the digital dimensions of nature recovery through an interactive fiction game

Leah Govia, Roberta Hawkins, Eric Nost, Jennifer J. Silver

Abstract This perspective piece considers how a more‐than‐human approach to ethics can foster nuanced, critical understandings of the digital dimensions of nature recovery. A more‐than‐human approach expands on who or what is included as ethical actors while focusing on the interconnectedness of human and nonhuman experiences. First, we discuss what more‐than‐human ethics involve, the opportunities they provide for analysis and practice, as well as what limitations in dominant approaches to nature recovery they can …

23.08.2026journal-article

ACS Omega

Understanding and Managing Phase Instability and Aging Reactions of Coalgae Pyrolysis Oils

Olwethu Poswayo, Tendai Dembaremba, Adeniyi Ogunlaja, Gary Dugmore, Zenixole Tshentu

Abstract South Africa greatly suffers from the accumulation of waste coal fines due to its heavy reliance on coal mining. The processing of pyrolysis oil ensures the beneficiation of waste coal fines to provide alternative sustainable fuels. However, phase separation and aging reactions affect the stability of the pyrolysis oils negatively, affecting their processing and the product yields and quality. Understanding and managing the stability of Coalgae pyrolysis oil remain gaps to resolving this issue, and as such …

23.08.2026journal-article

Journal of Esthetic and Restorative Dentistry

Translucency Changes of Ceramic Veneers After Aging When Cemented on Substrates With Different Saturation: Effect of Ceramic Translucency and Resin Cement Shade

Samara Franco da Silva, Camila Pontes Custódio, Paulo Francisco Cesar, Carlos Eduardo Francci

ABSTRACT Objective To evaluate the effect of ceramic translucency and resin cement shade on the translucency alteration after aging over different substrates. Methods Sixty specimens were divided into 12 groups ( n = 5) composed of lithium disilicate (IPS e.max CAD, Ivoclar Vivadent) in three translucencies (HT, MT, LT). The 0.5 mm thick specimens were cemented with Variolink Esthetic LC (Ivoclar Vivadent) Light+ (L+) and Neutral (N) over resin substrates A1 and A4. Samples were subjected to 20,000 aging thermocycl …

23.08.2026journal-article

British Journal of Occupational Therapy

An exploration into how people living in secure hospitals experience work

Joshua Ige, Jacqueline Parkes, Tracey Redwood

Introduction: This study examines how people living in secure hospitals experience work. Work is widely recognised as a vital element in mental health rehabilitation, providing structure, purpose, and opportunities for personal growth. However, engaging in work within secure hospital settings is often more complex due to environmental restrictions and their diverse needs. Methodology: Using a descriptive phenomenological approach, the study explored the lived experiences of seven individuals in secure hospitals who …

23.08.2026journal-article

Journal of Evidence-Based Community Health

Hypertension Self-Management Knowledge Before and Immediately After a Community Education Program Among Older Adults Attending a Posyandu

Novita Leony Ruhukael, Abdul Thalib, Nadira Pattimura, Lintje Sintje Corputty, Nova Bugis, Siti Nurhidayati

Hypertension requires sustained day-to-day management, but a brief community education program can directly evaluate only the outcomes it measures. This community service program described the immediate change in hypertension self-management knowledge among older adults in Suli Village, Central Maluku. Fifteen older adults were recruited through invitations at the Posyandu Lansia and participated voluntarily. The intervention consisted of one face-to-face education session delivered through an oral presentation sup …

23.08.2026journal-article

Aging Cell

Creb3l1 Overexpression Improves Flexor Tendon Repair in Aged Rats

Qian Qian Yang, Zhanghao Huang, Yan Xue, Jia Yu Shi, You Lang Zhou

ABSTRACT Aging increases tendon injury incidence and poor repair outcomes, but age‐related differences in tendon mechanical properties and underlying mechanisms remain unclear. We first analyzed data from the Global Burden of Disease (GBD) database to characterize the associations between aging and population‐level changes in tendon injury burden. We found the age‐standardized incidence rate (ASIR) of tendon injuries caused by mechanical force decreased with advancing age, whereas the age‐standardized prevalence ra …

23.08.2026journal-article

American Journal of Hematology

Older Age, STAG2 , and DNMT3A Mutations Predict Superior Posttransplant Survival in Newly Diagnosed Acute Myeloid Leukemia Treated With Venetoclax Plus Hypomethylating Agents

Momna Warraich, Sudhesh Kumar, Mahnoor Fatima, Kristen McCullough, Aref Al‐Kali, Hassan B. Alkhateeb, Kebede H. Begna, Abhishek Mangaonkar, Antoine N. Saliba, Aasiya Matin, Mark R. Litzow, William Hogan, Mithun V. Shah, Mrinal M. Patnaik, Animesh Pardanani, James Foran, Lisa Sproat, Nandita Khera, Ayalew Tefferi, Naseema Gangat

ABSTRACT Venetoclax (Ven) plus hypomethylating agents (HMA) is standard frontline therapy for newly diagnosed AML (ND‐AML) patients unfit for intensive chemotherapy and is also considered in younger, fit patients. However, consolidation with allogeneic stem cell transplant (ASCT) is often required to secure durable remission. The current study examines posttransplant outcomes in patients with ND‐AML treated with frontline Ven‐HMA who subsequently underwent ASCT. A total of 111 ND‐AML patients (58% male, 60% seconda …

23.08.2026journal-article

Diabetes, Obesity and Metabolism

Variation in Treatment Patterns of Type 2 Diabetes in Older Patients

Phuc Le, Ning Guo, Anita Misra‐Hebert, Christopher B. Boyer, Kevin M. Pantalone, Hamlet Gasoyan, Nicholas J. Casacchia, Michael B. Rothberg

ABSTRACT Aims To estimate the proportion of older patients with type 2 diabetes (T2D) and HbA1c above or below goal at provider level and explore factors associated with patients being above or below goal. Materials and Methods We used 2023 Cleveland Clinic electronic health records, including patients ≥ 65 years old with T2D, ≥ 1 diabetes medication and ≥ 1 HbA1c measurement. Patients were assigned to their listed primary care provider or the one they saw most frequently and stratified into good, intermediate, or …

22.08.2026journal-article

Scientific Reports

Carotid plaque burden and hemodynamic alterations are associated with domain-specific cognitive impairment in community-dwelling older adults

Ahmed Elhfnawy, Mohamed Saud Kishk, Hany El Deeb, Jaidaa Mekky

Abstract Carotid atherosclerosis has been linked to cognitive decline, but evidence regarding its association with domain-specific cognitive performance in understudied non-Western populations remains limited. We investigated the associations of carotid plaque burden and hemodynamic markers with cognitive impairment in 100 community-dwelling Egyptian adults aged ≥ 60 years without prior neurological disease. Carotid plaque burden was quantified by duplex ultrasound using plaque score, and cognition was assessed usi …