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22 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Frontiers in Public Health

Experiences of death preparedness among family caregivers of terminal patients: a systematic review and meta-synthesis

Xinyu Ju, Yujin Zhang, Xiaosong Wang, Qiong Lu, Yuan Li, Jinhua Hong

Background Death preparedness is an important component of hospice care, yet research focusing on family caregivers of terminally ill patients remains in its early stages, with few studies systematically synthesizing the death preparedness experiences of this group. The study aimed to integrate the experiences of death preparedness among family caregivers of terminally ill patients and provide a reference for developing family-centered supportive care interventions for this population. Methods A systematic review a …

28.08.2026journal-article

American Journal of Health-System Pharmacy

Moving beyond a tale of two genes: Strides in management of metastatic gastrointestinal stromal tumors and their supportive care

Clement Chung, Anthony Albayeh

Abstract Purpose This article evaluates and summarizes key therapeutic advances and supportive care considerations for metastatic gastrointestinal stromal tumors (GISTs). Summary GISTs comprise a highly aggressive, heterogeneous group of soft tissue sarcomas that span multiple anatomic origins. Following surgical resection, GISTs often recur locally or metastasize to the liver. Collectively, GISTs represent the first group of solid malignancies that was elucidated as a mutation-driven neoplasm more than 2 decades a …

28.08.2026journal-article

Akdeniz Hemşirelik Dergisi

Studies on Patient Empowerment in Nursing in Türkiye: A Content Analysis of Postgraduate Theses

Şeyma Demir Erbaş, Elif Gençer Şendur

Aim Patient-centered care in healthcare requires patients to be more involved in decision-making processes and to have more control over their own health. This promotes patient empowerment initiatives. The purpose of this study is to examine postgraduate theses based on patient empowerment conducted in the field of nursing in Türkiye. Methods The study was conducted based on the descriptive content analysis of data obtained from postgraduate theses. The National Thesis Center database of the Council of Higher Educa …

28.08.2026journal-article

European Journal of Clinical Microbiology & Infectious Diseases

Selective statin therapy and nasal staphylococcal colonisation: a retrospective case-control study

Zahraa Abbas, Jeffery Hughes, Bruce Sunderland, Richard Parsons, Matthew Rawlins, Owen Robinson, Petra Czarniak

Abstract Background Nasal Staphylococcus aureus ( S. aureus ) colonisation is a key risk factor for serious infections. Statins, used for hypercholesterolaemia and cardiovascular disease prevention, have been linked to gut microbiome dysbiosis, but their impact on nasal bacterial colonisation remains unclear. Purpose To examine whether statin use, individual statins, and statin dose intensity are associated with nasal S. aureus colonisation, and whether associations differ between methicillin-sensitive S. aureus (M …

28.08.2026journal-article

Structural Health Monitoring

Structural damage identification of wind turbine blades based on multi-scale deformable linear Transformer network

Zhitai Xing, Bohua Chen, Aijun Hu, Xinghua Yuan, Ling Xiang

Structural damage identification of wind turbine blades (WTBs) is crucial for reducing maintenance costs and ensuring operational reliability. Data-driven methods leveraging supervisory control and data acquisition (SCADA) data have advanced WTBs monitoring, but existing approaches remain limited by models that fail to capture subtle changes in blade damage characteristics. To address these gaps, a novel multi-scale deformable linear Transformer network (MDLTN) is proposed for structural damage identification of WT …

28.08.2026journal-article

Clinics and Practice

Clinical Relevance of Calcifications in Osteosarcoma Lung Metastases: Correlations Among Radiological Patterns, Histological Subtypes, and Chemotherapy Responses

Paolo Spinnato, Mario Simonetti, Maria Carpenzano, Gabriele Bilancia, Nicola Marrone, Annamaria Chiesa, Maddalena Di Carlo, Emanuela Palmerini, Luca Cevolani, Marco Colangeli, Marco Gambarotti, Alberto Righi, Alessandra Longhi

Background/Objectives: Osteosarcoma is a rare malignancy and the most common primary malignant bone tumor. Metastases commonly affect the lungs and are associated with reduced life expectancy. Calcifications can be present within a metastatic nodule at baseline or can appear during follow-up. We aimed to assess the clinical significance of calcifications in lung metastases, particularly in relation to radiological pattern, histopathological subtype, and treatment response. Methods: A retrospective cohort of patient …

28.08.2026journal-article

Advances In Social Humanities Research

Assessing The Severity of Oropharyngeal Dysphagia and its Relation to Quality of Life Status in Head and Neck Cancer Patients After Undergoing Chemoradiotherapy in DR Sardjito Public Hospital, Yogyakarta, Indonesia: A Cross Sectional Prospective Study

Anisa Haqul Khoiria, Agus Surono, Camelia Herdini

Head and neck cancer treatment frequently causes oropharyngeal dysphagia, which may impair nutritional status, psychological well-being, social functioning, and overall quality of life. This study aimed to assess dysphagia severity and swallowing-related quality of life, compare changes in these outcomes during early follow-up, and determine the relationship between dysphagia severity and quality of life among patients after chemoradiotherapy. A prospective observational study was conducted among 60 patients with h …

28.08.2026journal-article

Odovtos - International Journal of Dental Sciences

Effects of Surgical and Non-surgical Periodontal Therapy on Renal Function and Inflammatory Biomarkers and Mortality in Patients with Chronic Kidney Disease: An Umbrella Review

Anny Marcela Vivares-Builes, María Teresa Pertúz-Rondón, German Márquez-Toro, Carlos Pizarro-Herrera, Andrés Alonso Agudelo-Suarez, Carlos M. Ardila

Periodontitis and chronic kidney disease (CKD) share common pathophysiological mechanisms, with periodontitis acting as a chronic inflammatory comorbidity that exacerbates systemic inflammation in CKD patients. This study aimed to analyze the effect of surgical and non-surgical periodontal therapy on renal function, inflammatory biomarkers, and mortality in patients with CKD according to the available evidence. An umbrella review was conducted, including systematic reviews and meta-analyses from databases such as P …

28.08.2026journal-article

Education in Medicine Journal

Correlations Between Master Adaptive Learners’ Characteristics and Anatomy Performance in an Active and Gamebased Anatomy Learning

Asty Amalia Nurhadi, Budu, Andi Alfian Zainuddin, Ichlas Nanang Afandi, Haerani Rasyid, Irawan Yusuf, Irfan Idris, Indang Ariati Arifin, Lelimiska Irmadani Syarif, Gita Vita Soraya

Master Adaptive Learners (MALs) can adjust their learning strategies to overcome challenges, a key trait for success in complex subjects like anatomy. This study explored the correlation between MAL characteristics—curiosity, motivation, growth mindset, and resilience—and anatomy performance in an active, game-based learning environment. A cross-sectional study was conducted among 246 first-year medical students at Hasanuddin University in 2022. The anatomy course used blended, active learning, and game-based learn …

28.08.2026journal-article

Experimental and Clinical Endocrinology & Diabetes

Effects of thyroid hormones on muscle and bone in mice

Akihito Nishikawa, Naoyuki Kawao, Yuya Mizukami, Ryota Kishigami, Koji Goto, Hiroshi Kaji

Abstract Background: The significance of muscle–bone interactions in bone metabolism and the pathophysiology of osteoporosis has been recognized. However, the effects of thyroid hormones on muscle–bone interactions remain unclear. Methods: We herein investigated the effects of hyperthyroidism on muscle and bone by administering L-thyroxin to male mice for 4 weeks. Results: A micro-computed tomography analysis showed that the administration of L-thyroxin significantly decreased trabecular bone mineral density, bone …

28.08.2026journal-article

Glosains: Jurnal Sains Global Indonesia

Comparison of Low-Level and High-Intensity Laser Therapy Effects on Functional Outcomes in Knee Osteoarthritis

Fauzan Ahmad, Mohammad Barlian Nugroho, Djoko Witjaksono, Viera Wardhani

Background: Low-Level Laser Therapy (LLLT) and High-Intensity Laser Therapy (HILT) are widely used nonpharmacological interventions for patients with knee osteoarthritis (KOA). However, scientific evidence comparing the effectiveness of these two therapies on functional outcomes remains limited. Objective: To compare the effects of LLLT and HILT combined with quadriceps bench exercises on knee function, walking speed, and knee proprioception in patients with KOA. Methods: This randomized controlled trial used a pre …

28.08.2026journal-article

Journal of Health Science and Medical Research

Melioidotic Otomastoiditis in Triplets: A Rare Pediatric Cluster with Intracranial Complications

Chayanit Kritpracha, Viraporn Atchariyasathian, Pittayapon Pitathawatchai

Melioidosis, caused by Burkholderia pseudomallei (B. pseudomallei), is endemic in tropical regions, including Thailand. Often called “the great mimicker,” it can involve multiple organ systems and present with varied clinical manifestations. While the lungs are the most commonly affected site, head and neck manifestations occur in 14.0–25.0% of cases, primarily as neck abscesses or suppurative parotitis, and otologic involvement is exceedingly rare. We report a cluster of melioidotic otitis media in three 15-month- …

28.08.2026journal-article

International Journal of Social Sciences and Public Administration

The Human-Centered Narrative of Chinese Path to Modernization

Siqi Wu

Human beings are the subject of Chinese path to modernization, the emergence and development of which are oriented toward satisfying the diverse needs of the people and realizing their free and comprehensive development. Chinese path to modernization is characterized by rich theoretical connotations and a sound practical pathway, and distinctly embodies a human-centered feature: a vast population highlights subjectivity; common prosperity underscores sociality; coordination of material and spiritual civilization de …

28.08.2026journal-article

Journal of Computer Assisted Tomography

Association of Imaging-Defined Deep Invasion and Tumor Volume With Clinical Cervical Lymph Node Metastasis in Hypopharyngeal Carcinoma

Hinano Anaba, Yohei Morishita, Ryo Ishii, Takuma Usuzaki, Tomo Kinoshita, Yoshitaka Toyama, Akira Ohkoshi, Yukio Katori, Kei Takase

Objective: Deep tumor invasion is a recognized pathologic risk factor for cervical lymph node metastasis in patients with hypopharyngeal carcinoma, but the relationship between imaging findings of the primary tumor and clinical lymph node metastasis has not been fully defined. In this study, we assessed whether imaging-defined deep invasion and tumor volume are associated with clinical lymph node metastasis. Methods: This retrospective study included 142 consecutive patients with newly diagnosed hypopharyngeal squa …

28.08.2026journal-article

Nutrients

Food Noise Among Healthcare Students and Healthcare Professionals in Al-Ahsa, Saudi Arabia: A Cross-Sectional Study

Saba Alarfaj, Manal Alqahtani, Abdullah Almaqhawi

Background: Food noise describes persistent, intrusive thoughts about food, eating, and cravings that occur in the absence of physiological hunger. Its occurrence among healthcare students and professionals in Saudi Arabia is unknown. This study measured food noise in this group in Al-Ahsa, described the proportion meeting study-defined severity thresholds, and identified its main correlates. Methods: In this cross-sectional study, healthcare students and professionals in Al-Ahsa completed a bilingual (Arabic–Engli …

28.08.2026journal-article

Medicine

Causal relationship between immune factors and Guillain-Barré syndrome

Taichuan Xu, Xingguo Zhang, Xianfa Xu, Wentao Xiao, Wenjie Li, Xian Zhang

Guillain-Barré syndrome (GBS) is an immune-mediated polyneurogenic disorder that is strongly correlated with immune factors. However, causal relationships between these factors remain unclear. We used 2-sample Mendelian randomization (MR) and inverse MR analysis. Immune factors were used as the outcome for GBS exposure. Cochrane Q test was used to detect heterogeneity. Simultaneously, the MR-Egger intercept test and MR-Pleiotropy Residual Sum and Outlier tests were used to check for horizontal pleiotropy. MR Steige …

28.08.2026journal-article

Medicine

Poststroke fever etiology

Lijiang Wang, Wei Jin, Yuhua Wu, Menglu Zhu

Rationale: Piperacillin–tazobactam is a widely used antibiotic, but its adverse effects, particularly drug fever and hematological toxicities, are often underestimated. The concurrent occurrence of drug fever and agranulocytosis may complicate the differential diagnosis of persistent or recurrent fever, particularly in patients with stroke-associated pneumonia. We report a case of probable piperacillin–tazobactam–associated drug fever and agranulocytosis and review the relevant literature. Patient concerns: A 45-ye …

28.08.2026journal-article

Medicine

Perforation of the right ventricle and inferior vena cava by bone cement after percutaneous vertebroplasty

Yan Dong, Yongfeng Zhu, Zhikun Fu, Yaping Xu, Xiangli Zhang

Rationale: Percutaneous vertebroplasty (PVP) is widely used to treat vertebral compression fractures. Although it is generally considered a minimally invasive procedure, leakage and systemic migration of polymethylmethacrylate bone cement may rarely occur and can cause potentially fatal cardiovascular complications. Intracardiac bone cement embolism accompanied by perforation of the right ventricle and inferior vena cava (IVC) is particularly uncommon. Patient concerns: A 70-year-old woman presented with palpitatio …

28.08.2026journal-article

Medicine

Association between thymidine kinase 1 and clinicopathological high-risk features in breast cancer

Yanze Liu, Jiaqi Liu

Thymidine kinase 1 (TK1) is a cell-cycle-regulated enzyme involved in DNA synthesis and is closely linked to tumor cell proliferation. This study investigated whether serum TK1 concentration is associated with clinicopathological high-risk features in breast cancer (BC) and whether TK1 changes after neoadjuvant chemotherapy (NACT). This retrospective single center cohort included 410 patients with invasive BC. Serum TK1 was analyzed according to age, lymph node metastasis (LNM), histological grade, Ki-67, circulati …

28.08.2026journal-article

Medicine

The global research of artificial intelligence on Alzheimer disease

Hong-Yan Wu, Xiao-Shan Wang, Mei Yang, Jing Cai

Background: With the increasing global prevalence of Alzheimer disease (AD), there has been heightened attention on the onset and progression of AD. Studies indicate that artificial intelligence (AI) has demonstrated potential in the early prediction and diagnosis of AD. However, current research still falls short in terms of data diversity and the application of personalized models. Objective: This manuscript utilizes bibliometric methods to explore the application trends and emerging frontiers of AI in AD researc …

28.08.2026journal-article

IIARD International Journal of Banking and Finance Research

Public Debt Financing Strategies and Their Impact on Sustainable Economic Growth in Nigeria

Ogechukwuka CHEGWE

This study examines the impact of public debt financing strategies on sustainable economic growth in Nigeria between 1990 and 2024. The research employs secondary time-series data obtained from the World Bank, Debt Management Office, and Central Bank of Nigeria, analyzing the relationships between public debt indicators and economic performance. Using an econometric regression model, the study investigates how debt-to-GDP ratio, interest paymentsto-revenue, gross fixed capital formation, inflation, real interest ra …

28.08.2026journal-article

The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences

Biological Age Associates with Longitudinal Frailty-Related Functional Decline: The Health and Retirement Study

Savvina Prapiadou, Tamara N Kimball, Benjamin Y Q Tan, Reinier W P Tack, Devanshi Choksi, Marie-Gabrielle Duperron, Jasper R Senff, Evy M Reinders, Tan Li Feng, Sanjula D Singh, Jonathan Rosand, Christopher D Anderson

Abstract Epigenetic clocks have emerged as markers of biological aging. Understanding their association with age-related functional decline may provide insights into DNA-mediated mechanisms underlying frailty-related functional decline and reveal which clocks best associate with accelerated functional decline. We therefore examined associations between established epigenetic clock measures and longitudinal trajectories of cognitive function, grip strength, and walking speed. We analyzed data from 4,018 participants …