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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Clinical Medicine and Pharmacology

Clinical case of pernicious anemia

V. Arhipenko

Vitamin B12 - deficiency anemia (pernicious anemia, Addison-Biermer disease) – megaloblastic anemia, arising due to the deficiency of cyanocobalamin in the body, characterized by impaired erythropoiesis, damage to the hematopoietic tissue, digestive and nervous systems. Presented modern data on epidemiology, etiology, pathogenesis, diagnosis and treatment of vitamin B12-deficiency anemia based on clinical guidelines. Special attention is paid to the role of autoimmune mechanisms in the development of the disease an …

28.08.2026journal-article

Movement Disorders Clinical Practice

Clinically Probable REM Sleep Behavior Disorder and Other Non‐Motor Symptoms in Progressive Supranuclear Palsy: Prevalence and Associated Clinical Features

Neeraj Balaini, Paras Borse, Manu Santhappan Girija, Reji Paul, Aimy Hynse, Asha Kishore

Abstract Background REM sleep behavior disorder (RBD) is now increasingly recognized in progressive supranuclear palsy (PSP), with unclear clinical relevance. Objectives To determine the frequency of pRBD and non‐motor symptoms in PSP and association between the two. Methods We enrolled 150 consecutive patients with PSP and 150 age‐ and sex‐matched controls. Probable RBD (pRBD) was identified using the REM Sleep Behavior Disorder Screening Questionnaire. Clinical, cognitive, and NMS scores were measured using valid …

28.08.2026journal-article

Occupational Medicine

Nutrition and hydration habits of German anaesthesiology residents

J Reuter, P Meybohm, J Menger

Abstract Background Adequate nutrition and hydration during clinical workdays are essential for physicians’ wellbeing, health, cognitive function, and performance. Anaesthesiology residents work in high-pressure environments that may hinder adherence to recommended dietary and fluid intake guidelines and impair their healthy eating and drinking habits. Aims To assess the dietary and hydration habits of anaesthesiology residents in Germany, identify workplace-related barriers, and evaluate their readiness for behavi …

28.08.2026journal-article

Borneo Nursing Journal (BNJ)

Kesiapan Menyusui pada Ibu Hamil Trimester III di Wilayah Kerja Puskesmas Pemurus Baru

Maya Safitri, Nurul Hidayah, Yuni Riska Nur Fariana, Dwi Sogi Sri Redjeki

Latar Belakang: Trimester Ketiga merupakan periode krusial bagi ibu hamil untuk mempersiapkan pemberian ASI eksklusif. Capaian ASI eksklusif di Kalimantan Selatan 66,01%, masih dibawah target nasional 80%. Rendahnya kesiapan terutama pada aspek psikologis berpotensi menghambat keberhasilan menyusui. Tujuan: Mengetahui kesiapan menyusui pada ibu hamil trimester III di wilayah kerja Puskesmas Pemurus Baru. Metode: Penelitian deskritif kuantitatif, dengan teknik sampling pengambilan sampel menggunakan total sampling. …

28.08.2026journal-article

Frontiers in Medicine

Clinical benefit without sweat chloride response after ETI therapy in an adult with cystic fibrosis bearing the L467F;F508del complex CFTR allele: a case report and the role of AI-assisted chest CT in longitudinal monitoring

Marcela Kreslova, Daan Caudri, Isabelle Sermet-Gaudelus, Aurelie Hatton, Punitkumar Makani, Vaclav Koucky, Malgorzata Libik, Hana Hrdinova, Libor Fila, Nela Stastna, Eva Furstova, Radka Bittenglova, Jan Baxa, Josef Sykora, Milan Macek

Background Elexacaftor/tezacaftor/ivacaftor (ETI) is the standard of care for most people with cystic fibrosis (CF) who carry at least one F508del allele. However, predicting responses to CFTR modulators in rare or complex CFTR genotypes is challenging. Sweat chloride concentration (SCC) and patient-derived functional assays assessing CFTR-mediated chloride transport are commonly used to classify modulator responsiveness. Carriers of the p.Leu467Phe;p.Phe508del (henceforward legacy nomenclature: L467F;F508del) comp …

28.08.2026journal-article

Frontiers in Public Health

Experiences of death preparedness among family caregivers of terminal patients: a systematic review and meta-synthesis

Xinyu Ju, Yujin Zhang, Xiaosong Wang, Qiong Lu, Yuan Li, Jinhua Hong

Background Death preparedness is an important component of hospice care, yet research focusing on family caregivers of terminally ill patients remains in its early stages, with few studies systematically synthesizing the death preparedness experiences of this group. The study aimed to integrate the experiences of death preparedness among family caregivers of terminally ill patients and provide a reference for developing family-centered supportive care interventions for this population. Methods A systematic review a …

28.08.2026journal-article

Journal of Health Science and Medical Research

Melioidotic Otomastoiditis in Triplets: A Rare Pediatric Cluster with Intracranial Complications

Chayanit Kritpracha, Viraporn Atchariyasathian, Pittayapon Pitathawatchai

Melioidosis, caused by Burkholderia pseudomallei (B. pseudomallei), is endemic in tropical regions, including Thailand. Often called “the great mimicker,” it can involve multiple organ systems and present with varied clinical manifestations. While the lungs are the most commonly affected site, head and neck manifestations occur in 14.0–25.0% of cases, primarily as neck abscesses or suppurative parotitis, and otologic involvement is exceedingly rare. We report a cluster of melioidotic otitis media in three 15-month- …

28.08.2026journal-article

Frontiers in Medicine

Early diagnosis and therapy of Chlamydia psittaci pneumonia: insights from chest CT, tNGS, and omadacycline in 34 cases

Qiuting Jiang, Xiaoli Zhao, Yuan Zhu, Xinmin Zhu, Shaohua Hu, Huajuan Zhou

Objective This study retrospectively analyzed the clinical characteristics and management strategies of 34 patients with Chlamydia psittaci pneumonia. We aimed to evaluate the diagnostic value of subpleural-predominant pulmonary CT manifestations combined with bronchoalveolar lavage fluid targeted next-generation sequencing (tNGS), and to assess the clinical efficacy and therapeutic advantages of omadacycline in this patient cohort. Methods Clinical data were retrospectively collected from patients diagnosed with C …

28.08.2026journal-article

Frontiers in Medicine

Exercise adherence and wrist function recovery after distal radius fracture surgery in older adults: a 12 week prospective longitudinal study

Sunan Ji, Yiping Sun, Yu Zhu

Objective To explore the interactive relationship between wrist function recovery trajectory and exercise adherence in older patients after surgical treatment of distal radius fractures. Methods This study was a prospective, multicenter, observational study. A total of 230 older patients with distal radius fractures who underwent volar locking plate internal fixation at Nantong Sixth People's Hospital and Affiliated Hospital of Nantong University from February 2025 to February 2026 were enrolled. Wrist function was …

28.08.2026journal-article

F1000Research

Father Absence and Masculinity Formation Among Young Men: A Public Practical Theological Exploration of Emotional Development and Relational Identity

Thalukanyo Cloepatra Mufunwa Sadiki, Lufuluvhi maria Mudimeli

Background The lack of a father figure poses a significant challenge not only for society but also for how boys form their own identity through emotion and personal growth. While there has been a large amount of research published on how boys form masculinity based on behaviour and social constructs, there is limited empirical research that has examined men’s masculine identity from a public perspective of practical theology. Methods Nevertheless, this study’s qualitative desktop methodology will draw on available …

28.08.2026journal-article

Lombok Medical Journal

<b>Virtual Reality Therapy as an Innovative Intervention in Mental Health: A Literature Review</b>

Afra Ruchudinia Mufida, Aisyah Adinda Kurniawan, Diska Aprisa Lestari, Eprel Pranacinsa Tanagan, Azizatul Adni

The advancement of digital technology has driven innovation in mental health interventions, including Virtual Reality Therapy (VRT), a technology-based approach that enables patients to experience immersive and controlled three-dimensional environments. This literature review aims to examine the concepts and effectiveness of VRT in managing mental health disorders. The findings indicate that VRT is effective in reducing symptoms of anxiety, depression, post-traumatic stress disorder (PTSD), and substance use disord …

28.08.2026journal-article

Frontiers in Pediatrics

Development and temporal validation of a postoperative nomogram based on clinical, surgical, histopathological, and semi-quantitative EEG features for predicting seizure-free survival in children after focal epilepsy surgery

Xiaoyan Dong, Ting Sun

Objective Accurate estimation of seizure recurrence risk after pediatric epilepsy surgery may support individualized postoperative surveillance and management. This study aimed to develop and temporally validate a prognostic nomogram for estimating 1-year and 2-year seizure-free survival after focal or lobar resection in children with drug-resistant epilepsy. Methods This single-center retrospective cohort study included 256 children treated between 2015 and 2024. Patients treated during 2015–2021 constituted the t …

28.08.2026journal-article

Glosains: Jurnal Sains Global Indonesia

Comparison of Low-Level and High-Intensity Laser Therapy Effects on Functional Outcomes in Knee Osteoarthritis

Fauzan Ahmad, Mohammad Barlian Nugroho, Djoko Witjaksono, Viera Wardhani

Background: Low-Level Laser Therapy (LLLT) and High-Intensity Laser Therapy (HILT) are widely used nonpharmacological interventions for patients with knee osteoarthritis (KOA). However, scientific evidence comparing the effectiveness of these two therapies on functional outcomes remains limited. Objective: To compare the effects of LLLT and HILT combined with quadriceps bench exercises on knee function, walking speed, and knee proprioception in patients with KOA. Methods: This randomized controlled trial used a pre …

28.08.2026journal-article

Clinics and Practice

Clinical Relevance of Calcifications in Osteosarcoma Lung Metastases: Correlations Among Radiological Patterns, Histological Subtypes, and Chemotherapy Responses

Paolo Spinnato, Mario Simonetti, Maria Carpenzano, Gabriele Bilancia, Nicola Marrone, Annamaria Chiesa, Maddalena Di Carlo, Emanuela Palmerini, Luca Cevolani, Marco Colangeli, Marco Gambarotti, Alberto Righi, Alessandra Longhi

Background/Objectives: Osteosarcoma is a rare malignancy and the most common primary malignant bone tumor. Metastases commonly affect the lungs and are associated with reduced life expectancy. Calcifications can be present within a metastatic nodule at baseline or can appear during follow-up. We aimed to assess the clinical significance of calcifications in lung metastases, particularly in relation to radiological pattern, histopathological subtype, and treatment response. Methods: A retrospective cohort of patient …

28.08.2026journal-article

Annals of Surgical Oncology

Prospective Clinical Trial on Expanding the Eligibility Criteria for Targeted Axillary Dissection after Neoadjuvant Systemic Therapy in Breast Cancers with Advanced Nodal Disease

A. J. T. Lee, B. H. H. Cheung, D. T. K. Suen, A. Kwong

Abstract Background Targeted axillary dissection (TAD) is an established axillary restaging approach in breast cancer after neoadjuvant chemotherapy (NAC), but evidence to date has focused largely on clinical N1 disease with limited nodal involvement. For higher nodal burden patients, axillary dissection (AD) is still frequently performed despite high axillary pathologic complete response (pCR) rates. We hypothesized that TAD is noninferior to AD for nodal staging in patients with advanced nodal disease. Patients a …

28.08.2026journal-article

European Journal of Clinical Microbiology & Infectious Diseases

Selective statin therapy and nasal staphylococcal colonisation: a retrospective case-control study

Zahraa Abbas, Jeffery Hughes, Bruce Sunderland, Richard Parsons, Matthew Rawlins, Owen Robinson, Petra Czarniak

Abstract Background Nasal Staphylococcus aureus ( S. aureus ) colonisation is a key risk factor for serious infections. Statins, used for hypercholesterolaemia and cardiovascular disease prevention, have been linked to gut microbiome dysbiosis, but their impact on nasal bacterial colonisation remains unclear. Purpose To examine whether statin use, individual statins, and statin dose intensity are associated with nasal S. aureus colonisation, and whether associations differ between methicillin-sensitive S. aureus (M …

28.08.2026journal-article

Structural Health Monitoring

Structural damage identification of wind turbine blades based on multi-scale deformable linear Transformer network

Zhitai Xing, Bohua Chen, Aijun Hu, Xinghua Yuan, Ling Xiang

Structural damage identification of wind turbine blades (WTBs) is crucial for reducing maintenance costs and ensuring operational reliability. Data-driven methods leveraging supervisory control and data acquisition (SCADA) data have advanced WTBs monitoring, but existing approaches remain limited by models that fail to capture subtle changes in blade damage characteristics. To address these gaps, a novel multi-scale deformable linear Transformer network (MDLTN) is proposed for structural damage identification of WT …

28.08.2026journal-article

Education in Medicine Journal

Correlations Between Master Adaptive Learners’ Characteristics and Anatomy Performance in an Active and Gamebased Anatomy Learning

Asty Amalia Nurhadi, Budu, Andi Alfian Zainuddin, Ichlas Nanang Afandi, Haerani Rasyid, Irawan Yusuf, Irfan Idris, Indang Ariati Arifin, Lelimiska Irmadani Syarif, Gita Vita Soraya

Master Adaptive Learners (MALs) can adjust their learning strategies to overcome challenges, a key trait for success in complex subjects like anatomy. This study explored the correlation between MAL characteristics—curiosity, motivation, growth mindset, and resilience—and anatomy performance in an active, game-based learning environment. A cross-sectional study was conducted among 246 first-year medical students at Hasanuddin University in 2022. The anatomy course used blended, active learning, and game-based learn …

28.08.2026journal-article

American Journal of Health-System Pharmacy

Moving beyond a tale of two genes: Strides in management of metastatic gastrointestinal stromal tumors and their supportive care

Clement Chung, Anthony Albayeh

Abstract Purpose This article evaluates and summarizes key therapeutic advances and supportive care considerations for metastatic gastrointestinal stromal tumors (GISTs). Summary GISTs comprise a highly aggressive, heterogeneous group of soft tissue sarcomas that span multiple anatomic origins. Following surgical resection, GISTs often recur locally or metastasize to the liver. Collectively, GISTs represent the first group of solid malignancies that was elucidated as a mutation-driven neoplasm more than 2 decades a …

28.08.2026journal-article

Advances In Social Humanities Research

Assessing The Severity of Oropharyngeal Dysphagia and its Relation to Quality of Life Status in Head and Neck Cancer Patients After Undergoing Chemoradiotherapy in DR Sardjito Public Hospital, Yogyakarta, Indonesia: A Cross Sectional Prospective Study

Anisa Haqul Khoiria, Agus Surono, Camelia Herdini

Head and neck cancer treatment frequently causes oropharyngeal dysphagia, which may impair nutritional status, psychological well-being, social functioning, and overall quality of life. This study aimed to assess dysphagia severity and swallowing-related quality of life, compare changes in these outcomes during early follow-up, and determine the relationship between dysphagia severity and quality of life among patients after chemoradiotherapy. A prospective observational study was conducted among 60 patients with h …

28.08.2026journal-article

Izmir Katip Celebi University Faculty of Medicine

ANALYSIS OF TRIAGE CODE AND DIAGNOSIS DISTRIBUTIONS OF PATIENTS ARRIVING VIA 112 EMERGENCY SERVICES

Emre Kahveci, Zehra Aldemir, Mazlum Aslan, Berivan Ağaoğlu, Ejder Saylav Bora

ABSTRACT Objective: The aim of this study is to interpret the use of 112 emergency medical services by revealing the demographic characteristics, triage code and diagnosis distributions, and outcomes of patients who arrived at a training and research hospital via 112. Method: This study retrospectively examined patients who arrived at the emergency department of İKÇÜ Atatürk Training and Research Hospital by ambulance between January 1 and December 31, 2024, using the hospital information system. Patients with inco …

28.08.2026journal-article

IIARD International Journal of Banking and Finance Research

Public Debt Financing Strategies and Their Impact on Sustainable Economic Growth in Nigeria

Ogechukwuka CHEGWE

This study examines the impact of public debt financing strategies on sustainable economic growth in Nigeria between 1990 and 2024. The research employs secondary time-series data obtained from the World Bank, Debt Management Office, and Central Bank of Nigeria, analyzing the relationships between public debt indicators and economic performance. Using an econometric regression model, the study investigates how debt-to-GDP ratio, interest paymentsto-revenue, gross fixed capital formation, inflation, real interest ra …