Frag' FlorenceEvidenz. Klar. Anwendbar.
Uhr 7/8Sources Journal Tree
Easy Demo

Florence Themenbrowser · Alter & Demenz · Seite 27

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
21.08.2026journal-article

Metabolites

Ciliary Neurotrophic Factor in Skeletal Muscle of Older Adults and the Effects of Weight Loss and Aerobic Training

Alice S. Ryan, Guoyan Li, Colleen Lynch, Sausan M. Jaber, Galya Bigman

Background/Objectives: Ciliary neurotrophic factor (CNTF), a pleiotropic cytokine with central and peripheral actions, has been implicated in obesity, insulin resistance, and aging, yet its role in skeletal muscle and cardiometabolic health remains unclear. This study examined skeletal muscle CNTF mRNA expression in relation to adiposity and glucose tolerance in older adults and assessed the effects of six-month weight loss (WL) and aerobic exercise training (AEX) interventions on its expression. Methods: Sixty-sev …

21.08.2026journal-article

JAIDS Journal of Acquired Immune Deficiency Syndromes

Breaking the Chain: HIV-1 Transmission Clusters among People who Inject Drugs in North Carolina, 2010 to 2023

Theppharit Panichsillapakit, Cara J. Broshkevitch, Kimberly Enders, Annalea Greifinger, Shuntai Zhou, Simon D.W. Frost, Erik Volz, Joseph J. Eron, Victoria Mobley, Erika Samoff, Ann M. Dennis

Background: Injection drug use (IDU) remains a major mode of HIV transmission in the United States, with rising use putting more people who inject drugs (PWID) at risk for HIV. Understanding HIV transmission clusters in this population can inform public health outreach strategies. We examined factors associated with linkage to HIV clusters among PWID in North Carolina (NC). Setting: NC maintains a statewide molecular HIV surveillance system, enabling identification of transmission clusters across diverse urban and …

21.08.2026journal-article

BMC Health Services Research

Justification of medication management resource allocation among older people living in their own homes: a qualitative study

Marianne Kollerøs Nilsen, Rose Mari Olsen, Sue Jordan, Hege Sletvold

Abstract Background In Norway, older individuals living at home who can no longer manage their own medication have the right to apply for assistance from municipal home health services. Allocation of these services is documented in individual decision letters, detailing the specific services to be provided at home. The decision should be based on each patient’s needs and the criteria for service allocation. This study explores the justification for allocating medication management resources to older people living i …

21.08.2026journal-article

Metabolites

Nicotinamide Mononucleotide Adenylyltransferase 1 and NAD+ Homeostasis in Neuroprotection and Aging

You Sun, Bowei Li, Zhengjiang Qian

Nicotinamide adenine dinucleotide (NAD+) is a fundamental metabolic cofactor and signaling molecule that supports redox reactions, DNA repair, chromatin regulation, stress adaptation, inflammation, and neuronal maintenance. Age-associated NAD+ decline has been implicated in brain aging and neurodegenerative disorders, but the causal node and limiting compartment differ across tissues and disease states. Nicotinamide mononucleotide adenylyltransferase 1 (NMNAT-1) catalyzes the final step in NAD+ biosynthesis and rep …

21.08.2026journal-article

Medicina

Clinicopathological Predictors of Pathological Response and Survival in Older Patients Undergoing Perioperative FLOT Chemotherapy for Resectable Gastric and Gastroesophageal Junction Adenocarcinoma

Aykut Özmen, Tuba Tahtalı, Gündüz Karaoğlan, Mehmet Kutlay, Ulviye Oflas, Tanju Kapağan, Nilüfer Bulut, Gökmen Umut Erdem

Background and Objectives: Evidence regarding predictors of pathological response and long-term outcomes in older patients receiving perioperative FLOT chemotherapy for resectable gastric or gastroesophageal junction cancer remains limited. We aimed to identify factors associated with pathological response and survival in patients aged ≥65 years treated with neoadjuvant FLOT. Materials and Methods: This retrospective single-center study included 86 consecutive patients (median age, 69 years; 72.1% male) aged ≥65 ye …

21.08.2026journal-article

Obstetric Anesthesia Digest

Assessing Wireless and Wearable Sensors for Continuous Blood Pressure Measurement in Obese Pregnant People

AC Kraus, YV Sebastião, JSA Stringer, A Ivins, MV Reyes Montilla, B Cobb, CE Jensen, KA Drexler, EM Stringer

( Int J Gynaecol Obstet . 2026 Mar;172(3):1791–1793. doi: 10.1002/ijgo.70484) Obesity affects nearly 1 in 3 pregnancies and significantly elevates the risk of hypertensive disorders, which are major contributors to maternal illness and death. Accurate blood pressure (BP) monitoring is essential for managing these risks. However, traditional arm cuff methods often perform poorly in individuals with larger arm circumferences, particularly when compared with intra-arterial monitoring (A-line), which is considered the …

21.08.2026journal-article

Medical Anthropology Quarterly

All in the family: Kidney donation in aging Japan

Amy Borovoy

Abstract This article examines the ethical and cultural logics shaping living donor kidney transplantation in Japan, where donation is restricted to kin and deceased donation remains rare. Drawing on ethnographic fieldwork in a Tokyo‐area hospital, it analyzes how Japan's kin‐based transplantation regime contrasts with the utilitarian model dominant in the United States, where donor pools are expanded through non‐kin and anonymous exchange. I argue that Japan's restriction to family donors reflects an ethic of care …

21.08.2026journal-article

Journal of Organizational Effectiveness: People and Performance

Sustaining employee well-being in remote work: a sustainable human resource management perspective

Britta Helga Philp, Andrew Bratton, Jennifer Jamieson O'Neil

Purpose This study explores the influence of perceived losses and gains associated with remote working on employee well-being and examines the implications for sustainable human resource management (HRM) and organisational practice. Design/methodology/approach Using semi-structured interviews with 27 UK-based counsellors, we explore the lived experiences of employees who transitioned from face-to-face to remote work and uncover the losses and gains experienced in this transition that shape employee well-being. Find …

21.08.2026journal-article

Journal of Critical Care Research and Emergency Medicine

The Importance of a Multidisciplinary Approach and Treatment of Recurrent Supraventricular Tachycardia in the Geriatric Population – A Case Report

Jakov Jurić MD

Supraventricular tachycardia (SVT) is a cardiac rhythm disorder characterized by sudden episodes of rapid heart rate and may cause palpitations, chest discomfort, and dyspnea. This case report describes a 75-year-old patient with recurrent SVT, baseline respiratory difficulties, previous right upper lobectomy, and current left-lung adenocarcinoma. During an episode of palpitations and worsening dyspnea, non-pharmacological maneuvers were unsuccessful, while intravenous administration of 6 mg adenosine resulted in r …

21.08.2026journal-article

Innovation in Aging

Reducing oral frailty improves functional independence in older Brazilians: A causal inference study of disability-free survival using longitudinal modified treatment policies

John Rong Hao Tay, Huihua Li, Karen G Peres, Rahul Malhotra, Anna Quialheiro, Eleonora D'Orsi, Marco A Peres

Abstract Background and Objectives Poor oral health is associated with functional decline and mortality in older adults, yet causal evidence linking oral health improvement with functional independence remains limited. We simulated the effects of hypothetical reductions in oral frailty on the cumulative probability of being alive and independent in basic activities of daily living (ADLs) among older adults in Brazil. Research Design and Methods Data from the EpiFloripa Aging Cohort Study of community-dwelling adult …

21.08.2026journal-article

Journal of Huntington's Disease

Indicators of need and timing of percutaneous endoscopic gastrostomy (PEG) in people with Huntington's disease: A medical chart review study

Malin Sixt Börjesson, Mathias Hall, Elisabeth Winnberg

Background In the International guidelines for nutrition in Huntington's disease (HD) PEG-tubes may be considered in persons with HD (pwHD) with severe swallowing difficulties, but there are no general recommendations for when to initiate PEG-tube placement. Little is known about factors that have led to PEG-tube placements in pwHD. Objective To study the indications and timing of the PEG-tube placement in pwHD through medical chart review. Further aims were to investigate symptoms related to dysphagia, and documen …

21.08.2026journal-article

Journal of Medical Internet Research

Can Intelligent Monitoring Help Older Adults Live Safely at Home Longer?

Jenna Congdon

Abstract With the population aged 65 years and over projected to represent 1 in 6 people by 2050, expanding health care systems’ capacity to support healthy aging in place is a growing global priority. In this News and Perspectives article, JMIR Correspondent Jenna Congdon reports on an AI-enabled system in Canada with the potential to extend health care capacity by supporting older adults to age safely and independently in place.

21.08.2026journal-article

Journal of Enterprising Communities: People and Places in the Global Economy

Widening horizons: digital technologies and social capital for female migrant entrepreneurs

Lin Xiong, Imaobong James, James Cunningham, Jialin Hardwick

Purpose This study aims to provide a deeper understanding of how digital technologies enable self-employed African female migrants in the United Kingdom to operate in the face of socially constructed disadvantages. Female migrant entrepreneurs are often characterised by their ethnicity and gendered expectations, which can ultimately constrain the nature of their business offering. In this paper, the authors look to how female migrant entrepreneurs use digital technologies as a way of overcoming social disadvantages …

21.08.2026journal-article

Perspectives on Sexual and Reproductive Health

Understanding the Reproductive Life Planning Experiences of People With Disabilities in Ontario, Canada: A Qualitative Exploration

Momina Khan, Hilary K. Brown, Yona Lunsky, Lesley A. Tarasoff

ABSTRACT Introduction Reproductive life planning can be a valuable component of reproductive health promotion. However, little is known about attitudes, desires, and intentions regarding pregnancy among people with disabilities. This exploratory qualitative study aimed to understand the reproductive life planning experiences of women and gender‐diverse people with physical, intellectual, and developmental disabilities. Methods We used purposeful sampling to recruit 29 reproductive‐aged individuals with physical, in …

21.08.2026journal-article

Medicine

A cross-sectional latent class analysis of depressive and anxiety symptoms in people aged 65 and older

Jing Zhang, Feng Li, YunTong Yao, YuQing Huang, YiXia Zhang, YangWen Yu, Xu Luo

As the older population grows, depression and anxiety have become common mental health problems that significantly undermine the quality of life of older persons. Improving older people’s mental health is vital for their quality of life. Before developing targeted interventions, priority must be given to identifying key factors affecting mental health to address the significant individual differences within this population. The aim was to identify subgroups of depressive/anxiety symptoms in the older population and …

21.08.2026journal-article

Frontiers in Aging

Sexual health needs and challenges among ageing women in Sub-Saharan Africa: a systematic review

Redson Mwandama, Yankho Henry Mdoka, Oudry Mulinde, Margubur Rahaman

Background The global ageing population is growing rapidly, with Sub-Saharan Africa undergoing a significant demographic transition. Although research on general ageing-related health outcomes in the region, such as frailty, multimorbidity, and socioeconomic deprivation, has expanded in recent years, the sexual health needs of ageing women remain comparatively understudied and inadequately addressed. This systematic review synthesizes evidence regarding the sexual health needs, challenges, and reproductive health c …

21.08.2026journal-article

Journal of Investigative Medicine

EXPRESS: Prognostic Accuracy of SPEED, NEWS, and NEWS-L for Predicting 28-Day Mortality in Geriatric Sepsis: A Prospective Study

Orhan İnaltekin, Serdar Özdemir

Background: Sepsis remains a leading cause of morbidity and mortality in older adults, and early risk stratification in the emergency department (ED) is essential for optimizing patient management. This study compared the prognostic performance of the Sequential Organ Failure Assessment (SOFA), National Early Warning Score (NEWS), National Early Warning Score–Lactate (NEWS-L), and Sepsis Prediction and Evaluation in the Emergency Department (SPEED) score for predicting 28-day mortality in geriatric patients with se …

21.08.2026journal-article

Journal of the Canadian Dental Association

Emerging findings from an interactive workshop on integrated oral health care for older adults

Mario Brondani, Paul Allison, Renata Ferretti-Rebustini, Sanam Kafili, Arya Noeerazlighi, Sadikchya Pokhrel, Swathi Ramachandran, Ann-Marie Schreiber, Michael MacEntee

This article reports on the outcomes of an interdisciplinary full-day workshop focused on interprofessional collaboration on providing oral health care for elderly people. The workshop brought together global experts, researchers, and the public to discuss the concept of interprofessional collaboration in oral health care delivery for older populations. The discussions highlighted 6 areas that formed a policy framework for action and included oral health screening integration into primary care, system requirements …

21.08.2026journal-article

Frontiers in Cardiovascular Medicine

The impact of lipoprotein(a) determination in cardiovascular risk stratification among people living with HIV

Carmen Ramos Alejos-Pita, Diego José Rodríguez Torres, Tatiana Mata Forte, Beatriz Tendero de la Asunción, Joaquín Enrique Gómez Sanz, Juan José Reyes Luján, Matteo Romano, Edurne López Soberón, Francisco Javier Membrillo de Novales, Miriam Estébanez Muñoz

Objectives Human immunodeficiency virus (HIV) infection has become a chronic condition due to antiretroviral therapy (ART), which has increased life expectancy but is also associated with a higher burden of cardiovascular disease (CVD) in people living with HIV (PLHIV). Lipoprotein(a) [Lp(a)] is an independent cardiovascular risk biomarker; however, its role in PLHIV remains unclear. This study evaluated the relationship between Lp(a) and cardiovascular risk and explored its association with subclinical coronary ar …

21.08.2026journal-article

Trayectorias Humanas Trascontinentales

Décoloniser la santé des femmes âgées : savoirs profanes, injustice épistémique et droit à la protection de la santé en France

Ambre LAPLAUD

Les femmes âgées constituent un angle mort structurant des politiques de santé publique françaises: plus longévives, plus pauvres et plus isolées, elles cumulent des désavantages que ni la sociologie de la santé ni le droit à la protection de la santé n'ont pleinement appréhendés dans une perspective intersectionnelle. Cet article propose une analyse transdisciplinaire organisée autour de trois registres. Premièrement, la décolonisation de la santé publique et la notion d'épistémicide - destruction systémique de sa …

21.08.2026journal-article

BMC Public Health

Using the behaviour change wheel to co-design an intervention to interrupt prolonged bouts of sedentary behaviour in older homeworking employees

Lily Mott, Amelia Parchment, Annemarie Money, Sheena Johnson, Chris Todd, Danielle Harris

Abstract Background Sedentary desk-based workers are at risk of adverse health. With hybrid working on the rise, interventions suitable for homeworkers are needed. Given the ageing working population, it is imperative to ensure older employees (≥ 50) can remain economically active in the years before retirement, without being exposed to additional health risks. This study aimed to use co-design methods, guided by the Behaviour Change Wheel (BCW), to develop an intervention to help interrupt prolonged bouts of seden …

21.08.2026journal-article

Annual Review of Nutrition

Mechanisms of NAD+ Homeostasis in Aging and Disease

Melanie R. McReynolds

Aging is the greatest risk factor for many of society's most prevalent diseases, including diabetes, cancer, cardiovascular disease, and neurodegenerative disorders. A common thread underlying these conditions is the disruption of cellular and metabolic homeostasis. All hallmarks of aging converge on mechanisms that disrupt how cells communicate, interact, and coordinate their functions. Emerging studies have implicated diminished NAD + levels as a contributor to several hallmarks of aging, underscoring their regul …

21.08.2026journal-article

Medical Sciences

Orthopaedic Trauma in Patients with Documented Alcohol Use: Injury Mechanisms, Clinical Characteristics, and Geriatric Vulnerability

Irina Sirbu, Bianca-Ana Dmour, Stefan-Dragos Tîrnovanu, Bogdan Puha, Eliza-Geanina Cogian, Mariana Zubenschi, Alexandru Filip, Ioana-Dana Alexa, Mihaela-Camelia Tîrnovanu, Popescu Dragos-Cristian, Adrian-Claudiu Carp, Awad Dmour

Background: Alcohol-related conditions may influence both injury patterns and in-hospital management in orthopaedic trauma. This study evaluated the clinical characteristics, injury mechanisms, treatment patterns, and hospital outcomes of adults with acute orthopaedic trauma and documented alcohol use, with particular attention to geriatric vulnerability and alcohol withdrawal. Methods: This retrospective single-centre cohort included adults admitted between January 2018 and December 2025 with acute musculoskeletal …

21.08.2026journal-article

Journal of Intelligent Decision Making and Information Science

AI-Enabled IoT Wearable System for Real-Time Fall Detection and Emergency Alerting in Older Adults

Chandrani Mukherjee

Falls are a significant health issue for older people, and can result in injury, disability, hospitalisation and loss of independence. Continuous monitoring and quick caregiver notification can be enabled using an AI-powered wearable IoT system. Objective: The purpose of this study was to design and test an edge-based wearable IoT framework for real-time fall detection based on the accelerometer and gyroscope signals. Methodology: A synthetic dataset was created by using the features of SisFall and MobiAct, includi …