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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Journal of Primary Care Dentistry and Oral Health

Chairside Direct Fabrication of Cheek Plumpers on an Existing Complete Denture for Facial Esthetic Rehabilitation: A Clinical Case Report

Guddolla Venkata Prasanna, Karukayil Amrutha Mohanbabu, Vinnakota Dileep Nag

Abstract Esthetic rehabilitation in completely edentulous patients involves restoration of function and facial appearance. Loss of buccal fat, muscular tone, and alveolar bone support may result in sunken cheeks and compromised facial esthetics. Cheek plumpers support the facial musculature but are commonly incorporated during fabrication of new dentures; however, some patients may be unwilling to replace well-fitting existing prostheses. This clinical case report describes the conservative management of a patient …

28.08.2026journal-article

International Journal of Environmental Research and Public Health

Impact of Aerobic Training on Cardiometabolic Markers and Menopausal Symptoms: A Stratified Analysis by Multimorbidity

Juliene G. Costa, Igor M. Mariano, Ana Clara R. Cunha, Juliana C. Silva, Ludimila F. Gonçalves, Mateus L. Rodrigues, Julia B. Tavares, Victor Hugo V. Carrijo, Ana Luiza Amaral, Guilherme M. Puga

Cardiometabolic multimorbidity is highly prevalent among postmenopausal women and is associated with adverse metabolic outcomes and a greater burden of climacteric symptoms. This secondary analysis of a quasi-experimental controlled clinical trial investigated the effects of a 12-week aerobic training program on climacteric symptoms, menopause-related quality of life, body composition, and cardiometabolic biomarkers in postmenopausal women with and without cardiometabolic multimorbidity. Forty-one postmenopausal wo …

28.08.2026journal-article

Health Promotion Practice

Effectiveness of Social Cognitive Theory–Based Oral Cancer Awareness Module Among Adolescents: An Interventional Study

Tejaswini B. Darukaradhya, Shwetha Kanyaloor Mallikarjuna, Pushpanjali Krishnappa, Anju James

Oral cancer remains a significant public health challenge, particularly in India, where it accounts for a substantial global burden. Despite its preventability, awareness levels among adolescents remain low. Schools provide an ideal platform for health education interventions, yet traditional approaches often fail to yield lasting behavioural change. This study aimed to evaluate the effectiveness of a social cognitive theory (SCT)-based oral cancer awareness module in enhancing adolescents’ knowledge and self-effic …

28.08.2026journal-article

Child and Adolescent Psychiatry and Mental Health

Children referred as victims and alleged offenders for forensic psychiatric evaluation: distinct psychiatric profiles and machine-learning–based classification of post-traumatic stress disorder in a Turkish sample

Yasemin İmrek, Gökçe Koçak Çetin, Büşra Nur Kansu, Mesut Sari, Oya Kalaycioğlu, Ali Evren Tufan

Abstract Background Children referred for forensic psychiatric evaluation represent a heterogeneous and vulnerable population comprising both victims and alleged offenders, who may differ substantially in their psychopathological and cognitive characteristics. Evidence from non-Western legal and cultural contexts remains limited, and few studies have applied complementary classical and machine-learning approaches to identify factors associated with post-traumatic stress disorder (PTSD) in this group. This study aim …

28.08.2026journal-article

Journal of Hospital Administration

Do state-level cultural competency educational mandates influence patient experience?

Mohammed Alzeen, Devdutt Upadhye, Rita DiLeo, Philip Cendoma, Kristine Hearld, Nancy Borkowski

Objective: We examined whether state cultural competency educational mandates are associated with patient-reported Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) scores. Methods: Analyzing data from 2018 and 2023 HCAHPS surveys, we compared state-level scores from 48 states and the District of Columbia (DC). Five states with cultural competency mandates (California, Connecticut, New Jersey, Oregon, Washington) were compared against five matched states and 38 remaining states with DC. Resu …

28.08.2026journal-article

Frontiers in Public Health

Associations between various obesity-related indicators and hypertension: a national cross-sectional survey with 117,609 Chinese adults

Chenglong Wang, Yini Wu, Mingjian Nie, Duobujie, Chenhui Xiao, Wanglong He, Chaoqun Fan, Qiang Feng, Jingjing Wang

Objective To evaluate how well obesity-related indicators (ORIs) discriminate hypertension in Chinese adults, thereby identifying the best-performing metrics and clarifying their dose–response associations with hypertension. Methods This study analyzed data from the 2020 National Physical Fitness Surveillance Database, comprising 117,609 adults aged 20–79 years with complete data on 10 ORIs and relevant covariates. Receiver Operating Characteristic (ROC) curves were employed to evaluate the discriminatory ability o …

28.08.2026journal-article

Journal of Clinical Immunology

Preferential Retention of the LMP-1 Promoter at EBV Integration Sites in Lymphomas: Evidence from Cartilage Hair Hypoplasia and Controls

Zachery W. Dickson, Lari Pyöriä, Annika Kangas, Eetu Pello, Leo Hannolainen, Aino Mutka, Hanna-Leena Kukkola, Pasi Huttunen, Yossra H. S. Zidi-Mouaffak, Klaus Hedman, Mervi Taskinen, Panu E. Kovanen, Svetlana Vakkilainen, Maria F. Perdomo, Outi Mäkitie

Abstract Purpose Cartilage-Hair Hypoplasia (CHH), a rare ribosomopathy characterized by immune deficiency, carries a markedly increased risk of early-onset malignancy, particularly lymphoma. However, the molecular drivers of malignant transformation in CHH, and the contribution of viruses to this process, remain poorly defined. Methods We performed targeted virome sequencing of 41 DNA viruses on FFPE tumor samples (primarily lymphomas) from 15 CHH patients and three malignancy-matched controls per patient. Subseque …

28.08.2026journal-article

Molecular Medicine

Deletion of protein tyrosine phosphatase 1B in hepatocytes attenuates inflammation, steatosis, and fibrosis in a dietary mouse model of metabolic dysfunction-associated steatohepatitis

Ming-Fo Hsu, Yoshihiro Ito, Ulrik Mjaaseth, James Graham, Peter J. Havel, Fawaz G. Haj

Abstract Background Metabolic dysfunction-associated steatohepatitis (MASH) is a leading cause of liver-related morbidity and mortality. The current interventions are limited, underscoring the need for novel mechanism-based therapies. Protein tyrosine phosphatase 1B (PTP1B) regulates phosphotyrosine signaling and hepatic metabolism, but its role in MASH remains incompletely understood. Methods To elucidate the impact of modulating PTP1B expression in MASH, we used mice with hepatocyte-specific PTP1B disruption in t …

28.08.2026journal-article

Frontiers in Public Health

Patient perspectives on pain care pathways: informing implementation with insights from trial evidence

Lindsay A. Ballengee, Susan N. Hastings, Trevor A. Lentz, Katlin Harker, Steven Z. George

Background Few studies have examined whether patients' perceptions of low back pain (LBP) care pathways are influenced by evidence of their effectiveness. To inform future implementation efforts, we conducted an exploratory qualitative study examining how individuals with low back pain interpreted two pain care pathways that emphasized non-drug treatment options: a physical therapy–focused model (Sequenced Care Pathway) and a navigator-led model (Pain Navigator Pathway). We explored how individuals with low back pa …

28.08.2026journal-article

Frontiers in Public Health

A multicenter cross-sectional study on proactive health knowledge, attitude, and practice and its influencing factors among resident standardized training physicians in Guangxi

Qian Zeng, Jichen He, Kun Ye, Xuepeng Du, Jianzhen Chang, Qiaoying Wei, Shenglin Liang

Objective The purpose of this study is to examine the state of proactive health knowledge, attitude, and practice (KAP) among Guangxi’s resident standardized training physicians as well as the factors that affect it. The results will be used to optimize health management strategies. Methods A multicenter cross-sectional survey was conducted. Univariate analysis was used to compare differences in proactive health KAP among residents with different characteristics, and multivariate linear regression was performed to …

28.08.2026journal-article

LGBT Health

Well-Being Among Sexual and Gender Minority Victims of Intimate Partner Violence: A Scoping Review

Hannah R. Seidman, Ivy K. Ho

Purpose: This review aimed to provide an overview of the well-being outcomes identified among sexual and gender minority (SGM) victims of intimate partner violence (IPV). Methods: This review followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines for scoping reviews. Results were extracted from APA PsycInfo, APA PsycArticles, CINAHL, CINAHL Plus with Full Text, and MEDLINE. Studies were included if participants were aged 18 or older, identified as a sexual and/or gender minority …

28.08.2026journal-article

Russian Journal of Clinical Dermatology and Venereology

Antibacterial resistance in dermatology: a modern perspective on the problem and the place of amoxicillin/clavulanic acid in the treatment of bacterial skin infections

E.V. Svechnikova, S.E. Zhufina

Introduction. The problem of microbial resistance to antibacterial drugs is becoming increasingly pressing each year and poses a global threat to public health. In dermatological practice, systemic antibiotics are widely used for both skin and soft tissue infections and chronic inflammatory dermatoses (acne, rosacea, hidradenitis suppurativa), which increases the risk of resistant strain selection and microbiome disruption. Objective. To analyze current literature data and our own clinical observations, as well as …

28.08.2026journal-article

Russian Journal of Clinical Dermatology and Venereology

Correction of facial skin aging signs using exosomes

T.N. Korolkova, I.A. Shepilova, T.G. Dovbeshko

Background. Skin aging is a multifactorial process caused by internal mechanisms and external influences. Gradual changes in the epidermis and dermis lead to impaired skin functions. Restoring these functions is an important task. Objective. Evaluation of the results of using a two-component complex with exosomes in patients with signs of facial skin aging. Material and methods. During this study, 22 patients (mean age 53.1±1.3 years) with Fitzpatrick skin phototypes I-III, wrinkles and other signs of facial aging …

28.08.2026journal-article

REST Journal on Data Analytics and Artificial Intelligence

A Multi-Criteria Assessment of Gastrointestinal Nursing Specialties: Insights from the MOORA Approach

Srividya Velmurugan

The quality of gastrointestinal nursing services plays an important role in improving patient outcomes and satisfaction. This study assessed five specialties—Digestive Health Nursing, GI Endoscopy Nursing, Colorectal Nursing, Hepatology Nursing, and Abdominal Nursing—using four major criteria: patient assessment and monitoring, care planning and implementation, patient education and support, and professional collaboration. The MOORA(Multi-Objective Optimization on the basis of Ratio Analysis) method was applied to …

28.08.2026journal-article

Statistics in Medicine

Penalized Cumulative Probability Model for a Continuous Outcome Subject to Detection Limits

Shuai Sun, Valeria R. Mas, Kellie J. Archer

ABSTRACT Mixed‐type outcome data occur when the outcome variable's distribution is a mixture of both continuous and discrete ordinal variables. Such mixed‐type outcomes are common in biomedical, psychological, and the health sciences, particularly for variables having either a detection or quantitation limit. When interest lies in identifying a combination of genomic features associated with a mixed‐type outcome, any method used would require a variable selection strategy for high‐dimensional data. Unfortunately, f …

28.08.2026journal-article

Medicine

Genetically proxied circulating PD-1/PD-L1 levels and broadly defined myocarditis

Fengyi Liu, Qian Yang

Myocarditis is an inflammatory myocardial disease with potentially severe outcomes. Programmed cell death protein 1 (PD-1) and programmed death-ligand 1 (PD-L1) regulate immune tolerance, but the association between lifelong genetically proxied circulating PD-1/PD-L1 levels and broadly defined myocarditis remains uncertain. We investigated these associations and explored related plasma lipid species. We conducted bidirectional 2-sample Mendelian randomization using proteomic genome-wide association data from the UK …

28.08.2026journal-article

Medicine

Impact of an educational intervention on rational laboratory test ordering and healthcare costs in family medicine

Muhammet Şahinol, Hüseyin Nejat Küçükdağ

This study aims to analyze the impact of “Rational Laboratory Test Ordering” training given to family medicine residents on their test request habits, number of tests, and costs. A total of 27,085 applications made to the Family Medicine Polyclinic of Düzce University Faculty of Medicine between June 1, 2022, and June 1, 2024, were retrospectively examined. Based on the educational intervention provided to resident doctors on June 1, 2023, the periods before and after were compared in terms of the total number of t …

28.08.2026journal-article

Medicine

Temporal maintenance of an adolescent suicide attempt screening score in national surveys

Xiaotian Ma, Su Jia, Junjie Zhang

Screening scores may retain risk ranking while their probabilities become inaccurate in later populations. The information needed to repair this temporal drift is rarely quantified for adolescent suicide screening. We analyzed 5 independent national Youth Risk Behavior Survey cross sections from 2015 through 2023. Of 81,401 sampled students, 68,682 had observed past year attempt status. A survey weighted 2015 ridge score based on 14 harmonized predictors was frozen and transported to 4 later surveys. For each later …

28.08.2026journal-article

Critical Care & Emergency Medicine

Radiofrecuencia convencional y pulsada armonizada en el ganglio de Gasser para el tratamiento de la neuralgia del trigémino: resultados del protocolo Dolomedic

Francisco Javier Machuca Vigil, Rafael Orlando Vallejo Estrella, Roberto Jameson Rosales, Francesca Dolciami, Eduardo Perez Lozano

Objectives: To describe the experience with the Dolomedic protocol, which combines conventional radiofrequency (CRF) and harmonized pulsed radiofrequency (PRF) of the Gasserian ganglion, for the treatment of refractory trigeminal neuralgia. Material and Methods: A retrospective study was conducted in 77 patients with unilateral type 1 and 2 trigeminal neuralgia treated between July 2020 and July 2025 at Dolomedic Alta Especialidad (Heroica Matamoros, Mexico). The percutaneous approach to the Gasserian ganglion was …

28.08.2026journal-article

Critical Care & Emergency Medicine

Reanimación con líquidos guiada por metas en choque séptico: estado actual y controversias

Diego Escarraman Martinez

La administración de fluidos intravenosos constituye la piedra angular en la reanimación inicial del choque séptico; sin embargo, el exceso de líquidos se ha asociado directamente con peor pronóstico, edema tisular y mayor mortalidad. La presente revisión analiza el paso de una reanimación liberal a estrategias restrictivas y guiadas por parámetros dinámicos de respuesta a volumen en pacientes críticos.

28.08.2026journal-article

The Open Nursing Journal

Effectiveness of the Basic Infection Control Skills License (BICSL) Training Program on Nurses' Knowledge, Attitudes, and Practices in Makkah, Saudi Arabia

Azizah Banafi, Noor Mastura Mohd Mujar

Introduction Healthcare-associated infections (HCAIs) remain a major global health concern. In Saudi Arabia, the Basic Infection Control Skills License (BICSL) program was introduced to standardize infection prevention and control (IPC) training among healthcare workers. However, evidence on its effectiveness among nurses remains limited. Methods A multicenter, quasi-experimental, one-group pre-post study was conducted among 360 nurses from 5 public hospitals in Makkah, Saudi Arabia, during the 2024 BICSL implement …

28.08.2026journal-article

Polymers for Advanced Technologies

Advancements in Sodium Alginate‐Based Colloidal Drug Delivery Systems: Bridging Research Into Clinical Practice

Ashutosh Gupta, Aniket Navale, Debadrita Ghosh, Parekh Nirmit Jigneshkumar, Kuljeet Kaur, Aditya Dev Rajora, Soji Soman, Sally A. EL‐Zahaby

ABSTRACT Sodium alginate, an anionic polysaccharide obtained from brown algae and a versatile biomaterial for colloidal drug delivery systems. It has good biocompatibility, biodegradability, and mucoadhesive nature. Alginate has controlled and targeted drug delivery applications. This review discusses sodium alginate–based colloidal systems and presents fundamental research with potential for clinical translation. Alginate can undergo ionic crosslinking with divalent cations such as calcium with a wide range of del …

28.08.2026journal-article

Journal of Clinical Medicine

Diagnostic and Clinical Patterns of Newly Diagnosed ANCA-Associated Vasculitis Before and After the 6 February 2023 Kahramanmaraş Earthquakes: A Multicenter Retrospective Study from Affected Provinces

Sezgin Zontul, Gezmiş Kimyon, Fuat Albayram, Anıl Göçer, Rabia Sağır, Aylin Dolu Karaca, Elif İnanç, Zeynep Kaya, Mesude Seda Aydoğdu, İpek Balıkçı Çiçek, Gözde Yıldırım Çetin, Servet Yolbaş

Background/Objectives: The relationship between large-scale natural disasters and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) remains uncertain. This study compared crude case numbers, diagnostic patterns, and clinical characteristics of newly diagnosed AAV before and after the 6 February 2023 Kahramanmaraş earthquakes in Türkiye. Methods: This multicenter retrospective study included patients newly diagnosed with AAV between 6 February 2020 and 5 February 2026 at five tertiary referral c …

28.08.2026journal-article

Europe’s Journal of Psychology

Effectiveness of cognitive behavioural therapy on sleep outcome for patients with chronic fatigue syndrome in a routine clinical service

Chotiman Chinvararak, Olivia Sterry, Trudie Chalder

Objective We aimed to study the effectiveness of CBT for sleep difficulties in patients with chronic fatigue syndrome/myalgic encephalitis (CFS/ME). Method We conducted a retrospective cohort study at the Persistent Physical Symptoms Research and Treatment Unit, Maudsley Hospital, between 2014 and 2019. The primary outcome was sleep quality and other sleep parameters assessed by the Pittsburgh Sleep Quality Index (PSQI). The secondary assessments comprised the Chalder Fatigue Questionnaire (CFS), the Work and Socia …