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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

IIARD International Journal of Banking and Finance Research

Public Debt Financing Strategies and Their Impact on Sustainable Economic Growth in Nigeria

Ogechukwuka CHEGWE

This study examines the impact of public debt financing strategies on sustainable economic growth in Nigeria between 1990 and 2024. The research employs secondary time-series data obtained from the World Bank, Debt Management Office, and Central Bank of Nigeria, analyzing the relationships between public debt indicators and economic performance. Using an econometric regression model, the study investigates how debt-to-GDP ratio, interest paymentsto-revenue, gross fixed capital formation, inflation, real interest ra …

28.08.2026journal-article

The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences

Biological Age Associates with Longitudinal Frailty-Related Functional Decline: The Health and Retirement Study

Savvina Prapiadou, Tamara N Kimball, Benjamin Y Q Tan, Reinier W P Tack, Devanshi Choksi, Marie-Gabrielle Duperron, Jasper R Senff, Evy M Reinders, Tan Li Feng, Sanjula D Singh, Jonathan Rosand, Christopher D Anderson

Abstract Epigenetic clocks have emerged as markers of biological aging. Understanding their association with age-related functional decline may provide insights into DNA-mediated mechanisms underlying frailty-related functional decline and reveal which clocks best associate with accelerated functional decline. We therefore examined associations between established epigenetic clock measures and longitudinal trajectories of cognitive function, grip strength, and walking speed. We analyzed data from 4,018 participants …

28.08.2026journal-article

Asclepius International Journal of Scientific Health Science

IMPACTOS DA VIOLÊNCIA SEXUAL NA SAÚDE BUCAL E SUA RELAÇÃO COM A CARCINOGÊNESE ORAL EM ODONTOLOGIA E CIRURGIA DE CABEÇA E PESCOÇO

Wilson Pereira de Queiroz, Pedro Fechine Honorato, Natalia da Costa Maciel, Carla Gabriella Carvalho de Sousa Barbosa, Noelia Claudino Solidade Da Cunha, Patriciah Dal Moro, Rodrigo Teixeira Santiago, Gabriel Garcia da Silva, Arthur Inacio do Prado, Israel Santos de Macêdo

Objetivo: Sintetizar as evidências científicas sobre a atuação conjunta entre a cirurgia de cabeça e pescoço (CCP) e a odontologia no diagnóstico precoce, na prevenção de traumatismos orofaciais e no manejo de complicações decorrentes da terapia oncofacial. Metodologia: Revisão integrativa da literatura realizada nas bases PubMed, Scopus, Web of Science, SciELO, LILACS e no acervo da Seven Editora, englobando publicações entre 2022 e 2026. A amostragem final foi composta por trinta e seis estudos selecionados após …

28.08.2026journal-article

Journal of Mechanics in Medicine and Biology

BIOMECHANICAL ANALYSIS OF MICROCALCIFICATION EFFECTS ON INTRACRANIAL ANEURYSM RUPTURE

RONG-YE ZHENG, CHENG-TAO ZHU, CHEN ZHANG, WEN-YAO HONG

With the development of vascular imaging technology, microcalcifications have been popularly identified in patients with intracranial aneurysm. However, the potential association between microcalcifications and aneurysm rupture remains unclear. In this study, three patient-specific aneurysm cases were combined with simplified calcification models, and finite element analysis was performed to investigate the effect of microcalcification on mechanical properties. The equivalent stress distributions were obtained sepa …

28.08.2026journal-article

Journal of Mechanics in Medicine and Biology

ADAPTIVE IMPEDANCE CONTROL OF LOWER LIMB REHABILITATION ROBOT OPTIMIZED BY THE SPARROW SEARCH ALGORITHM FOR SPORTS FRACTURE REHABILITATION

HANG YIN, XI LING

Traditional lower limb rehabilitation robots suffer from low motion intention recognition accuracy and poor human-robot compliance, which may cause secondary injury to athletes with lower limb fractures. To solve this problem, this study proposes a hybrid control system combining the sparrow search algorithm optimized back propagation neural network (SSA-BP) and adaptive impedance control (AIC). The SSA-BP model is adopted to extract features from surface electromyography (sEMG) signals and recognize human motion i …

28.08.2026journal-article

Izmir Katip Celebi University Faculty of Medicine

ANALYSIS OF TRIAGE CODE AND DIAGNOSIS DISTRIBUTIONS OF PATIENTS ARRIVING VIA 112 EMERGENCY SERVICES

Emre Kahveci, Zehra Aldemir, Mazlum Aslan, Berivan Ağaoğlu, Ejder Saylav Bora

ABSTRACT Objective: The aim of this study is to interpret the use of 112 emergency medical services by revealing the demographic characteristics, triage code and diagnosis distributions, and outcomes of patients who arrived at a training and research hospital via 112. Method: This study retrospectively examined patients who arrived at the emergency department of İKÇÜ Atatürk Training and Research Hospital by ambulance between January 1 and December 31, 2024, using the hospital information system. Patients with inco …

28.08.2026journal-article

International Journal of Health Management Review

COLORECTAL CANCER SCREENING STATUS AND ASSOCIATED FACTORS AMONG ADULTS IN CAN THO CITY, VIETNAM

Nguyen Huu Ky Phuong

Objective: To describe colorectal cancer (CRC) screening status and identify associated factors among adults aged 45-74 years in Can Tho City, Vietnam. Methods: This analytical cross-sectional study included 600 participants from 12 clusters. Frequencies, proportions, and adjusted odds ratios (aORs) were estimated using multivariable logistic regression with cluster-adjusted standard errors. Results: Overall, 159 participants (26.5%) were up to date with CRC screening. Among those screened, 59.1% had undergone colo …

28.08.2026journal-article

Journal of Science, Technology and Innovation Research

Development of an Explainable Machine Learning Model For Hypertention Risk Prediction Using Basic Clinical Parameters

Olutola Agbelusi

Hypertension is one of the major contributors for gravid women and unborn child’ death especially in the developing countries where access to innovative diagnostic technologies is not common. The study used explainable machine learning algorithm to predict hypertension risk using basic clinical attributes. Pregnant women record in the Mother and Child Hospital in Akure was collected and preprocessed to address missing values, regulate the features, and enhance overall data quality. The data partitioning at 80% for …

28.08.2026journal-article

Frontiers in Computing and Intelligent Systems

Optimization of Deep Integration of Data Analysis and Intelligent Scheduling for University Public Resource Allocation Systems

Yaoen Xu

This paper studies the deep integration and optimization of data analysis and intelligent scheduling for university public resource allocation systems. To address the issues of inaccurate prediction, single algorithm, and disconnection between data and scheduling in traditional rule-driven systems, a data-driven intelligent decision scheme is proposed. The LSTM prediction model is optimized by integrating university-specific contextual features, and a PPO-based deep reinforcement learning algorithm is employed for …

28.08.2026journal-article

Critical Care & Emergency Medicine

Reanimación con líquidos guiada por metas en choque séptico: estado actual y controversias

Diego Escarraman Martinez

La administración de fluidos intravenosos constituye la piedra angular en la reanimación inicial del choque séptico; sin embargo, el exceso de líquidos se ha asociado directamente con peor pronóstico, edema tisular y mayor mortalidad. La presente revisión analiza el paso de una reanimación liberal a estrategias restrictivas y guiadas por parámetros dinámicos de respuesta a volumen en pacientes críticos.

28.08.2026journal-article

Critical Care & Emergency Medicine

Radiofrecuencia convencional y pulsada armonizada en el ganglio de Gasser para el tratamiento de la neuralgia del trigémino: resultados del protocolo Dolomedic

Francisco Javier Machuca Vigil, Rafael Orlando Vallejo Estrella, Roberto Jameson Rosales, Francesca Dolciami, Eduardo Perez Lozano

Objectives: To describe the experience with the Dolomedic protocol, which combines conventional radiofrequency (CRF) and harmonized pulsed radiofrequency (PRF) of the Gasserian ganglion, for the treatment of refractory trigeminal neuralgia. Material and Methods: A retrospective study was conducted in 77 patients with unilateral type 1 and 2 trigeminal neuralgia treated between July 2020 and July 2025 at Dolomedic Alta Especialidad (Heroica Matamoros, Mexico). The percutaneous approach to the Gasserian ganglion was …

28.08.2026journal-article

Medicine

Genetically proxied circulating PD-1/PD-L1 levels and broadly defined myocarditis

Fengyi Liu, Qian Yang

Myocarditis is an inflammatory myocardial disease with potentially severe outcomes. Programmed cell death protein 1 (PD-1) and programmed death-ligand 1 (PD-L1) regulate immune tolerance, but the association between lifelong genetically proxied circulating PD-1/PD-L1 levels and broadly defined myocarditis remains uncertain. We investigated these associations and explored related plasma lipid species. We conducted bidirectional 2-sample Mendelian randomization using proteomic genome-wide association data from the UK …

28.08.2026journal-article

Medicine

Impact of an educational intervention on rational laboratory test ordering and healthcare costs in family medicine

Muhammet Şahinol, Hüseyin Nejat Küçükdağ

This study aims to analyze the impact of “Rational Laboratory Test Ordering” training given to family medicine residents on their test request habits, number of tests, and costs. A total of 27,085 applications made to the Family Medicine Polyclinic of Düzce University Faculty of Medicine between June 1, 2022, and June 1, 2024, were retrospectively examined. Based on the educational intervention provided to resident doctors on June 1, 2023, the periods before and after were compared in terms of the total number of t …

28.08.2026journal-article

Medicine

Temporal maintenance of an adolescent suicide attempt screening score in national surveys

Xiaotian Ma, Su Jia, Junjie Zhang

Screening scores may retain risk ranking while their probabilities become inaccurate in later populations. The information needed to repair this temporal drift is rarely quantified for adolescent suicide screening. We analyzed 5 independent national Youth Risk Behavior Survey cross sections from 2015 through 2023. Of 81,401 sampled students, 68,682 had observed past year attempt status. A survey weighted 2015 ridge score based on 14 harmonized predictors was frozen and transported to 4 later surveys. For each later …

28.08.2026journal-article

Acta Paediatrica

Trends in Childhood Underweight in Norwegian Children: Data From Routine Child Healthcare, 2010–2022

Sara‐Rebekka Færø Linde, Roy Miodini Nilsen, Mathieu Roelants, Melissa R. Balthasar, Jennifer L. Baker, Dorthe C. Pedersen, Boye Welde, Marjolein M. Iversen, Petur B. Juliusson, Anne‐Siri Fismen

ABSTRACT Aim This study examined age‐ and sex‐specific prevalence and trends in underweight among Norwegian children and adolescents during the pre‐pandemic period from 2010 to 2019 and COVID‐19 pandemic period from 2020 to 2022. Methods Height and weight data from 78 024 children aged 2 to 13 years in Bergen from 2010 to 2022 were obtained from public health clinic and school health service records. Underweight grades 1 to 3 were defined using the International Obesity Task Force cut‐offs. Age‐ and sex‐specific pr …

28.08.2026journal-article

Trials

Efficacy and safety of SP16 in preventing acute kidney injury in at-risk subjects with chronic kidney disease undergoing elective cardiac surgery using the heart–lung-machine (EASE-AKI): study protocol for a prospective, randomised, double-blind, placebo-controlled clinical trial

Tilman Jobst-Schwan, Karl Bihlmaier, Dana Austin, Cohava Gelber, Ann-Sophie Kaemmerer-Suleiman, Mathieu Suleiman, Robert Cesnjevar, Frank Harig, Mario Schiffer

Abstract Background Cardiac surgery using cardiopulmonary bypass uses controlled hypoperfusion which leads to relative organ damage. Acute kidney injury is the most frequent and most important organ failure, in particular in patients with chronic kidney disease. To date, there are no approved drug treatments that could effectively prevent acute kidney injury. SP16, an agonist of the low-density lipoprotein receptor-related protein 1, has been shown to exert both kidney- and cardioprotective effects in preclinical t …

28.08.2026journal-article

Frontiers in Public Health

A multicenter cross-sectional study on proactive health knowledge, attitude, and practice and its influencing factors among resident standardized training physicians in Guangxi

Qian Zeng, Jichen He, Kun Ye, Xuepeng Du, Jianzhen Chang, Qiaoying Wei, Shenglin Liang

Objective The purpose of this study is to examine the state of proactive health knowledge, attitude, and practice (KAP) among Guangxi’s resident standardized training physicians as well as the factors that affect it. The results will be used to optimize health management strategies. Methods A multicenter cross-sectional survey was conducted. Univariate analysis was used to compare differences in proactive health KAP among residents with different characteristics, and multivariate linear regression was performed to …

28.08.2026journal-article

Frontiers in Public Health

Patient perspectives on pain care pathways: informing implementation with insights from trial evidence

Lindsay A. Ballengee, Susan N. Hastings, Trevor A. Lentz, Katlin Harker, Steven Z. George

Background Few studies have examined whether patients' perceptions of low back pain (LBP) care pathways are influenced by evidence of their effectiveness. To inform future implementation efforts, we conducted an exploratory qualitative study examining how individuals with low back pain interpreted two pain care pathways that emphasized non-drug treatment options: a physical therapy–focused model (Sequenced Care Pathway) and a navigator-led model (Pain Navigator Pathway). We explored how individuals with low back pa …

28.08.2026journal-article

Frontiers in Endocrinology

The gamma-glutamyltransferase-to-estimated glomerular filtration rate composite index is associated with arterial stiffness: a cross-sectional secondary analysis of a health check-up population

Tengfei Gu, Guanghui Li, Gen Li, Pan Gao, Yang Su, Xiaoyang Li, Ziniu Zhao

Background Elevated gamma-glutamyltransferase (GGT), a marker of oxidative stress and cardiometabolic burden, and reduced estimated glomerular filtration rate (eGFR) are each linked to arterial stiffness, but they are usually examined separately. This study evaluated whether a single index integrating both—the GGT–eGFR composite index—is associated with brachial-ankle pulse wave velocity (baPWV). Methods This was a cross-sectional analysis of 893 adults from a Japanese health check-up program. The composite index w …

28.08.2026journal-article

Frontiers in Public Health

Associations between various obesity-related indicators and hypertension: a national cross-sectional survey with 117,609 Chinese adults

Chenglong Wang, Yini Wu, Mingjian Nie, Duobujie, Chenhui Xiao, Wanglong He, Chaoqun Fan, Qiang Feng, Jingjing Wang

Objective To evaluate how well obesity-related indicators (ORIs) discriminate hypertension in Chinese adults, thereby identifying the best-performing metrics and clarifying their dose–response associations with hypertension. Methods This study analyzed data from the 2020 National Physical Fitness Surveillance Database, comprising 117,609 adults aged 20–79 years with complete data on 10 ORIs and relevant covariates. Receiver Operating Characteristic (ROC) curves were employed to evaluate the discriminatory ability o …

28.08.2026journal-article

Molecular Medicine

Deletion of protein tyrosine phosphatase 1B in hepatocytes attenuates inflammation, steatosis, and fibrosis in a dietary mouse model of metabolic dysfunction-associated steatohepatitis

Ming-Fo Hsu, Yoshihiro Ito, Ulrik Mjaaseth, James Graham, Peter J. Havel, Fawaz G. Haj

Abstract Background Metabolic dysfunction-associated steatohepatitis (MASH) is a leading cause of liver-related morbidity and mortality. The current interventions are limited, underscoring the need for novel mechanism-based therapies. Protein tyrosine phosphatase 1B (PTP1B) regulates phosphotyrosine signaling and hepatic metabolism, but its role in MASH remains incompletely understood. Methods To elucidate the impact of modulating PTP1B expression in MASH, we used mice with hepatocyte-specific PTP1B disruption in t …

28.08.2026journal-article

Journal of Hospital Administration

Do state-level cultural competency educational mandates influence patient experience?

Mohammed Alzeen, Devdutt Upadhye, Rita DiLeo, Philip Cendoma, Kristine Hearld, Nancy Borkowski

Objective: We examined whether state cultural competency educational mandates are associated with patient-reported Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) scores. Methods: Analyzing data from 2018 and 2023 HCAHPS surveys, we compared state-level scores from 48 states and the District of Columbia (DC). Five states with cultural competency mandates (California, Connecticut, New Jersey, Oregon, Washington) were compared against five matched states and 38 remaining states with DC. Resu …

28.08.2026journal-article

Journal of Clinical Immunology

Preferential Retention of the LMP-1 Promoter at EBV Integration Sites in Lymphomas: Evidence from Cartilage Hair Hypoplasia and Controls

Zachery W. Dickson, Lari Pyöriä, Annika Kangas, Eetu Pello, Leo Hannolainen, Aino Mutka, Hanna-Leena Kukkola, Pasi Huttunen, Yossra H. S. Zidi-Mouaffak, Klaus Hedman, Mervi Taskinen, Panu E. Kovanen, Svetlana Vakkilainen, Maria F. Perdomo, Outi Mäkitie

Abstract Purpose Cartilage-Hair Hypoplasia (CHH), a rare ribosomopathy characterized by immune deficiency, carries a markedly increased risk of early-onset malignancy, particularly lymphoma. However, the molecular drivers of malignant transformation in CHH, and the contribution of viruses to this process, remain poorly defined. Methods We performed targeted virome sequencing of 41 DNA viruses on FFPE tumor samples (primarily lymphomas) from 15 CHH patients and three malignancy-matched controls per patient. Subseque …