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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

World Journal of Gastrointestinal Surgery

Predictors of the technical success of ultrasound-guided percutaneous transhepatic biliary drainage for biliary obstruction

Yun Song, Guang-Hai Chen, Lu Peng, Jian Du, Shu-Ming Tan

BACKGROUND Percutaneous transhepatic biliary drainage (PTBD) is a critical minimally invasive intervention for biliary obstruction, with technical success being a key determinant of clinical outcomes. AIM To identify and quantify the clinically modifiable factors predicting technical success of ultrasound-guided PTBD, and thereby to develop an evidence-based framework for procedural triage and standardization. METHODS A total of 263 ultrasound-guided PTBD procedures performed at three tertiary hospitals (2019-2024) …

27.08.2026journal-article

Journal of Pediatric Orthopaedics B

Radiological and clinical outcomes following pelvic support osteotomy with limb length equalization in children

Vikaas Ethanur Thuppale, Arulmurugan Arikrishnan, Jonathan Reddy, Abhay Gahukamble, Thomas Palocaren

Pelvic support osteotomy (PSO), when done in children, is subject to remodeling. This study aimed to assess the extent of remodeling at the osteotomy site and functional outcome post-PSO. A total of 28 patients were selected with a minimum follow-up of 2 years. PSO was combined with limb length equalization procedures including distal femoral lengthening, epiphysiodesis, or shoe raise, as indicated, because all patients had limb length discrepancy as part of their underlying pathology. The valgus osteotomy angle in …

27.08.2026journal-article

Nursing Ethics

Neonatal nurses’ moral agency in raising medication and treatment safety concerns in high-risk NICUs

Osama Mohamed Elsayed Ramadan, Manar Fayez Alruwaili, Reda Samy, Hamda Ahmed Mohamed Eldesoky, Ghada Elsaid Ali Elsayed

Background In neonatal intensive care units (NICUs), nurses may recognise medication or treatment risk before others do. Raising a concern is an ethical act, but moral agency extends beyond voice behaviour. Research question/aim/objectives How do neonatal nurses experience and enact moral agency when raising medication and treatment concerns in high-risk NICUs? We examined risk recognition, enactment of voice, contextual influences, and responsibility after voice. Research design Qualitative Interpretive Descriptio …

27.08.2026journal-article

HIV Medicine

Wellbeing of trans and gender‐diverse people with HIV in the United Kingdom: Results from Positive Voices 2022

H. Kitt, C. Kelly, A. Aghaizu, M. Ross, F. C. Lampe, C. J. Smith, V. Martin, C. Humphreys, A. Brown, A. Sparrowhawk, M. Kall, J. Sewell, E. Wainwright, V. Delpech, G. Davis, A. Farah, A. Fasanya, A. J. Rodger, T. Đuretić, PV2022 Study Group

Abstract Objectives This national cross‐sectional observational study aimed to assess mental health, quality of life, supportive network, experiences of HIV‐related stigma in healthcare and unmet service need among trans and gender‐diverse people with HIV, compared to cisgender people with HIV. Methods Positive Voices 2022 is a questionnaire survey of people accessing HIV care in England, Scotland and Wales carried out in 2022 and 2023 that included measures of depression and anxiety symptoms and suicidal ideation …

27.08.2026journal-article

Journal of Intensive Care Medicine

Acute Severe Asthma in the Intensive Care Unit: From Bronchodilators to Extracorporeal Membrane Oxygenation

Parisa Abedi, Geoffrey Chupp, Gabriella Wilson, Sandra Zaeh, Astha Chichra

Acute severe asthma exacerbations are life-threatening critical care emergencies characterized by profound airflow obstruction, respiratory acidosis, and risk for cardiopulmonary arrest. For the purposes of this review, the term ‘acute severe asthma’ is used to encompass what has variably been described as near-fatal asthma, status asthmaticus, and life-threatening asthma in the literature. Early recognition of impending respiratory failure, timely intubation and a stepwise approach to supportive interventions are …

27.08.2026journal-article

Measurement Science and Technology

Fault diagnosis of connection loosening in fast-swapping battery case for electric heavy trucks based on vibration-electric signal synergy

Yifan Zheng, Xianglong You, Yuepan Lv, Minzhang Zhao, Zhuohang Han, Jianjuan Liu, Hang Yuan

Abstract As the core energy storage unit of fast-swappable battery cases in electric heavy trucks, power batteries are particularly prone to connection loosening faults under complex operating conditions, such as frequent battery swapping, continuous vibration, and mechanical shocks. These faults are highly concealed and difficult to detect at an early stage, posing significant challenges for fault detection and diagnosis. To address this issue, this study proposes a vibration-electric synergy-based method for faul …

27.08.2026journal-article

RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren

Pediatric Vascular Anomalies in a Specialized Interdisciplinary Center: A 10-Year Cohort Analysis of Diagnosis, Imaging, and Treatment Pathways

Céline Gärtner, Haneen Sadick, Felix Struebing, Daniel Svoboda, Anke Dippmar, Christel Weiss, Klaus Amendt, Maliha Sadick

Abstract This study uses original data from a 10-year cohort analysis of diagnosis, imaging, and treatment pathways in pediatric vascular anomalies at a specialized interdisciplinary center. The study examines the role of radiology in establishing diagnostic and therapeutic algorithms for interdisciplinary management of children with vascular anomalies. A total of 331 children were included in this study. Patient characteristics, the location, and anatomical site of the vascular anomaly and associated pain levels w …

27.08.2026journal-article

Healthcare

Regular AREDS2 Supplement Use in Age-Related Macular Degeneration: Factors Associated with Supplementation, Medication Adherence, and Patient-Reported Barriers

Hasan Öncül, Umut Dağ, Mehmet Fuat Alakuş

Background/Objectives: Age-related macular degeneration (AMD) is a leading cause of irreversible visual impairment, and AREDS2-based nutritional supplementation is recommended for clinically eligible patients to reduce the risk of disease progression. However, successful implementation depends on regular supplement use and sustained adherence. This study investigated demographic, socioeconomic, clinical, and physician-related factors associated with regular AREDS2 supplement use and evaluated medication adherence, …

27.08.2026journal-article

Neuro-Oncology

59 Early psychosocial support after a brain tumour diagnosis: a collaborative model between Southmead Hospital and Brain Tumour Support

Lucy Wilkinson, Emma McKeown

Abstract Introduction A pilot referral pathway between Southmead Hospital and Brain Tumour Support (BTS) was introduced to provide early psychosocial support to patients diagnosed with a brain tumour and their families. This evaluation assessed uptake, perceived value, and service impact. Method Over six months, 115 patients and family members were referred to BTS; 10 declined or did not respond. Referrals included newly diagnosed patients, individuals undergoing investigations and supporting relatives. Tumour type …

27.08.2026journal-article

Journal of Clinical Medicine

A Decade of Data from an IVF Center: Factors Contributing to Infertility, Their Prevalence, and Impact on Live Birth Rates

Hale Bayram, Yaprak Dönmez Çakıl, Belgin Selam, Mehmet Cıncık

Background: Infertility is increasingly recognized as a significant global public health concern. A thorough understanding of the diverse causes of infertility and their influence on treatment outcomes is essential for optimizing therapeutic strategies and improving success rates. Methods: In this study, we analyzed data from 9132 couples who underwent IVF treatment at a fertility center in Istanbul, Turkey, between 2010 and 2020. Results: Female factor infertility was the most prevalent among all participants (35. …

27.08.2026journal-article

American Journal of Hematology

Impact of Response to Hypomethylating Agent‐Based Therapy on Survival Outcomes in the Context of Baseline Clinical‐Molecular Risk and Transplant Status in Patients With Higher‐Risk Myelodysplastic Syndromes/Neoplasms: An analysis From the International Consortium for MDS (icMDS)

Benjamin Rolles, Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Jessica M. Stempel, Luca Lanino, Najla H. Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L. Uy, Samuel Urrutia, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Christine McMahon, Rory M. Shallis, Joshua F. Zeidner, Michael R. Savona, Shougat Barua, Namrata Sonia Chandhok, Constantine Logothetis, Aram Bidikian, Ted M. Getz, Gail J. Roboz, Eunice S. Wang, Amyah C. Harris, Maria L. Amaya, Hayley Hawkins, Somedeb Ball, Justin Grenet, Parisa Abedi, Shai Shimony, R. Coleman Lindsley, Zhuoer Xie, Yazan F. Madanat, Yasmin Abaza, Talha Badar, Torsten Haferlach

ABSTRACT Baseline IPSS‐M risk, response to hypomethylating agent (HMA) therapy, and receipt of allogeneic stem cell transplant (allo‐HCT) have all been individually shown to impact overall survival (OS) in patients with myelodysplastic syndromes (MDS). However, the prognostic impact of response when adjusting for IPSS‐M risk and treatment strategy remains unclear. Hence, we used the VALIDATE database of the International Consortium for MDS (icMDS) to evaluate the impact of International Working Group (IWG) 2023 bes …

27.08.2026journal-article

The American Journal of Tropical Medicine and Hygiene

Multistakeholder Consultations on Programmatic Progress, Challenges, and Policy Priorities for Lymphatic Filariasis Elimination in India

Muhammed Jabir, Raja Jeyapal Dinesh, Adinarayanan Srividya, Anju Viswan, Manikandan Kishanthini, Richa Sharma, Manju Rahi

ABSTRACT. This report presents the key proceedings and outcomes of three regional consultative workshops convened to review progress, identify challenges, and propose strategic actions for lymphatic filariasis elimination in India. The workshops were organized by the Indian Council of Medical Research-Vector Control Research Centre, Puducherry in collaboration with the Women’s Collective Forum, New Delhi from June 2025 to August 2025. Consultations were held in three endemic states representing different regions of …

27.08.2026journal-article

The American Journal of Tropical Medicine and Hygiene

Malaria Vaccine Rollout in Nigeria: Current Status and Challenges

Samuel Adeniyi Oyegbade, Samson Olusola Adeboye, Gbotemi Jerry Oni, Abosede Peace Oyegbade, James Joy Oziohu, Zawu Yoowa Duyann, Oluwatoyin Comfort Owoyemi

ABSTRACT. Malaria remains a leading cause of morbidity and mortality in Nigeria, particularly among children under 5 years of age, despite ongoing control efforts. The introduction of RTS,S/AS01, and R21/Matrix-M vaccines provides a promising complementary prevention strategy. This systematic review assessed malaria vaccine rollout in Nigeria, focusing on implementation, awareness, acceptance, willingness to pay, and health system readiness. A comprehensive search of PubMed, ScienceDirect, Google Scholar, African I …

27.08.2026journal-article

Revista ft

Segurança do paciente: estratégias de enfermagem para prevenção de erros na administração de medicamentos

Marcos Leal Rodrigues Pereira, Gerson Luiz Pereira Emerim da Silva, João Lucas Vaz Macedo, Leandro Ghilardi

This study aimed to analyze the nursing strategies used to prevent medication administration errors and promote patient safety. This is an integrative literature review conducted in the SciELO, LILACS, MEDLINE/PubMed, BDENF, and DOAJ databases, considering publications from January 2020 to July 2026 in Portuguese, English, and Spanish. The initial search identified 18 studies, of which 8 comprised the final sample after application of the inclusion and exclusion criteria. The main strategies identified included con …

27.08.2026journal-article

Evolution, Medicine, and Public Health

Running wild: Forest running enhances performance, enjoyment, mood and future exercise intentions

Matthew J Putland, Stephen J Bailey, Bryna C R Chrismas, Stacy Clemes, Morgan Ewers, Yu-Ling Ho, Eloise Jones, Adelina Lintuluoto, Kirsten McEwan, Riddhi Naik, Hanna Lal Rahimi, Hongbin Xiang, Erik P Willems, Colin N Shaw, Daniel P Longman

ABSTRACT Background and objectives Physical inactivity remains widespread despite the well-established physical and mental health benefits of regular physical activity (PA). There is an urgent need for strategies that increase both uptake and long-term adherence. The Environmental Mismatch Hypothesis proposes that natural environments may increase both engagement and performance of PA. Methodology Forty-seven healthy adults (16 females) completed a randomised, counterbalanced crossover trial. Participants undertook …

27.08.2026journal-article

Frontiers in Public Health

Psychological capital, perceptions of clinical stressors, and bullying experiences among Chinese nursing students during clinical practice: a latent profile and mediation analysis

Fangfei Zhao, Hongchen Zhang, Ke Hui, Haixin Zheng, Zhihui He

Background Bullying experiences during clinical practice threaten nursing students' learning and professional development. However, existing studies mainly focused on variable-centered associations, with limited exploration of heterogeneous subgroups from a person-centered perspective. This study aimed to examine the mediating role of perceptions of clinical stressors (PCS) in the relationship between psychological capital (PsyCap) and bullying experiences, while identifying latent profiles of bullying experiences. …

27.08.2026journal-article

Indonesian Journal of Innovation Multidisipliner Research

The Role of Platelet Count and Hematocrit as Biomarkers in the Diagnosis of Dengue Hemorrhagic Fever in Pediatric Patients at RA Kartini General Hospital, Jepara

Firda Amalia Putri Fiandy, Rido Muid Riambodo, Fatinah Shahab, Selvi Mella Maharani

Background: Dengue Hemorrhagic Fever (DHF) remains a major pediatric health problem in Indonesia, one of the countries with the highest disease burden globally. Platelet count and hematocrit are routinely used laboratory parameters believed to reflect disease severity through mechanisms of platelet destruction and plasma leakage, respectively, yet their individual diagnostic value continues to be debated across the literature. Objective: To analyze the role of platelet count and hematocrit as biomarkers in diagnosi …

27.08.2026journal-article

Arab Media Renewal Journal

معالجة الأزمات الإنسانية في الصحافة الرقمية المصرية والأمريكية: دراسة تحليلية مقارنة

شروق حسنين قاسم

استهدفت الدراسة رصد وتحليل معالجة الصحافة الرقمية الأمريكية والمصرية للأزمات الإنسانية، بالتطبيق على موقعَي «اليوم السابع» المصري، و»USA Today» الأمريكي، وذلك في إطار نظرية المسؤولية الاجتماعية، ونظرية المشاركة الديمقراطية. وقد اعتمدت الدراسة على استخدام منهج المسح، وأسلوب المقارنة المنهجية، بالاعتماد على استمارة تحليل المضمون لجمع بيانات الدراسة، التي شملت (603) موضوعًا صحفيًا إنسانيًا تم نشرها خلال فترتين زمنيتين مختلفتين، هما (يناير-أبريل 2017) و(يناير-أبريل 2022) بموقعي الدراسة.وأظهرت النتائج تقاربًا في الحجم ا …

27.08.2026journal-article

World Journal of Gastrointestinal Surgery

Prognostic factors of sepsis following laparoscopic hiatal hernia repair

Hong Yu, Jun-Ying Xu, Ya-Ru Zhang, Xiao-Bing Zhou, Han-Rong Zuo, Zhi Li

BACKGROUND Laparoscopic hiatal hernia repair (LHHR) is the surgical intervention of choice for symptomatic hiatal hernias; however, a major complication such as postoperative sepsis presents a serious challenge, particularly in elderly and comorbid patients. Acute kidney injury (AKI) occurring in patients with sepsis is termed sepsis-associated AKI. This complication has been reported to affect 40%–50% of intensive care unit patients with sepsis and is an independent risk factor for increased mortality and prolonge …

27.08.2026journal-article

Frontiers in Neurology

Clinical features associated with cerebrospinal fluid Epstein–Barr virus positivity in autoimmune GFAP astrocytopathy: a multicenter retrospective cohort study

Xing Mao, Qianqian Qu, Chao Quan, Haidong Lyu, Jingzi Zhangbao, Xuan Wang, Hongmei Tan, Xiang Li

Background Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is an inflammatory disorder of the central nervous system. The clinical implications of Epstein–Barr virus (EBV) sequences detected in cerebrospinal fluid (CSF) by metagenomic next-generation sequencing (mNGS) remain uncertain. Methods This multicenter retrospective cohort study enrolled 60 patients with GFAP-A screened from electronic medical records of two hospitals (Jan 2019–Dec 2025). Patients were stratified into CSF EBV-positive ( n …

27.08.2026journal-article

Frontiers in Medicine

The proteomic architecture of clonal hematopoiesis: a systematic review of niche remodeling and multi-compartment predictors of malignant transformation

Jana H. Husein, Rasha M. Khayata, Aisha Jahangir, Ghaith K. Mansour, Ahmed W. Hajjar, Muhammad Raihan Sajid

Background Clonal hematopoiesis of indeterminate potential (CHIP) is a precursor to myeloid malignancies, yet the functional proteomic landscape that governs clonal fitness and microenvironmental remodeling remains poorly understood. This systematic review consolidates high-resolution proteomic evidence to map the transition from stable CHIP to overt malignancy. Methods Following PRISMA 2020 guidelines, we analyzed 15 high-quality studies (selected from 83 initial records) published between 2015 and 2025. The revie …

27.08.2026journal-article

Frontiers in Medicine

Severe recurrent hypernatremia and probable lithium-associated nephrogenic diabetes insipidus following pancreatectomy in a patient with schizophrenia: a case report

Yanfei He, Liuyin Jin, Xiaolei Xu, Qing Xia

Background Nephrogenic diabetes insipidus (NDI) is characterized by impaired renal responsiveness to arginine vasopressin, causing defective urinary concentration and large volumes of dilute urine. Long-term lithium exposure is an important acquired cause. Perioperative fasting, restricted free-water intake, and ongoing fluid losses may unmask compensated lithium-associated urinary concentrating dysfunction and precipitate severe hypernatremia. Case presentation A 61-year-old man underwent laparoscopic resection of …

27.08.2026journal-article

The American Journal of Tropical Medicine and Hygiene

Monitoring Cholera Transmission in Zambia Using the Cholera Elimination Scorecard

Caroline C. Chisenga, Lilian Lamba, Charlie C. Luchen, Ashley Duncan, Nyuma Mbewe, Masuzyo Zyambo, Maisa Kasanga, Fraser Liswaniso, Harriet Ng’ombe, Michelo Simuyandi, Amanda K. Debes, Roma Chilengi, David A. Sack

ABSTRACT. We used the cholera elimination scorecard to better understand the changing cholera patterns in Zambia. The method used surveillance data from the Zambia National Public Health Institute to identify districts that had eliminated cholera or continued to be endemic between 2015 and 2024. Between 2017 and 2022 the number of cholera-endemic districts decreased from 27 to 6; however, in 2023 and 2024, a severe outbreak occurred in Lusaka and expanded to neighboring districts. Concurrently, a separate outbreak …

27.08.2026journal-article

The Journal of Clinical Endocrinology & Metabolism

Neuroimaging Abnormalities and Genotype-Phenotype Correlations in Noonan Syndrome: A Multicenter Cohort Study

Giuseppa Patti, Nadia Gabriella Maiorano, Francesca Piccoli, Alice Zucconi, Maria Grazia Calevo, Federica Tamburrino, Emanuela Scarano, Concetta Schiavariello, Cesare Rossi, Laura Mazzanti, Eleonora Orlandini, Gabriella Pozzobon, Martina Finamore, Cristina Baldoli, Anna Grandone, Mario Cirillo, Francesca Aiello, Domenico Corica, Malgorzata Wasniewska, Alessandro Cattoni, Paolo Remida, Donatella Capalbo, Fabio Tortora, Maria Carolina Salerno, Sara Azzolini, Mariam Mansour, Maria Felicia Faienza, Stefano Palladino, Domenico Tortora, Giulia Rosti, Francesca Faravelli, Cristina Venturino, Pasquale Capuozzo, Letizia De Mori, Paola Maietta, Anna Elsa Maria Allegri, Chiara Morreale, Alessia Angelelli, Flavia Napoli, Natascia Di Iorgi

Abstract Context Neuroradiological findings in Noonan syndrome (NS) remain insufficiently characterized Objective To characterize neuroimaging abnormalities in children with genetically confirmed NS and evaluate their associations with clinical phenotype Design, Setting, and Participants In this multicenter retrospective study, brain MRI scans and longitudinal clinical and genetic data were reviewed from children with genetically confirmed NS evaluated between 2008 and 2023 at seven pediatric endocrinology centers …