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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Hacettepe University Faculty of Health Sciences Journal

Odyologların Demans, Bilişsel Tarama ve Demanslı Hastaya Odyolojik Yaklaşım Hakkındaki Bilgi ve Görüşlerinin İncelenmesi

Merve Deniz Sakarya

Amaç: Çalışmanın amacı odyologların, demans tanısı ya da şüphesi olan yaşlılarla çalışma deneyimlerini incelemek, bilişsel tarama hakkındaki bilgi ve görüşlerini saptamak ve demanstan şüphelenildiği durumlarda uygulamada yaptıkları değişiklikleri ortaya koymaktır.Gereç ve Yöntem: Çalışmaya 23-50 yaş arası, 112’si kadın (%74,2) ve 39’u erkek (%25,8) olmak üzere toplam 151 odyolog/odyoloji ve konuşma bozuklukları uzmanı katılmıştır. Çalışmanın verileri online anket formu ile toplanmıştır. Anket “odyologların demanslı …

28.08.2026journal-article

PLOS One

Prevalence of mental health, mental well-being, and school connectedness in UK secondary school students in 2021/2022: Results from the South West - School Health Research Network pilot study

Patricia N. Albers, Emily Widnall, Lorna Hatch, Georgina Hopkins, Catherine Sharp, Judi Kidger, Frank de Vocht, Eileen Kaner, Esther M. F. van Sluijs, Hannah Fairbrother, Russell Jago, Rona Campbell

Background Young people are experiencing more mental health challenges, and connection to school can improve this. This study aimed to investigate adverse mental health, mental well-being, and school connectedness among secondary school students according to gender, academic year group, and socioeconomic status to identify areas for intervention. Methods Self-report questionnaire data from 5193 Year 8 and 10 students (12−15 years) in the UK South West – School Health Research Network (SW-SHRN) were analysed. Weight …

28.08.2026journal-article

Journal of Health Psychology

Neighborhood effects on Black adolescents’ obesity risk: The mediating role of family experiences

Olivenne D. Skinner, Vanessa V. Volpe, Juan Del Toro, April R. Vollmer, Joanna Adamusik

We examined longitudinal associations between neighborhood environments (walkability, area deprivation, and traffic volume) and obesity risk, tested sex differences, and evaluated family experiences as mediators. Participants were 1325 Black youth (52% male; M age = 9.5) and caregivers from the first 3 years of the Adolescent Brain Cognitive Development (ABCD) Study. We used participants’ survey responses and measures of neighborhood context from publicly available sources. Greater neighborhood walkability predicte …

28.08.2026journal-article

Medicine

Pregabalin-associated adverse drug reactions

Fahad S. Alshehri, Ahmed M. Ashour, Nasser M. Alorfi, Abdullah S. Alshehri, Mahdi K. Almahdi, Fahad Mohammad Almowallad

Pregabalin is widely used for neuropathic pain, epilepsy, and anxiety disorders but has become increasingly associated with misuse and dependence. Understanding its global safety profile is essential to support pharmacovigilance and toxicovigilance efforts. This study aimed to characterize the pharmacological and toxicological patterns of pregabalin-related adverse drug reactions (ADRs) reported worldwide, with emphasis on neuropsychiatric toxicity, misuse, and social consequences. A retrospective, descriptive anal …

28.08.2026journal-article

Medicine

Association of the geriatric nutritional risk index with mortality in patients with rheumatoid arthritis

Zhong Wen, Shunbing Wang, Yuzhi Li, Xin Tu, Quanbo Zhang, Yufeng Qing

To investigate the association of the geriatric nutritional risk index (GNRI) with all-cause and cardiovascular mortality among adults with rheumatoid arthritis (RA). Data were obtained from the National Health and Nutrition Examination Survey 2007 to 2018. The GNRI was evaluated continuously and categorically (< 98 vs ≥ 98). Survey-weighted Cox proportional hazards models were used to estimate hazard ratios and 95% confidence intervals (CIs) for all-cause and cardiovascular mortality. Restricted cubic spline, comp …

28.08.2026journal-article

REMUNOM

A APLICAÇÃO DO PENSAMENTO COMPLEXO DE EDGAR MORIN NA MEDICINA E EDUCAÇÃO EM SAÚDE: UMA REVISÃO DE LITERATURA

Renato Faria da Gama, Lilian Coelho Heringer Diniz, Peterson Gonçalves Teixeira, Rodolfo Moura Pereira, Crisóstomo Lima do Nascimento

O modelo biomédico cartesiano, consolidado pelo Relatório Flexner no início do século XX, impôs uma trajetória de hiperespecialização e fragmentação do conhecimento na medicina. Embora tenha propiciado inegáveis avanços tecnológicos, essa abordagem reducionista limitou a capacidade dos profissionais de compreender o paciente em sua totalidade existencial e biopsicossocial. O presente artigo de revisão narrativa analisa as contribuições do Pensamento Complexo de Edgar Morin (1921–2026) como alternativa epistemológic …

28.08.2026journal-article

Frontiers in Medicine

Endocrinology concepts for diabetic retinopathy care: bridging systemic metabolic control with retinal disease management and patient education

Sidney Jones, Peter Koulen

Diabetic retinopathy (DR) is a leading cause of vision loss and a common microvascular complication of diabetes mellitus. Although diagnosis and management are typically guided by retinal findings, systemic metabolic factors—including glycemic control, diabetes duration, blood pressure, renal function, lipid status, and overall complication burden—play a central role in disease development and progression. Clinical decision-making often remains fragmented across endocrinology, primary care, and ophthalmology, contr …

28.08.2026journal-article

Frontiers in Pharmacology

Oral small-molecule GLP-1 receptor agonists: a new Frontier in cardiometabolic medicine

Jinkai Guo, Hua Chen

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have revolutionized the management of type 2 diabetes (T2D) and obesity, with injectable agents demonstrating significant cardiovascular (CV) risk reduction in pivotal trials including LEADER, SELECT, and SUMMIT. However, the reliance on injectable peptide formulations has constrained global accessibility and long-term adherence. The recent emergence of orally bioavailable, nonpeptide, small-molecule GLP-1 RAs—exemplified by orforglipron (Foundayo), danuglipron, …

28.08.2026journal-article

Palliative Medicine

Confronting complexity and unmet need: A qualitative study to inform palliative care service design for adults with multiple long-term conditions

Charlotte Stenson, Felicity Dewhurst, Philip Mordue, Katie Brittain, Mark Adley, Barbara Hanratty

Background: Most people live with and die from multiple long-term conditions. In the last year of life, many receive burdensome care of limited benefit, while access to palliative care remains inconsistent. Improving care for this population would help address inequity because disadvantaged groups are disproportionately affected. Aim: To examine professionals’ perspectives on palliative care needs and end-of-life challenges for people with multiple long-term conditions and their families, and to identify implicatio …

28.08.2026journal-article

Russian Journal of Clinical Dermatology and Venereology

Optimization of systemic isotretinoin dosing in patients with acne at high risk of recurrence

I.M. Khismatulina

Objective. To develop a model for predicting the likelihood of acne recurrence and to compare the efficacy and safety of systemic isotretinoin therapy at doses of 0.5 and 1 mg/kg body mass in patients with a high risk of recurrence. Materials and methods. At the first stage, a predictive model was constructed using logistic regression based on an analysis of clinical, anamnestic, laboratory, and instrumental data from 511 patients. At the second stage, 72 patients with moderate to severe acne and a high risk of rec …

28.08.2026journal-article

Arthritis & Rheumatology

Cancer in systemic sclerosis: clinical associations and prognostic impact from the EUSTAR registry

Antonio Tonutti, Francesca Motta, Liala Moschetti, Cosimo Bruni, Carina Mihai, Claudia Iannone, Maria Rosa Pellico, Stefano Stano, Stefano Erba, Claudia Barison, Eleonora Pazzi, Andrea Benini, Beatrice Moccaldi, Kurszán Jász Dávid, Ágnes Ágoston‐Szabó, Beatrice Gabrielli, Francesca Nava, Dóra Tari, Francesca Romana Di Ciommo, Yuri Sasaki, Gonçalo Boleto, Radim Bečvář, Alejandro Brigante, Britta Maurer, Massimiliano Limonta, Rahma A. Elziaty, Fabiola Atzeni, Lilian Maria López Núñez, Roberta Foti, Francesco Benvenuti, Brigitte Granel, Elena Rezus, Leila Caillault, Sophie Blaise, Cristiana Sieiro Santos, Fabio Cacciapaglia, Roberto Giacomelli, Rossella De Angelis, Serena Guiducci, Duygu Temiz Karadag

Background Cancer represents a major cause of mortality in systemic sclerosis (SSc). Established risk factors are limited to specific subsets, particularly early diffuse anti‐RNA polymerase III (POLR3)‐positive disease, needing further exploration. Methods We performed a nested case‐control study within EUSTAR: cases were SSc patients developing cancer at any timepoint; controls were cancer‐free SSc matched for age and disease duration. Malignancies were classified as synchronous to SSc onset (±3 years), subsequent …

28.08.2026journal-article

Oncology Reviews

Clinical value of combined SHOX2 and RASSF1A methylation in lung cancer diagnosis across tissue and liquid biopsy samples: a systematic review and meta-analysis

Ting Wang, Jianguo Zhang, Jiayang Wang, Xiaoqun Dong, Qiushi Lin, Leiming Guo, Bo Zhang, Yue Cao, Yining Zhai, Mathhew Hadfield, Khan Hina, Abbas E. Abbas, Hong Ge, Liang Cheng, Hang Xing, Yifei Liu

Lung cancer remains the leading cause of cancer-related mortality worldwide, with poor prognosis in advanced stage diseases. Although early diagnosis has the potential to improve patient outcomes, current diagnostic methods remain suboptimal, highlighting the need for accurate molecular biomarkers. We systematically reviewed 49 studies to evaluate the diagnostic performance of SHOX2 methylation, RASSF1A methylation, and their combined panel for lung cancer detection. The combined SHOX2/RASSF1A methylation panel dem …

28.08.2026journal-article

Frontiers in Medicine

Case Report: Reversible neurological involvement associated with Chlamydia psittaci infection: clinical, cerebrospinal fluid and neuroimaging features of three fully documented cases

Hao Zhang, Jia Zhou, Yong Chen, Xiuyan Wang, Xiaoping Luo, Guilan Yang, Zhenzhen Gui, Shuni Wang, Yanan Zhang, Juan Chen

Background Chlamydia psittaci infection presents mainly as severe pneumonia, but a subset of patients develop neurological symptoms. Previous reports are largely single cases and frequently lack cerebrospinal fluid (CSF) data, opening pressure and follow-up imaging, which makes the mechanism of neurological involvement difficult to determine. Methods We retrospectively analysed three patients with C. psittaci infection confirmed by metagenomic next-generation sequencing (mNGS), all of whom developed neurological ma …

28.08.2026journal-article

Informatica

Exploring Public Reaction to Air Quality on Social Media: The 2022 Saharan Dust Episode in Lisbon

Antonino Candeias, Rogério Dionísio, Fernando Ribeiro

This study analyses the relationship between air quality and sentiments expressed on social media, focusing on the Saharan dust episode that affected Lisbon in March 2022. Environmental data were collected alongside geolocated Twitter posts (now rebranded as X) from the Lisbon area. The content of these posts was analysed using the Valence Aware Dictionary and sEntiment Reasoner algorithm to identify emotional patterns and assess correlations with fluctuations in atmospheric pollutants. A predictive analysis was al …

28.08.2026journal-article

Journal of Clinical Medicine

Association Between the Number of Metabolic Syndrome Components and Markers of Subclinical Vascular Damage: A Retrospective Cross-Sectional Study

Monika Starzak, Grzegorz K. Jakubiak, Natalia Pawlas, Grzegorz Cieślar, Agata Stanek

Background: Metabolic syndrome (MetS) refers to the coexistence of cardiometabolic disorders, such as hyperglycemia, elevated blood pressure, visceral obesity, or features of atherogenic dyslipidemia. A diagnosis of MetS significantly increases the risk of cardiovascular disease (CVD). However, the exact relationship between the number of MetS components, regardless of their constellation, and features of subclinical cardiovascular dysfunction remains unclear. This study aimed to explore the relationship between th …

28.08.2026journal-article

Education in Medicine Journal

Evaluating the Perceived Quality of Educational Services Among Clinical Pathology Residents in Hasanuddin University Using the SERVQUAL Instrument

Kartika Paramita, Andi Alfian Zainuddin, Berti Nelwan, Budu, Irfan Idris, Agussalim Bukhari

The SERVQUAL instrument is widely used to assess service quality across various sectors; however, its application in specialist medical education remains limited. This study evaluated the educational service quality of the Clinical Pathology Specialist Programme at Hasanuddin University, Indonesia, from the residents’ perspective using the SERVQUAL model. Out of 84 residents, 64 completed thestandardised questionnaire measuring five service dimensions: reliability, assurance, tangibles, responsiveness, and empathy. …

28.08.2026journal-article

Clinical and Experimental Dermatology

Effectiveness, safety and tolerability of Ozenoxacin 2% lotion vs Clindamycin 1% lotion in mild to moderate truncal acne: An open label randomized controlled clinical trial

Anupam Das, Sambit Chatterjee, Saikat Banerjee, Sujata Sengupta

Abstract Background Truncal acne is a frequently encountered but relatively understudied manifestation of acne vulgaris and is often associated with significant physical discomfort and psychosocial impact. Topical clindamycin has been extensively used in mild to moderate acne, however, there are concerns regarding antimicrobial resistance which has prompted interest in alternative topical agents. Ozenoxacin, a non-fluorinated quinolone, offers broad-spectrum antibacterial activity with minimal systemic absorption. …

28.08.2026journal-article

Discover Artificial Intelligence

A responsible artificial intelligence framework for translational readiness of machine learning biomarker models in clinical decision support

Vahid Habibzadehomran

Abstract Machine learning (ML) has expanded biomarker modelling across molecular, imaging, laboratory, electronic health record, and multimodal data, yet strong retrospective performance does not by itself establish clinical readiness. This structured narrative review examines the evidence required to translate ML-based biomarker models into clinical decision-support systems. PubMed, Scopus, Web of Science, and Google Scholar were searched for peer-reviewed literature addressing biomarker validation, external valid …

28.08.2026journal-article

Eduvest - Journal of Universal Studies

Enforcement and Return of Evidence by the Public Prosecutor Following a Judge’s Decision to Grant Pardon

Natasya Audrey Christin Br. Marpaung, R.B. Sularto

This study addresses the legal uncertainty surrounding the execution and return of evidence following a judicial pardon (Rechterlijk Pardon) under Indonesia’s renewed criminal law framework. Although judicial pardon represents a shift toward restorative justice, the absence of specific prosecutorial procedures for implementing such decisions creates a normative gap, particularly when evidence must be returned to different entitled parties. This study aimed to analyze the normative position and authority of the Publ …

28.08.2026journal-article

Journal of Prevention

Temporal Data Structure Is Not Causal Identification: A Practical Framework for Appraising Causal Claims in Prevention and Population Health Research

Sunday Azagba, Galappaththige S. R. de Silva

Abstract Temporal data structure is not an identification strategy. In manuscript review and reporting, cross-sectional and longitudinal labels are sometimes used as shorthand for judging whether causal claims are appropriate. Whether a causal claim is credible depends on the effect being considered, what makes the comparison informative, what assumptions are required, and whether the analysis and supporting evidence address the main threats. We define temporal data structure as the temporal and sampling organizati …

28.08.2026journal-article

Interactive Journal of Medical Research

How Many Instruments Do We Need? Strengths, Weaknesses, and Potentials for Further Developments of Digital Health Literacy Measurement Instruments: Narrative Overview of Reviews and Content Analysis

Pauline Kaboth, Lorenz Harst, Jochen Schmitt, Madlen Scheibe

Abstract Background With the ongoing digitalization of health care, digital health literacy (DHL) is becoming increasingly important, requiring appropriate measurement instruments (DHLMIs). However, the wide range of available DHLMIs makes selection difficult and raises questions about their suitability and comparability. Objective This review aimed to provide an overview of available DHLMIs for adult populations and to compare their dimensions, identifying overlaps and differences to determine which (key) dimensio …

28.08.2026journal-article

International Journal of Sports Medicine

Regional Muscle Architecture and Bench Press Performance in Paralympic Powerlifting

Marcelo D.M. dos Santos, Bruno F. Rodrigues, Felipe J. Aidar, Lucas T. Lacerda, Andressa Silva, Marco T. Mello, Fernando V. Lima, Mauro H. Chagas, Maicon R. Albuquerque, Rodrigo C.R. Diniz

Abstract This study investigated the magnitude of the association of the regional muscular architecture of the pectoralis major and triceps brachii muscles on the maximum dynamic strength in Paralympic powerlifting athletes. Twenty-six athletes participated in this study. Architectural analysis included cross-sectional area and muscle thickness of the pectoralis major at 15 and 30% of the clavicle length and of the triceps brachii at 50, 60 and 70% of the humerus length, in addition to the pennation angle and fasci …

28.08.2026journal-article

Journal of Indian Association for Child and Adolescent Mental Health

Developing Coping Strategies Through Rhythmic Physical Activity Among Children with Mild Intellectual Disability to Enhance Sociability

M. Mary Glory Ponrani, Dilshith Azeezul Kabeer, Vinolia B, Vinu W.

Background: Children with mild intellectual disability (ID) tend to have problems with emotional regulation, neuromotor responsiveness, and social functioning. Rhythmic physical activity (RPA) is a structured movement with auditory feedback that has demonstrated the possibility to improve developmental outcomes in neurodiverse populations. Objectives: The purpose of this study was to investigate the impact of a 16-week RPA intervention on coping skills, reaction time (RT), and sociability in children with mild ID. …

28.08.2026journal-article

Public Health Journal

Penicillin G Acylase sebagai Biokatalis Dalam Sintesis Enzimatis Antibiotik Beta-Laktam

Wiwin Try Ayu Rombe, Iin Hardiyati, Susi Kusumaningrum, Ahmad Wibisana, Errol Rakhmad Noordam, Salma Hilmy Rusydi Hashim

Antibiotik $\beta$-laktam banyak digunakan dalam terapi infeksi bakteri, namun produksi kimiawinya menghasilkan limbah tinggi dan menggunakan bahan berbahaya. Penicillin G acylase (PGA) menjadi biokatalis kunci untuk hidrolisis penisilin G menjadi asam 6-aminopenisilanat (6-APA) serta sintesis antibiotik semisintetik seperti ampisilin dan amoksisilin. Kajian literatur ilmiah 2015–2025 ini bertujuan menganalisis karakteristik, mekanisme katalitik, dan strategi peningkatan kinerja PGA dalam sintesis enzimatis antibio …