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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
17.08.2026journal-article

FPOP Bulletin: Psychology of Older People

Supporting people living with dementia in care homes: The Distressed Behaviours Pathway

Rebecca Kelly, Julie Braithwaite, Nell Spray

Formulation-led, non-pharmacological support can be beneficial for people living with dementia who experience distressed behaviours within care home settings. As recommended by the National Institute for Health and Care Excellence guidance (NICE, 2018), the Distressed Behaviours Pathway offers a holistic understanding of a person’s distress as well as support with non-pharmacological interventions. The pathway contains various stages wherein the intervention ‘intensity’ is increased as needed. There are many challe …

17.08.2026journal-article

International Journal of Environmental Research and Public Health

Body Composition, Strength, Mobility, and Posture Associated with Shoulder Pain and Disability in Community-Dwelling Older Adults: A Narrative Review

Yarin Gohar, Ella Been, Leonid Kalichman

Shoulder pain ranks among the leading causes of functional decline in older adults, affecting approximately one in five community-dwelling individuals and contributing to loss of independence and reduced quality of life. Despite its prevalence, shoulder pain in this population is frequently underreported and poorly understood beyond structural pathology, limiting early identification and targeted intervention. This narrative review synthesizes current evidence on the associations between four interrelated physical …

17.08.2026journal-article

Gerontology

Mitochondrial Dysfunction as a Central Hub of Aging: From Molecular Cascades to Inter-Organ Communication Networks

Chaodong Han, Zilian Zhang, Yafeng Song

: Background: Mitochondrial dysfunction serves as a fundamental driver of the aging process, precipitating progressive functional decline through complex molecular cascades. Summary: This review elucidates the core mechanisms underpinning this dysfunction, including reactive oxygen species (ROS)-induced redox imbalance, mitochondrial DNA (mtDNA) damage accumulation, impaired mitophagy, and metabolic reprogramming. Crucially, we examine how mitochondria act as signaling hubs for inter-organ crosstalk. Through the se …

17.08.2026journal-article

The Journal of Cardiovascular Aging

Noncoding RNAs in cardiovascular aging and diseases

Bingchuan Geng, Peng Chen, Deqiang Li, Ruili Xie, Timothy M Pawlik, Hua Zhu

This review comprehensively explores the roles of noncoding RNAs (ncRNAs) in cardiovascular diseases (CVDs), highlighting their involvement in major pathological programs and cellular functions. The diverse types of ncRNAs, including microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs), and their mechanisms in regulating gene expression and cellular functions are reviewed. We also examine the potential of ncRNAs as diagnostic biomarkers and therapeutic targets, emphasizing recent advancem …

17.08.2026journal-article

Journal of Organizational Effectiveness: People and Performance

Neurodivergence brilliance: unveiling the power of ADHD traits as catalysts for leadership potential, citizenship behaviour and performance

Mansi Tiwari, Sudarshana Sharma, Yash Vaghela, Osama Khassawneh

Purpose This study investigates the influence of attention-deficit hyperactivity disorder (ADHD) traits (hyperactivity, in-attention and impulsivity) on leadership potential (LP), citizenship behaviour and employee performances. Design/methodology/approach Data for the current research paper are collected from 157 employees working across different organizations operating in Gujarat, India. Researcher used partial least square structural equation modelling SmartPLS 4.1.0.9 version to test the proposed hypotheses. F …

17.08.2026journal-article

Journal of Creating Value

It Is About Young People: How Poverty, Demographic Structure, Cultural Participation, Creative Labour and Digital Engagement Shaped the Recovery of London’s Performing Arts Institutions Following the COVID-19 Pandemic

Tolu Olarewaju, Sanjib Sherpa

Drawing on borough-level socio-economic and demographic data matched with organizational financial records, we analyse the moderating role of average age in the relationship between local poverty and the performance of performing arts institutions following the COVID-19 pandemic. The findings indicate that poverty rates are negatively associated with return on assets; however, performing arts institutions located in boroughs with younger population profiles exhibited greater resilience. Qualitative analysis further …

17.08.2026journal-article

Geriatrics

How Gut Microbiota Influence Healthy Aging: Overview of Reviews

Tejas Ganesh Todmal, Rabia Bibi, Giovanni Cangelosi, Massimiliano Panella, Alice Masini

Background: Gut microbiota plays a key role in the aging process, with age-related microbial shifts contributing to chronic inflammation, metabolic dysfunction, frailty, and cognitive decline. Despite growing interest, an integrated synthesis of how diet and lifestyle modifications influence gut microbiota remains limited. This overview of reviews summarizes the current evidence on how dietary and lifestyle interventions shape microbial composition and affect aging outcomes. Methods: Following the PRISMA guidelines …

17.08.2026journal-article

Otolaryngology–Head and Neck Surgery

Management Patterns and Outcomes of Vestibular Schwannoma in Older Adults: Assessment of the SEER Database

Garin Griffith, Jacob Gould, Saarang Patel, Noah Yaffe, Guan Li, Julian L. Gendreau

Abstract Objective Vestibular schwannoma (VS) is a benign intracranial tumor that is increasingly diagnosed in older adults. The relative contributions of tumor burden and surgical management to overall survival in elderly and very elderly patients remain incompletely characterized at a population level in VS patients. Study Design Retrospective Cohort. Setting SEER Database study between the years 2000 and 2022 to identify patients aged 70 to 89 years diagnosed with VS. Methods Patients were stratified into very e …

17.08.2026journal-article

Medical Care

Impact of Geriatrics Comanagement on Pain Medication Prescribing for Older Adults Across 3 Surgical Specialties

Mark J. Simone, Seyoun Kim, Ingrid M. Nembhard, Lisa M. Walke

Background: Older injured patients are at risk for inappropriate pain management, including undertreatment of their pain and inappropriate medication use. The primary aim of this study was to examine the impact of geriatric comanagement on pain medication prescribing in hospitalized older adults. Setting: Single-site urban academic hospital. Participants: Patients aged 65 years and older admitted to orthopedic trauma, general trauma, and neurosurgery services. Methods: Pre-post intervention study from 2017 to 2020, …

17.08.2026journal-article

Journal of Clinical Medicine

Stress Response During a Three-Month Follow-Up of a Historical Cohort of People with Cancer: Subjective Hyper-Energy and the DYMERS Framework for a Future Preventive Approach

Federica Sancassiani, Goce Kalcev, Elisa Pintus, Stefano Lorrai, Elisa Cantone, Clelia Madeddu, Olga Mulas, Giovanni Caocci, Sergio Machado, Marco Cruciata, Angela Muscettola, Rosangela Caruso, Maria Giulia Nanni, Martino Belvederi Murri, Luigi Grassi, Mauro Giovanni Carta

Background: This study examined whether baseline subjective hyper-energy was associated with depressive symptom changes over three months in people with cancer. Methods: This secondary exploratory analysis used a historical oncology cohort of 263 participants. Subjective hyper-energy was defined using SF-12 (Short Form Health Survey 12-item) item 10, and depressive symptoms were assessed with the PHQ-9 (Patient Health Questionnaire, 9-item) at baseline and follow-up. Inverse-probability weighting (IPW) examined att …

17.08.2026journal-article

FPOP Bulletin: Psychology of Older People

Mechanisms of change in the non-pharmacological treatment of behavioural expressions of need

Ian A. James, Katharina Reichelt

Whatever form of therapy one employs, it is important to have a good understanding of the mechanisms of change and the techniques that bring about improved wellbeing. The ‘mechanisms of change’ refer to the active ingredients undertaken by the professional caregivers that lead to reductions in agitation and distress. Typically, there are two mechanisms: (i) the therapeutic procedures used to bring about helpful changes; and (ii) the clinicians’ processes, that is, actions and behaviours, that directly lead to posit …

17.08.2026journal-article

American Journal of Physiology-Cell Physiology

Combination therapy of RAS inhibition and glucagon-like peptide-1 receptor agonist improves a marker of kidney fibrosis in people with type 2 diabetes

Alexandra L. Møller, Stefanie Thöni, Felix Keller, Samir Sharifli, Federica Genovese, Morten Karsdal, Daniel G. K. Rasmussen, Gert Mayer

In type 2 diabetes (T2D), kidney fibrosis drives the progression of chronic kidney disease (CKD) and kidney failure. Lower urinary levels of collagen type III degradation (C3M), a biomarker of extracellular matrix (ECM) turnover, have been associated with CKD progression. We investigated the effect of combination therapy with renin-angiotensin system inhibition (RASi) and glucagon-like peptide-1 receptor agonist (GLP-1 RA) on urinary C3M levels in people with T2D. Urinary C3M was measured using the nordicC3M™ ELISA …

17.08.2026journal-article

Veterinary Sciences

Sexual Dimorphism and Aging Effects on Pituitary Gonadotroph Structure and Secretion in Dromedary Camels: Immunohistochemical and Ultrastructural Insights

Shaukat Ali Shaukat Jaspal, Hanan Al-Khalaifah, Muhammad Mubashar Shaukat, Robina Shaukat, Tahmina Shaukat, Shabana Naz, Rifat Ullah Khan, Vincenzo Tufarelli, Caterina Losacco, Luciana Rossi, Mutassim M. Abdelrahman

This study investigated age- and sex-related variations in pituitary gonadotroph morphometry and serum luteinizing hormone (LH) and follicle-stimulating hormone (FSH) concentrations in 90 clinically healthy dromedary camels (Camelus dromedarius). Animals were grouped into three age categories (2–4, 5–10, and ≥11 years), with equal representation of males and females. The precise reproductive status of the female camels (e.g., estrous stage or pregnancy status) was not determined and should be considered when interp …

17.08.2026journal-article

International Journal of MS Care

Risks and Benefits of Disease-Modifying Therapies in People Aging With Multiple Sclerosis

John R. Corboy, Sarah A. Morrow, Patty Bobryk, Jeff Wilken, Jennifer S. Graves, Ruth Ann Marrie, Jacquelyn Bainbridge, Renee, Rachael Stacom, Mona D. Bostick, Maureen T. Choman, Frederick W. Foley, Yinan Zhang, Scott D. Newsome, Le H. Hua

Worldwide, the average age of people with multiple sclerosis (MS) has increased significantly over the past several decades. Findings from natural history studies reveal that the risk of new relapse and MRI activity diminishes with age. Available since 1993, the use of disease-modifying therapies (DMTs) for MS has expanded dramatically, with many patients using the drugs indefinitely. The participants of most phase 3 clinical trials that have resulted in regulatory approval of MS DMTs have been 55 years or younger …

17.08.2026journal-article

Edinost in dialog: Revija za ekumensko teologijo in medreligijski dialog

One Heart and One Soul under Trial. Barnabas, Ananias and Sapphira in Acts 4:32–5:11: Luke’s Portrait of the Restored People of God

Matjaž Celarc

The account of Ananias and Sapphira (Acts 5:1-11) remains one of the most contested passages in Acts. Scholarly discussion has frequently focused on questions of communal property, economic ethics, apostolic authority, divine judgment, or the historical plausibility of the couple’s deaths. While these issues are important, the narrative is often interpreted in relative isolation from its immediate literary context. This article argues that Acts 4:32–5:16 constitutes a coherent literary and theological unit. The sum …

17.08.2026journal-article

Journal of Alzheimer’s Disease

Relationship between body composition and mortality in older patients with mild cognitive impairment and Alzheimer's disease: NCGG-STORIES

Kazuaki Uchida, Taiki Sugimoto, Takeshi Nakagawa, Taiji Noguchi, Ayane Komatsu, Rei Ono, Yoko Yokoyama, Ayaka Onoyama, Takashi Sakurai, Tami Saito

Background Although a lower body mass index (BMI) has been identified as a prognostic risk factor among older adults with cognitive impairment, it remains unclear which body composition are associated with prognosis. Objective This study investigated the relationship between body composition and mortality in older adults with mild cognitive impairment (MCI) and Alzheimer's disease (AD). Methods This longitudinal study, using data from a memory clinic in Japan, included patients aged ≥65 years who were clinically di …

17.08.2026journal-article

FPOP Bulletin: Psychology of Older People

Experiences of using Dementia Care Mapping™ on a male acute older adult inpatient unit for over 65s

Devon Perfect

Dementia Care Mapping™ is an observational tool developed by the University of Bradford to help care staff understand the lived experiences of individuals living with dementia living from their own perspective. This is especially important when the individual displays behaviours that challenge care staff, as DCM™ can help identify experiences and environmental factors that may further contribute to, or help alleviate, the distress associated with this behaviour. While DCM™ is more commonly used in residential and n …

17.08.2026journal-article

Journal of Urban Health

Place-Based Structural Disadvantage, Lethal Police Violence, and Adverse Birth Outcomes Among Black Birthing People

Emma A. Blackson, Briana M. Williams, Jé Judson, Caryn Bell, Maeve E. Wallace

Abstract Structural racism and lethal police violence shape community environments, particularly in urban and urban-adjacent contexts, and may influence reproductive health. While disparities in birth outcomes among Black populations are well documented, fewer studies have examined how these structural and state-linked exposures jointly pattern risk for adverse birth outcomes. Using 2020 National Center for Health Statistics natality data and Mapping Police Violence data (2015–2019), we analyzed associations betwee …

17.08.2026journal-article

The Journal of Cardiovascular Aging

Circulating biomarkers for the diagnosis, risk stratification, and translational assessment of fulminant myocarditis

Jianpei Wen, Shenglan Yang, Chen Chen

Fulminant myocarditis (FM) is the most severe and urgent type of myocarditis, characterized by rapid hemodynamic deterioration, malignant arrhythmias, and frequent multiorgan dysfunction. In this case, timely diagnostic decisions are critical. Because endomyocardial biopsy or cardiac magnetic resonance is time-consuming and requires specialized equipment and expertise, plasma biomarkers play an important role between initial clinical suspicion and later pathological confirmation. This review summarizes plasma bioma …

17.08.2026journal-article

Autism in Adulthood

A Diagnosis Buried in the Closet: How Autistic People Learn of Their Autism Diagnoses

Dakyeom Lee, Insuk Ryu, Joonheon Kwon, wn-ho Yoon, Hee Jeong Yoo, So Yoon Kim

Background: Learning that one is autistic can be a pivotal turning point in self-understanding, but autistic people learn of this information under highly variable conditions. How these disclosure conditions shape autistic people’s experiences of learning and making sense of the diagnosis remains underexamined, particularly for those who received an autism diagnosis in childhood but learned about it later, and in non-Western contexts. Methods: We conducted semi-structured qualitative interviews with 22 formally dia …

17.08.2026journal-article

FPOP Bulletin: Psychology of Older People

The Confidence in Dementia (CODE) Scale: A review of its development and application

Ruth Elvish, John Keady

This review article outlines the development and properties of the Confidence in Dementia (CODE) scale, which was first published in 2014 in a study led by the first author of this review article. The validity and reliability of the CODE scale have been subjected to rigorous independent testing since its first publication, translated into several different languages, and used in dementia care settings and contexts outside of its original development in the general hospital setting. The CODE scale may be particularl …

17.08.2026journal-article

Journal of Indigenous Knowledge and Practice

Roots, Rituals, and Resistance: The Indigenous Knowledge Systems of the Tharu People in Nepal

Uddhav Sigdel, Man B. Sunuwar, Laxmi Adhikari, Tara B. Thapa

Indigenous knowledge systems (IKS) are epistemological traditions that have supported human communities over time which are dynamic, ecologically embedded, and socially reproduced. Although growing scientific and policy attention is being directed towards indigenous knowledge systems. In general, Tharu people continue to be underrepresented in mainstream scientific and development discourses, and in particular, ethnically and geographically marginal communities within South Asia have their traditional knowledge sys …

17.08.2026journal-article

Geriatrics

Beyond Chronological Age: Frailty, Vulnerability, and Invasive Decision-Making in Older Adults with Acute Coronary Syndromes

Lourdes Vicent, Rafael Salguero-Bodes, Pablo R. Alonso, Helena Alarcos, Elena Puerto García-Martín, Carlos Diaz-Arocutipa, Fernando Arribas Ynsaurriaga, Roberto Martín-Asenjo

Older adults represent a growing proportion of patients presenting with acute coronary syndromes (ACS), yet they remain a highly heterogeneous population in terms of biological reserve, comorbidity burden, functional status, cognitive performance, and recovery potential. Chronological age alone is an insufficient basis for invasive decision-making, as it may lead to both therapeutic nihilism and disproportionate treatment escalation. Frailty has emerged as a clinically meaningful construct that captures vulnerabili …

17.08.2026journal-article

Physiotherapy Research International

Acute Foot Warming Enhances Plantar Tactile Sensitivity With Limited Postural Control Effects in Obese Older Adults

Mathias Sosa Machado, Lissandra dos Santos Gonçalves, Amanda Carolina Paim Camponogara, Marieli Miranda Paz, Álvaro Sosa Machado, Felipe P. Carpes

ABSTRACT Background and Purpose Interventions to enhance tactile sensitivity, such as warming the feet, positively affect skin sensitivity with varying influence on postural control. Here, we hypothesize that foot warming may benefit tactile sensitivity and postural control in older adults, particularly those with obesity. Methods Fifty participants divided into 16 middle‐aged adults (14 women, mean ± standard deviation: age 40.29 ± 3.73 years, body mass index, BMI, 24.51 ± 1.70 kg/m 2 ), 17 non‐obese older adults …