Frag' FlorenceEvidenz. Klar. Anwendbar.
Uhr 7/8Sources Journal Tree
Easy Demo

Florence Themenbrowser · Therapie & Reha · Seite 49

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
20.08.2026journal-article

Frontiers in Cell and Developmental Biology

Context-dependent functions of the aryl hydrocarbon receptor in gastrointestinal cancers: from microenvironmental regulation to precision targeted therapy

Jiao Ma, Shenghao Li, Yining Qiao, Zihan Gao, Jinzhe Liu, Yanru Song, Yu Liu, Xiaohui Ji, Jianbo Li, Jie Zhang, Liang Chang, Bingjie Huo

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor with context-dependent roles in gastrointestinal (GI) tumor development. Depending on cellular context and microenvironment, AhR can preserve epithelial integrity, suppress inflammation, and inhibit tumor growth, but it can also promote immune evasion and metabolic reprogramming to drive tumor progression. Most existing reviews have focused on a single GI tumor type or functional dimension, and the concept of AhR as a context-dependent s …

20.08.2026journal-article

Journal of the American Heart Association

Assessing Brain Lesions and Predicting Functional Outcome in Patients With Anterior Circulation Stroke With Endovascular Therapy: Co‐ASPECTS

Jiaqi Luo, Xiaolin Zhao, Mengxuan Xiao, Guoshuai Yang, Pengxiang Li, Weihua Liu, Suyue Pan, Yidong Deng, Xianghong Liu, Kaibin Huang

Background This study aimed to develop and validate a practical and reliable tool for comprehensive assessment of brain lesions on immediate post‐endovascular therapy (EVT) noncontrast computed tomography (CT) and to predict 90‐day functional outcomes in patients with acute ischemic stroke. Methods We retrospectively reviewed consecutive patients with acute ischemic stroke undergoing EVT from 2 academic hospitals as the development cohort and used an independent national multicenter prospective cohort for external …

20.08.2026journal-article

Clinical Cancer Research

Long-term Follow-up of Third-generation Anti-CD30 CAR T-cell Therapy in Relapsed/Refractory CD30+ Lymphomas: A Single-Arm, Multicenter, Phase I/II Trial

Xiangmin Wang, Qing Zhang, Dongmei Yan, Yawen Wei, Hongzhi Geng, Kang Rong, Jiahui Sun, Xicheng Chen, Meina Zhang, Peiling Zhang, Yujie Li, Ruiyang Xie, Han Sun, Ziyuan Shen, Hongyuan Zhou, Tianci Li, Jiaoli Zhang, Yicheng Zhang, Tongcun Zhang, Linyan Xu, Ting Niu, Wenbin Qian, Qingyun Wu, Liang Huang, Caixia Li, Wei Sang

Abstract Purpose: This report presents long-term outcomes of third-generation anti-CD30 chimeric antigen receptor (CAR) T-cell therapy in patients with relapsed/refractory (r/r) CD30+ lymphoma. Patients and Methods: In this single-arm, multicenter, phase I/II trial, patients received a lymphodepletion regimen comprising fludarabine and cyclophosphamide, followed by infusion of anti-CD30 CAR T cells. Primary endpoints included safety and overall response rate (ORR), whereas secondary endpoints were progression-free …

20.08.2026journal-article

Revista ft

Método ONI® – Organização Neurointegrativa Neonatal: proposição de um modelo conceitual para o cuidado fisioterapêutico em neuroproteção para recém-nascidos internados em Unidade de Terapia Intensiva Neonatal.

Carina Perruso Ultra, Rogério Brito Ultra, Adriane Montardo de Carvalho, Lenice Michels

The survival of premature and critically ill newborns has increased significantly in recent decades due to advances in neonatal intensive care. However, early exposure to the Neonatal Intensive Care Unit (NICU) environment can interfere with central nervous system development, making the adoption of strategies focused on neuroprotection and developmental care essential. Although various interventions are widely described in the literature, there is a lack of a conceptual model that organizes—from the perspective of …

20.08.2026journal-article

Pharmacognosy Magazine

Terpenoids and Steroids from Marine Invertebrates: Emerging Anti-metastatic Agents in Cancer Therapy

Abdulmajeed M. Jali

Metastasis is the principal cause of cancer-related mortality, and existing therapeutic strategies are ineffective in preventing tumour dissemination and metastatic colonisation. Therefore, it is essential to identify drugs that target the molecular processes regulating metastatic progression. Marine invertebrates serve as a remarkably rich source of structurally diverse secondary metabolites, including terpenoids and steroids, many of which exhibit distinctive biological activities unseen in terrestrial natural pr …

20.08.2026journal-article

Journal of Robotics and Mechatronics

Error Compensation Strategies for Lower-Limb Rehabilitation Robots: A Staged Approach with MLP and Transformer Models

Aihui Wang, Rui Teng, Jinkang Dong, Xuebin Yue, Xiang Zhang

Lower-limb rehabilitation robots are valuable for gait training, but accurate joint motor angle tracking remains challenging due to various motion-related disturbances. This paper presents a staged joint-compensation strategy to improve control accuracy. The gait control process is partitioned into initiation, cyclic, and termination phases. A multilayer perceptron is employed during initiation and termination to predict and compensate for short-term aperiodic errors, while a Transformer-based sequence model combin …

20.08.2026journal-article

Annals of General Psychiatry

Validating objective and scalable speech markers of depression across two independent psychiatric cohorts

Felix Menne, Felix Dörr, Johannes Tröger, Alexandra König, Julia Schräder, Diana Immel, René Hurlemann, Simon Barton, Lisa Wagels

Abstract Background Using speech as objective markers for major depressive disorder (MDD) has shown promise, yet their generalizability across clinical settings remains largely unvalidated. Objective This study aimed to validate previously identified speech markers of depressive symptoms in an independent clinical cohort, thereby assessing their reproducibility and robustness for cross-site application. Methods Speech data from two independent psychiatric cohorts (RWTH Aachen and University of Oldenburg, Germany) w …

20.08.2026journal-article

Journal of Cardiovascular Pharmacology

Triple Antithrombotic Therapy for the Prevention of Left Ventricular Thrombus Following Anterior ST-Elevation Myocardial Infarction: A Systematic Review and Meta-Analysis

Anastasios Apostolos, Vasileios Panoulas

Left ventricular thrombus (LVT) is a serious complication of anterior ST-elevation myocardial infarction (STEMI). Despite guideline endorsement of prophylactic anticoagulation in selected high-risk patients, the supporting evidence remains of low certainty. Aim of our systematic review and meta-analysis is to evaluate the efficacy and safety of triple antithrombotic treatment (TAT) versus dual antiplatelet treatment (DAPT) alone for LVT prevention in patients with anterior STEMI treated with primary percutaneous co …

20.08.2026journal-article

American Journal of Speech-Language Pathology

Upward Effortful Pitch Glide as a Predictor of Pharyngeal Constriction in Individuals With Upper Versus Lower Motor Neuron Lesions

Scott King, Elizabeth Lanza, Benjamin Schiedermayer, Zhining Ou, Julie Barkmeier-Kraemer

Purpose: This study tested the validity of using nasoendoscopy ratings of volitional maximum pharyngeal constriction (PCmax) during nasoendoscopy recordings of effortful upward pitch glide to predict pharyngeal area at maximum constriction (PAM) during swallowing recordings (VFSSs) in individuals with upper motor neuron (UMN) versus lower motor neuron (LMN) lesions. Method: Retrospective analysis of electronic medical records identified individuals with UMN or LMN lesions who underwent both VFSS and nasoendoscopy w …

20.08.2026journal-article

Child Language Teaching and Therapy

Unpacking Irish primary teachers’ perceptions of speech and language therapists’ scope of practice in literacy assessment and intervention

Paula Lehane, Christina Hannify, Sylwia Kazmierczak-Murray

Literacy success is strongly linked to language competence, yet many primary teachers lack the linguistic knowledge necessary for effective literacy instruction. Interprofessional collaboration with speech and language therapists offers a promising model to address this gap, particularly as literacy increasingly falls within speech and language therapists’ scope of practice. However, teachers’ readiness for, and perspectives on, such partnerships vary internationally, and Irish teachers’ views remain largely unexpl …

20.08.2026journal-article

OTJR: Occupational Therapy Journal of Research

Kangaroo Mother Care: A Bibliometric Scoping Analysis of Global Literature and Implications for Occupational Therapy

Alaina Nickerl, Dara Fuller, Selena Williams, Alexandra Shandalov, Kinsuk Maitra

Kangaroo mother care (KMC) has gained increasing attention for its role in improving the health and survival of preterm infants in the neonatal intensive care unit (NICU). We performed a bibliometric analysis of KMC literature to understand whether the topic has been generating interest in the global research community. We used VOSviewer software for a bibliometric analysis of KMC literature (1993–2024) using the Web of Science database. The emerged research direction created a tightly linked word cluster around th …

20.08.2026journal-article

Journal of Back and Musculoskeletal Rehabilitation

Validity of a smartphone-based spinal assessment tool (TricuroGo) against idiag M360 and selective functional movement assessment (SFMA) in evaluating sagittal posture, mobility, and stability

Lea Overmann, Robert Schleip, Luisa Barr, Christoph Egner, Werner Klingler, Marcus Müller, Andreas Brandl

Background Accurate sagittal spinal assessment is crucial in physiotherapy, but current methods strike a balance between precision and practicality. Radiographic measures are valid but impractical for repeated use, whereas observational tools, such as the Selective Functional Movement Assessment (SFMA), are subjective. Device-based approaches, such as Idiag M360, are validated but costly. Smartphone-based systems, such as TricuroGo, offer accessible alternatives, although their validity remains underexplored. Objec …

20.08.2026journal-article

Work, Employment and Society

‘Living Props’: Background Actors and the Production of ‘Occupational Irrelevance’ within Film and Television Work

Saara Liinamaa, Michael Follert

This article treats background acting as an archetypal case for theorising sociologically the work and workers that exist in the backdrop of a workplace. Turning to the sociology of attention and its conceptualisation of the background of everyday life, it draws on Zerubavel’s ‘social structure of irrelevance’ to understand background acting as an occupation. Based on in-depth interviews with unionised and non-unionised background actors working in the Canadian screen industry, three backgrounding practices are ide …

20.08.2026journal-article

Frontiers in Immunology

Molecular basis of post-translational neoantigen generation in rheumatoid arthritis: breaking immunological tolerance and implications for targeted therapy

Alba Pérez Linaza, Sussel Picallo Díaz, Isabel Serrano García, Wenjie Yi, Álvaro Guerrero Lores, Juan Manuel Aragón González, Francisco Garcia-Cozar, Cecilia Fernandez-Ponce, Ricardo Fernandez-Cisnal

Autoimmune diseases are characterized by a loss of immune system tolerance to self-antigens, which can trigger an immune response capable of affecting various organs and tissues. An increase in the prevalence of these diseases has been reported in recent years. Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disorder characterized by persistent synovial inflammation. While it predominantly targets small and medium-sized joints, its pathogenesis frequently extends to diverse extra-articular manifestation …

20.08.2026journal-article

Multisensory Research

Assessing Visual Speech Communication Abilities: Cross-Situational Consistency in Lipreadability

Joel Myerson, Brent P. Spehar, Michael J. Strube, Sandra Hale, Nancy Tye-Murray, Mitchell S. Sommers, Jonathan E. Peelle

Abstract Speech perception during face-to-face conversations is perhaps the most functionally significant aspect of multisensory processing in people’s everyday lives. Although they may not be aware of it, people use lipreading to both supplement auditory processing under poor listening conditions and compensate for age-related declines. Thus, understanding the sender’s role in communication is as important as understanding the receiver’s role, and in both cases, a fundamental question concerns whether individual d …

20.08.2026journal-article

Annals of Clinical Hypertension

Phenotype-Guided Hypertension Management in the Era of Cardiovascular–Kidney–Metabolic Syndrome: Integrating the CKM and MACARENHA Models for Personalized Dual and Triple Antihypertensive Therapy

Martin Rosas-Peralta, Luis Alcocer, Héctor Galván-Oseguera, Ernesto Cardona-Muñoz, Humberto Álvarez-López, Adolfo Chávez-Mendoza, J Manuel Enciso-Muñoz, Enrique Díaz-Díaz, Silvia Palomo-Piñón

Background: Hypertension remains the leading modifiable contributor to cardiovascular morbidity and mortality worldwide despite the availability of effective antihypertensive therapies. One of the principal limitations of contemporary management is that treatment strategies continue to focus predominantly on blood pressure values rather than on the biological complexity of the patient. Increasing evidence demonstrates that hypertension rarely exists as an isolated disease; instead, it develops within a complex netw …

20.08.2026journal-article

Journal of Back and Musculoskeletal Rehabilitation

Comparison of cardiovascular diseases risk awareness, physical activity, nutritional habits and cardiovascular risks in female patients with rheumatoid arthritis and knee osteoarthritis: A cross-sectional study

Selda Çiftci İnceoğlu, Aylin Ayyıldız, Meryem Aşık, Deniz Yoldan, Alperen İnceoğlu, Banu Kuran

Background and Objective Both rheumatoid arthritis (RA) and knee osteoarthritis (KOA) are associated with increased cardiovascular diseases (CVDs) risk. Although lifestyle factors have been studied in these patients, data directly comparing CVDs risk awareness between RA and KOA remain limited. Therefore, this study aimed to compare CVDs awareness, physical activity, nutritional habits, and cardiovascular risk factors between female patients with RA and KOA. Methods Female patients aged ≥40 years with RA, diagnosed …

20.08.2026journal-article

BMC Complementary Medicine and Therapies

Use of massage therapy for non-painful health conditions: an evidence map of systematic reviews

Selene S. Mak, Jennifer E. Allen, Meron M. Begashaw, Jessica M. Beroes-Severin, Isomi M. Miake-Lye, Paul G. Shekelle

Abstract Background There is high- or moderate-certainty evidence that massage therapy is beneficial for certain painful conditions. Massage therapy has also been evaluated for a range of non-painful health conditions, but the extent and certainty of this evidence are less well characterized. We mapped the systematic reviews, conclusions, and certainty (quality or strength) of evidence for outcomes of massage therapy for non-painful health conditions. Methods Computerized search of PubMed, AMED, CINAHL, Cochrane Da …

20.08.2026journal-article

Journal of Midwifery & Women's Health

Women's Experiences of Community‐Based Midwifery Care Provided by Independent Midwives in Turkey: A Qualitative Study Based on the World Health Organization Positive Childbirth Experience Framework

Betül Uncu, Feyza Aktaş Reyhan, Elif Selimoğlu

Introduction Midwife‐led birth models are gaining increasing acceptance because of their potential to promote respectful, woman‐centered, and positive birth experiences. However, evidence regarding women's lived experiences of midwife‐led births in Turkey is limited. This study aimed to investigate women's experiences, perceptions, and thoughts regarding midwife‐led births in Turkey within the World Health Organization (WHO) Positive Birth Experience Framework. Methods A qualitative descriptive design was employed. …

20.08.2026journal-article

Frontiers in Medicine

Participatory co-design of pediatric rehabilitation technologies: a practice-based perspective

Arie Melamed Yekel, Naomi Gefen, Patrice L. Weiss

Digital rehabilitation technologies are rapidly expanding across pediatric healthcare, yet many innovations fail to achieve sustained clinical adoption. In pediatric rehabilitation, this translation gap is amplified by heterogeneity in diagnoses and developmental stages, the need for family-centered care, and the practical constraints of clinical workflows. In this Perspective article, we argue that participatory co-design, an iterative process that actively involves clinicians, children, caregivers, and developers …

20.08.2026journal-article

Neurological Sciences

Optimal physiotherapy management strategies for cervical dystonia: an international Delphi study

Melani J Boyce, Camila Quel de Oliveira, Alana B. McCambridge, Colleen G. Canning, Peter Stubbs, Arianne P. Verhagen

Abstract Background Isolated cervical dystonia is a rare, lifelong, focal, idiopathic dystonia causing uncontrollable spasms in the neck. In conjunction with medical management, physiotherapy can improve pain and quality of life, however there are no evidence-based guidelines indicating optimal physiotherapy goal setting, assessments and treatments. Purpose To determine international consensus among physiotherapists who regularly treat people with cervical dystonia on optimal physiotherapy management. Methods A Del …

20.08.2026journal-article

Manager Zdravookhranenia

Clinical and organizational issues in the early diagnosis of occupational sensorineural hearing loss.

D. I. Shubin, D. O. Roshchin

Background. Occupational sensorineural hearing loss (OSNHL) remains one of the leading nosological entities in the structure of occupational morbidity in the Russian Federation, demonstrating an upward trend. Despite the existence of approved federal clinical guidelines regulating the diagnosis and patient routing, their systematic non-compliance by medical organizations during periodic medical examinations (PME) is frequently observed in real clinical practice, which significantly reduces the effectiveness of earl …

20.08.2026journal-article

Neurorehabilitation and Neural Repair

Analysis of Home-Based Rehabilitation Robotics: Lessons Learned from Nationwide Direct-to-Consumer Deployment

Russell Jeter, Steven L. Wolf, Stephen N. Housley

Introduction: Millions of stroke survivors in the US have sensory-motor impairments that significantly impact quality of life and place a long-term burden on families, communities, and the healthcare system. Neurorehabilitation aims to improve function, typically through repetitive practice of movements and task-related activities where doses are regularly titrated by skilled clinicians. Unfortunately, these highly intensive, skilled interventions are challenging to implement at the scale needed to serve the needs …