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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

International Journal of Clinical and Experimental Medical Sciences

Biofilm Formation and Detection of the icaA Gene in Staphylococcus Aureus Isolates from Ocular Infections

Karar Abdulkhuder, Mahmood Awad

Background: Staphylococcus aureus is a major opportunistic pathogen implicated in various infections, including ocular infections. One of its key virulence factors is the ability to form biofilms, which are structured bacterial communities embedded in a self-produced extracellular matrix. Biofilm formation enhances bacterial survival under adverse conditions, including antibiotic exposure and host immune defenses, thereby contributing to chronic and recurrent infections. Aim: This study aimed to evaluate the biofil …

27.08.2026journal-article

PLOS One

Mental health and family functioning among physically healthy Syrian refugees resettled in Ontario, Canada post 2015: A cross-sectional study

Bahia Abdallah, Abir Abdel Rahman, Safoura Zangiabadi, Hala Tamim

Refugees are often exposed to traumatic experiences before, during, and after migration, placing them at increased risk of mental health problems, including depression, anxiety, and post-traumatic stress disorder (PTSD). This cross-sectional study investigates the relationship between mental health and family functioning among Syrian refugees who resettled in Ontario, Canada, post-2015. The final sample included 398 parents residing in Ontario who reported good to excellent physical health. Validated tools, includi …

27.08.2026journal-article

Development Service Industry Management

УПРАВЛІННЯ ПРОЄКТАМИ ВПРОВАДЖЕННЯ CRM-СИСТЕМ ТА ТЕХНОЛОГІЙ ШТУЧНОГО ІНТЕЛЕКТУ У СИСТЕМУ АНТИКРИЗОВОГО УПРАВЛІННЯ КЛІЄНТСЬКИМ КАПІТАЛОМ ПІДПРИЄМСТВА

Ніла ТЮРІНА, Тетяна НАЗАРЧУК

The article explores the theoretical and applied foundations of project management regarding the implementation of CRM systems and artificial intelligence (AI) technologies within the enterprise's crisis management system for customer capital. The relevance of the study is driven by the imperative to optimize customer interactions amid digital transformation and high turbulence in the business environment. The study aims to substantiate theoretical and methodological provisions and to develop a conceptual framework …

27.08.2026journal-article

Clinical and Translational Medicine

NSUN4‐dependent m5C modification facilitates mitochondrial fission to accelerate diabetic nephropathy process via regulating SMURF1/CAMK1 axis

Danyi Yang, Yinyin Chen, Hao Li, Guoyong Liu, Yang Gao, Liyu He

Abstract Background NOP2/Sun RNA methyltransferase family member 4 (NSUN4)‐mediated 5‐methylcytosine (m5C) modification has been implicated in diabetes‐related diseases. However, its role and molecular mechanism in diabetic nephropathy (DN) remain unclear. Methods DN mouse model was constructed by injecting with streptozotocin (STZ). High glucose (HG)‐induced HK‐2 cells were used to establish a cellular model of DN. The levels of NSUN4, SMAD ubiquitination regulatory factor 1 (SMURF1), calcium/calmodulin‐dependent …

27.08.2026journal-article

IoT

Intelligent Transportation Systems: A Review of Integration of Digital Twin and Machine Learning Control

Thit Tun, Hakilo Sabit

This paper presents a comprehensive review of the integration of Intelligent Transportation Systems (ITS) and Digital Twin (DT) technologies for intelligent traffic management. It examines the role of key enabling technologies, including the Internet of Things (IoT), machine learning (ML), deep learning (DL), reinforcement learning (RL), Graph Neural Networks (GNNs), vehicle-to-everything (V2X) communication, and edge computing. These technologies support real-time traffic monitoring, traffic prediction, and adapti …

27.08.2026journal-article

Journal of Learning Analytics

Driving Personalised and Adaptive Professional Competencies with Generative AI and Learning Analytics: Pioneering Applications in Health Professions Education

Bernard Bucalon, Lixiang Yu, Tim Shaw, Dragan Gasevic, Judy Kay, Anna Janssen

Professional learning environments offer a unique opportunity for exploring professional competencies due the use of workplace data which captures important aspects of professional performance. These data are different from those used in formal learning analytics contexts, as they are not collected by systems designed to understand learning. Instead, workplace data represents the digital fingerprint professionals leave behind when interacting with technologies to do their jobs. Harnessing these data to support work …

27.08.2026journal-article

Financial Analytics Science and Experience

Analysis of clusters of Russian companies by level of development of digital transformation

Elena A. FEDOROVA, Bela S. BATAEVA, Anna D. GRACHEVA

Subject. Digital transformation of Russian public companies as a multilevel and heterogeneous process, including the introduction of artificial intelligence, big data, cloud computing, blockchain and applied digital technologies, as well as its reflection in corporate reporting. Objectives. Identification of empirical types (clusters) of digital transformation of Russian public companies based on a text analysis of annual reports for 2014–2024. Methods. The method of text analysis is used to measure the intensity o …

27.08.2026journal-article

Brazilian Journal of Implantology and Health Sciences

Desafio Diagnóstico e Conduta Cirúrgica em Lesão de Assoalho Bucal: Relato de Caso com Divergência Clínico-Patológica

Davi Barbosa Portela, Helóisa De Colo, Maria Clara Fernandes, Cristiane Elisa Ribas, Alissa Dos Santos Coelho, Eugenio Esteves Costa

Introdução: A rânula é uma lesão cística de extravasamento ou retenção de muco que acomete o assoalho bucal, intimamente relacionada à glândula sublingual. Seu diagnóstico é primariamente clínico, fundamentado em características como coloração azulada, flutuação e localização anatômica. O tratamento varia desde a micromarsupialização até a exérese da glândula sublingual. Objetivos: Relatar um caso clínico de lesão em assoalho bucal com hipótese diagnóstica de rânula, submetida à marsupialização com dreno, destacand …

27.08.2026journal-article

CONSTITUTIONAL AND MUNICIPAL LAW

Constitutional Law of Russia as a Legal Matrix of Digital Transformation: Contemporary Challenges and Strategic Guidelines

Anastasia I. Obraztsova

The article examines the transformation of constitutional law functions in the context of digitalization, analyzing the concept of constitutional law as a “legal matrix” of digital transformation. The constitutional amendments of 2020, the legal positions of the Constitutional Court of the Russian Federation on the limits of artificial intelligence use, and the problems of personal data protection are considered. The author substantiates the need to develop a Concept of Constitutional and Legal Support for Digital …

27.08.2026journal-article

Clinical Kidney Journal

Managing hyponatremia: fast or slow? why, when, how, and controversies

Kamel S Kamel, Ziv Harel, Martin Schreiber

Abstract Hyponatremia is the most common electrolyte disorder encountered in clinical practice. Its management is challenging because treatment must balance the risk of cerebral edema in acute hyponatremia against the risk of osmotic demyelination syndrome (ODS) from overly rapid correction of chronic hyponatremia. Recent observational studies have questioned current correction limits, prompting renewed debate regarding optimal management. This narrative review presents a physiology-based approach to the evaluation …

27.08.2026journal-article

Laser & Photonics Reviews

Synaptic Transistors Integrated With Triboelectric Nanogenerators for Artificial Perception and Neuromorphic Computing

Yaqian Liu, Menghua Lang, Manyu Zhang, Yihang Xu, Xiumei Wang, Zhu Liu, Leman Kuang, Linfeng Sun, Huipeng Chen, Liying Jiang, Hui Jing

ABSTRACT Bioinspired artificial perception systems (APS) are a crucial technical approach for future embodied intelligence, while mimicking perception with low power consumption, high integration, and matched transmission speed is the key element to achieve real‐time high‐efficiency APS. Recently, tribo‐transistors with a simple architecture have provided an innovative solution by directly converting mechanical stimuli into electrical signals, eliminating the need for external tactile sensors and thus improving int …

27.08.2026journal-article

Health Research Journal of Indonesia

HbA1c Levels and Ureum Creatinine Levels Among T2DM Patients in Indonesia: A Systematic Review

Satria Akbar Putra Asmara, Kahaya Ainin Asya, Alissa Anna Safira, Cinta Putri Aulia Nugroho, Muhammad Rio Al Faridzky

Pendahuluan: Diabetes mellitus tipe 2 (DMT2) merupakan penyebab utama penyakit ginjal kronis yang diakibatkan oleh hiperglikemia kronis, yang dapat menyebabkan kerusakan glomerulus. Tinjauan sistematis ini bertujuan untuk menganalisis hubungan antara kadar HbA1c dengan kadar ureum dan kreatinin pada pasien DMT2 di Indonesia. Metode: Tinjauan sistematis dilakukan sesuai dengan pedoman PRISMA 2020. Pencarian literatur dilakukan menggunakan Google Scholar, Garuda, PubMed, EBSCO, dan Scopus. Risiko bias dievaluasi meng …

27.08.2026journal-article

Aposta: Revista de Ciencias Sociales

Urgência e emergência: uma análise das plataformas SUS Digital na interoperabilidade e na coordenação dos fluxos assistenciais entre o SAMU, as UPA, as centrais de regulação e os hospitais da rede de atenção às urgências

Valderidson Macedo Ferreira Junior, Mauro de Deus Passos, Moacir Tavares Martins Filho, Nair Santos Souza, Andressa Silva dos Santos, Lara Misztela dos Santos, Everton da Costa Ramalho, Sayonara Brandão de Lima, Nikolas Alvares Fernandes, Stella Louise Almqvist, Débora Denise Silva de Jesus, Viviane Peixoto de Paula, Andrea Cristina Rocha, Laura de Mello Medeiros, Daniel Cardoso Madeira, Isaias Laune Madeira, Júnior Girardi, Kacilda Costa de Oliveira Sampaio, Rosângela Aguiar Vilanova

A atenção às urgências e emergências exige comunicação rápida entre os diferentes serviços, acesso integrado às informações clínicas e definição precisa dos encaminhamentos realizados ao longo da rede assistencial. Nesse contexto, as Plataformas SUS Digital podem contribuir para reduzir a fragmentação do atendimento e favorecer a continuidade do cuidado entre os serviços pré-hospitalares, as unidades de pronto atendimento, a regulação e os hospitais. O artigo tem como objeto de pesquisa a atuação das Plataformas SU …

27.08.2026journal-article

Journal of Clinical Oncology

Refined Continuous Risk Index for Accurately Predicting Outcomes of Patients With Chronic Lymphocytic Leukemia After Limited-Duration Therapy

Othman Al-Sawaf, Can Zhang, Mohammad S. Esfahani, Chih Long Liu, Sandra Robrecht, Eugen Tausch, Anke Schilhabel, Matthias Ritgen, Christof Schneider, Martin Peifer, Moritz Fürstenau, Carsten Utoft Niemann, Arnon P. Kater, John F. Seymour, Brenda Chyla, Yanwen Jiang, Barbara Eichhorst, Stephan Stilgenbauer, Michael Hallek, Ash A. Alizadeh, David M. Kurtz, Kirsten Fischer

PURPOSE Measurable residual disease (MRD) status after limited-duration treatment for chronic lymphocytic leukemia (CLL) strongly predicts survival times and is considered a surrogate end point. However, most prognostic indices, including the International Prognostic Index (CLL-IPI), rely solely on pretreatment features. To incorporate dynamic MRD data in prognostic models, the continuous individualized risk index (CIRI) was proposed in 2019. Since developed in the context of chemoimmunotherapy, we here propose a r …

27.08.2026journal-article

Asia-Pacific Journal of Clinical Oncology

Advancing Homologous Recombination Repair Mutation Testing in Prostate Cancer in Australia: Shifting the Focus to Hormone Sensitive Prostate Cancer

Arun A. Azad, Declan G. Murphy, Edmond M. Kwan, Anthony M. Joshua

ABSTRACT Homologous recombination repair (HRR) gene alterations are key drivers of disease in prostate cancer. This has led to great interest in HRR targeted therapies, particularly polyadenosine diphosphate‐ribose inhibitors (PARPi), in the treatment of metastatic castrate resistant prostate cancer (mCRPC). HRR alterations are typically early events in prostate cancer tumorigenesis. As a result, clinical trials are investigating the efficacy of PARPi therapy in metastatic hormone sensitive prostate cancer (mHSPC). …

27.08.2026journal-article

PLOS Digital Health

Bridging the health literacy gap: Women and community stakeholders’ perspectives on maternal and child health communication in peri-urban Karachi, Pakistan

Sameeta Kumari, Ayesha Khalid, Hajra Malik, Mahim Maher, Muhammad Imran Nisar, Fyezah Jehan, Zahra Hoodbhoy

Health literacy significantly influences health outcomes, particularly in Low-and Middle-Income Countries. Communication of maternal and child heath messages occurs via text messages, phone calls, television, newspaper articles, and home visits. An exploratory qualitative study was conducted in four peri-urban sites of Bin Qasim Town, Karachi to explore the perspectives of women and community stakeholders on effective health messaging strategies in peri-urban Karachi, Pakistan. Seven focus group discussions (FGDs) …

27.08.2026journal-article

Herald of Khmelnytskyi National University. Economic sciences

СУЧАСНІ ПІДХОДИ ТА ІНСТРУМЕНТИ МАРКЕТИНГОВОЇ ДІЯЛЬНОСТІ ПІДПРИЄМСТВ У ЦИФРОВОМУ СЕРЕДОВИЩІ

Олена ІВАНЧЕНКОВА

The article examines modern approaches and tools for enterprises' marketing activities in the digital environment, taking into account the dynamics of Internet technology development and the transformation of consumer behavior. The purpose of the study is to substantiate the conceptual foundations of the formation of an effective marketing policy of an enterprise in the digital economy and to systematize the digital marketing toolkit according to the stages of the sales funnel. The impact of digital technologies on …

27.08.2026journal-article

Karya Journal of Health Science

EARLY ERGONOMIC STRESS IN DENTAL EDUCATION: CHANGES IN PRESSURE PAIN THRESHOLDS, BODY AWARENESS AND MUSCULOSKELETAL DISCOMFORT AMONG PRECLINICAL DENTAL STUDENTS

Fatmagül Varol, Nesime Ayşenur Gülaydın, Sevde Koçyiğit, Pınar Baştürk Merç

Objective: Dentistry is widely recognized as an ergonomically challenging profession, with work-related musculoskeletal disorders (WMSDs) often developing early during undergraduate education. While physical workload is heavily studied, how preclinical education affects body awareness and pain sensitivity remains unexamined. This prospective observational study aimed to investigate concurrent changes in self-reported musculoskeletal discomfort, subjective body awareness, and objective pressure pain thresholds (PPT) …

27.08.2026journal-article

Eikasía Revista de Filosofía

El mito de lo mental

Jethro Masís

En sus dos partes, este estudio pretende reconstruir con cierto detalle el fiasco del proyecto de investigación de la Inteligencia Artificial y las consecuencias de la crítica devastadora de ese proyecto llevada a cabo por Hubert Dreyfus en su magnum opus What Computers Can’t Do (1972, 1979, 1992). Parte de estas consecuencias, es la emergencia de un grupo de investigadores en este campo especializado que se han llamado a sí mismos ‘heideggerianos’. Esta autodefinición será criticada en la segunda parte de este est …

27.08.2026journal-article

IIARD International Journal of Banking and Finance Research

Analysis of the Effect of Digital Transformation on Operational Performance of Deposit Money Banks in Nigeria

Andrew E.O. ERHIJAKPOR, PhD, FCA

The study examined the effect of digital transformation on operational performance of deposit money banks in Nigeria for the duration of 2001-2023 (23years). This was done in respect of measures of digital transformation, namely; Automated Teller Machine (ATM), Point of Sale (POS), Internet Banking (INTB) and Mobile Banking (MOB) and how it affects operational performance proxied with Efficiency Ratio (EFFR). The method of data collection used in this study was the secondary source of data (time series data), from …

27.08.2026journal-article

Procedia of Social Sciences and Humanities

AI-Driven Human Capital: BJB University’s Human Resources Transformation and Adaptation Strategies in the Digital Age

Rendy Adi Saputra, M. Hilmi Fajar, Ariel Yussi Muhammad, Syahrizal Pahlevi Utomo, Ika Oktaviyanti

General Background: Rapid advances in artificial intelligence and digital transformation have fundamentally changed workforce needs in the banking sector. Specific Background: Bank BJB examines employees' digital competency readiness and adaptation challenges to respond to technological developments through BJB University. Knowledge Gap: Existing literature largely focuses on technology performance rather than qualitative insights into employee adaptation and human resource transformation strategies within regional …

27.08.2026journal-article

Frontiers in Surgery

Laryngeal transplantation: from experimental feasibility to multidisciplinary clinical reality

Lu Zeng, Longhao Wang

Laryngeal transplantation represents one of the most complex forms of vascularized composite allotransplantation (VCA), aiming to restore respiration, phonation, and swallowing in patients with irreversible laryngeal dysfunction. Over the past decades, systematic preclinical research—including refinement of large-animal and rodent models, organ preservation optimization, and elucidation of immunological mechanisms—has laid the scientific foundation for clinical translation. Advances in static cold storage, emerging …

27.08.2026journal-article

Clinical Science

Maternal gut microbiota–psychotropic drug interactions and their impact on offspring neurodevelopment

Ashlee M. Craig, Kelly J. Clemens, Sarah-Jane Leigh

Abstract Pregnancy is associated with a unique and dynamic gut microbiota profile that supports fetal growth and neurodevelopment. Psychotropic drug–gut microbiota interactions are documented in the general population, yet less well described in pregnant women. Research has independently linked both perinatal psychotropic exposure and alterations to the maternal gut microbiome with potential changes to offspring neurodevelopment; therefore, it is plausible that similar interactions occur during pregnancy where they …

27.08.2026journal-article

Earth Surface Processes and Landforms

UAV‐Based Evaluation of National and Global Digital Elevation Models for Chronic Landslides in the Indian Himalayas

Ashok Anand, Indrakant Behera, Sahil Kundal, Alok Bhardwaj

ABSTRACT This study evaluates one national Digital Elevation Model (DEM) (CARTOSAT) and eight global DEMs (ALOS12.5, AW3D30, ASTER, COPDEM, FABDEM, GEDTM, NASADEM and SRTM) to represent the topography of 10 chronic landslides in the Garhwal Indian Himalayas, using high‐resolution Uncrewed Aerial Vehicle (UAV)‐derived DEMs as the reference. The majority of the chronic landslides considered in the study were activated/reactivated after the 2013 Kedarnath disaster in the Upper Ganga Catchment. Elevation, slope, aspect …