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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
16.08.2026journal-article

Journal of Clinical Medicine

Effects of Physical Exercise, Cognitive Stimulation, and Their Combination on Mobility, Cognitive Function, and Psychosocial Well-Being in Older Adults Residing in Long-Term Care: Protocol for a Randomised Controlled Trial

Nuno Carvalho, Rocío Llamas-Ramos, Inés Llamas-Ramos

Background/Objectives: Older adults residing in long-term care frequently experience multimorbidity, low habitual activity, mobility decline, executive dysfunction, and reduced quality of life. Evidence separating the effects of exercise, cognitive stimulation, and their combination remains limited. The primary objective of this trial is to determine whether a 12-week combined physical exercise plus cognitive stimulation programme improves executive function, functional mobility, and health-related quality of life …

16.08.2026journal-article

Psychogeriatrics

Efficacy and Safety of Electroconvulsive Therapy for Dementia With Lewy Bodies, Its Prodromal Phase, and Parkinson's Disease Dementia: Eight Cases Encountered at Our Institution

Takahide Fukatsu, Kouhei Fujita, Taro Yoshida, Mihoko Kawai, Jun Miyata

ABSTRACT Purpose This study aimed to assess the efficacy and safety of electroconvulsive therapy (ECT) for treating psychiatric symptoms and parkinsonism in patients affected by dementia with Lewy bodies (DLB), its prodromal phase, and Parkinson's disease dementia (PDD). Methods We retrospectively reviewed eight patients (four males, four females; mean age 71.5 ± 8.9 years) diagnosed with probable DLB or its prodromal phase, based on diagnostic criteria, who underwent ECT between January 2020 and December 2025. The …

16.08.2026journal-article

Materials

Pre-Deformation-Assisted Retrogression and Re-Aging Treatment for Achieving Strength–Corrosion Synergy in 2195 Al–Cu–Li Alloy: Insights into Cu Redistribution and Grain Boundary Evolution

Boyuan Zhou, Sheng Li, Shaoxuan Wu, Yao Li, Zhe Liu, Hongqun Tang, Wenbo Liu

Al–Cu–Li alloys face an intrinsic trade-off between precipitation strengthening and intergranular corrosion susceptibility. This trade-off restricts the simultaneous improvement of their strength and corrosion resistance. In this work, a pre-deformation-assisted retrogression and re-aging (RRA) strategy was developed to regulate Cu redistribution and balance the mechanical and corrosion properties of 2195 Al–Cu–Li alloy. The results show that short-time retrogression maintains effective strengthening while limiting …

16.08.2026journal-article

City, Territory and Architecture

Walkability and well-being among older adults: a perception-driven structural model for age-friendly urban planning in India

Akshatha Rao, Nandineni Rama Devi

Abstract The rapid growth of the older adult population (aged 60 years and above) underscores the urgent need for walkable urban environments that support their mobility, independence, and well-being. Although walkability is known to influence physical activity, social participation, and quality of life, empirical evidence explaining how perception-based dimensions of the built environment shape these outcomes remains limited, particularly in non-Western and developing country contexts. This study develops and vali …

16.08.2026journal-article

Journal of Geriatric Psychiatry and Neurology

Current Practice and Long-Term Developments in Multidisciplinary Dutch Memory Clinics

Stephan Duijkers, Daphne B. G. Ter Huurne, Marco Blom, Hanna E. Bodde, Jolanda H. M. Dobbe, Wiesje Van der Flier, Willemijn J. Jansen, Marcel Olde Rikkert, Janne M. Papma, Frans R. J. Verhey, Inez H. G. B. Ramakers

Objectives Memory Clinics (MCs) have a central role in multidisciplinary diagnostics and care of cognitive disorders and dementia. This study describes current clinical practice and developments of Dutch MCs since their start in 1986. Methods A survey was sent to all Dutch hospital-based MCs in 1998, 2004, 2009, 2017 and 2023. Topics included: organization, patient characteristics, scales and questionnaires, neuropsychological assessment, additional assessments, novel biomarkers, disclosure of diagnosis and treatme …

16.08.2026journal-article

Journal for Technology and Science

STUDY OF MINERAL LEVELS OF INFECTED PEOPLE WITH H. PYLORI

Asraa Nadhum Abd-Alsatar, Baraa Jalil Saeed, Zainab Falih Dakhil, Khairunnuur Fairuz Azman

Objective: Results from earlier research on the relationship between Helicobacter pylori (H. pylori), as well as osteoporosis. A few studies have examined H's effects. The current study aims to detect the effects of H. pylori on patients' mineral levels, particularly copper. Blood levels of copper, zinc, calcium, and magnesium are affected by pylori infection. Methods: The blood samples were collected using sterile containers. A H. pylori diagnosis was performed using a stool culture, and blood magnesium and calciu …

16.08.2026journal-article

Musculoskeletal Care

A Qualitative Exploration of the Multidimensional Influences on Physical Activity Among People With Arthritis

Justin Webb, Heather Allison

ABSTRACT Objective To explore the individual, interpersonal, community, organisational, and policy‐level factors that influence physical activity among people with arthritis in England, using the Social Ecological Model as the analytical framework. Study Design Qualitative research. Methods Semi‐structured interviews were conducted with three stakeholder groups: people with arthritis ( n = 10), healthcare professionals ( n = 18), and providers of community physical activity services ( n = 6). Participants were recr …

16.08.2026journal-article

Marlajar: Journal of Science, Technology, and Innovation

Cyberpsychological Analysis: The Effect of Emotional Regulation via Online Communities on the Quarter-Life Crisis Among Young People in Medan

Jansen Simbolon, Hotpascaman Simbolon

Early adulthood is a transitional period characterised by academic, career and work demands, interpersonal relationships, and uncertainty about the future, all of which can trigger a quarter-life crisis. This study aims to analyse the influence of emotional regulation on the quarter-life crisis and to identify the most dominant aspects of emotional regulation amongst young adults in the city of Medan. The study employed a quantitative approach using a simple linear regression design. The sample comprised 348 indivi …

16.08.2026journal-article

Metabolites

Dietary Inflammation, Gut Mycobiota, and Microbial Cross-Kingdom Associations with Cardiovascular Health in Older Adults

Yuchen Fu, Yuxiao Wu, Shuyue Wang, Xiaoyang An, Yong Li, Meihong Xu

Background/Objectives: Dietary inflammation may influence cardiometabolic health, yet the gut mycobiome and bacterial–fungal interactions remain unclear. Building upon our earlier findings and data from the TALENTs trial (Targeting Aging and Longevity with Exogenous Nucleotides) baseline data, we explored gut fungal profiles and bacterial–fungal co-occurrence patterns in relation to the Dietary Inflammatory Index (DII) and Life’s Essential 8 (LE8) in older adults. Methods: We enrolled 301 community residents aged 6 …

15.08.2026journal-article

Haemophilia

Understanding the Experiences of Young People Living With Haemophilia—A UK Social Media Study

Emma Gayton, Ranjit Nagra, Bekki Millward, Erin Plummer, Laura Galimam, Alex Dowsett, Nikki Curry

ABSTRACT Introduction Haemophilia is a rare congenital bleeding disorder that presents significant physical and psychological challenges, especially for young people, with limited real‐world evidence about their experiences in the UK. Aim This study sought to understand the perspectives and challenges of young people living with haemophilia in the UK by analysing social media conversations. Methods A retrospective qualitative study using social media listening was conducted, analysing publicly accessible UK‐based p …

15.08.2026journal-article

Revista ft

Sarcopenia e envelhecimento no Brasil: relação entre hábitos de vida, diagnóstico e progressão da síndrome - revisão sistemática

José Matheus Amaral, Gabriel Ribeiro dos Santos, Thiago Almeida de Paula, Lucas Rosendo da Silva

Objective: to analyze scientific publications and official documents regarding the relationship between lifestyle habits, diagnostic methods and progression of sarcopenia among older adults in Brazil. Method: systematic review without meta-analysis, structured according to PRISMA 2020 recommendations. The research question followed the PECO framework, considering Brazilian older adults, exposure to sedentary behavior, insufficient physical activity, dietary inadequacy and comorbidities, and outcomes related to risk …

15.08.2026journal-article

Journal of Dementia and Alzheimer's Disease

Fluid and Imaging Biomarkers in Lecanemab Therapy for Early Alzheimer’s Disease: Current Evidence, ARIA Risk Prediction, and Treatment Monitoring

Pan-Woo Ko

Background/Objectives: Lecanemab, a humanized anti-amyloid-β protofibril antibody, achieves substantial amyloid clearance and modest slowing of clinical decline in early Alzheimer’s disease (AD). Amyloid-related imaging abnormalities (ARIA) represent the most clinically important safety concern, yet no fluid biomarker has been prospectively validated for ARIA prediction in lecanemab-treated patients. This review critically synthesizes current evidence on fluid and imaging biomarkers for ARIA risk stratification and …

15.08.2026journal-article

REMUNOM

Desafios atuais na assistência multiprofissional à gestação e ao parto de pessoas com transtorno do espectro autista (TEA) e seus familiares

Debora Cristina Ferreira Ribeiro, Thalita Oliveira Santos, Anaisa de Carvalho Ribeiro, João Manoel Moreira Furtado, Leandro Saldanha Nunes Mouzinho

O Transtorno do Espectro Autista (TEA) pode repercutir de maneira particular na vivência da gestação, do parto e do puerpério, sobretudo em razão de aspectos relacionados à comunicação, à regulação emocional e às sensibilidades sensoriais, exigindo adaptações na assistência em saúde. Este estudo teve como objetivo descrever os desafios enfrentados pelos profissionais de saúde na assistência à gestação e ao parto de pessoas autistas e seus familiares. Trata-se de uma revisão narrativa da literatura, de caráter descr …

15.08.2026journal-article

Healthcare

Quality of Life, Active Ageing, Social Support and Loneliness in Older Adults Attending Day Centres: A Descriptive Analysis

Julia Sánchez-Galloso, Andrés Arana-Rodríguez, José-Luis Sánchez-Ramos, Almudena Garrido-Fernández, Rocío Romero-Serrano, Francisca María García-Padilla

Background/Objectives: Population ageing has increased the importance of promoting wellbeing and healthy ageing. Gerontological day centres may support the wellbeing of older adults. This study aimed to examine quality of life, active ageing, perceived social support, and loneliness in older adults attending gerontological day centres and to identify the factors associated with quality of life. Methods: A cross-sectional descriptive study was conducted with 109 participants aged 60–98 years recruited from gerontolo …

15.08.2026journal-article

Child and Adolescent Mental Health

Technology Matters: Integrating digital treatments for children and young people with anxiety disorders into routine care

Per Andrén, Kajsa Dellgran, Matti Cervin

Anxiety disorders in children and young people are common and impairing. Cognitive behavioural therapy (CBT) is the recommended first‐line treatment and the past two decades have seen numerous digital CBT interventions emerge. Digital CBT has the potential to improve access, reduce waiting times and scale services. However, guidance on how digital CBT should be integrated into routine care pathways remains limited. This article summarises current clinical guidelines for children and young people with anxiety disord …

15.08.2026journal-article

Interacting with Computers

Same trust, different paths: how older adults reach similar AI trust through use and non-use

Yimeng Wang, Alicia Hong, Yixuan Zhang

Abstract As AI systems become increasingly prevalent, older adults engage with them through diverse approaches, ranging from active use to deliberate non-use. But how does trust in AI differ across these orientations? Our explanatory sequential mixed-methods study, including a survey (n = 217) and interviews (n = 20), reveals a paradox: older adults who actively use AI and those who intentionally choose not to report similarly moderate levels of trust, yet arrive at that trust through fundamentally different pathwa …

15.08.2026journal-article

Medicine and ecology

Prevalence of arterial hypertension among people of working age in Karaganda and Ulytau regions in dependence on the place of residence and gender

T. S. Sergaliyev, E. Zh. Makhanbetchin, A. Sh. Kaipova, Sh. D. Dzhaketayeva, G. B. Shurina

Currently, arterial hypertension is considered as one of the most significant public health problems, since this disease is becoming more common among people of working age every year and leads to an increase in medical and economic costs. In the course of the study, the authors conclude that the prevalence of hypertension in Karaganda and Ulytau regions directly depends on the level of urbanization and regional characteristics: in urban, especially industrial areas, with a high incidence of hypertension, significa …

15.08.2026journal-article

Journal of Medicine and Palliative Care

Adjuvant chemotherapy patterns and clinicopathological factors associated with survival in patients aged 70 years and older with resected stage II–III colon cancer: a single-center real-world study

Zekeriya Hannarici, Aykut Turhan, Mehmet Emin Büyükbayram, Senar Ebinç, Alperen Akansel Çağlar, Mehmet Bilici, Salim Başol Tekin

Aims: Older adults are underrepresented in adjuvant colon cancer trials, leaving uncertainty regarding oxaliplatin benefit and optimal treatment duration. This study evaluated the associations of adjuvant chemotherapy patterns, treatment duration, and clinicopathological factors with overall survival (OS) and disease-free survival (DFS) in patients aged ≥70 years with resected stage II-III colon cancer.Methods: This single-center retrospective study included patients aged ≥70 years with resected stage II-III colon …

15.08.2026journal-article

People and Nature

The Symbiocene as a transformative vision

Tina Heger, Oliver Szasz

Abstract We live in times of crises and calls for a transformative social‐ecological change are voiced increasingly often. The question is, however, how such a transformation could be achieved. The prevailing view is that we are living in an era in which human activities significantly altered planet Earth: the Anthropocene. According to this narrative, humans are a very powerful force, turning the global situation for the worse. It has been argued that this view can cause disillusion and frustration, thus hampering …

15.08.2026journal-article

Public Organization Review

What Really Drives People-first Public-private Partnerships Adoption? Evidence From Resource-constrained Settings

Charles Ndandiko, Moses Mumbere Kalengyo, Peter Wanyama Obanda, Godfrey Mugurusi

Abstract This study examines the factors influencing the adoption of People-First Evaluation Methodology (PFEM) in Public-Private Partnerships (PPPs) operating within resource-constrained contexts. Using Partial Least Squares Structural Equation Modeling applied to survey data, the findings show that contracting authority support and staff awareness are a strong drivers of adoption, which in turnimproves PPP success in development phases. Compliance mechanisms and regulatory involvement facilitate adoption, althoug …

15.08.2026journal-article

Tạp chí Y học Dự phòng

Trí tuệ nhân tạo trong dự báo tái nhập viện do bệnh tim mạch ở người cao tuổi: Tổng quan từ y văn quốc tế

Thị Thanh Toàn Đỗ, Đỗ Thị Thanh Toàn, Ngô Gia Huy, Hà Mạnh Hiếu, Phạm Đức Kiên

Tái nhập viện do bệnh tim mạch ở người cao tuổi là một thách thức lớn đối với y tế công cộng. Nghiên cứunày thực hiện tổng quan với phạm vi 41 công bố quốc tế nhằm hệ thống hóa việc ứng dụng học máy trongdự báo nguy cơ tái nhập viện ở người bệnh từ 65 tuổi trở lên. Kết quả cho thấy suy tim là bệnh cảnh lâmsàng được nghiên cứu nhiều nhất, với cửa sổ dự báo 30 ngày là phổ biến nhất. Các mô hình cây quyếtđịnh và tăng cường (như Random Forest, XGBoost, LightGBM) cùng hồi quy logistic có điều chuẩn lànhững thuật toán đư …

15.08.2026journal-article

European Geriatric Medicine

Supporting geriatric thinking and management: adaptation of the Geriatrics 5Ms to Danish healthcare context

Lone Winther Lietzen, Rune Dall Jensen, Ryan Z. Chippendale, Anna Skovsbo Vamdrup-Andersen, Karen Andersen-Ranberg, Lene Holst Andersen

Abstract Purpose Coordinated, person-centred care for older adults is often challenged by multimorbidity, functional decline, and fragmented care trajectories. While Comprehensive Geriatric Assessment (CGA) remains the gold standard, its implementation outside specialised geriatric settings is limited. The Geriatrics 5Ms framework (mind, mobility, medications, multicomplexity, and matters most) offers a structured and accessible alternative. We aimed to adapt the Geriatrics 5Ms to the Danish healthcare context. Met …

15.08.2026journal-article

Journal of Medicine and Palliative Care

Clinical and laboratory features of geriatric patients with suspected immunodeficiency

Fikriye Kalkan, Begüm Görgülü Akın, Makbule Seda Bayrak Durmaz, Betül Özdel Öztürk, Şadan Soyyiğit

Aims: The increasing life expectancy of the global population has led to a growing number of older adults presenting with recurrent infections and suspected immune dysfunction. However, immunodeficiencies remain underrecognized in the geriatric population because clinical manifestations often overlap with age-related immune changes and multiple comorbidities. This study aimed to evaluate the clinical, laboratory, and immunological characteristics of elderly patients referred for suspected immunodeficiency and to in …

15.08.2026journal-article

Immunity & Ageing

CD8+ effector memory and regulatory T cell dynamics predict subclinical atherosclerotic plaque formation in healthy aging

Christopher Weyh, Vincent Größer, Luciele Guerra Minuzzi, Torsten Frech, Kristina Gebhardt, Svenja Nolte, Theresa Regine Dombrowski, Tim Böttrich, Manuela Andrea Hoffmann, Natascha Sommer, Robert Ringseis, Klaus Eder, Samuel Sossalla, Pascal Bauer, Karsten Krüger

Abstract Background Subclinical atherosclerotic plaque (SAP) develops silently in older adults. Biological changes that predict plaque formation are not well defined. We examined whether circulating immunological, metabolic, and functional measures identify vascular vulnerability before clinical disease. Methods In a three-year longitudinal study, 49 healthy older adults (63.8 ± 3.8 years) underwent carotid ultrasound, T cell phenotyping, serum protein profiling, body composition assessment, and fitness testing at …