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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Journal of Translational Medicine

Comprehensive review of myalgic encephalomyelitis/chronic fatigue syndrome

Madhan Jeyaraman, Naveen Jeyaraman, Swaminathan Ramasubramanian, Luise Schäfer, Filippo Migliorini, Sangeetha Balaji

Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex, debilitating disease that is unexplained and is characterised by persistent unexplained fatigue, Post Exertional Malaise (PEM), cognitive impairment, unrefreshing sleep and multisystem impairment. Despite the high burden of symptoms and the worldwide prevalence, ME/CFS has been poorly understood, underdiagnosed and underfunded. This large-scale review summarises the available evidence regarding the epidemiology, diagnostic progress, …

28.08.2026journal-article

Revista Contexto & Saúde

Entre avanços e lacunas: Avaliação de ações de puericultura na atenção primária de saúde no leste maranhense

Andréa Karla de Souza Gouveia, Vanessa Lorena da Silva Oliveira, Ana Letícia Araújo Portela Morais, Suelane Gabriel Mesquita, José Henrique Sampaio Batista, Rosângela Nunes Almeida, Maria Rita Pereira Moura, Lucas Santos Ribeiro, Francisca Chaves Moreno, Ana Carla Marques da Costa, Joseneide Teixeira Câmara

Objective: To analyze childcare actions in Primary Health Care (PHC) in eastern Maranhão, from the perspective of parents and caregivers. Method: A descriptive and evaluative study with a quantitative approach, carried out in the municipality of Caxias, Maranhão. The Primary Care Assessment Tool (PCATool), child version, validated by the Brazilian Ministry of Health, was used as an instrument to assess the essential and derived attributes of PHC, including first-contact access, longitudinality, comprehensiveness, c …

28.08.2026journal-article

Hacettepe University Faculty of Health Sciences Journal

Association Between Food Choice Motives and Food Consumption in Young Adults: Gender, Obesity and Stress-Related Differences Among University Students

Fatma Ilgaz, Mehmet Fisunoğlu

Objectives: This study was designed to determine the association between food choice motives and consumption of healthy and unhealthy foods in young adults, and to investigate if there is a difference in food choice motives between specific subgroups according to gender, obesity or the presence of depression, anxiety or stress. Material and Methods: The study was planned as a cross-sectional study, and 1000 undergraduate students enrolled in the 2017-2018 academic year were included. Data on students’ food choice p …

28.08.2026journal-article

Social Psychiatry and Psychiatric Epidemiology

Economic hardship and mental health following a national trauma and amid ongoing conflict: a longitudinal cohort study

Dana Katsoty, Yaakov Greenwald, Yuval Neria, Ariel Knafo-Noam, Ido Lurie

Abstract Purpose Exposure to war and terrorism increases the risk of mental health problems and often leads to economic hardship, which can further heighten psychological distress. This longitudinal study examined the extent of economic hardship experienced during the Israel–Hamas war following the October 7th terrorist attack, the severity of mental health symptoms over the first year of the war, and the associations and temporal directionality between economic hardship and mental health. Methods A representative …

28.08.2026journal-article

Russian Journal of Clinical Dermatology and Venereology

Spectrum of variants in the filaggrin gene in the Russian population and in patients with ichthyosis vulgaris

I.V. Zavarina, A.A. Kechin, O.V. Dolya, R.E. Mikheeva, N.A. Oskina, E.E. Baranova

Background. The filaggrin protein, encoded by the FLG gene, is key to maintaining a healthy skin barrier and normal immune system function. Filaggrin loss-of-function mutations are the primary cause of ichthyosis vulgaris, a common dermatological disorder. At the same time, high variability in individual variant frequencies between the studied populations and a large number of repeats in the third exon significantly complicate gene analysis using standard PCR methods. Objective. To examine the spectrum of genetic v …

28.08.2026journal-article

Healthcare

Organizational Support and Job Satisfaction of Nurses in Contemporary Clinical Practice: Indirect Associations Through Distributive Justice and Emotional Exhaustion

Marin Mamić, Nikolina Farčić, Slavka Galić, Vesna Ćosić, Ivana Mamić, Ivana Barać, Zvjezdana Gvozdanović, Goranka Rafaj, Silvija Marić, Ivan Vukoja, Robert Lovrić

Background/Objectives: Nurses’ job satisfaction is influenced by organizational conditions and psychological responses to demanding work. Although perceived organizational support, organizational justice, and burnout are established correlates of nurses’ work outcomes, less is known about how distributive justice and emotional exhaustion may operate simultaneously within the association between organizational support and job satisfaction. This study examined these two theoretically distinct indirect pathways. Metho …

28.08.2026journal-article

Nutrients

Pectin and Kaolin as Adjunctive Metabolic Therapy for Maintaining Remission in Ulcerative Colitis: Biological Rationale, Current Evidence and Future Clinical Perspectives

John K. Triantafillidis, Andreas Panayiotou, Apostolos E. Papalois

Background: Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease in which long-term maintenance of remission remains a major therapeutic challenge. Increasing evidence indicates that disruption of host–microbiome metabolic interactions, impaired production of short-chain fatty acids (SCFAs), defective epithelial energy metabolism, and intestinal barrier dysfunction contribute to disease relapse. These observations have generated interest in adjunctive metabolic strategies aimed at restoring lum …

28.08.2026journal-article

Frontiers in Public Health

Age-moderating effects and training characteristics of neuromuscular training for preventing knee injuries: a systematic review and meta-analysis

Youwei Yao, Ming Pan, Xuesong Niu

Objective Sports-related knee injuries are common and may cause pain, joint damage, reduced sport participation, and long-term physical activity limitations. Although neuromuscular training (NMT) is widely used for injury prevention, whether its effectiveness is moderated by age or intervention characteristics remains unclear. This systematic review and meta-analysis evaluated the effectiveness of NMT for preventing sports-related knee injuries and examined the influence of age and training characteristics. Methods …

28.08.2026journal-article

Cancer Medicine

Preoperative RDW –Albumin Ratio as a Prognostic Biomarker in Gastric Cancer Surgery

Xinhang Cao, Weiwei Shang, Dandan Xiao, Wei Wang, Ziyu Wang, Yangbai Sun, Yan Zhang, Mingzhe Ma

ABSTRACT Background The ratio of red blood cell distribution width (RDW) to serum albumin (RAR) combines hematologic and nutritional information from routine blood tests and has shown potential value for prognostication in several diseases. This study aimed to evaluate the prognostic significance of preoperative RAR in patients with gastric cancer undergoing curative gastrectomy and to explore whether RAR could provide additional prognostic information beyond conventional indicators such as TNM stage. Aims This stu …

28.08.2026journal-article

JAMA Network Open

Prediction of Treatment Benefit With Internet-Based Cognitive Behavioral Therapy for Depression

Cora Schefft, Heiner Stuke, Selin Demir, Maximilian Preiß, Lukas Pezawas, Jakob Kaminski, Björn Meyer, Steffen Moritz, Thomas Berger, Johanne Schröder, Jan Philipp Klein, Stephan Köhler

Importance Treatment benefit prediction models may help identify which patients will benefit most from internet-based cognitive behavioral therapy (iCBT) for depression; it is unclear whether such models can support useful treatment allocation across programs. Objective To develop a model predicting individual treatment benefit from iCBT for depression across programs and to externally validate it in independent samples. Design, Setting, and Participants This prognostic study used individual participant data from 5 …

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28.08.2026journal-article

Yassawi Journal of Health Sciences

METAPHYLAXIS OF NEPHROLITHIASIS: A PATHOGENETIC APPROACH USING MEDICINAL PLANTS AND LOCAL REMEDIES FROM SOUTHERN KAZAKHSTAN

M. Baydybekov M., B. Aitbayuly, A. Yernazarov, B. Baydybekov

Recurrent nephrolithiasis remains one of the most challenging problems in contemporary urology. This study presents a comprehensive, pathogenesis-based approach to metaphylaxis (prevention of recurrent stone formation) using medicinal plants, traditional beverages, and acidic mineral waters endemic to Southern Kazakhstan. Over a 12-year period, 500 patients with various forms of urolithiasis were treated using protocols developed based on the proteolysis–ion theory of stone formation. The study evaluated the effect …

28.08.2026journal-article

Processes

The Maieutic-H Model: Integrating Machine Learning-Based Prioritisation, Interaction Analysis, and Motivational Strategies for Scalable Healthcare Waste Management

Maria Assunta Cappelli, Eva Cappelli, Francesco Cappelli, Giovanni Marmora, Gianluigi Giorgetti, Giovanni De Feo

Healthcare waste mismanagement persists because the organisational and communicative dynamics driving erroneous practices remain largely unaddressed, particularly in high-turnover clinical units that concentrate the highest volumes of hazardous waste and operational pressure. Existing training interventions typically address motivational, analytical, or operational dimensions in isolation, lacking a systemic and adaptive framework. This study designs and theoretically validates Maieutic-H, a multilevel training eco …

28.08.2026journal-article

Medical Sciences

Mental Health Profiles in Children and Adolescents with Visual Impairment: The Role of Syndromic Etiology and Vision Severity

Mara L. Cordeiro, Tiago S. Bara, Vanessa Furlin, Daniel Almeida do Valle, Perola G. Iankilevich, Carolina Prando

Background: Visual impairment is associated with mental health difficulties in children, yet emotional and behavioral profiles across different etiologies and levels of visual impairment remain poorly characterized. We investigated whether these outcomes were associated with syndromic etiology or visual impairment severity. Methods: In this cross-sectional study, parents of 69 children and adolescents aged 6–17 years with visual impairment completed the Child Behavior Checklist (CBCL/6–18). Participants were groupe …

28.08.2026journal-article

New Zealand Medical Journal

How can we value what is not measured: the need for better data on women’s health and primary care

Fiona Imlach, Natalia Boven, Vanessa Selak

Decisions about healthcare funding and delivery in Aotearoa New Zealand, as well as the monitoring of health service performance and outcomes, are driven by readily available data, in particular from administrative health datasets. Most of these national health data collections are generated through the delivery of secondary health services. Further, apart from hospitalisation and mortality collections, these lack diagnostic coding, rendering the burden and cost of chronic health conditions predominantly managed in …

28.08.2026journal-article

Journal of Immigrant and Minority Health

Healthcare Services Use and Satisfaction Among Iraqi and Syrian Refugees in San Diego: A Qualitative Study

Nissma Bencheikh, Omar Barakat, Ariana Khayamian, Lana Bridi, Nour Makarem, Tala Al-Rousan

Abstract Arabic-speaking refugees in the United States face an elevated burden of chronic disease yet encounter significant barriers to care, and little research has examined their experiences in the U.S. primary care system. This study characterizes the patient experiences of Syrian and Iraqi refugees in San Diego to identify factors that enhance or hinder healthcare integration and satisfaction. Semi-structured interviews lasting 30 to 90 min were conducted in Arabic with 109 Syrian and Iraqi refugees residing in …

28.08.2026journal-article

Nutrition Bulletin

Plant‐Based Diet and Sleep Quality in Adults: Exploring the Role of Lifestyle and Health Mediators

Márcia de Oliveira Lima, Júlia Souza de Melo, Larissa de Lima Soares, Risia Cristina Egito de Menezes, Renan Serenini, Giovana Longo‐Silva

ABSTRACT This study investigated the association between plant‐based dietary indices (PDI) and sleep quality and examined the mediating roles of lifestyle and health‐related factors. A total of 5260 participants (18–65 years) were included. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). PDI—including overall (oPDI), healthy (hPDI), unhealthy (uPDI), and pro‐vegetarian diet index (PVDI)—was derived from a food frequency questionnaire covering 15 food groups. Associations between each PDI …

28.08.2026journal-article

Belitung Nursing Journal

Factors associated with extravasation severity in Thai patients receiving noncytotoxic intravenous infusions: An observational study

Thitiporn Pathomjaruwat, Borwarnluck Thongthawee, Padcha Pongcharoen, Charturong Tantibundhit

Background: Extravasation is a serious complication of peripheral intravenous (PIV) therapy. It has been linked to mechanical disruption of a PIV line due to inappropriate site selection or securement, and to the pH, concentration, and cytotoxic properties of the infused solution or drug. However, evidence on extravasation in patients receiving noncytotoxic drugs remains limited. Understanding the causes and risk factors in this population is essential for prevention, early detection, and the development of interve …

28.08.2026journal-article

Clinical and Experimental Dermatology

Extramammary Paget Disease: A Review

Farishta Khan, Shweta Karakara, Zhenghao Wang, Honey Frimpong-Manso, Birgitta van Bodegraven, Jane Sterling, Paul Craig, Andrew Nordin, Zoe C Venables

Abstract Extramammary Paget disease (EMPD) is defined by the World Health Organisation (WHO), as ‘a rare adenocarcinoma characterized by a predominant intraepithelial growth of neoplastic cells originating in the skin (primary EMPD) or representing intraepithelial spread of an underlying visceral carcinoma (secondary EMPD)’(1).It affects areas rich in apocrine glands, such as genital and perianal skin. First described by Radcliffe Crocker in 1889, EMPD often remains confined to the epidermis for years, following a …

28.08.2026journal-article

Academia Drug Development and Pharmacotherapy

Micelles in cancer nanomedicine: targeted delivery, imaging, and therapy

Amirhossein Rashnoodi, Zaynab Seraj, Niyoosha Zamani, Bahareh Khalili Najafabad

Despite advancements in oncology, conventional cancer therapies remain limited by poor specificity, systemic toxicity, and suboptimal therapeutic indices. Micellar nanostructures have emerged as a transformative platform to overcome these hurdles, leveraging their amphiphilic nature to encapsulate hydrophobic agents within aqueous biological environments. This review evaluates the current landscape of micelle-based technologies in cancer management, focusing on their integration into medical physics through diagnos …

28.08.2026journal-article

International Journal of Social Sciences and Public Administration

Criminal Law Protection Mechanisms for Virtual Property in Online Games under a Dual-Dimension Framework of Data and Property

Jiaran Zhang

The amount of money involved in online game platform digital assets is relatively large, but whether they should be regarded as electronic data or lawful property has not been clearly defined in Chinese enforcement practice. Two-level assessment will be used in this paper to show that there is a disagreement over whether data-related crimes fall under Articles 285-286 and whether asset-based crimes fall under Articles 264 and 266 of the Criminal Code . The Reference Standards for Sentences, Evidence and Valuation a …

28.08.2026journal-article

Annals of Public and Cooperative Economics

The market presence of cooperative banks and stability in European banking: New evidence

Hans Groeneveld

Abstract Most studies examining differences between cooperative banks (CBs) and other banking institutions rely on bank‐level data, thereby overlooking effects of the market presence of CBs on banking market structures. To address this gap, we test whether CB's domestic market share predicts national banking stability ( Z ‐scores) using a unique panel dataset for 15 European countries spanning 1991–2024 and a two‐way fixed‐effects framework. Our empirical findings confirm that CBs contribute to overall banking stab …

28.08.2026journal-article

International Journal of Social Sciences and Public Administration

Social Organizations’ Embedding in Grid-Based Governance: A Resource Dependence Perspective on Pathways and Mechanisms

Jiarui Ma

With the increasing complexity of grassroots governance and diversified social demands, traditional grid-based governance faces challenges such as insufficient governance resources and limited capacity for social participation. As an important actor connecting the state and society, social organizations have become increasingly involved in grassroots governance. Based on resource dependence theory, this study explores the pathways and mechanisms of social organizations’ embedding in grid-based governance. It argues …

28.08.2026journal-article

Journal of Pediatric Hematology/Oncology

Implementation of a Digital Clinical Management Platform in a Tertiary Pediatric Hemato-Oncology Center: Impact on Clinical Outcomes and Patient Safety

Michal Singer, Uri Ilan, Guy Dolinski, Nitsan Halabi, Yuliana Edri, Nisim Rahman, Sigal Sina, Maor Sagi, Sivan Tam, Moshe Ashkenazi

Introduction: Healthcare delivery is increasingly challenged by rising demand, escalating costs, and the need for efficiency. Contributing factors such as the nursing workforce crisis, fragmented and excessive clinical data, outdated IT infrastructures, and the growing complexity of care exacerbate the risk of medical errors, treatment delays, and staff burnout. To address these challenges, we evaluated AMIT, a novel digital platform designed to support nursing practice in pediatric oncology. Methods: AMIT is a web …

28.08.2026journal-article

APIK Journal of Internal Medicine

Efficacy of N-acetylcysteine in Acute Paraquat Poisoning: An Open-label, Parallel-group, Randomized Controlled Trial

Cheekatla Venkata Santosh, Mandip Singh Bhatia, Atul Saroch, Navneet Sharma, Neeraj Singla, Saurabh Chandrabhan Sharda

Abstract Background: Paraquat poisoning is associated with high mortality due to oxidative stress-induced multiorgan failure. No specific antidote is available. N-acetylcysteine (NAC) has shown potential benefit in preclinical studies, but robust evidence of its clinical efficacy is lacking. Objectives: This study was designed to evaluate the effects of intravenous NAC on organ dysfunction and mortality among patients with acute paraquat poisoning. Methods: We conducted an open-label, parallel-group, randomised con …