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22 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Farmatsevtychnyi zhurnal

Integration of artificial intelligence into health technology assessment: optimizing clinical analysis and synthesis of evidence on effectiveness and safety

I. A. Kostiuk

Clinical assessment is one of the most labor-intensive components of Health Technology Assessment, as it requires systematic literature retrieval, critical appraisal, and synthesis of scientific evidence. Recent advances in artificial intelligence have created new opportunities to optimize these processes; however, comparative analyses of artificial intelligence-based tools supporting the clinical component of Health Technology Assessment remain limited. The aim of the study was to systematize current evidence on t …

28.08.2026journal-article

Journal of Primary Care Dentistry and Oral Health

Applications of Artificial Intelligence in Pediatric Dentistry: A Narrative Review

Chiranjit Ghosh, Bhaswati Chakraborty, Amitava Bora, Pradip Kumar Mandal

Abstract Artificial intelligence (AI) is significantly transforming pediatric dentistry, offering advancements in diagnostic accuracy, treatment planning, and patient care. This narrative review explores the various applications of AI, including the detection of dental caries and supernumerary teeth, behavior management, and treatment planning for traumatic dental injuries. AI-driven tools, such as machine learning models and deep learning algorithms, enhance precision and efficiency in clinical practice. However, …

28.08.2026journal-article

PLOS One

A ribosomal marker-based metataxonomic framework for environmental surveillance of nematodes of public health importance

Juan P. Zuluaga, Katherine Bedoya-Urrego, Juan F. Alzate

Metataxonomic analysis targeting the V4 region of the 18S rDNA gene, combined with molecular phylogenetic inference, was applied to detect nematode DNA of public health relevance in environmental matrices. A total of 25 mOTUs corresponding to six nematode taxa were detected in environmental samples from the Andean region of Colombia. Analysis of 12 water and sludge samples from wastewater treatment plants, 5 artisanal agricultural bioinputs, and 3 food samples revealed multiple species of public health significance …

28.08.2026journal-article

Occupational and Environmental Medicine

Drug utilisation across occupations among pregnant women working in the healthcare and social assistance sector in France: a nationwide population-based study

Mélanie Araujo, Justine Bénévent, Christine Damase-Michel, Yolande Esquirol, Anna-Belle Beau

Objectives Medication use during pregnancy is common, but patterns may differ across occupational subgroups, particularly in healthcare and social assistance where working conditions, education and health literacy vary. We aimed to compare medications dispensed to pregnant women across occupations within this sector. Methods We conducted a nationwide population-based study using the French EDP-Santé database, linking occupational and socioeconomic data with healthcare reimbursement records. Pregnancies from 2009 to …

28.08.2026journal-article

Hacettepe University Faculty of Health Sciences Journal

Assessing Dietary Intake in Women: A Systematic Review of Gender-Specific Food Frequency Questionnaires

Ayşegül Kartal Acet, Zeynep Göktaş

Objective: To classify various food frequency questionnaires that have been developed and validated specifically for women.Materials and Methods: The researchers reviewed the available literature to identify food frequency questionnaires specifically developed and/or validated for non-pregnant women. To assess the validity and reproducibility of the questionnaires, correlation coefficients were examined between reference methods and FFQ estimates, as well as between repeated administrations of the same FFQs. System …

28.08.2026journal-article

RSV

A influência da fisioterapia sensório-motora nas unidades de terapia intensiva neonatal: ensaio teórico

Cesario Rui Callou Filho, Elisamara Silva da Cunha, Mirnis Aparecida Vieira de Macedo

Os benefícios da fisioterapia sensório-motora em unidades de terapia intensiva contribuem para melhores desfechos clínicos e redução de complicações relacionadas à hospitalização prolongada, como a imaturidade do sistema nervoso e a dificuldade de integração sensorial. OBJETIVO: Evidenciar as perspectivas atuais da influência da estimulação sensório-motora em recém-nascidos em unidade de terapia intensiva neonatal. MÉTODOS: Trata-se de um ensaio teórico desenvolvido por meio de pesquisas em bases eletrônicas, tais …

28.08.2026journal-article

Borneo Nursing Journal (BNJ)

Gambaran Indikator Diabetes Self-Management Questionnaire (DSMQ) pada Pasien Diabetes Melitus

Puja Akhlaqul Karimah, Isni Lailatul Maghfiroh, Aprelia Afidatul Hanafi

Self-management merupakan kemampuan pasien Diabetes Melitus dalam mengelola penyakit melalui manajemen glukosa, pengaturan pola makan, aktivitas fisik, dan pemanfaatan layanan kesehatan. Self-management yang baik berperan penting dalam mengendalikan kadar glukosa darah dan mencegah komplikasi. Penelitian ini bertujuan mengetahui gambaran indikator Diabetes Self-Management Questionnaire (DSMQ) pada pasien Diabetes Melitus. Penelitian ini menggunakan desain deskriptif dengan pendekatan cross sectional. Pada 50 pasien …

28.08.2026journal-article

Attahadi Medical Journal

Clinical, Epidemiological, and Laboratory Profiles of Mediterranean Spotted Fever among Pediatric and Adult Patients in Eastern Libya: A Retrospective Cohort Study

Arij Abdelgader

Mediterranean spotted fever (MSF) is a tick-borne rickettsiosis and continues to be endemic in the Mediterranean basin, but relatively little contemporary clinical data exist from Libya. This study characterized the epidemiological, clinical, laboratory, and seasonal profile of clinically diagnosed MSF and identified factors associated with severe disease. A hospital-based retrospective observational study was conducted among consecutive paediatric and adult patients managed at Al-Bayda Medical Center, Libya, from …

28.08.2026journal-article

BMC Nursing

Determinants of gout therapy non-adherence in patients attending an Egyptian rheumatology outpatient clinic

Samira Saad Ali, Samah Ramadan Shaheen Ibrahim, Manal Saeed Mohammed

Abstract Background Non-adherence to urate-lowering therapy (ULT) is a significant issue in the management of gout, a prevalent form of inflammatory arthritis that adversely affects patients’ quality of life and burdens healthcare systems. Although ULT is effective in reducing serum uric acid levels, many patients fail to adhere to their medication regimens. Factors contributing to this non-adherence include treatment complexity, medication costs, side effects, forgetfulness, and individual health beliefs, as well …

28.08.2026journal-article

Clinical Medicine (Russian Journal)

Iron accumulation in the heart of a patient with primary hemochromatosis type I (homozygous C282Y mutation of the HFE gene)

M.H.E. Laouar, R. V. Ponomarev, M. A. Kanunnikova, E. S. Neronova, N. T. Tynybekova, I. V. Tremzina, M. M. Malagina, A. B. Leonova, V. А. Baranova, E. O. Saakyants, A. A. Duktovskaya, P. A. Ovcharenko, A. N. Galagan, A. V. Vargo

Primary hemochromatosis results from pathogenic variants in several genes that can lead to increased iron stores in the body, with excess iron deposited in various organs including the liver, pancreas, and heart. Primary hemochromatosis is associated with homozygosity for the HFE p.Cys282Tyr mutation in 80% of cases. However, rare cases of hemochromatosis (nonHFE hemochromatosis) can be caused by pathogenic variants in other genes (such as HJV, HAMP, TFR2, and SLC40A1). Deposition of excess iron in parenchymal tiss …

28.08.2026journal-article

Clinical Medicine (Russian Journal)

Mathematical modeling of the expected effectiveness of empirical antibiotic therapy for peri-prosthetic infection

L. V. Lyubimova, E. A. Mikishanina, S. I. Pavlova, E. A. Lyubimov

Periprosthetic infection (PJI) is a serious problem in orthopedic practice. In the case of an unknown pathogen, empirical antibiotic therapy is based on local epidemiological data. The aim of this study is to calculate the expected effectiveness of empirical antibiotic therapy based on microbiological monitoring of PJI pathogens using mathematical modeling. Material and methods. A retrospective analysis of 379 bacterial isolates isolated in the PJI of the hip, knee and shoulder joints (2018–2024) was carried out. M …

28.08.2026journal-article

Southern African Journal of HIV Medicine

Rapid review of gender-affirming healthcare for children and adolescents: Evidence synthesis (2021–2025) and recommendations for South Africa

Ingrid Lynch, KL Dunkle, Chris McLachlan, Pierre Brouard, Landa Mabenge, Sakhile Msweli, Liberty Matthyse, Marion Stevens, Robin Dyers, Jenna-Lee de Beer-Procter, Kevin Adams, W.D. Francois Venter, Elma de Vries

Background: Since the publication of the Southern African HIV Clinicians Society Gender-Affirming Healthcare (GAHC) Guideline in 2021, global evidence on care for transgender and gender-diverse (TGD) youth has expanded. An updated, locally grounded, evidence-informed assessment of health outcomes can support South African stakeholders, particularly as both adolescents and TGD persons are populations of relevance to HIV prevention, sexual health, and integrated healthcare programmes in South Africa. Objectives: To s …

28.08.2026journal-article

New Zealand Medical Journal

Public support for cancer prevention and care policies in Aotearoa New Zealand: methods of a national survey

Bronwen McNoe, Andrew Gray, Ella Iosua, Rana Peniamina, Louise Signal

aim: Our aim was to describe the shared elements involving design, sampling, weighting and analytic framework of a national survey of public views on cancer prevention and care in Aotearoa New Zealand for the seven topic-specific brief reports in this issue of the New Zealand Medical Journal. methods: We conducted a nationwide, self-administered, cross-sectional online survey of adults aged 18 years or older between November and December 2025. Participants were recruited via an established online research panel usi …

28.08.2026journal-article

Frontiers in Medicine

Streptococcus suis meningitis complicated with communicating hydrocephalus: complete clinical and radiological resolution with non-neurosurgical management—A case report

Mei Qi, Yaqing Zeng, Bofu Ruan, Qin Wang

Background Streptococcus suis ( S. suis ) meningitis is a severe zoonotic central nervous system infection, with permanent sensorineural hearing loss as its most common long-term sequela. Hydrocephalus is an extremely rare and underrecognized complication of S. suis meningitis, and no case of communicating hydrocephalus secondary to S. suis meningitis managed successfully with non-neurosurgical therapy has been formally documented. Case presentation A 52-year-old man presented with 8 days of progressive dizziness a …

28.08.2026journal-article

INTERNATIONAL JOURNAL OF PUBLIC HEALTH RESEARCH AND DEVELOPMENT

HOUSEHOLD RISK FACTORS FOR LASSA FEVER TRANSMISSION IN HIGH- AND LOW-BURDEN STATES OF NIGERIA: A COMPARATIVE CROSS-SECTIONAL SURVEY

Olanrewaju Olaiya, Kayode Akanbi, Kwarbai Aaron Maitala, Adamu Ishaku Akyala, Islamiyat Adekemi Olatinwo, Abah Michael Idoko, Imaobong Udo Isang, Olasunkanmi Samson Coker

Lassa fever is a viral haemorrhagic fever endemic to Nigeria that exacts a heavy toll of morbidity and mortality annually. While Nigeria experiences annual outbreaks of the disease, household-level risk factors for transmission in areas of both high and low disease burden have not been fully described. The objective of this study was to evaluate and compare household risk factors for Lassa fever transmission in two high-burden (Ondo and Edo) and two low-burden (Bauchi and Ebonyi) states in Nigeria. Four states (sam …

28.08.2026journal-article

Seminars in Neurology

Clinical Syndromes of Peripheral Nervous System Neurotoxicity from Immune-Checkpoint Inhibitors

Isaac Smith, Minna Choi, Sakinah Sabadia

Abstract The introduction of immune checkpoint inhibitors (ICIs) has dramatically changed the landscape of treatment for a variety of cancers. However, there is increasing recognition of neurotoxicity related to ICI use. In this review, we will discuss the peripheral nervous system neurologic immune related adverse events (PNS-nirAEs) of anti-CTLA4, anti-PD1, and anti-PDL1 ICIs, including nerve, neuromuscular junction, muscle, and overlap syndromes. We will discuss the relevant epidemiology, pathophysiology, clinic …

28.08.2026journal-article

International Journal of Biology and Life Sciences

The Technical System, Clinical Application and Future Prospects of Pluripotent Stem Cells (ESC/iPSC) Mediated Nerve Regeneration

Daiyi Yang

This review systematically outlines the technological framework and clinical applications of neural regeneration mediated by pluripotent stem cells (ESCs/iPSCs). The article first compares the fundamental differences between the two: ESCs face ethical controversies regarding their embryonic origin and challenges related to immune rejection; while iPSCs support autologous transplantation, their reprogramming process may lead to genomic abnormalities, and the presence of residual undifferentiated cells poses a tumori …

28.08.2026journal-article

International Journal of Pharmacy Practice

A qualitative exploration of barriers and enablers to providing autonomous independent pharmacist prescribing for common clinical conditions in community pharmacy

Lorna Brown, Rachel Bruce, Pamela Macintyre

Abstract Introduction In 2020, a national Pharmacy First Plus (PF+) service was introduced in Scotland to enhance healthcare access by enabling community pharmacists with an independent prescribing qualification to diagnose, manage and autonomously prescribe for a wider range of common clinical conditions. Data demonstrated service delivery is variable. Objectives This study aimed to explore the barriers and enablers to delivering PF+ by community pharmacies within National Health Service Greater Glasgow & Clyde (N …

28.08.2026journal-article

Frontiers in Veterinary Science

The One Health teaching clinic as an interprofessional education learning environment: an Austrian community case study of veterinary PhD students' competency development through co-design with pre-service science teachers

Ulrich Hobusch, Sascha Krebser, Franziska Messenböck, Sebastian Linnartz, Veronika Fraisl, Eva-Maria Bartl, Damien Ernst, Pia Maria Saria, Kristina Schmidhofer, Simona Winkler, Christine Aurich, Martin Scheuch

One Health education increasingly requires competencies that conventional veterinary doctoral training does not systematically cultivate, including science communication with non-scientific audiences, transdisciplinary collaboration, and the ability to translate specialized research into societal and educational contexts. This community case study examines how five veterinary PhD students at the University of Veterinary Medicine Vienna experienced the One Health Teaching Clinic (OHTC), a 13-week interprofessional i …

28.08.2026journal-article

JAMA Health Forum

Medicaid Work-Reporting Requirements Under HR 1 and Insufficient or Inconsistent Work Hours

Paul R. Shafer, Timothy H. Callaghan, David M. Anderson

Importance House Resolution 1 (HR 1) of the 119th US Congress (2025-2026), known as the One Big Beautiful Bill Act, created national work-reporting requirements for adult Medicaid expansion enrollees starting by January 1, 2027. Although many expect the administrative burdens associated with work-reporting requirements to be the primary source of disenrollment, the impact of variable work hours and/or part-time work on potential disenrollment from Medicaid among low-income working adults is unknown. Objective To as …

28.08.2026journal-article

Journal of Smart Algorithms and Applications (JSAA)

A Comprehensive Review of Artificial Intelligence for Lumbar Spine MRI Analysis and Clinical Assessment

Marwa Abdelrahman, Ahmed Abd El Basset, Ahmed A. Elngar

Lower back pain is one of the major diseases to disability worldwide, with lumbar intervertebral disc degeneration (IVDD), disc herniation (DH), and lumbar spinal stenosis (LSS) being the most common underlying causes. Magnetic resonance imaging (MRI) is the imaging modality of choice for assessing these conditions; however, conventional MRI interpretation continues to be time-consuming, subjective, and prone to considerable interobserver variability. Recent advances in artificial intelligence (AI), particularly de …

28.08.2026journal-article

International Journal for Quality in Health Care

Development and validation of a machine learning–based model for predicting fall-related injury risk in hospitalized patients

Shiyu Wang, Xiaomei Zhang, Yi Qin, Xiuqun Xu, Linjing Du, Panpan Xu, Jiahui Yu, Yanqing Li, Lingyan Yang

Abstract Background Falls are among the most common adverse events in hospitalized patients, with about 30% leading to injury. We developed a machine learning model to predict which in-hospital fall events would lead to patient injury, thereby supporting post-fall risk stratification. Methods We retrospectively analyzed data from 410 patients who had experienced falls at a tertiary general hospital in China. Among them, 134 patients (32.7%) had fall-related injuries. The dataset was divided into training and test s …