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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

Sexual Health

Prevalence and risk factors of current hepatitis C infection among men who have sex with men aged 20–59 years: NHANES 1999–2016

Yan Zhang, Jiewei Liu, Yihao Lin, Agins Bruce, Yangyang She, Hongbo Jiang

Background Men who have sex with men (MSM) are a key population with a higher prevalence of hepatitis C virus (HCV) infection than the general population. Our study estimated the prevalence of current HCV infection and identified risk factors among MSM aged 20–59 years in the US from 1999 to 2016. Methods Data were obtained from the 1999–2016 National Health and Nutrition Examination Survey (NHANES). Current HCV infection was defined as having a positive HCV RNA test result. The prevalence of current HCV infection …

27.08.2026journal-article

Frontiers in Psychology

The mediating role of self-perceived health and fitness in the relationship between physical activity and quality of life among individuals with physical disabilities: the moderating effect of self-esteem

Majed M. Alhumaid

Background This study sought to investigate the psychological mechanisms that connect physical activity (PA) to quality of life (QoL) in individuals with physical disabilities (IWPDs). Three hypotheses were tested: (1) self-perceived health and self-perceived fitness mediate distinct indirect associations involving PA, self-perceptions, and QoL; (2) self-esteem moderates the indirect association between PA and QoL through self-perceived fitness; and (3) an integrated model, including PA level, self-perceptions, and …

27.08.2026journal-article

Supportive Care in Cancer

Coordination of care in the context of primary brain tumors: Australian healthcare professionals’ exploration of the unspoken impact and clinical implications

Megan S. Jeon, Hannah Isaac, Joanne Shaw, Dianne M. Legge, Sharon He, Thomas Carlick, Eng-Siew Koh, Georgia K. B. Halkett, Brian Kelly, Mark B. Pinkham, Raymond J. Chan, Tamara Ownsworth, Haryana M. Dhillon, for the BRAINS Investigator Group, Meera Agar, Thea Blackler, Helen Haydon, Robyn Leonard, Anna Nowak, Kerryn Pike, Nicole Rankin, Ursula Sansom-Daly, Joel Rhee, Annie Miller, Kristi Milley, Mona Faris, Rachel Campbell, Katarzyna Lion, Jill Chen, Tiffany Fazon, Melinda Lyne, Sian Virtue-Griffiths, Jessica Buster, Emma McDougall

Abstract Aim People with primary brain tumor (PBT) and their families experience high distress and face challenges navigating their disease and treatment, healthcare systems, and/or survivorship. Quality brain tumor care coordination (BTCC) enables continuous, timely care according to the individual care needs of patients. We aimed to explore healthcare professionals’ (HCPs) practices and perceptions of BTCC. Methods We conducted semi-structured interviews with 12 HCPs (92% female) working with people with PBT from …

27.08.2026journal-article

Healthcare

Development and Psychometric Evaluation of the Military Cadets’ Mental Health Risk Scale (MCMHRS) in Chinese Military Academy Cadets

Feifei Wang, Jia Guo, Guoyu Yang

Background: Military academy cadets face training, study, and adaptational pressures that elevate the risk for mental health problems and functional impairment. Existing tools are either generic symptom checklists or narrow resilience scales; none integrates environmental risk, individual vulnerability, and protective resources within a unified hierarchical model relevant to this population. Methods: We developed and psychometrically evaluated the Military Cadets’ Mental Health Risk Scale (MCMHRS). After item gener …

27.08.2026journal-article

Reports

Verification Index for the Repositioning of a Single Implant Analog in the Correct Place: A Clinical Technical Case Report

Socratis Thomaidis

Background and Clinical Significance: Implant impressions can present inaccuracies, affected by many factors, such as impression technique, impression material, and parallelism or lack thereof among the implants. The use of a verification index can assess the accuracy of the mastercast and can be used in order to adjust the inaccuracy of the mastercast. This article presents a technical variation in established verification-index procedures, followed by implant analog repositioning, which can be used in case of an …

27.08.2026journal-article

Nursing & Health Sciences

Walking Together: A Cross‐Cultural Study of the Relationship Between Religiosity and Substance Use Disorder

Camila Chagas, Leonardo Breno Martins, Tassiane Cristine Santos de Paula, Wellington Zangari, José Carlos Fernandes Galduróz

ABSTRACT The literature suggests that religiosity is a protective factor for substance use. However, individuals with substance use disorder (SUD) may actively cultivate their religiosity during substance use. This qualitative study analyzed the perceptions and meanings homeless people attribute to their substance use trajectories and religiosity, as well as the potential connections between these two themes. The analysis was conducted based on the content analysis technique proposed by Bardin. A total of 40 semi‐s …

27.08.2026journal-article

Neuro-Oncology

145 Implementing Vorasidenib in Clinical Practice: A Single-Centre Real-World Service Evaluation

Brooke Smart, Lorna Raymond, Antonia Creak, Liam Welsh, Ella Nicklin, Matteo Isolani, Ozofu Omuemu, Francesca Solda, Nicola Rosenfelder

Abstract Introduction The phase 3 INDIGO trial demonstrated significantly improved progression-free survival with Vorasidenib in patients with residual/recurrent IDH-mutant grade 2 oligodendroglioma and astrocytoma, supporting its integration into routine neuro-oncology practice. We undertook a real-world service evaluation at the Royal Marsden Hospital to assess toxicity, monitoring burden, and implications for wider UK implementation ahead of the anticipated appraisal by the National Institute for Health and Care …

27.08.2026journal-article

Molecules

Explainable Artificial Intelligence Assisted Modeling of Malachite Green Adsorption onto SBA-15–Zn–Fe Composite

Memduha Ergüt, Salih Ozbay, Seda Karateke, Metin Zontul

Dye-containing industrial effluents pose substantial risks to aquatic ecosystems. In this study, a material prepared using the stated SBA-15–Zn–Fe synthesis procedure was evaluated for malachite green (MG) removal and modeled using machine-learning and explainable artificial intelligence techniques. The dataset comprised 315 experimental observations covering initial MG concentrations of 100–500 mg L−1, adsorbent concentrations of 0.5–3.0 g L−1, pH values of 5–9, temperatures of 25–45 ∘C, and contact times of 0–360 …

27.08.2026journal-article

Research in Psychotherapy: Psychopathology, Process and Outcome

Psychological adaptation and health-related quality of life in inflammatory bowel disease: a 5-year follow-up study

Gabriella Martino, Emanuele M. Merlo, Carmelo M. Vicario, Federica Bellone, Clara De Francesco, Ulla Feldt-Rasmussen, Antonino Catalano, Walter Fries, Orlando Silvestro

Inflammatory bowel disease (IBD), encompassing Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic immune-mediated gastrointestinal condition in which long-term care increasingly involves patient-reported health, emotional functioning, and psychological adaptation. Because psychological adaptation may not parallel clinical remission, this 5-year longitudinal study examined changes in psychopathological symptoms, alexithymia, coping strategies, and health-related quality of life (HR-QoL) in 73 outpatients …

27.08.2026journal-article

Sensors

Improved Fusion of Optical Flow and Dead Reckoning for UAV Navigation Using Digital Terrain Models and Data-Driven Velocity Correction

Jakub Walczak, Piotr Targowski, Szymon Chmielewski, Sebastian Łeska, Janusz Furtak

Accurate velocity estimation in GPS-denied environments remains a core challenge for autonomous unmanned aerial vehicle (UAV) navigation. Our previous work demonstrated that fusing optical flow (OF) with dead reckoning (DR) substantially reduces position drift compared to inertial-only solutions. However, velocity estimates derived from dense optical flow are degraded by two systematic effects: (1) incorrect metric scaling when the camera footprint covers heterogeneous terrain types—particularly at forest–field tra …

27.08.2026journal-article

The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences

Reproductive life course histories and menopausal outcomes at midlife: Evidence from the National Longitudinal Study of Adolescent to Adult Health

Brianah M McCoy, Stephanie M Koning, Kathleen Mullan Harris, Lauren Gaydosh

Abstract Objectives Menopause is a heterogeneous transition that varies in timing and type, yet population-based research rarely considers how reproductive life course experiences shape menopausal outcomes. This study examines whether reproductive timing, reproductive history, and reproductive health across adolescence and adulthood are associated with menopausal status, early menopause, and surgical menopause at midlife. Methods Using data from women in Waves I–VI of the National Longitudinal Study of Adolescent t …

27.08.2026journal-article

Nutrients

Development and Internal Validation of a Clinical Risk Score for Hypovitaminosis D in Italian Adults Aged ≥50 Years Attending Osteoporosis and Metabolic Bone Disease Centers

Ranuccio Nuti, Luigi Gennari, Bruno Frediani, Stefano Gonnelli, Daniela Merlotti, Carla Caffarelli, Giovanni Minisola, Antonino Catalano, Nazzarena Malavolta, Monica Pinto, Giulia Letizia Mauro, Vito Mascolo, Cristiano Maria Francucci, Vincenzo Vinicola, Anna Capozzi, Maria Punzo, Orazio Falla, Luca Dalle Carbonare, Serena Guiducci, Rosario Coltraro, Agostino Gaudio, Domenico Maria Carlucci, Alessandra Randazzo, Eleonora Mastria, Colin Gerard Egan, Mariangela Morelli, Giovanni Tripepi

Background/Objectives: Hypovitaminosis-D is a highly prevalent condition worldwide, associated with adverse skeletal and extra-skeletal outcomes. Increasing demand for serum 25-hydroxyvitamin D (25(OH)D) testing points toward the need for simple tools to identify individuals at risk and optimize laboratory use. We aimed to develop and validate a clinical risk score for predicting hypovitaminosis-D based on easily assessable risk factors. Methods: This cross-sectional study included 1408 adults aged ≥50 years (1286 …

27.08.2026journal-article

Health Research Journal of Indonesia

Hubungan Perilaku Merokok dengan Kejadian Hipertensi Wilayah Kerja Puskemas Lamunti, Kecamatan Mantangai, Kabupaten Kapuas

Siti Rosaidah, Tien Aminah

Hipertensi merupakan masalah kesehatan utama yang meningkatkan risiko penyakit kardiovaskular, stroke, gagal ginjal, dan kematian, dengan perilaku merokok sebagai salah satu faktor risiko yang dapat dimodifikasi. Penelitian ini bertujuan menganalisis hubungan perilaku merokok dengan kejadian hipertensi di Wilayah Kerja Puskesmas Lamunti. Penelitian menggunakan metode kuantitatif dengan desain korelasional dan pendekatan cross-sectional. Populasi berjumlah 485 penderita hipertensi yang berkunjung ke Puskesmas Lamunt …

27.08.2026journal-article

Health Research Journal of Indonesia

Hubungan Pengetahuan dengan Kepatuhan Minum Obat Hipertensi di Wilayah Kerja UPT Puskemas Mantangai, Kalimantan Tengah

Eka Fitriani, Musthika Wida Mashitah

Hipertensi merupakan penyakit kronis yang memerlukan kepatuhan minum obat secara berkelanjutan untuk mencegah komplikasi. Pengetahuan yang memadai mengenai hipertensi dan pengobatannya berperan penting dalam meningkatkan kepatuhan pasien terhadap terapi sehingga tekanan darah dapat dikendalikan secara optimal. Penelitian ini bertujuan untuk mengetahui hubungan antara pengetahuan dengan kepatuhan minum obat pada pasien hipertensi di Wilayah Kerja Puskesmas Mantangai. Penelitian ini menggunakan desain kuantitatif den …

27.08.2026journal-article

Clinical Cancer Research

Adrenergic regulation of cancer immunity

Jingjing Zhu, Pierre-Hubert Desimpel, Constance Gérard, Benoit J. Van den Eynde

Abstract The nervous and immune systems engage in extensive bidirectional crosstalk that shapes tumor progression and therapeutic response. Among the neuro-immune pathways involved in cancer, adrenergic receptor signaling has emerged as a key regulator of the tumor microenvironment. In this review, we summarize current understanding of the distinct roles of β- and α2-adrenergic receptor signaling in cancer immunity and their therapeutic implications. β2-adrenergic receptor signaling promotes immune suppression by i …

27.08.2026journal-article

Journal of Craniofacial Surgery

Upper Eyelid Blepharoplasty Reduces Perceived Age: An Artificial Intelligence-Based Analysis

Zeynep Erdoğan Çetin, Begüm Yılmaz, Ahmet Can Çiftçi

Upper eyelid blepharoplasty is a commonly performed procedure for periorbital rejuvenation; however, objective evaluation of its aesthetic outcomes remains limited. This study aimed to assess changes in perceived age following upper blepharoplasty using an artificial intelligence (AI)-based age estimation model. In this retrospective cohort study, patients who underwent isolated upper blepharoplasty between January 2022 and January 2025 were included. Standardized preoperative and postoperative (3–6 mo) facial phot …

27.08.2026journal-article

Frontiers in Public Health

Lung cancer screening in occupational settings: a scoping review

Edelqueen Ijeoma Okoro, Helena Keller, Felix Greiner, Jan Heidrich, Volker Harth

Background Lung cancer is the leading cause of cancer-related mortality worldwide. It is often asymptomatic until advanced stages, resulting in delayed diagnosis and poor survival. Screening enables early detection and reduces mortality. Multiple occupational and environmental exposures have been linked to lung cancer, and some guidelines recommend their inclusion in risk assessment. This review aims to map the existing evidence on lung cancer screening (LCS) in occupational settings. Methods This review followed J …

27.08.2026journal-article

Clinical Journal of the American Society of Nephrology

Proteinuria and Kidney Function Trajectories in Patients with Advanced CKD

Cheol Ho Park, Hyun Jun Hong, Hyung Woo Kim, Jung Tak Park, Tae Ik Chang, Tae-Hyun Yoo, Sue K. Park, Jung Soon Kim, Kyu-Beck Lee, Jong Cheol Jeong, Kook-Hwan Oh, Amanda H. Anderson, Wei Yang, Jordana B. Cohen, Mahboob Rahman, Shin-Wook Kang, Seung Hyeok Han, on the behalf of CRIC Study and KNOW-CKD Investigators

Introduction: While urine protein-to-creatinine ratio (UPCR) is more commonly used than urine albumin-to-creatinine ratio in routine care, and particularly in low-resource settings; its association with kidney function decline and projected time to reach a kidney failure estimated glomerular filtration rate (eGFR) threshold in advanced chronic kidney disease (CKD) remains underexplored. Methods: We analyzed 2,727 participants with eGFR 15–45mL/min/1.73 m 2 without kidney replacement therapy (KRT) from the Chronic R …

27.08.2026journal-article

Journal of Clinical Medicine

Clinical and Functional Outcomes Following Repeat VA-ECMO in Adults: A Propensity Score–Matched Comparative Study

Kostiantyn Kozakov, Alois Philipp, Maik Foltan, Henrik Heuer, Walter Petermichl, Alexander Dietl, Bernhard Flörchinger, Leopold Rupprecht, Simon Schopka, Christof Schmid, Zdenek Provaznik

Background/Objectives: Evidence on outcomes after repeat VA-ECMO in adults remains limited. This study aimed to compare survival and post-discharge functional outcomes between adults requiring a second VA-ECMO run and propensity-matched patients supported with a single VA-ECMO run and to characterize the clinical course during repeat support. Methods: This is an observational, single-center, retrospective cohort study with a propensity score–matched comparative analysis, conducted at a university tertiary-care refe …

27.08.2026journal-article

Journal of Clinical Medicine

Frequency and Systemic Associations of Focal Low-Trabeculation/Low-Density Intramedullary Jawbone Findings: A Retrospective CBCT Study

Marzena Dominiak, Wojciech Niemczyk, Artur Pitułaj, Witold Świenc, Sebastian Dominiak, Konstanty Sławecki, Łucja Janek, Jacek Matys

Background: This exploratory study assessed the frequency of study-defined focal low-trabeculation/low-density intramedullary findings (FLDIFs) in a selected clinical cohort referred for cone-beam computed tomography (CBCT) and examined their associations with demographic, systemic, and radiographic variables. CBCT depicts mineralized trabecular architecture and relative attenuation but cannot directly demonstrate marrow fat or establish osteonecrosis; FDOJ/MFI were therefore considered only possible interpretation …

27.08.2026journal-article

Longitudinal and Life Course Studies

Characterising residential mobility during childhood in the United Kingdom: a longitudinal study using linked electronic health records

Nicola Firman, Laura North, Jane Lyons, Marta Wilk, Michael Edwards, Rhodri D. Johnson, Rowena Bailey, Jo Davies, Gill Harper, Carol Dezateux, Richard Fry, Lucy J. Griffiths

Background: Childhood residential mobility (RM) has been associated with adverse health and social outcomes. We examined differences in RM by family size and household composition in two diverse, disadvantaged UK populations. Methods: Using electronic health records (EHRs) and anonymised addresses, we examined if household characteristics are associated with RM in north-east London (NEL) and Wales. We conducted a longitudinal study of 240,509 (51.0 per cent male) and 398,959 (51.3 per cent male) children aged 0–13 …

27.08.2026journal-article

Journal of Applied Clinical Medical Physics

Evaluating the preoperative diagnostic value of 99m Tc‐MIBI/ 99m TcO 4 − dual‐isotope SPECT/CT fusion imaging and ultrasonography in suspected primary hyperparathyroidism

Yanmei Li, Danna Hou, Zhehao Lyu, Xingrong Lan, Ziyue Zhang, Yu Lu, Peng Fu, Huiqi Gao

Abstract Background Primary hyperparathyroidism (PHPT) is a common endocrine disorder that often requires surgical intervention. Preoperative localization of parathyroid lesions is critical for successful surgery. This study compares the diagnostic value of 99m Tc‐MIBI/ 99m TcO 4 − dual‐isotope SPECT/CT fusion imaging and ultrasonography (US) in patients with suspected PHPT, and explores the correlation between lesion volume and preoperative serum biochemical markers. Objective This study aimed to assess the preope …

27.08.2026journal-article

Transactions on Social Science, Education and Humanities Research

The Legal Path of Digital Technology Driving the Modernization of Border Ethnic Affairs Governance

Kaixin Zheng, Li Wei

The modernization of border ethnic affairs governance driven by digital technology is an inevitable requirement arising from the overlapping strategies of national governance modernization and Digital China construction. Based on the three-dimensional analytical framework of "technology-institution-value", this paper systematically interprets the legal basis and practical landscape of digital empowerment for border ethnic affairs governance, analyzes the in-depth legal dilemmas faced by the current governance trans …

27.08.2026journal-article

Journal of Central Banking Theory and Practice

Central Bank Digital Currencies and Bank Deposit Dynamics: Evidence from Cross-Country Difference-in-Differences Analysis

Piotr Misztal

Abstract The emergence of central bank digital currencies (CBDCs) represents one of the most significant innovations in contemporary monetary systems. As central banks explore digital forms of sovereign money, an important question concerns how CBDC introduction may affect the structure of financial intermediation, particularly the role of commercial bank deposits. Because CBDCs constitute a direct claim on the central bank, their availability may alter the allocation of liquid assets held by households and firms a …