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Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
10.08.2026journal-article

Journal of Intellectual Disabilities

Intellectual disabilities and risk of dementia: A Korean population-based cohort study

Yoo Jin Um, In Young Cho, Hye Yeon Koo, Yong-Moon Mark Park, Kyung Mee Kim, Chung Eun Lee, Kyungdo Han

This retrospective cohort study assessed the risk of all-cause dementia, Alzheimer’s disease (AD), and vascular dementia (VaD) in individuals with intellectual disabilities compared to those without. Using data from the Korean National Disability Registry and National Health Insurance Service, individuals over 40 who underwent health examinations in 2009 were followed until 2020. Cox proportional hazards models estimated hazard ratios (HRs) for dementia outcomes, adjusting for confounders. Over a mean 8-year follow …

10.08.2026journal-article

Oral Diseases

Fractal Analysis of Periodontal Tissues in Geriatric Patients With Different Periodontal Conditions: A Retrospective Study

Dilek Ozkan Sen, Omer Ogutcen, Fatma Ucan Yarkac, Ibrahim Burak Yuksel, Muhammet Emin Arslan, Zeynep Tastan Eroglu

ABSTRACT Objective This study evaluated the relationship between fractal dimension (FD) values and periodontal status in geriatric patients using digital panoramic radiographs. Methodology In this retrospective observational study, 147 elderly individuals were classified as periodontally healthy ( n = 30), gingivitis ( n = 32), Stage I periodontitis ( n = 26), Stage II periodontitis ( n = 14), Stage III periodontitis ( n = 20), and Stage IV periodontitis ( n = 25) according to the 2017 World Workshop Classification …

10.08.2026journal-article

Frontiers in Psychology

Intelligent health management technology use and depressive symptoms among older adults: the serial mediating roles of physical activity and social adaptation

Xiagang Song, Zhenjiang Tian

Objective This study examined the association between intelligent health management technology (IHMT) use and depressive symptoms among older adults in China, focusing on the mediating roles of physical activity and social adaptation. Methods Using data from the 2023 China Longitudinal Aging Social Survey, this cross-sectional study included 10,300 older adults aged 60 years and above. A serial mediation model was estimated using the PROCESS macro (Model 6) in SPSS 25.0. The significance of the indirect effects was …

10.08.2026journal-article

npj Dementia

Ensuring access to Tau-Targeting therapies for MAPT frontotemporal dementia: patient community priorities for regulators and industry

Linde Jacobs, Cure MAPT FTD, Tanya Steel, Barbara Dawson, Barbara Frommell, Annika Roll, Marian Grems

Abstract MAPT Frontotemporal Dementia (FTD) is a rare and devastating neurodegenerative disease caused by genetic mutations leading to tau aggregation. This document outlines seven key requests that Cure MAPT FTD, a nonprofit patient advocacy organization, made on May 23, 2025 in a Patient Listening Session to the U.S. Food and Drug Administration (FDA) regarding clinical trial design and the approval of tau-targeting therapies for MAPT FTD patients. The recommendations were informed by a community survey of 44 pat …

10.08.2026journal-article

Frontiers in Public Health

Parental socioeconomic position, childhood poverty and healthy aging: retrospective and prospective study of six cohorts across 32 wealthy and developing nations

Gindo Tampubolon

Background and aim Children who were poor in wealthy countries have reported worse cognitive, muscle, and mental functions, as well as greater frailty and multimorbidity, in later life. However, it remains unclear whether those who were poor in childhood worldwide fall short of healthy aging, as information on childhood conditions is often unreliable. Here, I present new evidence on the lifecourse shaping of healthy aging among older adults worldwide. Methods Some 80,000 older adults aged 50 and over in 32 wealthy …

10.08.2026journal-article

Frontiers in Neurology

Person-centered non-pharmacological interventions for agitation in dementia: a meta-analysis with subgroup analysis by behavioral subtypes

Ruilong Ye, Mengqing Lin, Lingjun Lei

Objective This meta-analysis aimed to evaluate the overall efficacy of person-centered non-pharmacological interventions for agitation in dementia and to compare treatment effects across behavioral subtypes, specifically physical aggressive agitation, physical non-aggressive agitation, and verbal agitation. Methods A systematic literature search was conducted in PubMed, Embase, Web of Science, and the Cochrane Central Register of Controlled Trials (CENTRAL) from database inception to March 2026. Randomized controll …

10.08.2026journal-article

The British Journal of Psychiatry

Improving outcomes for people with co-occurring autism and psychosis: from diagnostic overshadowing to system-wide clinical capability

Andrew J. Watson, Kathryn M. Taylor, Demelza Tootill, Vaughan Bell

Summary Individuals with co-occurring autism and psychosis are poorly supported by current psychiatric systems yet commonly present to both autism and psychosis services. Diagnostic overshadowing, fragmented pathways and unadapted interventions drive poorer outcomes. Psychosis services must embed neurodevelopmentally informed assessment, formulation, staff training and routine treatment adaptations to deliver equitable, effective care for this underserved population.

10.08.2026journal-article

AIDS Research and Human Retroviruses

Efficacy and Safety of Albuvirtide Plus Dolutegravir or Dolutegravir/Lamivudine in Hospitalized People with Advanced AIDS: A Retrospective Real-World Study

Huanxia Liu, Yuanhong He, Tongtong Yang, Lin Cai, Yuan Yuan, Chunrong Lv, Shenghua He

Hospitalized people with advanced AIDS require potent, safe antiretroviral therapy (ART) with minimal drug interactions. This real-world retrospective cohort study aims to evaluate the efficacy and safety of albuvirtide (ABT) plus dolutegravir (DTG), with or without lamivudine (3TC), in this vulnerable population. We retrospectively analyzed clinical data from treatment-naïve (TN) and treatment-experienced (TE) hospitalized people with AIDS who received an ABT-based regimen for at least 24 weeks at the Chengdu Publ …

10.08.2026journal-article

Current Alzheimer Research

Dynamic Entropic Mapping of Alzheimer’s Neuropathology: Eyes-Open and Eyes-Closed EEG Biomarkers through Wavelet Entropy Analysis

Yujiao Tong, Guanqun Hu, Lingfeng Liu, Ying Zhang, Nan Jiang, Ying Hou, Meiyun Zhang

Background: Alzheimer’s Disease (AD) is characterized by amyloid-β plaques and tau tangles, while current diagnostic tools are often invasive and costly. Electroencephalography (EEG) offers a non-invasive alternative, with alpha rhythm abnormalities as key features. Impaired alpha reactivity during the transition from Eyes-Closed (EC) to Eyes-Open (EO) reflects early thalamocortical dysfunction. Objective: This study employs EO/EC wavelet entropy analysis to assess neurodynamic features across frequency bands, aimi …

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10.08.2026journal-article

BMC Medicine

Remission of long-term conditions among adults with multiple long-term conditions in England primary care: A retrospective cohort study of 4.7 million people

Aman Jat, Benjamin D Barton, Rohini Mathur, Beth Stuart, Hilda Hounkpatin, Hajira Dambha-Miller

Abstract Background Multiple long-term conditions (MLTC) are increasingly prevalent among UK adults, yet the extent to which remission of long-term conditions is recorded in routine primary care remains poorly understood. Accurate documentation of remission has implications for clinical management, disease trajectories, and the use of electronic health records in research. Examining remission in the context of MLTC is important because remission in one condition may alter overall disease burden and treatment needs …

10.08.2026journal-article

International Journal of MS Care

Perspectives on End of Life and Medical Assistance in Dying From Saskatchewan People With Multiple Sclerosis

Janine Brown, Katherine B. Knox, Lilian Thorpe, Loralee Herter, Mir Nabila Ashraf, Michael C. Levin, Ilia Poliakov

Background: Medical assistance in dying (MAID) is a legally available option in Canada. Bill C-14 determined initial eligibility requirements (eg, a patient having a reasonably foreseeable natural death), program safeguards, and a definition of who can assess and administer MAID. Subsequently, Bill C-7 removed the requirement that death must be reasonably foreseeable. Saskatchewan’s multiple sclerosis (MS) prevalence rate is among the highest in the world, and some individuals with MS have already accessed MAID. Th …

10.08.2026journal-article

Australian & New Zealand Journal of Psychiatry

Unplanned health service utilisation among people living with cancer and mental health conditions: A retrospective matched case-comparison study in Australia

Ramya Walsan, Reema Harrison, Huah S. Ng, Eng-Siew Koh, Sabe Sabesan, Ashfaq Chauhan, Anita Vandyke, Natalie Taylor, Elizabeth Manias, Tim Badgery-Parker, Rebecca Mitchell

Background: Mental health conditions are associated with inequities across the cancer pathway, yet differences in unplanned health service use remain poorly described. This study examined sociodemographic, clinical and virtual care use factors associated with unplanned health service use among adults living with cancer, with and without mental health conditions. Methods: A retrospective matched case-comparison study was conducted using linked data from three Australian states. Adults aged ⩾ 18 years with cancer wer …

10.08.2026journal-article

Zamonaviy jamiyat va innovatsiyalar ilmiy-nazariy jurnali

YOSHLARDA HUQUQIY ONG TUSHUNCHALARINI SHAKLLANTIRISHNING IJTIMOIY-PSIXOLOGIK XUSUSIYATLARI

UMIDA OLIM QIZI FAYZIYEVA

This article examines the socio-psychological characteristics of shaping legal consciousness and legal culture among youth, the mechanisms of attitude formation towards laws, and methods for preventing legal nihilism. The paper highlights the role and importance of cognitive, emotional, and behavioral factors in enhancing legal literacy among young people. Furthermore, it analyzes the impact of educational institutions, the family environment, and the digital information space on an individual's legal worldview. Pr …

10.08.2026journal-article

Journal of the American Geriatrics Society

Comparative Effectiveness, Safety, and Costs of Gabapentinoids in Older Adults With Long‐Term Opioid Use

Kevin T. Pritchard, Chun‐Ting Yang, Qiaoxi Chen, James M. Wilkins, Dae Hyun Kim, Kueiyu Joshua Lin

ABSTRACT Background It is unclear whether managing chronic pain with adjuvant gabapentin versus pregabalin can safely reduce long‐term opioid use among older adults. Our objective was to compare clinical effectiveness, safety, and costs of initiating gabapentin versus pregabalin. Methods We conducted a retrospective cohort study and target trial emulation in a US National sample of 2013–2018 Medicare fee‐for‐service and 2004–2024 Optum's de‐identified Clinformatics Data Mart Database (Optum CDM). Participants inclu …

10.08.2026journal-article

Arthritis Care & Research

Clinician and Patient Factors Associated With Long‐Term Glucocorticoid Use in People With Rheumatoid Arthritis Receiving Advanced Therapies

Michael D. George, George Reed, Matthew D. Kearney, Peter F. Cronholm, Kevin Kane, Jeffrey R. Curtis, Dimitrios A. Pappas, Joel M. Kremer

Objective Despite guideline recommendations, long‐term glucocorticoid (GC) use is common in rheumatoid arthritis (RA). We conducted a clinician survey nested within a large registry to identify patient and clinician factors associated with GC use. Methods Clinicians contributing patients to the CorEvitas Rheumatoid Arthritis Registry were surveyed between 2023 and 2024, capturing demographics, medication safety concerns, and a range of other attitudes. We then identified patients with RA initiating a new biologic o …

10.08.2026journal-article

Asian Journal of Social Health and Behavior

Pupil–galvanic Skin Response Synchrony during Family-centered Visual Reminiscence in Older Adults with Cognitive Impairment: A Proof-of-concept Study

Cheng-Ren Chen, Jung-Ying Hou, Hui-Ching Weng

Abstract Introduction: Subtle changes in attention and emotion characterize early cognitive decline. In Asian elders, where family is central, culturally tailored reminiscence therapy (RT)-inspired visual stimulation may amplify autobiographical engagement. We aimed to determine whether visual–autonomic coupling, assessed through eye-tracking and galvanic skin response (GSR), serves as a sensitive physiological indicator of cognitive vulnerability during family-centered, RT-inspired visual stimulation. Methods: Thi …

10.08.2026journal-article

Revista Chilena de Rehabilitación y Actividad Física

Efectos del entrenamiento multicomponente sobre síntomas psicológicos-conductuales y funcionalidad en una persona con enfermedad de alzheimer residente en una zona insular: estudio de caso único

Jéssica Sepúlveda Molina, Caroline Zamorano Sánchez

Psychological and behavioral symptoms are common in patients diagnosed with dementia, especially Alzheimer's disease (AD), leading to functional impairments. Previous studies evaluating the effects of multicomponent training on these psychological and behavioral symptoms are inconsistent. Objective: To evaluate the effect of a multicomponent physical training program on the psychological and behavioral symptoms (PBS) and functional status of a person with Alzheimer's disease residing in an island region. Method: A …

10.08.2026journal-article

Frontiers in Psychology

Evaluation of smart TV user interfaces for older adults based on the perception assessment method of analytic hierarchy process (AHP)-fuzzy theory

Ting Zhang, Rosalam Che Me, Hassan Alli

With the deepening of population aging in China, smart TVs have become the most frequently used home digital device for older adults, serving as their core channel for daily information access and entertainment. However, the mismatch between older adults’ perceptual needs, declining sensory and cognitive abilities, and the complex interface design of smart TVs has severely exacerbated the digital divide among this group. Existing studies mostly focus on qualitative age-appropriate design strategies, and lack a targ …

10.08.2026journal-article

Epilepsia

Cross‐material memory prediction: Influence of preoperative visual memory on postoperative verbal memory change after left anterior temporal lobe resection in people with epilepsy

Lea Marie Reisch, Anne Hagemann, Johanna Lena Hopf, Florian J. Muecke, Friedrich G. Woermann, Christian G. Bien, Philip Grewe

Abstract Objective Left anterior temporal lobe resection (TLR) in people with epilepsy is associated with a high risk of postoperative verbal memory decline. Whereas substantial evidence supports the role of preoperative verbal memory in predicting postoperative verbal memory change, the potential contribution of preoperative visual memory has been rarely investigated. Methods We retrospectively analyzed data from 105 people with left TLR due to mesial temporal sclerosis and typical language dominance. Multiple lin …

10.08.2026journal-article

Journal of Applied Gerontology

eHealth Interventions for Dementia in Ethnic Minority Groups: A Scoping Review

Isabeau Van Rompuy, Hannah Christie, Penelope Siebert, Marjolein de Vugt

This scoping review examines literature on eHealth interventions for the dementia care triad, people with dementia, informal carers, and healthcare professionals that were developed or culturally adapted to address the needs of ethnic minority groups. Following PRISMA-ScR guidelines, searches were conducted in PubMed, PsycINFO, Scopus, Embase, and Google. Studies published before 2007 or in languages other than English or Dutch were excluded. Thematic analysis revealed an increase in publications since 2015, mainly …

10.08.2026journal-article

Journal of Sandwich Structures & Materials

Study of flexural performance degradation in neat and flax-fibre-reinforced PLA gyroid sandwich panels under humid/dry aging cycles

Guido Di Bella, Mohamed Chairi, Giuseppe Scionti, Luigi Calabrese

This study investigates the flexural durability of FFF-printed gyroid-core sandwich structures made from neat PLA and PLA-flax under accelerated humid/dry aging. Both materials were printed using the same sandwich configuration, with a gyroid core of 10 mm cell size and 20% infill density. Specimens were exposed to 0, 200, 400, 600, 800, and 1000 cycles, alternating between dry conditions at 40 ± 2°C and 10 ± 5% RH and humid conditions at 23 ± 2°C and 85 ± 5% RH. Three-point bending tests showed that both materials …

10.08.2026journal-article

International Journal of Social Sciences & Cultural Studies

The Evolving Sociology of the Family in Sierra Leone: Changing Patterns Due to Economic Pressures, Technology, Aging Populations, and New Forms of Kinship in Sierra Leone

Emmurana Morray

In this article, I explore the ways in which the sociology of families in Sierra Leone is changing considering economic pressures, accelerated adoption of technology, demographic shifts (including local aging), and the rise of “flexible” or “chosen” kinship networks. This is a secondary evidence synthesis (not a primary or mixed-methods field study): it integrates quantitative sources (national statistics, household surveys, and administrative indicators) with qualitative sources (ethnographies and case studies). Q …

10.08.2026journal-article

Geriatrics

Factors Associated with 30-Day Non-Return to Pre-Hospital Residence in Older Patients Hospitalized with Pneumonia or Lower Respiratory Tract Infection: The Role of Serum Albumin and Early Treatment Failure

Akira Goto, Takayoshi Hozuki, Akihiro Matsumura, Hiroaki Mita, Norikazu Iwata, Emiko Tsuda, Ikumi Ebisu, Kazumi Yonekura, Susumu Kikuchi, Masahiro Nakamura, Yukinari Yoshida, Yuji Hinoda, Hiroo Yuasa, Yasuo Kato

Background/Objectives: Return to the pre-hospital residence is a meaningful patient-centered outcome after hospitalization for pneumonia or lower respiratory tract infection (LRTI). We examined factors associated with 30-day non-return, including prespecified baseline characteristics, the initial empirical antimicrobial therapy pattern, and initial treatment failure within 7 days. Methods: This retrospective observational study included 126 consecutive patients aged ≥65 years admitted with pneumonia or LRTI to a co …

10.08.2026journal-article

Jurnal Keperawatan Bunda Delima

Hubungan Self Care Management dengan Kualitas Tidur Lansia Hipertensi

Khasanah Setyawati, Widiyono, Ni’mah Mufidah, Indriyati

Pendahuluan: Hipertensi ditandai oleh keadaan tekanan darah yang berada di atas kisaran normal yaitu tekanan sistolik sebesar 130–139 mmHg dan tekanan diastolik 80–89 mmHg. Pada kelompok lansia, peningkatan kejadian hipertensi berkaitan dengan belum optimalnya penerapan selfcare management dalam mengendalikan tekanan darah. Kurangnya pemenuhan selfcare management menyebabkan penurunan kualitas tidur. Pada lansia, terjadi penurunan fungsi organ sehingga lansia memerlukan selfcare management dan kualitas tidur yang b …