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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
17.08.2026journal-article

Journal of Rehabilitation Medicine

Mapping the commonalities of rehabilitation: using GUIDE-rehab to open the black box of programmes across diverse health conditions

Stefano Negrini, Helena Burger, Paolo Capodaglio, Maria Gabriella Ceravolo, Lisa Hoogendam, Esther Janssen, Greta Jurenaite, Calogero Malfitano, Federico Pennestri, Ruud Selles, Gianluca Martino Tartaglia, Charlotte Kiekens

Objective: Rehabilitation is a health strategy implemented with specific programmes across multiple health conditions. This study aimed to identify rehabilitation programmes’ commonalities among health conditions and partners, as required by the PREPARE (Personalised REhabilitation via Novel AI PAtient StRatification StratEgies) project. Design: Qualitative study. Subjects/Patients: Seven rehabilitation programmes in Europe covering diverse health conditions were chosen according to PREPARE research needs for their …

17.08.2026journal-article

East African Journal of Agriculture and Biotechnology

Effects of Agricultural Rehabilitation Programme on Enhanced Value Chain: The Roles of Farmers’ Willingness and Commitment to Participate

Emmanuel Agyekum, Wiiliam Mills Abbey, Gloria Pokuaa-Duah

This study investigates the impact of the Cocoa Rehabilitation Programme (CRP) on the Enhanced Value Chain (EVC) within the Ghanaian cocoa sector. Central to this inquiry is the role of human agency, specifically examining how Farmers’ Willingness to Participate (FWP) and Farmers’ Commitment to Participate (FCP) function as psychological and behavioural mediators between institutional interventions and value chain optimisation. Drawing on the Theory of Planned Behaviour (TPB) and Value Chain Theory, the research de …

17.08.2026journal-article

The Egyptian Journal of Critical Care Medicine

Vitamin C deficiency and its effect as adjuvant therapy in sepsis patients

Eslam Abdelhady, Mohammed Ashraf Shawky, Mahmoud Khaled Nour, Farouk Mostafa Fares

Abstract Background Sepsis causes high mortality and organ failure; vitamin C deficiency is common and may worsen inflammation and shock, supporting its role as an adjunctive therapy. Objectives To evaluate plasma vitamin C levels in sepsis and septic shock and assess the effects of high-dose intravenous vitamin C on inflammation, hemodynamics, organ dysfunction, and clinical outcomes. Methods This prospective, interventional, non-randomized controlled cohort study was conducted in the 25-bed Critical Care Departme …

17.08.2026journal-article

Journal of Asian Pacific Society of Cardiology

Current Diagnostic Practices and Management Strategies for Cancer Therapy-related Cardiac Dysfunction: An Exploratory Multicentre Survey in Indonesia

Feny Junaidy, Mefri Yanni, Citra Kiki Krevani, Hirowati Ali

Background: Cancer therapy-related cardiac dysfunction (CTRCD) has emerged as a major complication of modern cancer therapy, particularly as cancer survival continues to improve. Although international guidelines provide standardised recommendations for CTRCD surveillance and management, real-world implementation remains highly variable, especially in low- and middle-income settings. Key diagnostic modalities include left ventricular ejection fraction and global longitudinal strain, ideally integrated within a mult …

17.08.2026journal-article

Biomacromolecules

Mucoadhesive Carboxymethyl Chitosan Hydrogel Eyedrops via Dual Dynamic Covalent Chemistry for Long-Acting Glaucoma Therapy

Jin Pan, Huangkun Gong, Qiuyun Shao, Xuehan Zhang, Ravin Narain, Kaihui Nan, Yangjun Chen

Abstract Glaucoma, a leading cause of irreversible blindness, is commonly treated with topical eye drops that reduce intraocular pressure (IOP), but their efficacy is limited by rapid precorneal clearance. To address this, we developed a dynamic hydrogel (CSFP) via Schiff base bonding between carboxymethyl chitosan (CMCS) and 4-formylphenylboronic acid (FPBA) as an advanced delivery vehicle for brimonidine (BRI) and timolol (TIM), two common IOP-lowering agents. The mechanical properties were tunable by adjusting C …

17.08.2026journal-article

JMIR Mental Health

Interpretable Topic Modeling of Spontaneous Speech in Depression Using Large Language Models: Multilingual Four-Cohort Study

Gustave Cortal, Sélim Benjamin Guessoum, Xuan-Nga Cao, Santiago de Leon-Martinez, Enrique Baca-García, Rachid Riad

Abstract Background Depression is underdiagnosed worldwide, and clinicians rely on interpreting patients’ subjective speech. Qualitative analysis of patient language does not scale, and existing computational approaches describe topics with keyword lists that miss clinical nuance. Objective We evaluated whether clustering spontaneous speech transcripts with large language models (LLMs) yields clusters whose membership is associated with validated clinical scales across multilingual cohorts, and whether LLMs can ren …

17.08.2026journal-article

Frontiers in Urology

Use of androgen suppression therapy at salvage radiotherapy in recurrent prostate cancer: a systematic review with meta-analysis

Maria Juliana Chaves Medina, Rodolfo Varela Ramírez, Wilfredo Donoso Donoso, Jaime Moreno-Chaparro, Javier Eslava-Schmalbach

Introduction Salvage radiotherapy (SRT) is one of the treatment options after progression following surgical management, with effectiveness varying according to patient risk and clinical-pathological characteristics. Objective To compare the effectiveness of SRT alone versus SRT combined with androgen deprivation therapy (ADT) in men with biochemical recurrence. Methods We conducted a systematic review with advanced searches in MEDLINE (PubMed), EMBASE, SCOPUS, Cochrane CENTRAL, and LILACS for the period 1990–2024. …

17.08.2026journal-article

Pacing and Clinical Electrophysiology

Non‐Invasive Methods for Identifying Electrical Responders to Conduction System Pacing Cardiac Resynchronization Therapy

Jack W. Samways, Nadine Ali, Ahran D. Arnold, Ji‐Jian Chow, Matthew Shun‐Shin, Jagdeep Singh Mohal, Akriti Naraen, Keenan Saleh, Nandita Kaza, Chetanya Sharma, Pavel Leinveber, Pavel Jurák, Daniel Keene, Yixiu Liang, Nicholas S. Peters, Prapa Kanagaratnam, James P. Howard, Norman Qureshi, Fu Siong Ng, Nick W. Linton, David C. Lefroy, Darrel P. Francis, P. Boon Lim, Mark A. Tanner, Amal Muthumala, Frits W. Prinzen, Judith M. Lubrecht, Karol Čurila, Graham Cole, Zachary Whinnett

ABSTRACT Background Conduction system pacing (CSP) is an emerging alternative modality of cardiac resynchronization therapy (CRT). However, not all patients obtain electrical resynchronization with CSP, there is a clinical need for reliable non‐invasive predictors of response. We aimed to assess the ability of several non‐invasive modalities to predict electrical resynchronization with CSP‐CRT. Methods Patients with standard heart failure CRT indications (excluding right‐bundle branch block) underwent CSP‐CRT using …

17.08.2026journal-article

Occupational and Environmental Medicine

Increased risk of occupational falls among cancer survivors: Japanese nationwide cohort

Kazuhiko Watanabe, Ichiro Kawachi, Takahiro Tabuchi, Masayoshi Zaitsu

Objectives Despite declining incidence rates for some cancers, the ageing workforce and improved survival have increased the number of workers with a history of cancer. Cancer treatment can affect strength, balance and bone health, thereby increasing fall risk among cancer survivors. However, an association between a history of cancer and occupational falls has not been reported. We aimed to investigate whether a history of cancer was associated with occupational falls and fall-related fractures among workers in Ja …

17.08.2026journal-article

ACS Biomaterials Science & Engineering

ROS-Responsive, Water–Oil Biphasic Hydrogel-Based Separable Microneedle System for Intra-Articular Delivery in Osteoarthritis Therapy

Xian Zhang, Na Li, ChengRong Zhang, XiaoQing Zhang, Yanhong Ma, Huan Ye, Xin Wang, Guoqing Yan

Abstract Osteoarthritis (OA) is characterized by a chronic inflammatory microenvironment with excessive reactive oxygen species (ROS) and progressive cartilage degeneration. To address these challenges, we developed a ROS-responsive, water–oil biphasic separable microneedle patch (CKCA MN) for transdermal therapy. This microneedle utilizes hyaluronic acid (HA) as a rapidly dissolving substrate, and its needle tip comprises a coordination-crosslinked hydrogel formed by Ce3+ and alendronate (Aln), loaded with cinnama …

17.08.2026journal-article

JAIDS Journal of Acquired Immune Deficiency Syndromes

Use of Long-acting Injectable Antiretroviral Therapy in Kidney and Liver Transplant Recipients with HIV

Christine Durand, Sarah Hussain, Sabrina Kopf, Shikha Mehta, Navya Eleti, Meenakashi Rana, Valentina Stosor, Sander Florman, Jonathan Hand, Nathaniel Erdmann

Background: The 2013 HIV Organ Policy Equity Act facilitated HIV-to-HIV organ transplants, enabling people with HIV to receive transplants more quickly. However, managing drug interactions between ART and immunosuppressive regimens remains a challenge. Objective: This study assesses the safety and effectiveness of cabotegravir/rilpivirine (CAB/RPV), an injectable ART, in maintaining HIV virologic suppression in kidney and liver transplant recipients. Methods: A retrospective review of three clinical studies evaluat …

17.08.2026journal-article

Applied Sciences

Telemonitoring Technologies for Breast Cancer Rehabilitation: A Narrative Review of Digital Health Solutions

Lorenzo Lippi, Alessio Turco, Matilde Rosalia Picco, Stefano Moalli, Mauro Nascimben, Lia Rimondini, Alessandro de Sire, Marco Invernizzi

Long-term functional impairments, including deficits in upper limb mobility, cancer-related fatigue, and reduced physical performance, are often reported by breast cancer survivors, underlining the need for sustainable and easily accessible rehabilitation techniques. Telemonitoring technologies have shown promising results in extending rehabilitation outside of clinical settings. However, the increasing number of technological solutions make it difficult to outline the optimal approach in the comprehensive manageme …

17.08.2026journal-article

NeuroRehabilitation

Beyond the Diagnosis: An Integrated Perspective on Strategic Dosing in Neurologic Motor Rehabilitation. A Scoping Review and Collaborative Viewpoint

Ahmad Rifai Sarraj, Jihan Allaw, Fadi Zein El Abidin, Antonio Pinti

Background Current neurorehabilitation often relies on static, diagnosis-driven protocols or generic exercise administration, contributing to suboptimal long-term outcomes. There is a clinical need for a cohesive, mechanism-based framework to guide therapeutic reasoning, dosing, and longitudinal adaptation. Methods A scoping review of neurorehabilitation literature was conducted according to PRISMA-ScR guidelines to map evidence on dosing, intensity, and longitudinal management. From 9,373 records, 42 studies were …

17.08.2026journal-article

International Journal of Innovative Science and Research Technology

Parental Satisfaction with Occupational Therapy Services at Niepmd

Kurinji Chelvan S., Dukhu Aman Murmu

Background: Parental satisfaction with occupational therapy services is a key indicator of service quality and effectiveness, especially in institutions catering to individuals with disabilities. The National Institute for Empowerment of Persons with Multiple Disabilities (NIEPMD) plays a pivotal role in providing specialised therapeutic services. Understanding parents' perspectives on these services can help identify strengths and areas for improvement, ultimately enhancing therapeutic outcomes.  Aim: To assess p …

17.08.2026journal-article

Occupational and Environmental Medicine

Occupational noise exposure and risk of myocardial infarction: results from a prospective Swedish cohort

Claudia Lissåker, Mattias Sjöström, Theo Bodin, Maria Albin, Jenny Selander

Objectives To explore the association between occupational noise exposure the preceding year and myocardial infarction (MI) and cumulatively. Methods Data came from the Swedish National Cohort on Work and Health, a cohort of all Swedish individuals born between 1930 and 1990. We included individuals with at least one occupational code between 1985 and 2013, which was matched to a job-exposure matrix for occupational noise in five categories (LAeq8h): <70, 70–74, 75–79, 80–84, ≥85 dB(A). First-time MI was ascertaine …

17.08.2026journal-article

International Journal of Computer Information Systems and Industrial Management Applications

IMPACT OF KEY DIMENSIONS OF OCCUPATIONAL STRESS ON JOB SATISFACTION AMONG TRAFFIC POLICE IN TELANGANA AND ANDHRA PRADESH

K. Nagaraju, P. Saritha

Traffic police personnel operate under demanding conditions involving prolonged duty hours, technological requirements, financial concerns, environmental exposure, public interaction, and operational challenges. This study examines the influence of occupational stress on job satisfaction among traffic police personnel in Telangana and Andhra Pradesh using a multidimensional framework. The study considers Job-Related Stress (JRS), Technology-Related Stress (TRS), Financial-Related Stress (FRS), Environmental and Phy …

17.08.2026journal-article

Revista de Geopolítica

AVALIAÇÃO DO DESENVOLVIMENTO NEUROPSICOMOTOR DE CRIANÇAS PRATICANTES DE EQUOTERAPIA

Fabiola Freire Candido Santos, Jasmim Crislayne Costa Martins, Gustavo Coringa de Lemos, Joelma Gomes da Silva Rocha, Rebeca Graziely Gomes de Melo, Frederico da Silva Jales, Andréa Raquel Fernandes Carlos da Costa, Lidiane Pinto de Mendonça Ferreira, Sirlene Batista Cavalcante, Natália Jéssica Barra Silva

O presente estudo teve como objetivo avaliar o impacto da equoterapia no desenvolvimento neuropsicomotor de crianças entre 3 e 17 anos atendidas no município de Mossoró/RN. A equoterapia, abordagem terapêutica interdisciplinar, utiliza o cavalo como agente terapêutico, promovendo estímulos motores, sensoriais e emocionais que contribuem para o desenvolvimento biopsicossocial. Trata-se de pesquisa descritiva e transversal, de abordagem quantiqualitativa, realizada de agosto a outubro de 2024. Foram avaliadas criança …

17.08.2026journal-article

Adolescência e Saúde

Dealing And Resisting Verbal Aggression In (Husband-Wife) Abusive Relationships Through Cognitive Behavioral Therapy: Reading Meena Kandasamy And Krishna Sobti’s Fiction

Rufus Ruth Livingston Jakki, Boddu Chandrashekar

Verbal aggression within marriage remains one of the least visible forms of domestic abuse despite its severe psychological consequences for women. In patriarchal societies, emotional humiliation, coercive communication, and linguistic domination frequently become normalized within marital relationships. This study examines the representation of verbal aggression and emotional resistance in When I Hit You: Or, A Portrait of the Writer as a Young Wife by Meena Kandasamy and Mitro Marjani by Krishna Sobti through the …

17.08.2026journal-article

Modern Rheumatology Journal

Successful experience with divozilimab therapy for systemic sclerosis

M. N. Starovoitova, O. V. Desinova

Systemic sclerosis (SSc) is a severe rheumatic disease characterized by high mortality and reduced quality of life. Over the past 10–15 years, the treatment paradigm for SSc has changed dramatically owing to a better understanding of its pathogenesis, the accumulation of evidence supporting the efficacy of immunosuppressants, and the emergence of targeted therapies. B lymphocytes are considered to play a key role in disease development through their effects on fibroblast activation and autoantibody production, maki …

17.08.2026journal-article

Journal of Medicinal Chemistry

Structure-Based Design of First Ndc80 Loop-Targeting Peptide Disrupting Ndc80–Nuf2 Interaction for Hepatocellular Carcinoma Therapy

Xing Jin, Miao-Miao Niu, Yifei Geng, Liqiao Han, Yuting Wang, Xianzhang Huang, Qiaoxuan Zhang

Abstract Ndc80 is essential for kinetochore–microtubule attachment, but its broad protein–protein interaction interface remains difficult to target. Here, we used structure-guided peptide optimization to develop Peptide-4, a loop-directed peptide designed to modulate the Ndc80–Nuf2 interaction. In contrast to reported Ndc80-directed compounds acting through the Hec1–Nek2 axis or the calponin homology domain, Peptide-4 addresses an underexplored loop region. Peptide-4 bound Ndc80 with a Kd of 0.45 ± 0.01 nM and inhi …

17.08.2026journal-article

Small

A Dual GSH/ROS‐Functional NIR Fluorescent Platform for Synergistic Photodynamic Therapy and Radiosensitization in Nasopharyngeal Carcinoma

Fan Zheng, Yan Mo, Jin Zhou, Chengmin Li, Min Lin, Yingqi Zhao, Jingmei Zhou, Hui Zou, Zhikang Chen, Runsha Xiao, Xueping Feng, Wenbin Zeng

ABSTRACT High‐precision tumor theranostic systems capable of real time monitoring are imperatively required for optimizing the spatial targeting accuracy during radiotherapy and surgical resection across clinical management of nasopharyngeal carcinoma (NPC). However, the clinical application of photodynamic therapy (PDT) is impeded by the suboptimal reactive oxygen species (ROS) generation efficiency and inadequate visualization of redox procedure. In this study, we developed a theranostic platform HSF , featuring …

17.08.2026journal-article

International Journal of Innovative Science and Research Technology

Physiotherapy Management of Chronic Temporomandibular Joint Dysfunction in a Cricket Player: A Case Report

Anoli Gupta, Sneha Ganu

Background: Temporomandibular dysfunction (TMJ) is a commonly seen maxillofacial disorder in athletes, with a predominance in females. Contact sports are a contributing factor to TMJ dysfunction, such as blows to the jaw. In recent years, physiotherapy has had excellent outcomes.  Case Presentation: A 19-year-old male cricket player came in with a complaint of limited jaw opening and a click on jaw movements after suffering a blow to the jaw. Based on clinical examination, he was diagnosed with Internal derangemen …

17.08.2026journal-article

PHAGE: Therapy, Applications, and Research

Prevalence of Biofilm-Forming Pseudomonas aeruginosa from Clinical Samples in Africa: A Systematic Review and Meta-Analysis

Assefa Sisay, Zelalem Asmare, Ermias Getachew, Birhanu Kassanew, Ephrem Tamrat, Yalewayker Gashaw, Melese Abate Reta

Background: Biofilms help Pseudomonas aeruginosa adhere to surfaces and form an extracellular polymeric matrix. P. aeruginosa infections are increasingly difficult to treat due to biofilm formation. This study seeks to ascertain the overall prevalence of biofilm-forming P. aeruginosa clinical isolates in Africa. Methods: All studies published from January 1, 2010, to December 30, 2024, were systematically obtained from electronic databases, including PubMed, ScienceDirect, and Scopus, as well as via the Google Scho …

17.08.2026journal-article

Journal of Clinical Medicine

Theranostics in Radiation Medicine: Integrating Radiopharmaceutical Therapy and External-Beam Radiotherapy

Senthamizhchelvan Srinivasan, Joseph A. Moore, Sarah Han-Oh

Theranostics has transformed nuclear medicine from an imaging-focused discipline into a data-rich radiation medicine platform in which target expression, pharmacokinetics, tumor dose, and response can be measured in the same patient. This critical narrative review evaluates patient-specific integration of radiopharmaceutical therapy (RPT) with external-beam radiotherapy (EBRT), with emphasis on quantitative imaging, absorbed-dose estimation, spatial registration, biological interpretation, adaptation thresholds, an …