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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Frontiers in Reproductive Health

BRIDGES: a patient-centered, community-informed HIV doula program that supports infant feeding choice among Hispanic and Caribbean families: a study protocol

Rachel Mpanu-Mpanu, Melanie Francis, Kassandra N. Garcia, Lunthita M. Duthely

Background In 2023, U.S. Perinatal HIV Guidelines shifted from recommending exclusive formula feeding to endorsing shared decision-making for infant feeding among pregnant and postpartum persons with HIV (PPWH) on antiretroviral therapy (ART) with sustained viral suppression. While the risk of HIV transmission through breastfeeding is small (< 1%) with sustained viral suppression, adherence protocols are complex and clinical support infrastructure remains underdeveloped. Doula care has demonstrated benefits for …

28.08.2026journal-article

Frontiers in Medicine

Future work self-salience and perceived professional benefits among nursing interns in China: the indirect roles of clinical belongingness and deep acting in a cross-sectional structural equation modeling study

Ruoyu Du, Yamei Zhang, Qiuyue Cui, Ying Zhong, Man Zhang, Yuan Ge

Objective This study examined whether future work self-salience was associated with perceived professional benefits among nursing interns and whether clinical belongingness and deep acting were involved as independent and serial mediators in this association. Methods A cross-sectional online survey was conducted among 641 nursing interns recruited from six higher education institutions in Guangxi, China (March–April 2026). Measures included future work self-salience (4 items), clinical belongingness (17 items), dee …

28.08.2026journal-article

Frontiers in Public Health

National trends in neonatal and under-five mortality in Saudi Arabia (2018–2023): a descriptive ecological analysis using WHO Global Health Observatory data

Eman M. Alanazi, Yara Alkhalid, Ahmed Alqheedan, Saleh Alzughaibi

Background Neonatal mortality rate (NMR) and under-five mortality rate (U5MR) are core child-survival indicators and are influenced by, though not a direct measure of, the quality of maternal and newborn care. Saudi Arabia has achieved substantial reductions in both indicators over recent decades; however, year-to-year dynamics during the period of Vision 2030 health reforms remain incompletely described using standardized, internationally comparable data. Objective To describe annual trends in NMR and U5MR in Saud …

28.08.2026journal-article

Frontiers in Cardiovascular Medicine

Heart failure and suicide mortality and suicide attempts: a systematic review and meta-analysis of cohort studies

Ting Meng, Rui Zhang, Qiufeng Li, Yaqin Li, Hui Zhou, Jian Zhang

Objective This systematic review and meta-analysis aimed to synthesize longitudinal observational evidence on the associations of heart failure (HF) with suicide mortality and suicide attempts. Methods PubMed, Embase, and the Cochrane Library were systematically searched from inception to April 11, 2026, to identify cohort studies evaluating suicide mortality or suicide attempts among individuals with HF. Study quality was assessed using the Newcastle-Ottawa Scale. Because suicide mortality and suicide attempts are …

28.08.2026journal-article

Frontiers in Public Health

Public–private partnerships for UAV-assisted emergency medical services in aging communities: an evolutionary game approach

Jingling Zhong, Yali Gao

Objective To analyze the current “market failure” in the large-scale deployment of UAV-assisted automated external defibrillator (AED) delivery networks for aging communities, and to explore innovative “Public–Private Partnership” (PPP) business models to overcome the “cold-start” institutional deadlock. Methods This study introduces a three-party evolutionary game model comprising community representatives, medical institutions, and UAV operators. By integrating principles of “health economics,” we simulated the i …

28.08.2026journal-article

JHN: Journal of Health and Nursing

PROSEDUR TEKNIK PEMERIKSAAN RADIOGRAFI VERTEBRAE CERVICAL PADA KLINIS CERVICAL SYNDROME DI INSTALASI RADIOLOGI RSUD SLEMAN

Mirnawati Mirnawati, Ildsa Maulidya Mar’atus Nashoka, Syahara Listyawan

Cervical syndrome is a disorder of the cervical vertebrae that can cause neck pain and activity limitations. Cervical spine radiography serves as a supporting examination for establishing a diagnosis. According to Lampignano and Kendrick (2018), cervical spine radiographic examinations include AP axial, lateral, and oblique projections. Oblique projections can be performed using RPO/LPO or RAO/LAO positions. However, at the Radiology Department of Sleman Regional General Hospital (RSUD Sleman), the axial, lateral, …

28.08.2026journal-article

BMC Public Health

Adverse childhood experiences and labour market inactivity among young women: a population-based study

Harpa S. Eyjólfsdóttir, Marín Dögg Bjarnadóttir, Hilda Björk Daníelsdóttir, Arna Hauksdottir, Edda Bjork Thordardottir, Thor Aspelund, Unnur A. Valdimarsdóttir

Abstract Background Young people not in employment, education, or training (NEET) are a major concern presenting extensive societal and personal costs. Adverse childhood experiences (ACEs) can have longstanding harmful effects on health, education and employment participation. This study examined if ACEs are associated with NEET status among young Icelandic women, and whether perceived coping ability and social support moderate this relationship. Methods Using data from 6 101 women aged 18–29 in the Stress-And-Gene …

28.08.2026journal-article

British Journal of Haematology

First‐line hetrombopag combined with immunosuppressive therapy for paediatric severe aplastic anaemia: A prospective randomized controlled trial

Lingling Fu, Bixi Yang, Ruixin Wang, Hongmin Li, Hui Chen, Jie Ma

Summary Although the thrombopoietin receptor agonist hetrombopag (HPAG) improves response in adults with severe aplastic anaemia (SAA), its efficacy in paediatric patients remains unclear. In this single‐centre, prospective trial, 54 children with newly diagnosed SAA were randomized to receive standard immunosuppressive therapy (IST) alone ( n = 27) or combined with HPAG (IST+HPAG, n = 27). The primary end‐point was complete response (CR) rate (CRR) at 6 months. Baseline characteristics were balanced. At 6 months, …

28.08.2026journal-article

Belitung Nursing Journal

Negotiating faith in a hospital bed: A qualitative exploration of barriers to prayer (Solah) among hospitalised Muslim orthopaedic patients in Malaysia

Mohd Ariff Sharifudin, Yuzana Mohd Yusop, Mai Nurul Ashikin Taib, Mohd Fitri Omar, Al Hafiz Ibrahim, Anas Mohd Yunus

Background: For Muslim patients, performing the five daily prayers (Solah) is a non-negotiable pillar of faith and a vital source of spiritual solace during illness. In Malaysia, the Ibadah-Friendly Hospital (IFH) framework was established to support this need within holistic care. However, adherence remains low, particularly among patients with physical limitations, such as orthopaedic conditions, suggesting a significant gap between policy and lived experience. Objective: This study aimed to explore in-depth the …

28.08.2026journal-article

World Journal of Radiology

Imaging-guided adaptive radiation therapy in limited-stage small cell lung cancer: Current evidence and clinical perspectives

Omer Sager

Small cell lung cancer (SCLC) remains among the most aggressive thoracic malignancies and continues to present major therapeutic challenges despite advances in multimodality treatment. Limited-stage SCLC (LS-SCLC), representing approximately one-third of cases, is conventionally managed with concurrent chemoradiotherapy delivered with curative intent. Radiation therapy (RT) is central to treatment; however, rapid treatment related anatomical and volumetric changes may alter target geometry and reduce the accuracy o …

28.08.2026journal-article

Frontiers in Public Health

Sport-specific injury profiles and associated factors in elite wrestlers and judokas

Yunus Sadır, Faik Öz, Suzan Dal, Selin Biçer Baikoğlu, İrfan Kara, İzzet Karakulak, Hakan Bilgen, Yusuf Kurt, Cüneyt Şensoy, Osman Imamoğlu, Serdar Koç

Background Wrestling and judo involve repeated physical contact and substantial musculoskeletal demands. Although the two sports share structural similarities, differences in sport-specific demands may be associated with distinct injury characteristics. This study compared self-reported injury profiles between elite wrestlers and judokas and examined factors associated with reporting multiple injury episodes. Methods This cross-sectional comparative study included 289 Turkish National Team athletes, comprising 143 …

28.08.2026journal-article

Frontiers in Digital Health

An LLM-supported just-in-time adaptive intervention delivered by a socially assistive robot for cognitive training in mild cognitive impairment: study protocol for an assessor-blinded randomized controlled trial

Jingzheng Yan, Yahui Cheng, Yaning Wang, Yingjuan Cao

Background Mild cognitive impairment (MCI) is a clinically important stage at which non-pharmacological interventions may help preserve cognitive function and daily functioning. Existing digital cognitive training programs are often limited by static task progression, declining engagement, and insufficient responsiveness to moment-to-moment cognitive and emotional states. Objective This study protocol describes a single-center, parallel-group, assessor-blinded randomized controlled trial evaluating an adaptive cogn …

28.08.2026journal-article

Frontiers in Education

Comprehensively understanding K-12 teachers’ occupational health: a convergent mixed-methods exploration of stress and wellbeing

Cynthia A. Wiltshire, Christopher J. McCarthy, Caroline Weppner, Richard G. Lambert, Yijie Tian

Stress has detrimental impacts on K-12 teachers’ occupational health, yet there is no consensus on how best to define and measure it. As such, the present study implemented quantitative and qualitative methodologies, including a physiological measure of stress, to comprehensively assess and understand teacher stress in one independent school district in the southern United States. Forty-four public school teachers participated by completing self-reported measures of stress and occupational health, providing a hair …

28.08.2026journal-article

Communications Medicine

Venular-centered thrombo-inflammation drives microvascular failure after arterial recanalization in acute mesenteric ischemia

Déborah François, Lambert Kernanet, Melinda Bajul, Abigail Brami, Véronique Arocas, Marie-Christine Bouton, Dominique Cazals-Hatem, Kevin Guedj, Benoit Ho-Tin-Noé, Olivier Corcos, Yacine Boulaftali, Alexandre Nuzzo

Abstract Background Acute mesenteric ischemia (AMI) remains associated with high mortality despite prompt revascularization, suggesting that downstream ischemia–reperfusion injury contributes to poor outcomes. However, the microvascular mechanisms underlying this process are not entirely defined. Methods We analyzed admission blood samples from patients with arterial AMI and non-ischemic controls enrolled in the SURVIBIO diagnostic study (NCT03518099). We also investigated thrombo-inflammatory responses in a murine …

28.08.2026journal-article

Advances in Laboratory Medicine / Avances en Medicina de Laboratorio

Prediction of coagulation factor inhibitor levels using Random Forest model based on the activated partial thromboplastin time (aPTT) mixing study: model development and prototype application

Chulalak Kongkan, Pakaporn Detsuk, Sarawin Hnusing, Yanakamin Phomcharoen, Chadaporn Nokkong, Chaowanee Wangchauy, Saristha Buathong, Tipparat Penglong, Peempol Chokchaipermpoonphol

Abstract Objectives This study aimed to develop a machine learning approach to predict factor VIII inhibitor titers from activated partial thromboplastin time (aPTT) mixing study data. Methods Records of 173 patients who underwent factor VIII inhibitor testing at Songklanagarind Hospital from January 2023 to December 2025 were retrospectively analyzed. Predictor variables included mixing aPTT, age, and sex, with Bethesda assay inhibitor titer as the outcome. A two-stage hurdle Random Forest model was developed, con …

28.08.2026journal-article

Borneo Nursing Journal (BNJ)

Pengaruh Pemberian Edukasi Terhadap Kesiapan Orang Tua Dalam Mendeteksi Diabetes Melitus Pada Anak Di Wilayah Puskesmas Kuin Raya

Linda Lestariani, Cynthia Eka Fayuning Tjomiadi, Ahmad Syahlani, Rian Tasalim

Diabetes Melitus (DM) pada anak merupakan penyakit kronis yang terus meningkat prevalensinya.Peran orang tua sangat penting dalam mengenali tanda dan gejala awal, namun kesiapan orang tuadalam melakukan deteksi dini masih belum optimal, diperlukan upaya peningkatan pengetahuan dankesiapan melalui pemberian edukasi kesehatan. Penelitian ini bertujuan untuk mengetahui pengaruhpemberian edukasi terhadap kesiapan orang tua dalam mendeteksi diabetes melitus pada anak.Penelitian ini menggunakan pendekatan kuantitatif den …

28.08.2026journal-article

Scientific Reports

Enhancing clinical reasoning and diagnostic precision through scaling laws and multi-stage supervised fine-tuning in open-weight medical large language models

Lukasz Pawlik, Stanislaw Deniziak

Abstract The emergence of large language models offers unprecedented opportunities to transform clinical workflows. However, reliance on proprietary closed-source models poses significant risks to data privacy, institutional autonomy, and reasoning transparency. This study investigates the optimization of open-weight architectures, specifically the Llama-3.1-8B and Qwen2.5-14B-Instruct families, to function as specialized diagnostic tools rather than general-purpose conversational agents. Utilizing the MedQA USMLE- …

28.08.2026journal-article

Health Research Journal of Indonesia

Hubungan Pola Asuh Orang Tua dengan Perilaku Picky Eating pada Anak Usia Prasekolah di TK Islam Bakti Kauman Batang

Hesti Fathan Nurfais Fauziah, Fatikhah, Penthatasya, Yulia Ardiyanti

Latar Belakang: Picky eating merupakan salah satu masalah perilaku makan yang sering dijumpai pada anak usia prasekolah dan berkaitan dengan kecukupan asupan gizi serta pertumbuhan anak. Pola asuh orang tua merupakan aspek pengasuhan yang sering dikaji dalam hubungannya dengan perilaku makan anak, namun hasil penelitian sebelumnya masih menunjukkan temuan yang belum konsisten. Tujuan: Menganalisis hubungan pola asuh orang tua dengan perilaku picky eating pada anak usia prasekolah di TK Islam Bakti Kauman Batang. Me …

28.08.2026journal-article

EPMA Journal

Evidence-based recommendations for advancing the chronic pelvic pain syndrome management by the paradigm change from reactive symptom suppression to proactive 3PM-guided patient-centered care

Ousman Bajinka, Lamarana Jallow, Na Li, Christian Kuhn, Walther Kuhn, Ivana Stetkarova, Olga Golubnitschaja, Xianquan Zhan

Abstract Chronic pelvic pain syndrome (CPPS) encompasses a heterogeneous group of debilitating conditions including interstitial cystitis/bladder pain syndrome (IC/BPS), chronic abacterial prostatitis, endometriosis, and pelvic congestion syndrome, among others. Despite advances in symptomatic management, CPPS remains challenging due to its multifactorial etiology, complex phenotypes, and poor response to conventional reactive treatments. On the other hand, sympathetic overdrive phenotype (SOP) carriers frequently …

28.08.2026journal-article

Journal of Public Budgeting, Accounting & Financial Management

Local self-government audit reporting in selected Balkan countries: a comparative content analysis of supreme audit institutions' reports

Ivan Dionisijev, Zorica Bozhinovska Lazarevska, Todor Tocev, Bojan Malchev

Purpose This study evaluates the transparency and reporting practices of local self-government (LSG) audit reporting across four Supreme Audit Institutions (SAIs), North Macedonia, Montenegro, Croatia and Slovenia, over the period 2015–2024. It examines how SAIs communicate municipal audit results, the extent to which reporting practices align with internationally recognized accountability principles and how differences in institutional contexts are associated with variation in reporting patterns. Design/methodolog …

28.08.2026journal-article

Frontiers in Medicine

Precise diagnosis and management of non-traumatic radial nerve palsy attributed to multiple rare etiologies: case study and literature review

Yanchen Dong, Nanfei Zheng, Hongyue Men, Chen Xie

While non-traumatic radial nerve palsy is relatively rare, cases triggered by a single etiological factor pose minimal diagnostic and therapeutic challenges. However, for radial nerve palsy driven by multiple factors, the overlapping or masking effects of symptoms and signs from distinct etiologies complicate accurate diagnosis and optimal management. This complexity is further amplified when all contributing factors are rare, presenting a more formidable challenge to precise diagnosis and treatment selection. We p …

28.08.2026journal-article

Journal of Complementary and Integrative Medicine

Evaluation of anti-osteoarthritic activity of hydroalcoholic extract of Moringa oleifera by using papain-inducing model in experimental animals

Vaibhav Sangameshwar Gavane, Snehal Ambadas Gojare, Deepti Dinesh Bandawane

Abstract Background The anti-inflammatory, anti-arthritic, and antioxidant qualities of Moringa oleifera have long been used to treat inflammation and various types of arthritis. Objectives To evaluate the hydroalcoholic extract of Moringa oleifera pods in a papain-induced animal model. Materials and methods Hydroalcoholic extraction was used to obtain the hydroalcoholic extract of Moringa oleifera (HEMO), and its phytochemical constituents were examined. In Wistar rats, osteoarthritis was induced by intra-articula …

28.08.2026journal-article

Belitung Nursing Journal

Family-centered early intervention: A concept analysis to guide pediatric and community nursing practice

Mardiyanti Mardiyanti, Yeni Rustina, Nani Nurhaeni, Nur Agustini

Background: Family-Centered Early Intervention (FCEI) is increasingly recognized as a framework for promoting child development and family empowerment. However, its application in nursing practice may be limited by the lack of a clear distinction between FCEI, Family-Centered Care (FCC), and Patient- and Family-Centered Care (PFCC). Objective: To clarify the concept of FCEI and distinguish it from FCC and PFCC by identifying its defining attributes, antecedents, consequences, and empirical referents. Methods: Walke …

28.08.2026journal-article

BMC Sports Science, Medicine and Rehabilitation

Optimizing exercise for breast cancer survivors: a randomized controlled trial of daily individualization of high-intensity online concurrent training guided by autonomic modulation

Ana Myriam Lavín-Pérez, Daniel Collado-Mateo, Inés Nieto, Xián Mayo, Carmen Hinojo González, Ana de Juan Ferré, Gary Liguori, Alfonso Jiménez

Abstract Background Breast cancer and its treatments cause physical and physiological side effects that exercise can mitigate. However, there is little evidence on the effects and feasibility of high-intensity remote supervised training. In addition, there is no evidence of the effect of individualizing intensity prescription based on autonomic control in this population. Thus, this study aimed to compare the effects of two concurrent online exercise programs, pre-planned intensity prescription (PPI) and intensity …