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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
26.08.2026journal-article

Frontiers in Sports and Active Living

Can aerobic exercise really improve factors related to decision-making capacity in aging? What has been measured, what has been assumed, and what needs to change

Jonathan A. Cortés Silva, Christina A. Davis, Diego Lievano Parra, Valeria V. González

As populations age globally, cognitive decline has become one of the most pressing health challenges of our century. Early cognitive decline usually manifests as problems related to decision-making processes. In this context, aerobic exercise has emerged as a promising strategy for preserving and improving brain health. However, a critical question remains underexplored: whether improvements in executive function (EF) tasks truly reflect enhanced decision-making capacity, or whether they index more circumscribed ch …

26.08.2026journal-article

Psikoloji Çalışmaları / Studies in Psychology

Psychological Symptoms in Caregivers of Individuals Diagnosed with Dementia in Turkey: A Conservation of Resources Perspective

Elçin Yorulmaz, Gülay Dirik, Simge Balaban

Dementia is a disorder that is expected to increase in prevalence over the years and affects the daily lives of individuals. Because of its cognitive, emotional, and behavioral effects, dementia can impact a person's daily life and create a need for care. Since providing care involves many struggles, caregivers may experience numerous psychological symptoms. The purpose of the current study was to investigate the factors correlated with psychological symptoms experienced by caregivers of individuals diagnosed with …

26.08.2026journal-article

Frontiers in Immunology

Effect of blueberry consumption on regulatory lymphocyte phenotypes and NK cell functional activity in middle-aged and older adults with overweight or obesity: a randomized controlled trial

Abril I. Sánchez-Rosales, Sujatha Rajaram, Nadia Nemeh-Saad, Rawiwan Sirirat, Jacqueline Coats, Alan Cupino, Juli J. Unternaehrer, Joan Sabaté

Background Age-related changes in immune regulation and innate immune responses may be influenced by chronic low-grade inflammation associated with adiposity. Blueberries, rich in anthocyanins, may modulate inflammatory responses through effects on oxidative stress and phenolic metabolites; however, evidence from randomized controlled trials (RCTs) remains limited. We evaluated whether daily blueberry consumption modifies select cellular immune markers and inflammatory biomarkers in adults with overweight or obesit …

26.08.2026journal-article

Aging Cell

Associations Between Accelerometer‐Assessed Sleep Patterns, Proteomic Signatures, and Hallmarks of Aging in Adulthood

Ruiyi Liu, Jingsong Luo, Yangchang Zhang, Furong Wang, Jing Xu, Wangnan Cao, Shengzhi Sun

ABSTRACT The associations between objectively measured sleep patterns, the hallmarks of aging, and their shared proteomic signatures remain poorly understood. In this study, we utilized wrist‐worn accelerometer data, plasma proteomic profiles, and health records from the UK Biobank to examine the associations between six defined sleep patterns and nine established hallmarks of aging. We further identified proteins jointly associated with both sleep patterns and aging hallmarks. Longer total sleep duration, greater …

26.08.2026journal-article

Frontiers in Aging Neuroscience

Modulation of fronto-parietal and autonomic activity underpins preserved working memory in middle-aged adults

Myriam Cayre, Laure Spieser, Anaïs Guille, Nathalie Baril, Arnaud Weill, Caroline Chambon

Background Cognitive aging is a heterogeneous process, often diverging from chronological age. However, it remains unclear when early signs of cognitive decline emerge and which neurophysiological markers distinguish age-related cognitive alteration from preserved performances. This study aimed to identify early indicators of cognitive versus chronological aging. Methods In a group of middle-aged adults (MA, n = 60), we distinguished high performers (MA_HP; n = 24; mean age ± SEM 54.2 ± 0.6-year-old) from low perfo …

26.08.2026journal-article

Journal of Medical Internet Research

Naturalistic Online Language as a Marker of Depression in Midlife and Older Adults: Computational Text Analysis of Bluesky and Reddit Posts

Lauren Rutter, Andy Edinger, Marijn ten Thij, Lorenzo Lorenzo-Luaces, Danny Valdez, Johan Bollen

Abstract Background Social media use among older adults continues to grow. Many people use social media to establish meaningful social ties and discuss their mental health. Depression in midlife and older adults is a critical public health concern, yet scalable, sensitive methods for early detection remain limited. Natural language processing offers new opportunities to examine sentiment and mental health through online language in typically understudied populations. Objective This study examined whether sentiment …

26.08.2026journal-article

Revista da Associação Brasileira de Pesquisadores/as Negros/as (ABPN)

RACISMO, ESTEREÓTIPOS RACIAIS E IMPLICAÇÕES NAS TRAJETÓRIAS PROFISSIONAIS DE PESSOAS NEGRAS

Sabrina Prado Anjos, Quézia Costa Dias, Emerson Douglas Dos Santos Martins

Este artigo mapeia e sistematiza produções científicas sobre os efeitos do racismo e dos estereótipos raciais nas trajetórias de carreira de pessoas negras. Com base na Teoria Crítica da Raça e na Psicologia do Trabalhar, analisou 33 estudos publicados entre 2020 e 2025, majoritariamente qualitativos, oriundos sobretudo dos Estados Unidos e do Brasil. A análise temática identificou obstáculos anteriores ao ingresso no mercado, relacionados ao acesso e à escolha profissional, e desafios posteriores à inserção, como …

26.08.2026journal-article

Campbell Systematic Reviews: Better Evidence for a Better World

Protocol: Emerging Roles and Care Impacts of Geriatric Pharmacists in Outpatient Multidisciplinary Frailty and Geriatric Syndrome Management: A Systematic Review

Ravi Shankar, Fiona Devi, Xu Qian, Amaevia Lim

This is the protocol for a Campbell systematic review. The objectives are as follows: (1) to summarize the current literature on the roles, responsibilities, and care activities of geriatric pharmacists in outpatient multidisciplinary management of frailty and geriatric syndromes; (2) to evaluate the impact of geriatric pharmacist involvement on medication-related outcomes, patient health outcomes, quality of life, and healthcare utilization; (3) to characterize the patient populations, healthcare settings, and mul …

26.08.2026journal-article

Discover Health Systems

A mixed methods exploration of mental health pathways and treatment as usual for young people experiencing depression in the United Kingdom

Siobhan B. Mitchell, Vashti Berry, Juliette Westbrook, Emma Grace Carey, Alice Wickersham, Alice Garrood, Rachel Hayes, Julieta Galante, Husna Hassan Basri, Kristin Liabo, Tamsin Ford

Abstract Epidemiological data indicate that the prevalence of depression among young people (YP) is increasing. Although evidence-based interventions are effective for many, 20 to 40% fail, and relapse is common. This study focused on second-line treatments. Modifying psychological processes that predispose individuals to treatment failure or relapse necessitates the development of interventions, but their evaluation depends on a clear understanding of current practice to enable meaningful comparison and assessment …

26.08.2026journal-article

Journal of Clinical Medicine

Cardio-Oncology in Older Adults: Evidence Gaps, Geriatric Considerations, and Future Directions

Vasiliki Katsi, Lefki Nikolopoulou, Christos Fragoulis, Vasilios Kordalis, Konstantinos Tsioufis, Konstantinos Toutouzas

Cardio-oncology has emerged as a critical discipline addressing cardiovascular toxicities from cancer therapies, yet substantial evidence gaps persist for elderly patients, who represent over 60% of new cancer diagnoses. This narrative review synthesizes the current literature on cardio-oncology challenges in older adults (≥65 years), highlighting underrepresentation in clinical trials, compounded risks from frailty, multimorbidity, and polypharmacy, and the paucity of geriatric-specific guidelines. Older adults ex …

26.08.2026journal-article

Aging Cell

Timing‐Dependent Clearance of p16‐Positive Cells Mitigates Radiation‐Induced Accelerated Aging

Karla Valdivieso, Melanie Weigand, Daniela G. Costa, Gung Lee, Nick Pirius, Helene Martini, Shivangi Oberai, Christina Inman, Yi Zhu, Thomas von Zglinicki, Sundeep Khosla, Nathan LeBrasseur, João F. Passos, Tamara Tchkonia, James L. Kirkland, Diana Jurk

ABSTRACT Genotoxic stress induced by cancer therapies is increasingly recognized as a driver of accelerated aging in long‐term cancer survivors, yet the mechanisms responsible for the emergence of age‐related dysfunction months to years after treatment remain poorly understood. Here, we use sublethal whole‐body irradiation as a model of systemic genotoxic stress to test whether senescent cells contribute to the progression of post‐therapy age‐related dysfunction and whether the benefits of senescent cell clearance …

26.08.2026journal-article

Cytotherapy and Longevity

Effects of Antidiabetic Drugs on Longevity and Healthspan: Evidence and Controversies From Glucose-Lowering Therapy to Anti-Aging Intervention

Xuancheng Zhou, Xinguo Hou

Diabetes provides a clinically visible model of accelerated biological aging. Sustained hyperglycemia, insulin resistance, chronic low-grade inflammation, mitochondrial stress, and endothelial injury converge to increase the burden of cardiovascular disease, chronic kidney disease, neurodegeneration, sarcopenia, and frailty, thereby compressing both survival time and years lived with preserved function. For this reason, evaluation of glucose-lowering drugs can no longer be restricted to HbA1c reduction alone. Morta …

26.08.2026journal-article

Journal of Population Ageing

Association of Parental and Own Educational Attainment Versus Intergenerational Mobility with Cognitive Performance in Brazilian Older Adults

Lidia Lack, Natalia Gomes Goncalves

Abstract Background Education is associated with better cognitive performance in later-life. However, the role of intergenerational educational mobility is less studied. We investigated the associations of participants' own educational attainment, the educational attainment of their parents, and educational mobility, with cognitive performance among Brazilian older adults. Methods We used data from the Brazilian Longitudinal Study of Aging. Cognitive assessment used a global cognitive z-score derived from memory, t …

26.08.2026journal-article

Academic Journal of Health Sciences

Workplace healthy-aging promotion in midlife: mental health and Mediterranean-diet gains from a pilot intervention

Asunción María Fernández-Rodríguez, Juan Carlos Rueda-Garrido, Oscar Arrogante, Diana Jiménez-Rodríguez

Introduction: Population aging is reshaping occupational health, as midlife mental health and lifestyle behaviors influence later-life morbidity. This uncontrolled before-after pilot study evaluated whether a multidisciplinary healthy-aging promotion program (nutrition, physical activity, mental health) was associated with changes in physical and mental health among workers from the Spanish chemical industry. Methods: A pilot before-after longitudinal study without a control group in 18 of 29 enrolled workers (62% …

26.08.2026journal-article

npj Aging

Sex differences in the prevalence and incidence of motoric cognitive risk syndrome: a systematic review and meta-analysis

Siyi Sun, Jingru Zhu, Qing Hu, Xiaoke Zhong, Changhao Jiang

Abstract Motoric cognitive risk (MCR) syndrome, a pre-dementia construct combining subjective cognitive complaints with slow gait speed, shows inconsistent sex differences in prevalence and incidence across studies, possibly reflecting differences in gait speed diagnostic criteria rather than biological differences. We conducted a systematic review and meta-analysis (PRISMA 2020; PubMed, Web of Science, Embase, and Scopus; January 2013–March 2026), pooling sex-difference risk ratios (RR, male vs. female) with rando …

26.08.2026journal-article

Working with Older People

Matching coordination to complexity: integrated care for older adults with multiple needs

Hasan Tutar, Dalia Streimikiene

Purpose This study aims to conduct a systematic review and meta-analysis of care coordination interventions for older adults with intersecting physical, cognitive and social needs, addressing a gap in the fragmented evidence base and the practical challenge of matching coordination to complexity. Design/methodology/approach Following PRISMA guidelines, ten controlled studies and three published syntheses (2015–2025) were identified; four randomised trials permitted back-calculation of standardised effect sizes for …

26.08.2026journal-article

REVISTA DE ESTUDOS INTERDISCIPLINARES

O PERFIL ÉTNICO-RACIAL DA CÂMARA DE VEREADORES DO MUNICÍPIO DE ARAPIRACA E A REPRESENTAÇÃO DE NÃO BRANCOS

Karolyne Roberto Santos Pereira, Tiago Soares Vicente

The present study examines Black political representation within the municipal Legislative Branch of Arapiraca, Alagoas. Its primary objective is to determine whether Black and Mixed-race (pardo) individuals are underrepresented in the City Council relative to the ethnic-racial composition of the local population, or if such representation is proportional. The methodology employs a mixed-methods approach—both quantitative and qualitative—with a descriptive and analytical framework. The research is based on secondar …

26.08.2026journal-article

Scientific Journal of National Pedagogical Dragomanov University Series 15 Scientific and pedagogical problems of physical culture (physical culture and sports)

Pedagogical mechanisms for fostering moral and volitional resilience in older adolescents through mass sports activities

Olena Lytovchenko, T. V. Polishchuk, A. M. Lynnyk

The article explores the potential of mass sports activities for fostering moral and volitional resilience in older adolescents. It is substantiated that the educational potential of mass sports activities is realized through the voluntary acceptance and fair observance of rules; participants’ acquisition of experience in overcoming physical, emotional, and communication-related difficulties; experiencing success and failure and developing a constructive attitude towards them; taking responsibility for one’s person …

26.08.2026journal-article

NCVS Insights

Is It Self-Awareness or Is It Sensory Feedback? Difficulties in Self-Perception of One's Own Voice in People with Parkinson's Disease

Francisco Contreras-Ruston

Parkinson’s disease (PD) is widely known for its impact on movement: tremor, rigidity, and slowed gait. Less visible, but equally disabling, are the changes it imposes on the voice (Duffy, 2020). Most people with PD (PwPD) develop hypokinetic dysarthria, the first symptom of which is usually reduced vocal intensity (a hallmark of hypophonia), along with a diminished pitch range and reduced articulatory precision (Duffy, 2020). These changes compromise communication quality and, consequently, social participation an …

26.08.2026journal-article

Journal of General Education and Humanities

Existence of The Menyilaq Tradition Among the Sasak People in the Face of The Advance of Modern Information Technology

Suhadah Suhadah, Fathurrijal Fathurrijal, Nur Ilham, Naoval Rahman, Baiq Ida Astini, Kadri Kadri

This study aims to examine the existence of the menyilaq tradition among the Sasak people, identify the dynamics of change resulting from the development of modern information technology, and uncover the adaptation and preservation strategies used to maintain cultural and social values, as well as local wisdom, in the digital age. The study employs a qualitative descriptive approach, with research sites in Mataram City, West Lombok Regency, and North Lombok Regency that represent urban, suburban, and indigenous com …

26.08.2026journal-article

Frontiers in Aging

Repurposing MK0873 as a non-covalent hTERT-Targeting compound: a proof of concept study

Maham Ansari, Abdul Wali, Mohhamed Rasul, Kristina Gemzell Danielsson, Twana Alkasalias, Muhammad Mushtaq

Telomerase is a key regulator of both cellular immortality and aging, making it an attractive target for cancer therapy and age associated pathologies. Its clinical exploitation has been limited by structural complexity and challenges in achieving specificity. Recent structural insights into human telomerase reverse transcriptase (hTERT) have enabled the identification of selective inhibitors. Here, we repurposed MK0873, a PDE4 inhibitor previously evaluated in Phase II clinical trials for rheumatoid arthritis and …

26.08.2026journal-article

WORLD JOURNAL OF INNOVATION AND MODERN TECHNOLOGY

Environmental Education Programs for Discouraging Destruction of Aquatic Lives Among Kalabari People in Rivers State

Ijeoma Roseline John

This study examined environmental education programmes for discouraging destruction of aquatic lives among kalabari people in Rivers State, Nigeria. Three research objectives, and three null hypotheses were used for the study. The study adopted a descriptive survey research design. The population of the study consists of 522 community inhabitants, comprising 326 male and 196 female fisher folks that are members of registered fishing folk’s association in the study area. The entire population was used for the study …

26.08.2026journal-article

Addiction

Exploring the influence of user‐generated content on alcohol‐related attitudes and behaviours among young people: A systematic review

Alessandro Crocetti, Nichole Lister, Jennifer Browne, Florentine Martino, Kathryn Backholer, Benjamin Riordan, Peter Miller, Matthew Dunn

Abstract Background and aims Alcohol‐related content on social media, particularly user‐generated content (UGC), is an increasingly normal feature of young people's digital lives and has been linked to increased alcohol use; however, a critical gap remains in understanding how different subgroups of young people are exposed to and engage with such content, and how this may be associated with their alcohol‐related attitudes and behaviours. This systematic review aimed to synthesise evidence on the association betwee …