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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
31.08.2026journal-article

Frontiers in Oncology

Immune checkpoint inhibitor-related intestinal pseudo-obstruction and multisystem immune-related adverse events in a post-gastrectomy patient: a case report and literature review

Zhening Liu, Chao Wang, Yulei Shen, Yanfen Shi, Jianghui Duan, Huijing Dong, Yangbo Xu, Yumin Zheng, Huijuan Cui

Background Immune checkpoint inhibitors are increasingly recognized to be associated with multisystem immune-related adverse events. Cases presenting predominantly with intestinal pseudo-obstruction (IPO) are rare, prone to misdiagnosis, and may indicate broader immune-mediated toxicity. Case presentation We report the case of a patient with gastric cancer who developed intestinal pseudo-obstruction and multisystem immune toxicity during postoperative adjuvant chemotherapy plus nivolumab. The patient’s symptoms imp …

31.08.2026journal-article

Frontiers in Public Health

Effects of different types of mind–body exercises on depressive symptoms in older adults: a systematic review and network meta-analysis

Zaiwen Wang, Ying Zhu, Wenqian Li, Pengfei Wang, Yue Liu, Yu Yin, Chengjun Li, Qian Qin, Hongyu Wang

Background Depressive symptoms in older adults (≥60 years) have a global prevalence of 10–20%, linked to physiological decline, neurotransmitter imbalances and other factors, burdening families and healthcare resources. Existing treatments (pharmacological and non-pharmacological) have limitations, while mind–body exercises hold intervention potential due to their “mind–body linkage” trait—yet comparative effectiveness studies across different types are lacking. Methods Systematic searches were conducted across fou …

31.08.2026journal-article

Frontiers in Medicine

Shock index-modified qSOFA improves mortality risk stratification in patients with sepsis beyond conventional qSOFA

Yue Zhou, Yue-feng He, Jian Rao, Jin-long Wang

Background The quick Sequential Organ Failure Assessment (qSOFA) score does not incorporate hemodynamic perfusion parameters, which may limit its ability to identify septic patients with early circulatory compromise before the development of overt hypotension. This study aimed to evaluate a modified score incorporating the shock index (SI), termed SI-qSOFA, and to determine whether it could improve identification of high-risk patients classified as low-risk by conventional qSOFA. Methods A retrospective cohort stud …

31.08.2026journal-article

Clinical Practice in Pediatric Psychology

Bolus Fading to Prepare a Tube-Dependent Child for Video Fluoroscopic Swallow Study: A Case Report

Ashley S. Andersen-Weber, Meeta R. Patel

Children with prematurity and complex medical histories are at increased risk for tube dependence, feeding aversion, and aspiration, which can interfere with completing a video fluoroscopic swallow study (VFSS) making it challenging to target broader feeding goals. This case report describes a bolus fading intervention designed to establish consistent oral intake and prepare a tube-dependent child for VFSS. An 18-month-old child born at 26 weeks’ gestation with severe bronchopulmonary dysplasia, a prior failed VFSS …

31.08.2026journal-article

Fabad Journal of Pharmaceutical Sciences

Design, Optimization And Performance Profiling Of Flexible Nano-vesicular Ciprofloxacin Gel: A Targeted Therapy For Ocular Bacterial Keratitis

Satyam Khajuria, Pritpal Kaur Malhi, Ramandeep S Narang, Karanpreet Kaur, Jasjeet Kaur Narang

Bacterial keratitis (BK) constitutes a severe eye infection capable of causing substantial vision loss, leading to ulceration and Inflammation. BK is major cause of corneal blindness in developing countries, faces challenges from the eye's protective structures, limiting drug bioavailability from conventional forms. To address the limitations of conventional dosage forms and to enhance drug efficacy, ciprofloxacin loaded nano-vesicular carriers were developed and then integrated into an optimized agent to induce ge …

31.08.2026journal-article

Games

Patient-Level Costing, Strategic Reimbursement, and Budget-Constrained Coverage in Rare Diseases: A TDABC-Based Analysis of Severe Haemophilia A

Tânia Saraiva, Tiago José Leite Cardoso

Rare-disease treatment financing is challenging because high-cost therapies, clinical need, and budget constraints create interdependent decisions among manufacturers, public payers, and healthcare providers. This article combines patient-level time-driven activity-based costing (TDABC) with a sequential reimbursement benchmark and a fixed-budget coverage analysis for severe haemophilia A. Using institutional pathway data and a representative clinical profile, the study estimates an annual treatment cost of EUR 105 …

31.08.2026journal-article

Nephrology

Successful Control of Late‐Onset Nephrotic Syndrome in FN1 ‐Associated Fibronectin Glomerulopathy: A 17‐Year Clinical Course

Nobuhiro Kanazawa, Masayuki Iyoda, Kazuki Abe, Taihei Suzuki, Yoko Shirai, Kenichiro Miura, Kazuho Honda, Hirokazu Honda

ABSTRACT Fibronectin glomerulopathy (FNG) is a rare renal disorder characterized by excessive glomerular fibronectin deposition, often associated with variants in the fibronectin 1 ( FN1 ) gene. Clinically, FNG presents with proteinuria, hematuria, and hypertension, and may progress to end‐stage kidney disease. However, its long‐term clinical course and optimal management remain incompletely defined. We report a sporadic case of FNG in a 26‐year‐old woman carrying an FN1 variant, c.2918A > G (NM_212482.4). Seventee …

31.08.2026journal-article

Journal of Development Administrations Thinking Understand: Public and Business Administration (DATU)

IMPLEMENTATION OF REGIONAL REGULATION NUMBER 7 OF 2016 ON ENVIRONMENTAL CLEANLINESS AND BEAUTIFICATION IN AMUNTAI SELATAN DISTRICT, HULU SUNGAI UTARA REGENCY (Case Study on Special Waste in Environmental Cleanliness)

Rina Safitri, Agus Surya Dharma, Yusran Fahmi

The implementation of Hulu Sungai Utara Regional Regulation No. 7 of 2016 in South Amuntai has not been optimal, marked by pollution due to the disposal and burning of wood waste from the furniture industry. This problem is triggered by low awareness among craftsmen and minimal socialization of the regulations. This study aims to analyze the implementation of the regulation and the factors that influence it in order to realize clean environmental governance. The results show that the implementation of Hulu Sungai U …

31.08.2026journal-article

EPH-International Journal of Humanities and Social Science

IMPACT OF SOCIAL MEDIA USE ON ADOLESCENT MENTAL HEALTH

Susmita Saha

In the 21st century, family structures have undergone remarkable transformation, reflecting broader social, Social media has become an important part of adolescents’ everyday lives, offering opportunities for communication, emotional expression, social support, and access to information, while also presenting potential risks to psychological well-being. This article examines the impact of social media use on adolescent mental health, focusing on social media screen time, cyberbullying, and body-image dissatisfactio …

31.08.2026journal-article

Journal of Community Health Provision

The Influence of the Role of Health Workers, Family Support, and Motivation of Pregnant Women on Compliance with Antenatal Care Visits at the Marawola Community Health Center

Putri Serenggu, Atik Setiawan W, Prima Dewi K, Reni Yuli Astutik, Sentot Imam Suprapto

Compliance with Antenatal Care (ANC) visits is an important indicator in efforts to reduce maternal and infant morbidity and mortality rates. However, the coverage of ANC visits in the working area of ​​Marawola Primary Health Center, Sigi Regency, has not yet achieved the national target. Factors presumed to influence compliance with ANC visits include the role of health workers, family support, and maternal motivation. This study aimed to analyze the influence of the role of health workers, family support, and ma …

31.08.2026journal-article

Bioelectromagnetics in Medicine

Pulsed Field Ablation for Hepatocellular Carcinoma: From Technological Evolution to Clinical Translation

Min Xu, Yuhang Wang, Danxia Xu, Jinhua Pan, Chengyue Zhang, Mengmeng Li, Qiyu Zhao, Tian’an Jiang

Pulsed electric field (PEF) ablation is an emerging non-thermal ablation approach for hepatocellular carcinoma (HCC), with unique bioelectrical effects and potential advantages in treating tumors adjacent to critical structures. This review summarizes recent advances in PEF technologies, including irreversible electroporation (IRE), nanosecond pulsed electric field (nsPEF), and high-frequency irreversible electroporation (H-FIRE), focusing on biological mechanisms, clinical evidence, and future perspectives. Curren …

31.08.2026journal-article

ANNALS OF ABBASI SHAHEED HOSPITAL AND KARACHI MEDICAL & DENTAL COLLEGE

Novel Antibiofilm Compound Using Natural Product against Staphylococcus Aureus and Streptococcus Mutan Considering Biofilm as Real Hazard to Health are System

Naveed Faraz, Tanveer Abbas, Sehrish Shafique

Objectives: To evaluate the antibiofilm activities of natural compound, Mango Leaf Extract (MLE) and Pomegranate Peel Extract(PPE) against Staphylococcus aureus and Streptococcus Mutans. Also use the MLE and PPE in combination so we aim to evaluate the synergistic activity of these two compounds against Staphylococcus Aureus and Streptococcus Mutans as an antibiofim agent because biofilm formation is the main virulence factor of microorganisms to provide resistance against antibiotics.Methods: 96 well plate method …

31.08.2026journal-article

Hematology Reports

The Clinical and Hematological Markers of Pulmonary Embolism: Multicenter Retrospective Study in Mongolia

Javzan-Orlom Dorjjugder, Munkh-Erdene Dashzeveg, Zolzaya Batbold, Amgalandari Byambabaatar, Altankhuyag Nergui, Enkh-Amgalan Tserendorj, Yerkyejan Dungyen, Badamsed Tserendorj, Tumur-Ochir Tsedev-Ochir, Batbold Batsaikhan, Solongo Bandi

Background/Objectives: Systemic inflammation-derived indices, including the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII), have been proposed as convenient and cost-effective predictive markers of mortality and complications in patients with pulmonary embolism (PE). We aimed to evaluate the prognostic performance of hematological inflammatory indices for in-hospital adverse outcomes among Mongolian patients diagnosed with PE. Methods: This mul …

31.08.2026journal-article

Bioelectromagnetics in Medicine

A Multi-Scale Review of Measurement Technologies in Electromagnetic Dosimetry: From Terminal to Environmental Exposure

Miao Cao, Tongning Wu, Zicheng Liu

Background: With the large-scale global deployment of fifth-generation (5G) networks and the proliferation of wearable devices, electromagnetic field dosimetry faces the critical challenge of multi-scale evaluation, extending from the near-field of terminal devices to environmental exposure. Existing reviews mostly concentrate on a single spatial domain, leaving a cross-scale synthesis conspicuously absent. This paper systematically reviews recent technical advancements in dosimetry measurement technologies across …

31.08.2026journal-article

AFRICAN JOURNAL OF REPRODUCTIVE HEALTH

Strengthening reproductive health among female workers through the Gerakan Pekerja Perempuan Sehat Produktif program: Application of the continuous health examination network model in Indonesia

Chendra P. Putra, Afrizal Afrizal, Hardisman Hardisman, Mohamad Reza

The expansion of women in employment warrants more focus on reproductive health and occupational well-being. In Indonesia, the Gerakan Pekerja Perempuan Sehat Produktif (GP2SP) program has been developed to promote the health of female workers. However, the implementation of the program is still limited due to the absence of an integrated operational structure. This research is intended to create a Continuous Health Examination Network (CHEN) model in an effort to improve women’s reproductive health by revitalising …

31.08.2026journal-article

INTERNATIONAL JOURNAL OF PUBLIC RELATIONS AND SOCIAL SCIENCES

Integrated Marketing Communication Strategies on Patronage of Hospitality Organisations in Akwa Ibom State

Christiana Archibong

This study investigates the influence of Integrated Marketing Communication (IMC) strategies on customer patronage of selected hospitality organisations in Akwa Ibom State, Nigeria. The increasing competition within the hospitality sector has necessitated the adoption of coordinated marketing communication strategies that ensure consistency and effectiveness in reaching target audiences. IMC integrates advertising, sales promotion, public relations, and direct marketing to deliver a unified brand message across mul …

31.08.2026journal-article

World Journal of Biology Pharmacy and Health Sciences

PUBLIC HEALTH INTERVENTIONS ADDRESSING MICRONUTRIENT DEFICIENCIES AMONG CHILDREN WITH OBESITY IN THE UNITED KINGDOM: A SYSTEMATIC REVIEW AND NARRATIVE SYNTHESIS

Joseph Olanrewaju Bonire, Peace Agbo Azobor, Yetunde Aigbedion, Olugbade Samson Egbepeju, Anih Genevieve Nneka Olaedo

Background: Childhood obesity can coexist with inadequate micronutrient intake or status, creating a double burden in which excess adiposity does not protect against undernutrition. In the United Kingdom, interventions have commonly targeted diet, physical activity and weight, but the extent to which they correct micronutrient deficiencies in children with obesity remains uncertain. Objective: To synthesise evidence on the effectiveness of UK public health interventions that address micronutrient deficiency in chil …

31.08.2026journal-article

AFRICAN JOURNAL OF REPRODUCTIVE HEALTH

President Xi’s Soft Power “She Power” initiative’s impact on women’s maternal health and schoolgirls in Balochistan, Pakistan

Kamran Saddique, Zheng Lu, Sufyan M. Ramish, Dai Yonghong, Muhammad S. Rao

This paper examines the impact of President Xi Jinping’s Soft Power “She Power” initiative on women’s maternal health and school girls’ livelihoods in Balochistan, Pakistan. Launched by the Chinese Embassy, the initiative distributes 20,000 hygiene kits and conducts health awareness campaigns for schoolgirls. Utilizing a systematic literature review and policy analysis, this study evaluates the initiative against Balochistan’s critical socio-economic indicators, including a Maternal Mortality Ratio (MMR) of 298 per …

31.08.2026journal-article

Antioxidants

Hydroxytyrosol and Olive-Derived Hydroxytyrosol-Rich Products for Skin Health and Prevention of Skin Ageing: Current Evidence and Future Perspectives

Adriana Albini, Danilo Morelli, Cecilia Bender, Paola Corradino

Skin health is increasingly recognised as a key determinant of overall well-being, and its decline is driven by multiple interconnected biological processes. Hydroxytyrosol (HT), an olive polyphenol, exhibits pleiotropic biological activities and has a potential role in supporting skin homeostasis. This narrative review critically evaluates the evidence on oral HT and HT-rich olive-derived nutraceuticals for skin health and healthy ageing with a focus on oxidative damage, inflammation, photoprotection, extracellula …

31.08.2026journal-article

Dentistry Journal

All-on-Four Rehabilitation: A Systematic Review of Clinical Management, Workflow and Complications

Benjamin Reto Huber, Noah Walser, Thiemo Gamma, Philipp Metzler

Background: Severe tooth loss affects approximately 267 million people worldwide and has a significant impact on quality of life and general health. Various prosthetic treatment concepts exist for oral rehabilitation. The All-on-Four concept, first described by Maló in 2003, is considered a modern approach for timely and patient-friendly restoration of oral function and esthetics. Methods: A systematic literature search was conducted in the electronic databases MEDLINE/PubMed and EMBASE (Elsevier). Eligible studies …

31.08.2026journal-article

Artuklu Health

Erken Menopozun Nedenleri ve Cinsel Sağlığa Etkileri

Menekşe Ergül

Giriş: Erken menopoz, 45 yaşından önce over fonksiyonlarının kaybı sonucu menstrüasyon ve üreme yeteneğinin sona ermesiyle ortaya çıkan klinik bir durumdur. Daha genç yaşta görülmesi ve uzun dönemli sağlık sonuçları nedeniyle cinsel sağlık açısından önem taşımaktadır. Hormonal değişikliklere bağlı olarak genitoüriner sendrom, hipoaktif cinsel istek bozukluğu ile vazomotor ve psikolojik semptomlar sık görülmekte; bu semptomlar cinsel sağlığı olumsuz etkileyebilmektedir. Hemşireler, kadınların menopoza ilişkin bilgi …

31.08.2026journal-article

The Journal of International Advanced Otology

Clinical Significance of Neuro-Otological Examinations in Persistent Postural-Perceptual Dizziness: A Retrospective Study

Fumiyuki Goto, Shoji Kaneda, Koichiro Wasano

BACKGROUND: Persistent postural-perceptual dizziness (PPPD) is a chronic functional vestibular disorder characterized by non-spinning dizziness, postural instability, and hypersensitivity to visual and motion stimuli. While Bárány Society criteria enable diagnosis, the prognostic value of neuro-otological examinations remains unclear. To assess the relationship between neurootological test results and short-term clinical improvement in PPPD, clarifying their clinical significance. METHODS: A retrospective review wa …

31.08.2026journal-article

Health Expectations

Bridging Lived and Expert Experience: A Qualitative Study Exploring Lived‐Experience Experts' and Researchers' Experiences of Public Engagement in Cancer Research

Piotr Teodorowski, Beth J. Maclin, Joi Miner, Jonathan B. Green, Daniel G. Garza, Marcus Arana, Edward Duncan, Jonine Figueroa, Sarah S. Jackson, Liz Forbat

ABSTRACT Background Public engagement has the potential to make research more impactful, and it has increased in recent years in cancer research. Yet, there is limited understanding of how this process of bringing lived experience into research works, and of what leads to tokenistic and non‐tokenistic engagement. Aims and Objectives To explore public engagement in cancer research in the United States from the perspective of both lived‐experience experts and researchers. Methods A qualitative study consisting of int …

31.08.2026journal-article

Financial and credit activity problems of theory and practice

REGIONAL DIMENSION OF ECONOMIC DEVELOPMENT IN THE CONTEXT OF ARTIFICIAL INTELLIGENCE IMPLEMENTATION IN PUBLIC ADMINISTRATION

Diana Shkuropadska, Larysa Lebedeva, Kateryna Nikolaiets, Iryna Shtunder, Viktoriya Khrustalova, Yuliya Yasko

The rapid advancement of artificial intelligence technologies and their growing application across various domains of public life are driving fundamental changes in approaches to public administration. Despite the increasing scholarly attention to AI integration in government, the regional dimension of economic development in the context of AI implementation remains insufficiently studied. The purpose of this article is to identify regional features of artificial intelligence implementation in public administration …