Frag' FlorenceEvidenz. Klar. Anwendbar.
Uhr 7/8Sources Journal Tree
Easy Demo

Florence Themenbrowser · Medizin · Seite 127

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
30.08.2026journal-article

Dermatitis®

Reasons for Upadacitinib Discontinuation and Risk of Recurrence in the Treatment of Atopic Dermatitis

Yuxin Luo, Ziyi Zhang, Shu Ding, Li Lei, Jing Chen

Background: Treatment discontinuation is common with Janus kinase inhibitors, such as upadacitinib, in moderate-to-severe atopic dermatitis (AD), and this often results in disease relapse and an increased patient burden. Objective: To explore reasons for discontinuation, risk factors, and willingness to reuse upadacitinib. Methods: This retrospective study enrolled 104 patients with AD (50 in the discontinuation, 54 in the non-discontinuation) from Xiangya Third Hospital (Feb–Mar 2026). Data on DLQI, pruritus NRS, …

30.08.2026journal-article

Journal of Wasit for Science and Medicine

<b>Corrosion of Mild Steel in Saline Environments: Mechanisms, Influencing Factors, and Recent Mitigation Strategies</b><b></b>

Thaqeef Murtada Jawad

Mild steel is prized because of its mechanical qualities and low prices but very vulnerable to corrosion in salty conditions such as in the marine areas. The paper examines its weight loss, potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) corrosion behavior in 3.5 wt.% NaCl. Findings indicate that the rate of corrosion rises with the chloride concentration to a certain optimum and after that, the rate of oxygen diffusion begins to be limiting. High temperatures and acidic PH promote cor …

30.08.2026journal-article

Van Sağlık Bilimleri Dergisi

Evaluation of the effects of I-PRF and L-PRF on postoperative complications after impacted lower third molar surgery

Mehmet Güzel, Volkan Kaplan, Levent Ciğerim

Objective: The objective of this study was to ascertain the impact of L-PRF and I-PRF-impregnated type I collagen on postoperative complications (pain, edema, and trismus) following impacted third molar surgery.Material and Method: The study comprised two groups. The sequence of surgical interventions and the allocation of subjects to groups were determined through a randomization process. Subsequent to the surgical procedure, postoperative measurements were obtained from the patients. The first group received L-PR …

30.08.2026journal-article

International Journal of Medical Sciences And Clinical Research

Detection of Danger Signs of Acute Respiratory Infections Among Under-Fives & Its Relation to Primary Case Management

Prof. Dr. Ilham Amin Jadoue

Acute respiratory infections form one of the most important health problems with high morbidity & mortality rate among under-fives, particularly in developing countries. ARIs, diarrhea & malnutrition are considered the main leading killers of children, their importance as a public health problem are of particular significance in developing countries where the associated mortality in children of (U5) is (30–50) times higher than million deaths a year. Children have about (4–6) ARIs episodes each year & make up a lar …

30.08.2026journal-article

International Journal of Molecular Sciences

Artificial Intelligence and Multi-Omics Approaches in the Precision Management of Pulmonary Hypertension: From Early Diagnosis to Therapeutic Stratification

Sergio Ferrantelli, Alessandro Del Cuore, Giuliano Cassataro, Luigi Dell’Ajra, Rosario Norrito, Giulio Geraci, Gabriella Carmina, Chiara Minà, Vincenzo Polizzi, Nicola Ciancio, Carlo Domenico Maida

Pulmonary hypertension (PH) is a heterogeneous clinical syndrome in which similar haemodynamic abnormalities may arise from distinct vascular, cardiac, pulmonary, thromboembolic, and molecular mechanisms. This complexity limits the ability of conventional classifications and risk scores to fully capture individual disease trajectories and treatment responses. Artificial intelligence (AI) offers a framework for integrating clinical data, electrocardiography, multimodal imaging, invasive haemodynamics, biomarkers, an …

30.08.2026journal-article

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine

Assessing the agreement and reliability of Magene ® for heart rate monitoring

Mila Alves Matos Rodrigues, Thiago Danillo Silva, Jessika Teodoro Santos, Vinnycius Nunes de Oliveira, Nicolas Evangelista Marques, João Victor Rosa de Freitas, Marilia Santos Andrade, Rodrigo Luiz Vancini, Beat Knechtle, Katja Weiss, Ricardo Borges Viana, Claudio Andre Barbosa de Lira

To evaluate the accuracy and reliability of the Magene ® heart rate (HR) monitor compared to the Polar ® H7 (validated device) during rest, maximal graded exercise test, and active recovery. A within-group study was conducted with 68 healthy adults (21 women). Participants completed two laboratory sessions using both monitors in random order. HR values were collected at rest, during the Ellestad maximal treadmill stress testing protocol, and in active recovery. Relative reliability was assessed using the two-way ra …

30.08.2026journal-article

Clinical Medicine (Russian Journal)

Insulinoma

Elsa S. Gaisina, Renata I. Karimova, Olga V. Malyshkina, Tatyana V. Nikiforova

The article presents a description of a clinical case of insulinoma in a 69-year-old female patient. Insulinoma is a rare neuroendocrine tumor originating from the β-cells of the pancreas, the clinical manifestations of which are associated with hyperproduction of insulin/insulin-like factors, leading to the development of a hypoglycemic symptom complex. The presented case highlights the prolonged course and diagnostic difficulty of this disease due to its rare occurrence. The “gold standard” of diagnosis is the 72 …

30.08.2026journal-article

Journal of Clinical Medicine

Hugo RAS Versus Da Vinci in Colorectal Surgery: A Systematic Review and Outcome Meta-Analysis

Sascha Vaghiri, Dimitrios Prassas, Emmanuella Habib, Norma Schmitz-Conti, Wolfram Trudo Knoefel, Andrea Alexander

Background: The advantages of robotic surgery have increasingly led to its rapid adoption in surgical practice. In this context, new robotic platforms such as Hugo RAS have been introduced in recent years to meet the demand for cost-effective alternatives to the well-established Da Vinci system. However, high-quality evidence directly comparing the operative outcomes of these platforms remains scarce. Methods: The current PRISMA and Cochrane guidelines were followed. After careful study selection using the MEDLINE, …

30.08.2026journal-article

Jurnal Kejuruteraan

Effect of Hot Water Treatment on Physical and Mechanical Properties of Oil Palm Empty Fruit Bunch Fibre Cement Boards

Nurul Huda Azmi, Mohammad Soffi Md Noh, Nik Mohd Zaini Nik Soh

The growing demand for sustainable construction materials has increased interest in fibre–cement composites reinforced with natural fibres. Oil palm empty fruit bunch (OPEFB) is an abundant agricultural by-product with strong potential for fibre cement boards. However, its hydrophilic nature and weak fibre–matrix adhesion limit dimensional stability and mechanical performance. While hot water treatment has been shown to improve fibre compatibility, most studies have focused only on untreated, 60°C, and 100°C condit …

30.08.2026journal-article

Aggregate

Dual‐Acceptor Engineered Multimodal Phototheranostic NIR‐II AIEgens for Orthotopic Breast Cancer Treatment

Miaomiao Kang, Yu Pei, Zengming Yang, Yinzhen Pan, Zhijun Zhang, Xue Li, Dong Wang, Ben Zhong Tang

ABSTRACT “One‑for‑all” phototheranostics has emerged as a promising alternative to conventional cancer therapies. Aggregation‑induced emission luminogens (AIEgens) are exemplary templates for constructing such versatile systems. However, developing robust NIR‑II (1000–1700 nm)‐emitting “one‑for‑all” phototheranostic AIEgens remains challenging, due to the drastically lowered reactive oxygen species (ROS) generation capability and strong intermolecular π‐π stacking in the NIR‑II range. To address this, an ingenious …

30.08.2026journal-article

Journal of Personalized Medicine

Optimising Autologous Breast Reconstruction: Pneumothorax and Pneumomediastinum—A Literature Review and First Reported Case of Pneumomediastinum Following Bilateral DIEP Flap Reconstruction

Akshay Soni, Ishith Seth, Kaiyang Lim, Alexander Phan, Richard J. Ross, Mathew Lee, Warren M. Rozen

Background: Thoracic air complications after autologous breast reconstruction (ABR) are uncommon and incompletely characterised. A personalised perioperative approach requires integration of patient anatomy, reconstructive technique, anaesthetic exposures and the postoperative clinical trajectory rather than reliance on population-level estimates alone. Methods: We report a 41-year-old woman in whom pneumomediastinum was identified after bilateral DIEP flap reconstruction and performed a focused literature review r …

30.08.2026journal-article

Genes

Expanding the Phenotypic Spectrum of PRKD1 Gain-of-Function Syndrome: Congenital Heart Disease, Bilateral Carotid Dissections, and Ectodermal Dysplasia in an Adult Patient

Pedram Kharaziha, Klara Junker, Josefine Åhsberg, Antheia Kissopoulou

Background: PRKD1-related congenital heart defects and ectodermal dysplasia syndrome (CHDED) is a rare multisystem developmental disorder caused by heterozygous gain-of-function variants in PRKD1. Reported phenotypes include congenital heart defects, ectodermal abnormalities, limb anomalies, and neurodevelopmental impairment, while vascular manifestations remain poorly characterized. We report an adult patient with a de novo PRKD1 variant and bilateral carotid artery dissections. Methods: Clinical, cardiovascular, …

30.08.2026journal-article

Clinical Case Reports

Rapid Diagnosis and Surgical Management of Catastrophic Stanford Type A Acute Aortic Dissection Resulting in Successful Lung Donation: A Case Report

Koki Yokawa, Ryota Abe, Tomonori Higuma, Kazunori Yoshida, Hidefumi Obo, Makoto Kadotani, Hidetaka Wakiyama

ABSTRACT This case highlights that rapid diagnosis and emergency surgical repair for catastrophic Stanford Type A acute aortic dissection may preserve the opportunity for successful lung donation even when neurological recovery is impossible. Transthoracic echocardiography played a critical role in establishing the diagnosis when computed tomography could not be performed.

30.08.2026journal-article

Journal of Clinical Medicine

Hand Osteomyelitis: Exploratory Associations of Admission C-Reactive Protein and MRI with Surgical Burden and Hospital Length of Stay

Jessica Köller, Alberto Alfieri Zellner, Jonas Roos, Johanna Thiele, Lisa Fiona Roder, Mari Babasiz, Kristian Welle, Christian Prangenberg

Background: Hand osteomyelitis is an uncommon but potentially devastating infection associated with prolonged treatment, repeated surgical interventions, and risk of amputation. Owing to its rarity, evidence regarding prognostic factors and optimal management remains limited. This study aimed to evaluate the clinical characteristics, microbiological findings, treatment strategies, and outcomes of patients with hand osteomyelitis, with particular emphasis on the association of admission inflammatory markers, immunos …

30.08.2026journal-article

Journal of Clinical Medicine

The Eight-Chop Technique in Nonagenarian Patients: Real-World Intraoperative and Postoperative Outcomes

Tsuyoshi Sato

Objectives: To describe intraoperative and postoperative outcomes of the Eight-Chop Technique in elderly patients, with particular attention to nonagenarian patients undergoing cataract surgery. Methods: This retrospective study included consecutive eligible eyes undergoing Eight-Chop phacoemulsification and posterior chamber intraocular lens implantation at a single clinic. Eyes were stratified by age at surgery into 70–79 years, 80–89 years, and ≥90 years groups. Sixty eyes were included in each younger group, an …

30.08.2026journal-article

Jurnal Kejuruteraan

Influence of Bitumen Chemistry and Crumb Rubber Pre-Treatment on the Storage Stability and Rheological Performance of Modified Binders

Naeem Aziz Memon, Nur Izzi Md. Yusoff, Ahmed Suliman B. Ali, Warid Wazien, Aawag Mohsen Alawag, Zubair Ahmed Memon, Shabir Hussain Khahro

The incorporation of crumb rubber (CR) into bitumen offers significant performance and sustainability advantages, yet its widespread adoption is impeded by poor storage stability caused by thermodynamic incompatibility. To address this fundamental challenge, this study investigates the role of bitumen chemistry, specifically the balance of fractions determined via SARA analysis, and the efficacy of crumb rubber pre-treatment in creating a stable binder system. Two base bitumen with distinct chemical compositions (P …

30.08.2026journal-article

European Heart Journal

Antithrombotic therapy after percutaneous coronary intervention in patients with atrial fibrillation: an individual patient data network meta-analysis

Mauro Chiarito, Roxana Mehran, Michael C Gibson, Christopher P Cannon, Renato D Lopes, Samantha Sartori, Angelo Oliva, Kenneth Smith, Yihan Feng, Joshua Lampert, Andreas Goette, Adnan Kastrati, Ruth Owen, Jurrien M ten Berg, Freek W A Verheugt, Pascal Vranckx, Marco Valgimigli, Deepak L Bhatt, John Alexander, Stuart Pocock

Abstract Background and aims Randomized trials demonstrated that in patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) direct oral anticoagulants (DOAC) and a P2Y12 inhibitor reduce bleeding compared with vitamin K antagonist (VKA) plus dual antiplatelet therapy (DAPT) with no increase in ischemic risk; however, important gaps in knowledge remain, limiting certainty and generalizability of these findings. Methods In this patient-level meta-analysis of randomized trials evalua …

30.08.2026journal-article

Frontiers on Healthcare Research

Effect of Preoperative Lactobacillus acidophilus Supplementation on Postoperative Gastric Residual Volume after Lower Digestive Laparotomy: A Randomized, Double-Blind, Controlled Trial

Department of Anesthesiology and Intensive Care, Faculty of Medicine Universitas Indonesia, Christophorus Simadibrata Christophorus, Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Rudyanto Sedono Rudyanto, Sidharta Kusuma Manggala Sidharta Kusuma, Wifanto Saditya Jeo Wifanto Saditya

<p style="font-weight: 400;"><strong>Background:</strong> Gastrointestinal dysmotility is among the most common complications after abdominal surgery and is reflected clinically by an elevated gastric residual volume (GRV), which increases the risk of aspiration and delays enteral feeding. Lactobacillus acidophilus is thought to improve gut motility through luminal acidification, competitive exclusion of pathogens, and direct stimulation of smooth-muscle contractility, but whether this translates into a lower GRV a …

30.08.2026journal-article

Applied Sciences

A Rolling Bearing Fault Diagnosis Method Based on S-LE-EGWO Jointly Optimizing VMD, MCKD and SVM

Fuqiuxuan Liu, Xiaofeng Yue

To overcome the nonlinear and non-stationary characteristics of rolling bearing vibration signals and the challenge of extracting incipient weak fault features, this paper proposes a joint fault diagnosis method based on Variational Mode Decomposition (VMD), Maximum Correlated Kurtosis Deconvolution (MCKD) and Support Vector Machine (SVM). Different from most existing studies that separately optimize individual stages of the fault diagnosis workflow, the proposed method adopts a multi-strategy enhanced grey wolf al …

30.08.2026journal-article

Journal of Artificial Intelligence and Information

Research Progress on the Use of Yue ju Pill in the Treatment of Functional Dyspepsia

Jianing Ma, Hui Ding

Yueju Pill are derived from *Danxi Xinfa*; the formula comprises Atractylodes lancea, Cyperus rotundus, Ligusticum chuanxiong, Shenqu and Gardenia jasminoides, and is primarily indicated for relieving various forms of stagnation. Later generations of medical practitioners have also extended its use to treat disorders of the digestive and nervous systems, amongst others. This article provides a systematic review of the progress made in clinical and basic research on Yueju pill in the treatment of functional dyspepsi …

30.08.2026journal-article

Annals of Clinical and Translational Neurology

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù

ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease pathogenesis. Patients showed increased cerebrospinal fluid levels of neurofilament light chain and chitinases, along with hypermetabolism in the medulla oblongata. C …

30.08.2026journal-article

Iraqi Journal of Science

Estimating Scabies Severity by Epidemiological and Clinical Survey of Baghdad Governorate Patients and Assessing Blood Immune Antibody Levels

Wasan Addai Al-marsomy

Scabies is a parasitic infestation caused by tiny mites Sarcoptes scabiei. Scabies can lead to skin ulcers and serious complications such as septicemia (bloodstream infection), heart disease and kidney problems. Therefore, scabies is considered a dangerous infectious disease that must be treated when diagnosed. The current study aimed to conduct a survey of scabies patients of both genders, examining the role of humoral immunity by estimating certain immunoglobulins (IgM and IgG) and their effect on the patients. H …

30.08.2026journal-article

Medical Science and Discovery

Clinical and Methodological Considerations in Evaluating Amelogenesis Imperfecta as a Systemic Marker: A Critical Commentary

Edgar García-Torres, Oscar Eduardo Almeda-Ojeda, José Manuel Salas-Pacheco

Background and Objective: Recent literature frequently explores the clinical intersections between localized dental enamel variations and systemic health conditions. While multidisciplinary evaluations offer valuable clinical insights, premature conclusions regarding genetic etiologies can introduce significant clinical bias if acquired, pharmacological, and environmental confounders are overlooked. This commentary aims to critically examine a recent case report by highlighting key methodological and pathophysiolog …