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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Annals of Global Health

Catching Up on Mortality, Falling Behind on Disability: A Dynamic Decomposition of the Health‑Adjusted Life Expectancy Gap between Higher‑Income and Lower‑Income Countries

Xue‑Qi Li, Wei Hu, Bo Yan, Jie Sun, Jun‑Yan Xi

Background: Global health inequalities are conventionally assessed through the mortality gap, yet the joint contribution of mortality and disability to health‑adjusted life expectancy (HALE) gap and their dynamic evolution remain poorly understood. We aim to decompose the HALE gap between higher‑income and lower‑income countries into mortality and disability drivers, separate long‑term trends from transient fluctuations, and reveal heterogeneity within the low‑income group. Methods: Using data from the Global Burde …

28.08.2026journal-article

Russian Journal of Clinical Dermatology and Venereology

Rosacea epidemiology: a meta-analysis

G.R. Mustafina, R.R. Mankovskaia, E.S. Kamalov, S.S. Kurbatov

Background. Rosacea is a chronic, multifactorial dermatosis, the epidemiology of which is a pressing issue in modern dermatovenereology. Objective. To analyze the incidence of rosacea in the Republic of Bashkortostan for 2019—2023, as well as to review literature data on the prevalence of rosacea in the Russian Federation and other countries. We studied the structure of rosacea incidence depending on geographic and climatic factors, in particular on the Fitzpatrick skin type. We investugated the relationship betwee …

28.08.2026journal-article

Journal of Experimental & Clinical Cancer Research

Overcoming immune checkpoint inhibitor-mediated T-cell exhaustion with a TCR β chain-directed selective dual T-cell activator

Shantel Angstadt, Lucas A. Horn, Kristen Fousek, Nika Rajabian, Haiyan Qin, Miriam M. Medina-Enriquez, Marcus D. Kelly, Nicole Hsiao-Sanchez, Thomas J. Meyer, Jacques Moisan, Madan Katragadda, Andrew Bayliffe, Zhen Su, Jeffrey Schlom, Claudia Palena

Abstract Background Resistance to immune checkpoint inhibition (ICI) using antibodies against the PD-1/PD-L1 axis remains a significant clinical challenge. Here, we report that combination of anti-PD-1 with a bifunctional fusion molecule, anti-TCRβ-IL-2, comprised of a monovalent Fab that binds and activates the T-cell receptor (TCR) through distinct variable beta (Vβ) chain residues and an IL-2 molecule, mediates robust anti-tumor control in the context of ICI resistance. Methods Syngeneic murine models with varyi …

28.08.2026journal-article

Frontiers in Medicine

Genomic risk profiling in advanced maternal age: a Tamil Nadu prenatal study

Sujithra Appavu, Aruni Wilson Santhosh Kumar, Mukinkumar Sonai, Vinoth Appavu

Background Advanced maternal age (AMA; > = 35 years) is associated with increased fetal chromosomal risk and is an important indication for invasive prenatal diagnosis. This study evaluates karyotyping and chromosomal microarray analysis (CMA) findings among AMA pregnancies in Tamil Nadu, India. Methods In this prospective observational study, 2,200 pregnant women aged ≥35 years who underwent amniocentesis between July 2020 and June 2021 were enrolled. Conventional karyotyping was performed in all cases. CMA was …

28.08.2026journal-article

Frontiers in Medicine

Improvement in liver function and gross motor function after umbilical cord-derived mesenchymal stromal cell transplantation in a child with autoimmune hepatitis and concurrent cerebral palsy: a case report

Liem Thanh Nguyen, Huong Thu Le, Doan Van Ngo, Thi Kieu Trang Phan

Autoimmune hepatitis (AIH) is a complex immune-mediated liver disease of unknown origin that can rapidly progress to liver cirrhosis and end-stage liver failure. Standard treatment regimens typically involve immunosuppressive therapies, with most patients requiring lifelong maintenance. Recently, cell therapy has emerged as a potential therapeutic option for AIH. In this study, we report the case of a 2-year-old boy with type 2 autoimmune hepatitis and postcardiac arrest cerebral palsy who experienced clinical and …

28.08.2026journal-article

Frontiers in Pediatrics

Case Report: Pediatric immune-mediated necrotizing myopathies mimicking inherited muscle disorders: clinical, paraclinical, and genetic insights from two cases

Gianmarco Severa, Maria Camila Cortes-Rojas, Marta Gomez-Garcia de la Banda, Thibaut Belmondo, Audrey Benezit, France Leturcq, Camille Verebi, Baptiste Periou, Eduard Gallardo, Denise Cassandrini, Thierry Gendre, Sophie Hue, Cyril Gitiaux, Nadia Toubal, Sonia Nouioua, Nadira Boucher, Brigitte Bader-Meunier, François Jérôme Authier, Robert-Yves Carlier, Susana Quijano-Roy, Edoardo Malfatti

Objectives Immune-mediated necrotizing myopathies (IMNMs) are a group of rare acquired myopathies. We describe two pediatric cases presenting with early-onset proximal and axial muscle weakness, rhabdomyolysis, and progressive evolution mimicking limb-girdle muscular dystrophy. Methods This retrospective case series is based on a review of the medical records of two pediatric IMNM patients with symptom onset at 2 (P1) and 16 (P2) years of age and diagnoses at 5 and 17 years, respectively. Both patients underwent cl …

28.08.2026journal-article

BMC Medical Ethics

On the blind spot: ethical conflicts of health care professionals in addressing opioid diversion - a template study protocol for multinational qualitative research

Annette Binder, Sonja Mathes

Abstract Background Opioid diversion—the unauthorized redirection of prescription opioids—is a growing global concern with significant public health implications. While diversion can occur at many points in the supply chain, instances involving healthcare professionals (HCPs) are particularly complex, as they often occur within clinical settings and most often involve self-medication, substance use disorders among healthcare professionals, or peer dynamics. These cases raise not only legal and professional concerns …

28.08.2026journal-article

Obesity Surgery

Preoperative Factors Associated with Weight Loss and Recurrent Weight Gain after Bariatric Surgery: A Longitudinal Study in a UK Public Healthcare Setting

Luqman Naim Bin Aizan, Akheel A. Syed, Bilal Alkhaffaf

Abstract Objective Bariatric surgery is an effective treatment for obesity. This study aims to identify demographic factors of weight loss and recurrent weight gain over a 10-year follow-up period. Methods This retrospective observational study includes 2092 patients for overall trends, 1032 patients for predictors of weight loss, and 605 patients for predictors of recurrent weight gain. Percentage total weight loss (%TWL) trends were measured over 10 years. The rate of weight loss and recurrent weight gain was use …

28.08.2026journal-article

BMC Pulmonary Medicine

Impact of CPAP and ventilator system resistance on respiratory effort in healthy volunteers

Simon Lindner, Lena Doerflinger, Luisa S. Drotleff, Burcu Link, Benjamin Neetz, Julia D. Michels-Zetsche, Felix J. F. Herth, Daniel Duerschmied, Simone Britsch

Abstract Introduction Continuous positive airway pressure (CPAP) is widely used for the treatment of acute and chronic respiratory failure and inspiratory support pressure (ΔP insp ) can be added to achieve non-invasive ventilation (NIV). We performed a physiological study to determine the effect of CPAP and inspiratory support pressure on respiratory effort measured by esophageal tidal swings in healthy volunteers. Methods Esophageal tidal swings were measured in spontaneously breathing, healthy volunteers undergo …

28.08.2026journal-article

BMC Public Health

Epidemiological characteristics of hospitalized injury patients in a tertiary hospital of Guangxi Zhuang Autonomous Region, China: a retrospective single-center observational study

Chunxiu Yang, Jun Liang, Qingjiao Nong

Abstract Background Injury is a substantial public health issue that ranks among the primary causes of mortality and disability globally. This study aimed to analyze the epidemiological characteristics and types of injury among hospitalized patients through a single-center hospital-based retrospective study conducted in Guangxi Zhuang Autonomous Region in China. Methods A total of 15,869 hospitalized injury patient records were retrieved from the Hospital Information System (HIS) of the People’s Hospital of Guangxi …

28.08.2026journal-article

Review of Economic Studies

Public Employee Pensions and Municipal Insolvency

Sean Myers

Abstract This paper studies how municipal governments jointly manage spending, credit market borrowing, and a public employee pension system. I model governments as levered investors who must meet non-defaultable pension obligations and may value government spending more than citizens. I quantify the model using data on California cities, including a new record of fiscal emergencies, tax increases required to maintain essential city services. After the financial crisis depleted pension funds, cities engaged in exce …

28.08.2026journal-article

BJPsych International

Clinical predictors of high-risk triage categorisation and in-patient admission in Qatar’s National Mental Health Helpline

Majid Alabdulla, Faisal Khan, Ovais Wadoo, Katja Anneli Warwick Smith, Zeeshan Sheikh, Ahmad Maaen Alater, Yousaf Bilal Iqbal, Rodel Austria Buenaventura, Ahmed Abdelhakim Ahmed Elzok, Aalia Omer Yousif Mohamedahmed, Monyeen Cholette Penullar Vinluan, Benita Mackvin Pereira, Prem Chandra, Yousaf Iqbal

Background Suicide remains a major global public health concern, and crisis helplines are increasingly recognised as important components of suicide prevention. The National Mental Health Helpline (NMHH) in Qatar was established in 2020 as a confidential, multilingual service designed to provide rapid assessment and intervention for individuals experiencing mental health crisis, including suicidality. Aims To identify independent factors associated with high-risk triage categorisation and in-patient admission among …

28.08.2026journal-article

Belitung Nursing Journal

Corrigendum to “The experiences of Chinese colorectal cancer survivors in marital intimacy after ostomy creation: A qualitative study” [Belitung Nursing Journal, 2024; 10(2): 222-230]

Xixi Du, Suchira Chaiviboontham, Bualuang Sumdaengrit

This corrigendum corrects clerical errors regarding the data collection timeline and interview methodology in the original article (DOI: https://doi.org/10.33546/bnj.3212). The authors confirm that these administrative corrections do not affect the methodology, data analysis, results, or conclusions of the original study and sincerely apologize for any inconvenience caused.

28.08.2026journal-article

Public Understanding of Science

Apolitical referee or geopolitical actor? How artificial intelligence’s national-origin labels shape credibility in politicized science communication

Junyi Chen, Weixi Zeng, Yi Mou

Amid the politicization of science and the globalization of technological applications, does the national-origin label of artificial intelligence authors affect their perceived credibility? Drawing on the tension between artificial intelligence as an apolitical referee (machine heuristic) and artificial intelligence as a geopolitical actor like humans (social identity theory and computers-are-social-actors paradigm), two online experiments were conducted in China to examine the role of author type (human, artificia …

28.08.2026journal-article

BMC Health Services Research

Improving the health of Australians with disability: recommendations from a federal-level policy forum

Samia Badji, Helen Dickinson, Hannah Badland, Dennis Petrie, Gwynnyth Llewellyn, Anne Kavanagh

Abstract Background People with disability experience poorer health outcomes than those without disability. These disparities were exacerbated by the onset of the COVID-19 pandemic, prompting the Australian government to implement significant changes to health and other essential services for people with disability. To reflect on these changes, the Centre of Research Excellence in Disability and Health (CRE-DH) – which consisted of investigators from five Australian universities – invited senior government official …

28.08.2026journal-article

ULAKES JOURNAL OF MEDICINE

DERMATITE ATÓPICA E SUA ETIOLOGIA: REVISÃO DE LITERATURA SOBRE FATORES GENÉTICOS, IMUNOLÓGICOS E AMBIENTAIS.

Maria Julia Leal Chimello, Maria Júlia Dias Donegá, Andrea Mariotto de Seixas Neves

A dermatite atópica (DA) é uma doença inflamatória crônica da pele e pode ser associada à genética e ao histórico de condições alérgicas do sistema respiratório, como asma e rinite. Essa patologia, manifesta-se por meio de lesões eritematosas e descamativas e, também, há presença de prurido, o qual piora as lesões. O eczema atópico é mais comum de se iniciar na infância, mas, em muitos casos, persiste até a fase adulta. Este trabalho caracteriza-se como uma revisão narrativa da literatura, realizada através de leva …

28.08.2026journal-article

Frontiers in Child and Adolescent Psychiatry

Co-designing and piloting adolescent-adapted social rhythm therapy for young people with unipolar and bipolar depression: a mixed-methods feasibility case series

Gonzalo Salazar de Pablo, Claudia Aymerich, Zahra Kamran, Cecilia Sanjuan-Ortiz, Nuria Laherran-Cantera, Shantal Zeb, Eleonora Armyra, Allan H. Young, Aditya Sharma, Cornelius Ani, Manasi Kumar, Holly A. Swartz

Objective Depressive and bipolar disorders commonly emerge during adolescence and are associated with disturbances in sleep, daily routines and social rhythms, as well as functional impairment. Social Rhythm Therapy (SRT) targets these processes. However, adult-derived rhythm protocols do not adequately reflect adolescents’ school and family schedules, developmental autonomy, social and digital routines, or preferences regarding monitoring. Direct youth co-design is therefore needed to improve developmental fit, en …

28.08.2026journal-article

Health Affairs Scholar

Primary Care Physician Characteristics and Potentially Inappropriate Medications in Older Adults

Yuki Tatsuno, Catherine A Sarkisian, John N Mafi, Kei Kitajima, Daichi Sato, Yusuke Tsugawa, Atsushi Miyawaki

Abstract Background Potentially inappropriate medications (PIMs) are a growing public health concern. While research in North America suggests physician characteristics were associated with PIM prescription, their generalizability to other countries remains understudied. Methods We conducted a cross-sectional study using a nationwide electronic health record database of primary care clinics in Japan. We analyzed patients aged ≥75 years who visited solo-practice physicians at least quarterly during October 2022 to S …

28.08.2026journal-article

Healthcare

What Is Stressful About Medical Liability? A Retrospective Jurisprudential Analysis of Moral Damages and Discussions on Its Impact on Healthcare Professionals’ Well-Being

Paula Roxana Adi, Bianca Hanganu, Rareș Dorin Pop, Camelia Liana Buhaș, Karla Croitorescu, Mircea Enache, Beatrice Gabriela Ioan

Background/Objectives: Medical liability litigation in Romania has risen steadily over the past decade, yet the quantification of moral (non-pecuniary) damages remains entirely at the discretion of each judge, with no standardized reference. This raises concerns about consistency and predictability, with direct implications for healthcare professionals, who are increasingly exposed to this form of liability—a potential source of occupational stress—and to financial awards they cannot anticipate. The present pilot s …

28.08.2026journal-article

American Journal of Physical Education and Health Science

Psychological Outcomes of BPE Student: A Comparative Study

Kate Mylicka C. Boucher

College students' psychological outcomes are primary global concern today. This study examined the psychological outcomes of BPE students in Davao City, comparing them by age, sex, and year level. The study used a quantitative, descriptive-comparative design with a structured survey administered to 100 randomly selected BPE students. Statistical analyses using ANOVA and t-test showed no significant differences in psychological outcomes by age, sex, or year level. Overall, respondents exhibited a moderate level of p …

28.08.2026journal-article

Health Research Journal of Indonesia

Paparan Media Digital dan Perilaku Seksual Berisiko pada Remaja di SMK Kesehatan di Surakarta

Atur Semartini, Lilik Ariyanti

Perilaku seksual berisiko pada remaja dapat menimbulkan dampak negatif pada kesehatan dan kehidupan remaja. Salah satu faktor yang memicu perilaku seksual pranikah pada remaja adalah keberadaan media digital. Media digital memungkinkan remaja memperoleh berbagai informasi dengan cepat, salah satunya informasi dan konten terkait pornografi dan seksualitas. Penelitian ini bertujuan menganalisis hubungan paparan media digital dan perilaku seksual berisiko pada siswa SMK Kesehatan di Surakarta. Penelitian cross section …

28.08.2026journal-article

Frontiers in Medicine

Real-time vascular monitoring of PDLs and IPL for vascular treatment: effects of fluence and pulse duration on a rabbit ear model

Tun Tun Aung, Yusang Hu, Xiaohan Liu, Manmei Long, Wanyi Wang, Khin Maung Htwe, Soe Lei May, Yuhao Sun, Yixin Zhang, Zheng Zhang

Background Pulsed dye lasers (PDLs) and intense pulsed light (IPL) are commonly used for treating cutaneous vascular diseases but lack standardized and reproducible treatment protocols. Reliable vascular models are needed to visually assess posttreatment responses. Methods Sixteen male rabbits were divided into two groups, with each ear subdivided into three treatment regions. PDL treatment was applied with pulse durations of 0.45 ms (fluences: 4, 5.5, and 8 J/cm 2 ) and 1.5 ms (fluences: 5.5, 8, and 13 J/cm 2 ). I …

28.08.2026journal-article

Frontiers in Surgery

Percutaneous calcium phosphate cement injection for unicameral bone cysts: mid- to long-term clinical and radiographic outcomes

Mengzhang Xie, Zhengxiao Lai, Yi Luo, Li Min, Chongqi Tu, Yong Zhou

Objective Unicameral bone cysts (UBCs) are fluid-filled, osteolytic lesions commonly affecting children and adolescents. Minimally invasive treatments such as percutaneous injection have become increasingly popular. Calcium phosphate cement (CPC), a biocompatible artificial bone substitute with mechanical strength and osteoconductivity, and may be suitable for such applications. This study aimed to evaluate the mid- to long-term clinical and radiographic outcomes of percutaneous calcium phosphate cement injection f …

28.08.2026journal-article

Experimental Biology and Medicine

Extracellular vesicles for abdominal aortic aneurysm: mechanisms, therapeutic potential, and translational challenges

Huibo Ma, Zongyou Xie, Yihang Cai, Fangda Li, Jianqiang Wu, Yuehong Zheng

Abdominal aortic aneurysm (AAA) is a progressive and potentially fatal vascular disease for which no effective pharmacological therapy is currently available. While surgical repair remains the only definitive treatment for advanced aneurysms, patients with small AAAs are mainly managed by surveillance, highlighting the need for disease-modifying strategies. Extracellular vesicles (EVs) have emerged as promising cell-free therapeutic tools because of their biocompatibility, ability to transfer bioactive cargo, and c …