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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
10.08.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

EFICÁCIA DA OZONIOTERAPIA NO TRATAMENTO DE ÚLCERAS DIABÉTICAS: UMA REVISÃO INTEGRATIVA DA LITERATURA

Nicole Alencar Teixeira, Larissa Lima de Abrantes, Mirele Neris Araujo, Sarah Oliveira Viana, Isabel Verlangeiro Vieira, Renata Aparecida Elias Dantas

Esse artigo buscou analisar a eficácia da ozonioterapia em tratamentos com úlceras diabéticas, em comparação aos tratamentos convencionais, através de uma revisão integrativa da literatura. A metodologia consistiu na busca de estudos nas bases de dados bibliográficos PubMed/MEDLINE, Biblioteca Virtual (BVS), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e Web of Science (Coleção Principal da Clarivate), nas quais foram utilizados descritores em ciências da saúde (DeCS), “Ozone Therapy” AND “ …

10.08.2026journal-article

International Journal of Health and Pharmaceutical (IJHP)

Effect of Effleurage Massage On Reducing First-Stage Labor Pain Among Women Giving Birth At Independent Midwifery Practices In Purwakarta Regency, Indonesia

Daris Yolanda Sari, Rika Widiyastuti

Labor pain is a physiological process experienced by every woman during childbirth. Excessive labor pain may increase maternal anxiety, prolong labor, and negatively affect maternal and fetal well-being. Effleurage massage is a non-pharmacological complementary intervention that has been widely used to reduce labor pain because it is simple, safe, inexpensive, and easy to implement in clinical practice. To determine the effect of effleurage massage on reducing first-stage labor pain among women giving birth at inde …

10.08.2026journal-article

Frontiers in Digital Health

Multimodal text-audio sentiment in clinical aphasia speech using NLP

Shamiha Binta Manir, Anai N. Kothari, William L. Gross, Priya Deshpande

Introduction Aphasia affects expressive and receptive communication and may influence the affective tone expressed during clinical speech tasks. This study presents an exploratory weakly supervised NLP analysis of positive/negative affective-tone proxies in AphasiaBank transcripts with paired audio. Methods We extracted sentence embeddings from DistilBERT ( e ∈ R 768 ) and recording-level acoustic summaries ( MFCC 13 , ZCR, RMS, spectral centroid, and spectral bandwidth; a ∈ R 17 ). Text and acoustic features were …

10.08.2026journal-article

Microorganisms

Vaginal Lactobacillus iners Abundance Predicts Response to Local Estrogen Therapy in Postmenopausal Women with Genitourinary Syndrome of Menopause

Xu Han, Baiyun Sun, Yan Zhu, Yanan Liu

Genitourinary syndrome of menopause (GSM) is a common chronic condition in postmenopausal women, yet biomarkers predicting response to local estrogen therapy remain insufficiently defined. In this prospective study, 216 postmenopausal women with GSM received local estradiol vaginal tablet therapy for 12 weeks. Baseline assessments included symptom evaluation, vaginal pH, vaginal maturation index (VMI), and quantitative real-time PCR measurement of six target microorganisms. Treatment response was defined as an impr …

10.08.2026journal-article

Frontiers in Mechanical Engineering

Sensing and assist-as-needed control in lower-limb rehabilitation exoskeletons

Zheng Liancheng, Rizuaddin Ramli, Li Mingtao, Liu Chunhui

Lower-limb rehabilitation exoskeletons are often discussed in terms of mechanics, sensing, and control, yet their rehabilitation value depends on how these elements work together during human–robot interaction. This review focuses on the integration of sensing, compliant actuation, and assist-as-needed control in lower-limb rehabilitation exoskeletons. Recent research suggests that effective assistance depends not only on actuator output, but also on reliable gait-state detection, intention-related sensing, mechani …

10.08.2026journal-article

Molecular Carcinogenesis

DUSP9 Regulates Hepatoblastoma Progression With Implications for Diagnosis and Targeted Therapy

Pingping Zhou, Xiongwei Wu, Qvanxin Yang, Chaojin Wang, Yuhe Duan, Qian Dong

ABSTRACT This study investigated the mechanistic role of DUSP9 in hepatoblastoma (HB) development and progression to provide new insights into the diagnosis and treatment of pediatric HB. Pediatric HB mRNA expression data were obtained from the GEO database. Differentially expressed genes (DEGs) between patients with metastatic and non‐metastatic HB were analyzed using the R software, followed by a functional annotation of the DEGs. Least Absolute Shrinkage and Selection Operator regression and Support Vector Machi …

10.08.2026journal-article

Optics Continuum

Raman spectroscopic assessment of protein structural changes in skeletal muscle induced by low-level laser therapy

Alyaa Jaffer Arabi, Anwaar Al Dergazly

Low-level laser therapy (LLLT) has been extensively investigated as a non-aggressive method to improve muscle performance and enhance recovery. However, the molecular mechanisms of interaction between the lasers and the muscle fibers remain obscure. In this study, we have applied a combined experimental approach of using Raman spectroscopy and measurement of the mechanical performance to investigate the biochemical and functional changes in the skeletal muscles after exposure to the lasers. Raman spectra of the lat …

10.08.2026journal-article

Dermatologica Sinica

The efficacy and safety of monthly intravenous methylprednisolone pulse therapy in Taiwanese alopecia areata patients: A retrospective cohort study

Yang-Yi Chen, Hsin-Yi Huang, Yu-Wen Cheng, Yi-Jia Chen, Cheng-Che E. Lan

Abstract Background: Intravenous methylprednisolone pulse (IVMP) therapy has been widely used for treating severe or recalcitrant alopecia areata (AA), but treatment protocols and efficacy vary. Objectives: This study aims to evaluate the efficacy of IVMP, identify predictive factors for treatment response, and optimize treatment protocols. Methods: A total of 122 AA patients received IVMP (500 mg/day for 3 consecutive days) and were followed for 12 months. Treatment response was classified as remarkable response ( …

10.08.2026journal-article

Frontiers in Pediatrics

Interleukin-6 in complications of prematurity: from biomarker to targeted therapy

Shuzhe Xiao, Qi Zheng, Lingling Wang, Zhiqiu Wang, Guangliang Bi, Jie Yang

Prematurity is a major cause of neonatal morbidity and mortality. Inflammatory imbalance is critical in preterm complications, and interleukin-6 (IL-6) plays a pivotal role in this dysregulation. Currently, there is no comprehensive review focusing specifically on IL-6 in the context of neonatal complications of prematurity. Thus, we review the involvement of IL-6 in various prematurity complications, exploring its mechanisms and clinical implications. We also discuss current and emerging therapies targeting IL-6, …

10.08.2026journal-article

Physiotherapy Research International

Are There Cognitive and Anxiety Improvements in People With Parkinson’s Disease After Xbox Kinect Training Compared With No Intervention? A Non‐Randomized Controlled Trial

Ellen Cristine Ferreira da Silva, Wenderson de Souza Morais, Rodrigo Luiz Carregaro, Patricia Azevedo Garcia, Josevan Cerqueira Leal, Felipe Augusto Dos Santos Mendes

ABSTRACT Background and Purpose Cognitive impairment manifests early in Parkinson’s disease (PD), adversely affecting patients’ daily activities and mental health. Utilizing exergames via the Xbox 360 Kinect (XBK) console presents a promising therapeutic avenue to mitigate cognitive decline in PD. This study aimed to assess the efficacy of the XBK system in enhancing cognitive performance and reducing anxiety levels among individuals with PD. Method A non‐randomized controlled trial, controlled, single‐blind clinic …

10.08.2026journal-article

Health, sport, rehabilitation

Transforming sedentary behavior through sports tourism: Impact on physical activity and exercise enjoyment

Hikmat Kodrat, Abdul Sukur, Hernawan, Sohom Saha, Odilov Otabek, Komil Mukhammadiev, Nuriddin Nazarov, Adilbek Atajanov

Background and purpose This study aimed to evaluate the impact of Sports Tourism Program (STP) on physical activity and exercise enjoyment among sedentary people. Materials and Methods A 12-week pretest-post-test experimental design was adopted. The sample consisted of 48 sedentary people from Sukabumi City. Physical activity and exercise enjoyment were measured at both pretest and post-test phases. Results The analysis revealed a significant increase from pretest to post-test with the most substantial increase was …

10.08.2026journal-article

Biomolecules

Research Progress and Critical Challenges of Bioartificial Kidneys in Renal Replacement Therapy for End-Stage Renal Disease

Luoyi Chen, Qiang Zhang, Yizhong Tu, Tong Chen, Yunliang Xie, Kaixin Lan, Wei Yan, Chunyuan Xue, Shuangjin Yu, Jiang Qiu

Chronic kidney disease (CKD), one of the major global public health burdens, continues to exhibit a rising prevalence worldwide. The growing population of patients with end-stage renal disease (ESRD) has led to an increasing demand for renal replacement therapy (RRT). Although dialysis effectively prolongs survival, it fails to fully replicate kidney function. In addition, the persistent shortage of donor kidneys results in prolonged waiting periods for kidney transplantation. Emerging renal replacement strategies, …

10.08.2026journal-article

Problems of Balneology, Physiotherapy and Exercise Therapy

Оценка бюджетной эффективности федеральных программ развития курортов юга России в условиях санкционных ограничений

О. В. Панина, Н. Л. Красюкова, С. Г. Еремин, С. А. Соболев, А. А. Шахов

Introduction: The redirection of tourist flows to the domestic market under the sanctions pressure of 2022–2025 has led to a significant increase in budget financing of resort territories in southern Russia. The total volume of federal allocations for the national project "Tourism and Hospitality Industry" for 2021–2024 exceeded 200 billion rubles; however, the question of the budgetary return on these investments remains insufficiently studied. Objective: To quantify the budgetary efficiency of federal programs fo …

10.08.2026journal-article

Obstetrics, Gynecology and Reproduction

Personalized endometriosis therapy: efficacy of surgical treatment and long-term medical control

M. A. Chinchenko, V. O. Emelyanova, A. A. Akkubekova, E. I. Islamova, E. G. Kim, M. V. Romanova, E. V. Kokurina, A. A. Ryabtseva, A. A. Vlasova, S. V. Ozornina, A. I. Grebenyuk, R. V. Antonyan, I. M. Abastova

Introduction . Endometriosis is a chronic multisystem disease associated with decreased quality of life, chronic pelvic pain, infertility, and a wide range of comorbid conditions. Despite the fact that laparoscopy has traditionally held a central place in the diagnosis and treatment of endometriosis, the current role of surgical intervention requires a differentiated assessment, taking into account disease phenotype, the severity of pain, reproductive plans, the risk of damage to ovarian reserve and the likelihood …

10.08.2026journal-article

Cancer Gene Therapy

Cancer-associated KBTBD4 mutations induce differentiation defects and confer a unique therapeutic vulnerability

Rohit Sivaprasad, Kristijonas Žemaitis, David Linfeldt, Sudip Ghosh, Anne de Snaijer, Mattias Magnusson, Fredrik Ek, Jenny Hansson, Agatheeswaran Subramaniam

Abstract Epigenetic regulation governs stem cell fate and perturbations in these mechanisms often lead to tumor development. The CoREST complex, a critical regulator of neural and hematopoietic stem cell differentiation, is recurrently targeted by gain of function mutations in the ubiquitin ligase KBTBD4 in high-risk embryonal brain tumors. However, the tumorigenic potential of these mutations remains unresolved partly due to the challenges in modeling tumors that arise during early brain development. We and others …

10.08.2026journal-article

Problems of Balneology, Physiotherapy and Exercise Therapy

Муниципальное регулирование рекреационной нагрузки на курортных территориях особого статуса в условиях роста внутреннего туризма

И. А. Рождественская, А. В. Зубенко, Л. К. Бабаян, А. М. Лаффах, А. А. Татарников

Introduction:The growth of domestic tourism in Russia, which reached 92 million trips in 2024 (an 18% increase compared to 2023), creates unprecedented recreational pressure on resort territories of special status. The Caucasus Mineral Waters (CMW) region, hosting over 9.1 million tourists annually with a simultaneous capacity of only 55,000 persons, experiences structural infrastructure deficit and increasing pressure on balneological resources. Objective: To develop and verify an integrated model for assessing re …

10.08.2026journal-article

Current Issues in Molecular Biology

Photobiomodulation Therapy Enhances Peripheral Nerve Repair by Restoring Nerve Growth Factor Levels and Increasing Myelin Protein Zero Expression After Chronic Constriction Injury in Rats

Mara Evany Oliveira, Fabio Martinez Santos, Adriano Polican Ciena, Marucia Chacur

Neuropathic pain is a chronic condition frequently associated with peripheral nerve injury and is characterized by significant structural and molecular alterations. Photobiomodulation therapy (PBMT) has demonstrated analgesic and anti-inflammatory effects; however, its influence on neurotrophic and myelin-associated repair mechanisms remains incompletely understood. The aim of this study was to investigate the effects of PBMT on ultrastructural, morphometric, and molecular changes induced by chronic constriction in …

10.08.2026journal-article

International Journal of Medicine and Pharmaceutical Research

Targeted Cancer Therapy: Pharmacological Advances in Precision Oncology

Nataraj Palaniyappan, Vijayakumar Murugesan, Kannan Arumugam, M. Ravisankar, Abuthaheer Thajudeen

Cancer remains one of the major causes of morbidity and mortality worldwide and it creates a continuous need for more effective and personalized treatment strategies. Targeted cancer therapy has changed the field of oncology by focusing on specific molecular abnormalities involved in tumor growth, survival, and progression. By selectively interfering with cancer-related molecular pathways, targeted therapies can improve treatment precision and reduce unnecessary damage to normal tissues. Precision oncology brings t …

10.08.2026journal-article

Clinical EEG and Neuroscience

Mu and Beta Oscillatory Changes During a Motor Task Following Rehabilitation in Chronic MCA Stroke: Insights from EEG

Rebeca Pardo-Garcia, Maria Ruiz-Izquierdo, Mercedes Martín García de la Vega, Rocio Calvillo-Torres, George Kontaxakis, Idoya Barca Fernandez, Eva M. Moreno, Lucia Garvin Ocampos, Miguel A. Pozo

Background Stroke in the middle cerebral artery (MCA) often leads to persistent upper limb disability. While clinical scales such as the Fugl-Meyer Assessment for the Upper Extremity (FM-UE) track motor recovery, high-density EEG provides insight into cortical motor-activation patterns. Event-related desynchronization/synchronization (ERD/ERS) in mu and beta bands may offer insight into recovery mechanisms. Objective a) To characterize changes in mu and beta oscillations following upper limb rehabilitation in chron …

09.08.2026journal-article

HIP International

Comparative study of core decompression with allograft and autologous bone marrow therapy plus alendronate versus classical bone graft alone in Ficat grade II–III avascular necrosis of the hip

Ahmed Alkhuzai

Background: Osteonecrosis of the femoral head (ONFH) is a progressive, debilitating condition caused by compromised blood supply, leading to bone cell death and femoral head collapse. Effective early-stage treatments remain limited. Aim: This study compared core decompression (CD) with allograft and autologous bone marrow therapy plus alendronate against classical bone grafting alone in patients with Ficat Grade II–III ONFH, aiming to assess functional outcomes and delay the need for total hip arthroplasty. Methodo …

09.08.2026journal-article

International Journal of Digital Rehabilitation & Therapy

Physiotherapy Approaches to Improve Sleep Quality in Patients with Fibromyalgia: A Systematic Review

Mehmet Çakıroğlu, Deniz Erdan Kocamaz

Fibromyalgia is commonly accompanied by persistent pain, fatigue, disrupted sleep, and psychological symptoms that can restrict daily functioning. This systematic review examined recent evidence on the sleep-related effects of physiotherapy and rehabilitation, together with research linking physical activity to sleep in people with fibromyalgia. PubMed, Web of Science, Scopus, Google Scholar, DergiPark, and the ULAKBİM TR Index were searched for English- or Turkish-language original studies published from March 201 …

09.08.2026journal-article

Phytotherapy Research

Systematic Review and Meta‐Analysis: Plant‐Based Therapy for Irritable Bowel Syndrome

Anselm Meyer, Jonas Auer, Lorena Cascant‐Ortolano, Niclas Schreiber, Amy Zimmermann‐Klemd, Carsten Gründemann, Philipp Busche, Jörg Schirra, Mark R. Fox

ABSTRACT Irritable bowel syndrome (IBS) is a common disorder of brain‐gut interaction that presents with abdominal pain, bloating associated with variable stool consistency. Many IBS patients prefer plant‐based preparations to pharmacological therapy; however, the utility of this approach is not well established. To address this issue, a systematic review with meta‐analysis to assess the efficacy and safety of plant‐based therapy in IBS patients was performed. Literature search with 3 electronic databases (Medline …

09.08.2026journal-article

An-Nahdah Al-'Arabiyah

Speech Acts in Dialogue Between Characters in the Novel "Banat Ar-Riyadh" by Rajaa Alsanea: Sociolinguistic Study

Achmad Syafri Maulana, Ahmad Fauzi, Mohammad Pribadi

This study aims to examine speech acts in the dialogues between characters in Rajaa Alsanea’s novel Banat Ar-Riyadh from a sociolinguistic perspective. The data consist of written utterances from four main characters Qumrah, Sadim, Michelle, and Lamees collected using the listen-and-note technique. A descriptive qualitative approach was applied, employing the act-pair method to identify locutionary, illocutionary, and perlocutionary dimensions, as well as language contact phenomena. The findings reveal two contrast …

09.08.2026journal-article

International Journal of Bilingualism

Exploring Mixed Copies: Evidence From English-Estonian Bilingual Speech

Anna Verschik, Helin Kask

Aims and Objectives/Purpose/Research Questions: Recently, contact linguistics has become increasingly interested in multiword units. At the same time, the code-copying framework (CCF) includes the notion of mixed copies (MCs) that are in-between global copies (‘borrowing’) and selective copies (‘structural change’) and illustrate the transition between the lexicon and grammar. The research question is: What types of MCs occur in English-Estonian bilingual speech? Design/Methodology/Approach: The data were transcrib …