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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Polymers for Advanced Technologies

Advancements in Sodium Alginate‐Based Colloidal Drug Delivery Systems: Bridging Research Into Clinical Practice

Ashutosh Gupta, Aniket Navale, Debadrita Ghosh, Parekh Nirmit Jigneshkumar, Kuljeet Kaur, Aditya Dev Rajora, Soji Soman, Sally A. EL‐Zahaby

ABSTRACT Sodium alginate, an anionic polysaccharide obtained from brown algae and a versatile biomaterial for colloidal drug delivery systems. It has good biocompatibility, biodegradability, and mucoadhesive nature. Alginate has controlled and targeted drug delivery applications. This review discusses sodium alginate–based colloidal systems and presents fundamental research with potential for clinical translation. Alginate can undergo ionic crosslinking with divalent cations such as calcium with a wide range of del …

28.08.2026journal-article

Journal of Clinical Medicine

Diagnostic and Clinical Patterns of Newly Diagnosed ANCA-Associated Vasculitis Before and After the 6 February 2023 Kahramanmaraş Earthquakes: A Multicenter Retrospective Study from Affected Provinces

Sezgin Zontul, Gezmiş Kimyon, Fuat Albayram, Anıl Göçer, Rabia Sağır, Aylin Dolu Karaca, Elif İnanç, Zeynep Kaya, Mesude Seda Aydoğdu, İpek Balıkçı Çiçek, Gözde Yıldırım Çetin, Servet Yolbaş

Background/Objectives: The relationship between large-scale natural disasters and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) remains uncertain. This study compared crude case numbers, diagnostic patterns, and clinical characteristics of newly diagnosed AAV before and after the 6 February 2023 Kahramanmaraş earthquakes in Türkiye. Methods: This multicenter retrospective study included patients newly diagnosed with AAV between 6 February 2020 and 5 February 2026 at five tertiary referral c …

28.08.2026journal-article

Europe’s Journal of Psychology

Effectiveness of cognitive behavioural therapy on sleep outcome for patients with chronic fatigue syndrome in a routine clinical service

Chotiman Chinvararak, Olivia Sterry, Trudie Chalder

Objective We aimed to study the effectiveness of CBT for sleep difficulties in patients with chronic fatigue syndrome/myalgic encephalitis (CFS/ME). Method We conducted a retrospective cohort study at the Persistent Physical Symptoms Research and Treatment Unit, Maudsley Hospital, between 2014 and 2019. The primary outcome was sleep quality and other sleep parameters assessed by the Pittsburgh Sleep Quality Index (PSQI). The secondary assessments comprised the Chalder Fatigue Questionnaire (CFS), the Work and Socia …

28.08.2026journal-article

International Journal for Quality in Health Care

Cultural determinants and strategic priorities for medication safety in acute care: a multidisciplinary Delphi study

Neville Schembri, Hannah-Kim Grima Formosa, Kevin Holmes, Marie Clare Cassar, Shane Desselle, Timothy F Chen, Maria Cordina, Lorna Bonnici West

Abstract Background Organisational culture, defined as the shared values, assumptions, and norms that influence behaviour within organisations, is widely recognised as a key determinant of patient safety in healthcare systems. Within acute care settings, medication safety represents a critical component of patient safety and depends on the ability of healthcare professionals to recognise risks, communicate openly, and intervene before errors result in patient harm. However, medication use is inherently interdiscipl …

28.08.2026journal-article

CLEAN – Soil, Air, Water

Integrated Assessment of Organochlorine Pesticide Residues in Soil and Pepper: Ecological and Human Health Risks

M. B. Adekola, A. M. Taiwo, B. S. Bada, T. M. Oladipo, N. A. Amusa, A. A. Alli, J. O. Alabi, M. F. Olorunnishola, E. N. Danton, S. T. Idowu, Z. O. Afolabi, A. A. Awujoola, R. O. Mustapha, S. S. Oshiomogho, A. M. Olabode

ABSTRACT This study investigated organochlorine pesticide (OCP) residues in agricultural soils and pepper samples to assess their ecological and human health risks. Eighty soil samples (pre‐[40] and post‐[40] pesticide application) and 40 pepper samples were analysed using gas chromatography–mass spectrometry. Bioaccumulation factors (BAFs), health and ecological risk assessments were carried out. Before pesticide application, soils already contained detectable OCP residues, particularly α‐BHC (5.0–5.3 µg/kg) and γ …

28.08.2026journal-article

Acta Paediatrica

Trends in Childhood Underweight in Norwegian Children: Data From Routine Child Healthcare, 2010–2022

Sara‐Rebekka Færø Linde, Roy Miodini Nilsen, Mathieu Roelants, Melissa R. Balthasar, Jennifer L. Baker, Dorthe C. Pedersen, Boye Welde, Marjolein M. Iversen, Petur B. Juliusson, Anne‐Siri Fismen

ABSTRACT Aim This study examined age‐ and sex‐specific prevalence and trends in underweight among Norwegian children and adolescents during the pre‐pandemic period from 2010 to 2019 and COVID‐19 pandemic period from 2020 to 2022. Methods Height and weight data from 78 024 children aged 2 to 13 years in Bergen from 2010 to 2022 were obtained from public health clinic and school health service records. Underweight grades 1 to 3 were defined using the International Obesity Task Force cut‐offs. Age‐ and sex‐specific pr …

28.08.2026journal-article

The Journal of Medicine, Law & Public Health

A Comparison of Patterns, Predictors, and Help-Seeking Behaviours Related to Intimate Partner Violence Among Women in Rural and Urban Communities of Osun State

Ojediran Joke Oluwatoyin, Onayade Adedeji, Olarewaju Sunday, Akinwale John Faniyi

Background: Intimate partner violence (IPV) is a major public health problem with serious physical, psychological, sexual, and socioeconomic consequences for women. This study compared patterns, predictors, and help-seeking behaviours related to IPV among women in rural and urban communities in Osun State, Nigeria. Methods: A comparative cross-sectional mixed-methods study was conducted between May and July 2023 among 500 ever-partnered women (250 rural and 250 urban) selected through multistage sampling. Quantitat …

28.08.2026journal-article

International Journal of Innovative Technologies in Social Science

IMPACT OF OPIOID DEPRESCRIBING AND TAPERING ON MENTAL HEALTH AND SOCIAL FUNCTIONING IN PATIENTS WITH CHRONIC NON – CANCER PAIN: AN OVERVIEW OF CURRENT EVIDENCE

Mateusz Wnęk, Michał Adam Łebek, Wiktoria Zofia Komornik, Jakub Jan Piec, Damian Grębosz, Wojciech Kukiełka, Bartłomiej Andrzej Sałapski, Dominika Weronika Brożyna, Jarosław Dudek, Jakub Dawid Gałwiaczek

Background. Long-term opioid therapy for chronic non-cancer pain is associated with numerous adverse effects, including psychological distress, dependence, and impaired functioning. In response to growing concerns about opioid-related harms, opioid deprescribing and tapering strategies have gained increasing attention in clinical practice. However, their impact on patients’ mental health and social functioning remains incompletely understood. Aim. This review aimed to evaluate the available evidence on the effects …

28.08.2026journal-article

Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale

26 | Health Action Zones profiling and protected discharge pathways in mental health: proposal of an integrated hospital–community care model in ASP Palermo

E. Modica, A. Di Benedetto, A. Li Puma, D. Lipari, A. Firenze

Background. Continuity of care is one of the most critical challenges in the management of patients with severe mental disorders who are at high risk of relapse and rehospitalization. Hospital discharge represents a crucial transition phase during which inadequate integration between hospital and community services may lead to treatment discontinuity and poor clinical outcomes. Analysis of psychiatric hospitalization data within ASP Palermo highlighted a high prevalence of admissions related to psychotic disorders, …

28.08.2026journal-article

REVISTA CHILENA DE ENTOMOLOGÍA

Vespa orientalis Linnaeus, 1771 (Hymenoptera: Vespidae) en Chile: implicancias potenciales para la sanidad apícola en la Región Metropolitana de Santiago

Patricio Vásquez-Quitral, Andrés Vargas-Fernández

Este artículo analiza el potencial impacto ecológico y sanitario derivado de la introducción del avispón oriental (Vespa orientalis Linnaeus) en la Región Metropolitana de Santiago, Chile, tras su establecimiento formal reportado el año 2020 en las comunas de Calera de Tango, Maipú y San Bernardo. Además del impacto destructivo directo en los apiarios mediante la depredación activa y el pillaje agresivo, el asedio de esta especie exótica invasora induce un estrés crónico y colapso demográfico en las colonias de la …

28.08.2026journal-article

Frontiers in Medicine

Clinical efficacy of Masquelet technique in the treatment of tibial and fibular bone defects caused by severe gunshot wounds

Qiming Sun, Yingjie Cong, Wei Sun, Xinwei Liu, Baolei Guo, Chunli Zhao, Baoxian Hou, Ye Liu, Dapeng Zhou

Objective To explore the clinical efficacy of the Masquelet technique in the treatment of tibial and fibular bone defects resulting from severe gunshot wounds. Methods A retrospective analysis was conducted on six male patients (mean age, 23 ± 5 years; range, 18 to 33 years) with tibial and fibular bone defects resulting from gunshot wounds, treated with the Masquelet technique between January 2022 and January 2024. In Stage 1, blood transfusions and fluid resuscitation were administered to manage shock. Wound debr …

28.08.2026journal-article

Global Health Cases

Strengthening Tobacco Control through Multi-Stakeholder Engagement: The Uttarakhand Tobacco-Free Coalition (UTFC) for Protecting Youth and Communities

Awadhesh Kumar, Mamta Thappa, Manish Kumar Singh, Prema Taneja, Sonu Goel

Abstract Tobacco use remains a significant public health concern in Uttarakhand, with 26.5% of adults reported to use tobacco (Global Adult Tobacco Survey [GATS] 2016–17). Although national frameworks such as the Cigarettes and Other Tobacco Products Act (COTPA), 2003 and the National Tobacco Control Programme (NTCP) provide a clear policy direction, implementation at the state level continues to face practical challenges. These include difficult terrain, dispersed populations, and high population movement in pilgr …

28.08.2026journal-article

The British Journal of Psychiatry

Evaluation of the efficacy of support groups in the metaverse for Ukrainian refugees: randomised clinical trial

Cezar Giosan, Catalina M. Popoviciu, Saltanat Zhamaliyeva, Iuliana Zaborot, George Deac, Albert Skip Rizzo

Background Millions of Ukrainians displaced since 2022 experience high rates of depression, anxiety and distress, with major barriers to in-person mental healthcare. Immersive avatar-based virtual reality environments may offer scalable psychosocial support while preserving key therapeutic elements. Aims To evaluate the efficacy of avatar-based virtual reality support groups versus in-person support groups and a waitlist control among Ukrainian refugees in Romania. Method In this 3-arm randomised controlled trial, …

28.08.2026journal-article

Bolu Abant Izzet Baysal Universitesi Tip Fakultesi Abant Tip Dergisi

Distribution of Pain Phenotypes and Their Associations with Clinical, Psychological, and Quality-of-Life Outcomes in Plantar Fasciitis: A Cross-Sectional Study

Bilal Uysal, Ender Salbaş, Nilay Şahin

Background: Plantar fasciitis is traditionally considered a predominantly nociceptive disorder; however, chronic plantar heel pain may include neuropathic-like and nociplastic features that influence clinical presentation and outcomes. This study aimed to describe the distribution of pain phenotypes in patients with plantar fasciitis and to compare clinical, psychological, functional, and quality-of-life outcomes across phenotypes. Methods: In this prospectively recruited cross-sectional study, 100 adults with clin …

28.08.2026journal-article

Nutrients

Clinical Use of Melatonin as a Cross-Sectional Modulator of Oxidative Stress Across the Perinatal Continuum: From Placental Dysfunction to Neonatal Disease

Francesco Cipriani, Elisa Furlan, Luisa Lonoce, Elisa Laschi, Michele Minerva, Lorenzo Perilli, Federica Lotti, Salvatore Grosso

Oxidative stress is a central mechanism linking placental dysfunction, fetal injury, and neonatal disease, supporting the concept of a perinatal oxidative stress continuum that begins during abnormal placentation and may persist after birth. This narrative review explores the biological rationale and current experimental and clinical evidence for melatonin as a potential multitarget intervention across this continuum. Melatonin combines direct antioxidant activity with mitochondrial protection, anti-inflammatory an …

28.08.2026journal-article

Hacettepe University Faculty of Health Sciences Journal

Web-Based Turkish Dichotic Listening Test-Retest Reliability

Öykü Akkay, Emre Eskicioğlu

Objective: This study evaluated the test–retest reliability of a newly developed web-based dichotic listening test with Turkish syllables presented to individuals with normal hearing. By adapting the dichotic listening paradigm from its traditional laboratory implementation to a digital format, this study aimed to increase accessibility. Materials and Methods: Forty-seven participants aged between 18 and 35 with normal hearing completed a web-based Turkish dichotic listening test. Participants were recruited online …

28.08.2026journal-article

International Journal of Public Health and Medical Research

Study on the Effect of Scaffold Carriers on Tissue Repair and Rehabilitation in Cellular Environment

Yuwei Jiang

Scaffold carriers are three dimensional porous biomaterial structures that provide structural support, metabolic signalling and an appropriate cellular environment for tissue regeneration. This article covers the effects of scaffold carrier mechanisms on tissue healing and rehabilitation in three key tissue systems: bone and cartilage, skin and soft tissue and neural tissue. This review integrates principles of extracellular matrix (ECM) biomimicry, scaffold material classification frameworks and cell-scaffold mech …

28.08.2026journal-article

Emergency Medicine Australasia

Indirect ICU Admissions From an Australian Emergency Department: Risk Factors and Outcomes

Daniel McLennan, Cliff Reid, Rhodri Martin, Susannah Olive, Guy Eslick

ABSTRACT Objective Indirect Intensive Care Unit (ICU) admissions, where patients admitted via the Emergency Department (ED) to a non‐critical care ward subsequently require ICU admission, may reflect missed recognition or underestimation of deterioration. This study aimed to: (1) Compare the frequency of indirect ICU admissions in an Australian hospital with international literature. (2) Describe this cohort according to ED care factors, reason for ICU admission, and hospital mortality. Methods Observational cohort …

28.08.2026journal-article

Odovtos - International Journal of Dental Sciences

Association Between Access to Oral Health Information and Use of Fluoride Toothpaste with at Least 1000 PPM in Peruvian Children

Eunji Oh-Aguilar, María Claudia Garcés-Elías, Neila C. Quiroz-Silva, Jesely H. Torres-Ramirez, Roberto A. León-Manco

Oral health education is assumed to improve knowledge and behaviors regarding fluoride toothpaste use. However, dental caries prevention requires comprehensive strategies that integrate dental examinations, provision of fluoride toothpaste, and preventive treatments.To analyze the association between access to oral health information and the use of fluoride toothpaste with a concentration of ≥1000 ppm in Peruvian children under 12 years of age. A cross-sectional analysis was conducted using nationally representativ …

28.08.2026journal-article

Odovtos - International Journal of Dental Sciences

Maternal Knowledge and Practices Concerning Infant Oral Health in a Group of Pregnant Women

Martha J. Arias-Mendoza, Emilia M. Ochoa-Acosta, Andrés A. Agudelo-Suárez

To identify factors associated with the knowledge and practices of pregnant women regarding their children’s oral health. A cross-sectional study was conducted with 269 pregnant women attending two healthcare institutions in the Santander-(Colombia). A questionnaire was carried out, consisting of 40 questions (nine sociodemographic, seven on the psychosocial dimension [D], thirteen on knowledge [K], and eleven on practices [P]). Scoring scales were established for all dimensions, based on the Median (Me) and Interq …

28.08.2026journal-article

Journal of Mechanics in Medicine and Biology

FINITE ELEMENT EVALUATION OF HEALING PERFORMANCE OF NAILING AND PLATING FOR FEMUR SHAFT FRACTURES OF DIFFERENT ORIENTATIONS

SANDEEP RATHOR, RASHMI UDDANWADIKER, NANDRAM SARYAM

Fixation’s flexibility allows for micromotion between fragments, resulting in faster bone healing. In this study, a computational study has been performed to investigate and compare the healing performance of nailing and plating in different stability modes. The diaphyseal fractures in three different orientations have been considered. A nonlinear contact analysis has been conducted on 15 different fixations incorporating the nail and plate. The finite element analysis’s results revealed that the flexibility rather …

28.08.2026journal-article

International Archives of Allergy and Immunology

A Rapid Test Kit for Dust Mite Allergen Detection: Enabling Patient Self-Testing and Environmental Control Assessment

He Zhang, Haibo Jiang, Jiarui Wan, Min Zhou, Guixian Liang, Fengwen Shan, Xinyi Zheng, Yana Zhang, Lei Cheng, Wu Yuan, Jing Su, Qilin Zhou, Qintai Yang

Background: House dust mites (HDM) are the most prevalent indoor allergens and a major contributor to allergic diseases worldwide. Effective monitoring of HDM allergen exposure is critical for clinical management and environmental control, yet the current gold-standard ELISA method is costly, complex, and unsuitable for self-testing. Objective: To develop and validate a rapid, semi-quantitative test kit for dust mite allergens that enables patient self-assessment and localized evaluation of environmental control me …

28.08.2026journal-article

Brain & Heart

Autonomic dysfunction in pulmonary arterial hypertension: Neurocardiological mechanisms and clinical implications

Ilma Nascimento, Victor Cavalcanti Medeiros, Ricely Almeida Tenório Rezende, Vitor Abreu Barreiro, Maria Júlia Torres Lira, Sergio Roberto Pereira da Silva Júnior, Caio Julio Cesar Santos Fernandes

Pulmonary arterial hypertension (PAH) is a progressive cardiopulmonary disease characterized by pulmonary vascular remodeling, increased pulmonary vascular resistance, and right ventricular dysfunction. Although PAH is primarily defined by hemodynamic and vascular abnormalities, growing evidence suggests that autonomic nervous system dysregulation may contribute to its broader clinical phenotype. This narrative review examines the available evidence on autonomic dysfunction in PAH from a neurocardiological perspect …