Frag' FlorenceEvidenz. Klar. Anwendbar.
Uhr 7/8Sources Journal Tree
Easy Demo

Florence Themenbrowser · Alle Themen · Seite 4

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

Evolution, Medicine, and Public Health

Running wild: Forest running enhances performance, enjoyment, mood and future exercise intentions

Matthew J Putland, Stephen J Bailey, Bryna C R Chrismas, Stacy Clemes, Morgan Ewers, Yu-Ling Ho, Eloise Jones, Adelina Lintuluoto, Kirsten McEwan, Riddhi Naik, Hanna Lal Rahimi, Hongbin Xiang, Erik P Willems, Colin N Shaw, Daniel P Longman

ABSTRACT Background and objectives Physical inactivity remains widespread despite the well-established physical and mental health benefits of regular physical activity (PA). There is an urgent need for strategies that increase both uptake and long-term adherence. The Environmental Mismatch Hypothesis proposes that natural environments may increase both engagement and performance of PA. Methodology Forty-seven healthy adults (16 females) completed a randomised, counterbalanced crossover trial. Participants undertook …

27.08.2026journal-article

Angewandte Chemie

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

Shu Chen, Qiyuan Zhou, Jiaqian Xu, Guangyu Zhu

ABSTRACT Photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) have emerged as promising anticancer modalities due to their noninvasive nature, spatiotemporal precision, and high tumor suppression efficacy. Integrating platinum with these phototherapies addresses key limitations of conventional platinum chemotherapy, specifically systemic toxicity and pervasive drug resistance. Since cancer cell membrane proteins, including receptors and transporters, and subcellular organelles play a pivotal role as th …

27.08.2026journal-article

Public Choice

Law enforcement with rent dissipation

Murat C. Mungan, J. Shahar Dillbary

Abstract We consider a framework which brings together losses arising from rent-dissipation and the workhorse model of law enforcement. Governmental actors engage in a contest to share the proceeds from the enforcement of the law through monetary fines, which leads to rent-dissipation. This causes monetary sanctions to be costly, rendering the model used for studying nonmonetary sanctions a better fit for their analysis. The effect of rent-dissipation on optimal sanctions is directly related to the sanction elastic …

27.08.2026journal-article

Frontiers in Neurology

Clinical features associated with cerebrospinal fluid Epstein–Barr virus positivity in autoimmune GFAP astrocytopathy: a multicenter retrospective cohort study

Xing Mao, Qianqian Qu, Chao Quan, Haidong Lyu, Jingzi Zhangbao, Xuan Wang, Hongmei Tan, Xiang Li

Background Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is an inflammatory disorder of the central nervous system. The clinical implications of Epstein–Barr virus (EBV) sequences detected in cerebrospinal fluid (CSF) by metagenomic next-generation sequencing (mNGS) remain uncertain. Methods This multicenter retrospective cohort study enrolled 60 patients with GFAP-A screened from electronic medical records of two hospitals (Jan 2019–Dec 2025). Patients were stratified into CSF EBV-positive ( n …

27.08.2026journal-article

International Journal of Applied Chemistry

Concentrations and Health Implications of PM2.5, PM10, and Gaseous Pollutants in Communities near Ibom Power Company, Ikot Abasi, Nigeria

Ioryue Ijah Silas, Augustine Uche Abel, Idongesit Sunday Ambrose, Akpanuko Mary Emmanuel, Abah Enuwa Bridget, Macdougal Nsikak Saddie, Ekpenyong Ofofonini Ukofia

Particulate Matter (PM) exposure from ambient air has been linked to a number of ailments, and monitoring is necessary in every industrial areas or centers to identify overexposure early. This study's assessed the concentrations of PM2.5, PM10, and related gaseous pollutants in Ibom Power Company, Ikot Abasi, Nigeria, including carbon monoxide (CO), ozone (O3), and nitrogen dioxide (NO2). The concentrations of PM2.5, PM10, NO2, CO, and O3 at three chosen towns surrounding Ibom Power Company were measured using an a …

27.08.2026journal-article

Frontiers in Medicine

The proteomic architecture of clonal hematopoiesis: a systematic review of niche remodeling and multi-compartment predictors of malignant transformation

Jana H. Husein, Rasha M. Khayata, Aisha Jahangir, Ghaith K. Mansour, Ahmed W. Hajjar, Muhammad Raihan Sajid

Background Clonal hematopoiesis of indeterminate potential (CHIP) is a precursor to myeloid malignancies, yet the functional proteomic landscape that governs clonal fitness and microenvironmental remodeling remains poorly understood. This systematic review consolidates high-resolution proteomic evidence to map the transition from stable CHIP to overt malignancy. Methods Following PRISMA 2020 guidelines, we analyzed 15 high-quality studies (selected from 83 initial records) published between 2015 and 2025. The revie …

27.08.2026journal-article

Frontiers in Medicine

Severe recurrent hypernatremia and probable lithium-associated nephrogenic diabetes insipidus following pancreatectomy in a patient with schizophrenia: a case report

Yanfei He, Liuyin Jin, Xiaolei Xu, Qing Xia

Background Nephrogenic diabetes insipidus (NDI) is characterized by impaired renal responsiveness to arginine vasopressin, causing defective urinary concentration and large volumes of dilute urine. Long-term lithium exposure is an important acquired cause. Perioperative fasting, restricted free-water intake, and ongoing fluid losses may unmask compensated lithium-associated urinary concentrating dysfunction and precipitate severe hypernatremia. Case presentation A 61-year-old man underwent laparoscopic resection of …

27.08.2026journal-article

Frontiers in Pediatrics

Risk factors for abnormal bone mineral density in Duchenne muscular dystrophy and the association of regular rehabilitation with bone health

Yi Chen, Shaowei Dong, Meihuan Huang, Guixiang Liu, Turong Chen, Chunming Zhou, Mingsheng Zhang

Background We investigated the prevalence and risk factors of abnormal bone mineral density (BMD) in Duchenne muscular dystrophy (DMD) and explored the potential association of regular rehabilitation with BMD. Methods A cross-sectional study including 215 boys with DMD was conducted. Multivariate logistic regression was used to identify independent predictors, and mediation analysis was performed to explore the pathway linking rehabilitation and BMD. Results Abnormal BMD was found in 62 patients (28.8%). Age was th …

27.08.2026journal-article

Frontiers in Public Health

Association of meteorological exposures with major cancer mortality in Minhang District, Shanghai: a time series study based on distributed lag non-linear models

Jiaqi Guo, Junhui Huang, Chao Xu, Shuili Xuan, Jingyi Ni, Wei Liu, Linli Chen, Yibin Zhou

Objective This study examined the associations between meteorological exposures and major cancer mortality, with a focus on exposure-lag relationships. Methods We collected daily cancer death records and weather data from Minhang District, Shanghai, 2014 to 2023. Joinpoint regression estimated annual percent changes in age-standardized cancer mortality rates. Spearman's rank correlation was employed to explore how meteorological factors related to cancer death. Finally, a distributed lag non-linear model (DLNM) eva …

27.08.2026journal-article

Frontiers in Public Health

Assessment of awareness, usage, and attitudes toward nicotine pouches in Saudi Arabia: a cross-sectional study

Hussain Khalifa Aljumah, Hassan Ali Alradhi, Mujtaba Abbas Alzuwayr, Manal Yousef Alturaifi, Maryam Ali Alamer, Mohammed Naji Albannay, Abdullah Almaqhawi

Background Nicotine pouches (NPs) are emerging smokeless nicotine products marketed as tobacco-free alternatives to traditional smokeless tobacco products. Despite their growing popularity, particularly among youth, limited research exists on their awareness, usage, and attitudes in Saudi Arabia. Objectives This study aimed to assess awareness, usage patterns, and attitudes toward NPs among adults in Saudi Arabia. Methods A cross-sectional, online survey targeting Arabic-speaking adults was conducted between 6 Marc …

27.08.2026journal-article

Nursing Edição Brasileira

Avulsão Completa do Nervo Óptico Secundária a Traumas Maxilofaciais Severos

Eduardo Ferreira Lima, Fernanda de Miranda Santos, Luis Gabriel Agreda Guarachi

A avulsão traumática do nervo óptico (ATNO) é uma das lesões mais graves e catastróficas em traumas maxilofaciais severos, resultando em perda visual irreversível e imediata. Caracterizada pela interrupção física das fibras nervosas entre o globo ocular e o canal óptico, a patologia é frequentemente associada a fraturas orbitárias complexas e deslocamento bulbar. Esta revisão sistemática sintetiza os mecanismos fisiopatológicos, as manifestações oftalmoscópicas e os desafios no diagnóstico diferencial, dado que o e …

27.08.2026journal-article

Pregnancy

Society for Maternal‐Fetal Medicine Special Statement: Quality metrics to assess prenatal detection of congenital heart defects—Updated 2026

Society for Maternal‐Fetal Medicine (SMFM), Adina Kern‐Goldberger, C. Andrew Combs, Afshan B. Hameed, Iffath Abbasi Hoskins, SMFM Patient Safety and Quality Committee

Abstract Congenital heart defects (CHDs) are a leading cause of neonatal morbidity and mortality. Accurate prenatal diagnosis of CHDs can reduce morbidity and mortality by improving prenatal care, facilitating predelivery pediatric cardiology consultation, and directing delivery to facilities with resources to manage the complex medical and surgical needs of newborns with CHD. Unfortunately, fewer than half of CHD cases are detected prenatally, resulting in lost opportunities for counseling, shared decision‐making, …

27.08.2026journal-article

Frontiers in Medicine

Skin phenotype diversity across populations: from skin morphology to molecular phenotype

Xiaoqian Yu, Meiting Yi, Jiayuan Shi, Yan Jia, Liya Song, Huaming He

The considerable range of phenotypic variation observed in human populations may partly reflect distinct processes of natural selection and adaptation to variable environmental conditions. Differences in physiological indices, structure, molecular phenotypes and metabolic mechanisms of the skin across populations with varying skin phototypes are also a reflection of this unique process. These differences are reflected in skin color, pH, moisture content, water loss, sebum secretion, and skin elasticity. The differe …

27.08.2026journal-article

BMC Medical Education

Impact of clinical case discussions in anatomy on national exam performance: a 10-year longitudinal cohort study

Fang Fang, Lan Yu, Yetao Ou, Si Zhou, Jun Ma, Yuntao Peng, Fang Liu, Junfeng Wang, Chunbo Xia, Houzhong Li, Weishan Zhang, Tan Cheng, Yu Chen, Yi Huang, Xin Li, Heng Guan

Abstract Background Traditional anatomy instruction often prioritizes structural memorization over clinical application. Although case-based learning is widely endorsed to bridge this theory-practice gap, longitudinal evidence regarding its sustained impact in foundational sciences remains limited, particularly concerning its performance over a decade amid massive enrollment expansion. Methods This 10-year longitudinal retrospective cohort study tracked seven clinical medicine cohorts (2015-2021). To maintain teach …

27.08.2026journal-article

Plant Health Progress

Current Status of Ceratobasidium theobromae Affecting Cacao and Cassava: Diagnosis and Management

Cansu Oksel, Fulya Baysal-Gurel

Ceratobasidium theobromae, the causal agent of vascular streak dieback in cacao, has recently been associated with cassava witches’ broom disease, expanding its known host range and increasing its importance in crop production systems. This review summarizes disease development, diagnosis, and management of C. theobromae in cacao and cassava. Diagnosis remains challenging due to difficulties in pathogen isolation and confirmation of pathogenicity, although molecular tools have improved detection and identification. …

27.08.2026journal-article

Journal of Clinical Medicine

Late-Course Lactate/Albumin Ratio and In-Hospital Mortality in CRRT-Treated Critically Ill Patients: A Retrospective Severity-Adjusted Analysis

Hasan Şenay, Mehmet Kürşad Orhan, Mahmut Sami Tutar, Munise Yıldız, Ece Ünüvar Şenay, Muhammed Halit Satıcı, Ahmet Erarkadaş, Betul Kozanhan

Background/Objectives: The lactate/albumin ratio (LAR) integrates tissue hypoperfusion and nutritional reserve into a single dimensionless index. As a late-course measurement (last available value before the primary outcome), it may reflect terminal metabolic deterioration rather than early prognostic signal. We examined the association of the final LAR with in-hospital mortality after adjustment for validated severity scores (APACHE II, SOFA) in critically ill patients receiving CRRT, and evaluated its incremental …

27.08.2026journal-article

International Journal of Molecular Sciences

Beyond Swelling: Clinical Insights into the Diagnosis and Management of Hereditary Angioedema

Margarita Paulauskiene, Laura Tamasauskiene, Brigita Gradauskiene

Hereditary angioedema (HAE) is a rare genetic disorder characterized by recurrent episodes of severe, non-pitting edema, most commonly caused by a deficiency or dysfunction of C1 esterase inhibitor (C1-INH), resulting in excessive bradykinin production. HAE subtypes differ according to C1-INH levels, functional activity, underlying genetic variants, and increasingly recognized molecular mechanisms. Awareness of HAE outside specialized medical fields remains limited, and recurrent angioedema may arise through differ …

27.08.2026journal-article

International Journal of Molecular Sciences

Anti-Tumor Potential of Selective L-Type Amino Acid Transporter (LAT1) Inhibitor, JPH203, in Patient-Derived Canine Bladder Cancer Organoids

Ting-Wei Yu, Minami Kawahashi, Fumiya Goda, Ami Kanaya, Mohamed Elbadawy, Hitoshi Endou, Shoichiro Ide, Hideyuki Yamawaki, Masahiro Kaneda, Amira Abugomaa, Tsuyoshi Uchide, Tatsuya Usui, Kazuaki Sasaki

L-type amino acid transporter 1 (LAT1), which controls the neutral amino acid uptake across the cell membranes, has been frequently overexpressed in various human cancers. Overexpression of LAT1 is associated with higher proliferation and shorter patient survival in tumors. Here, upregulated LAT1 expression was observed in patient-derived canine bladder cancers (BCs), and a small-molecule LAT1 inhibitor (JPH203) successfully reduced BC tumor growth both in vitro and in vivo. Patient-derived cancer cells were collec …

27.08.2026journal-article

Frontiers in Global Women's Health

Abdominopelvic hydatid disease during pregnancy: a systematic review of the literature

Evangelos Chinis, Kyriakos Tzanakis, George Lockett, Laura Burney Ellis, Stergios Bobotis, Georgios Geropoulos, Maria Kyrgiou, Konstantinos S. Kechagias

Objective To review the available literature on abdominopelvic cystic echinococcosis (CE) during pregnancy, focusing on clinical presentation, diagnostic approaches, management strategies, and maternal and foetal outcomes. Methods A systematic review was conducted in accordance with PRISMA guidelines. Studies reporting abdominopelvic hydatid disease in pregnant women were included without restrictions on study design or geography. Results Fifty-one studies (45 case reports and 6 case series) including 79 patients w …

27.08.2026journal-article

Veterinary Sciences

Hemodynamic Effects of Intravenous Ephedrine Administration During General Anesthesia for Radiation Therapy in Cats

Daichi Seki, Seijirow Goya, Kenji Teshima, Yoshiki Yamaya

Ephedrine is used as a vasopressor in cats, but the hemodynamic effects of intravenous (IV) administration have not been characterized. This study evaluated the hemodynamic effects of IV ephedrine in 10 cats that developed hypotension during anesthesia. Cats received either saline (SE) or atropine (AE) before ephedrine for hypotension (mean arterial pressure < 60 mmHg). Hemodynamic variables were analyzed using a linear mixed-effects model. No significant differences were observed between groups in the response rat …

27.08.2026journal-article

Australian Health Review

Understanding Australian community members’ knowledge of concussion: a cross-sectional nationwide survey

Sara L. Whittaker, Aleksandra K. Gozt, Lisa Licciardi, Naomi Fuller, Melinda Fitzgerald, Shenane Hogg, Natasha K. Brusco

Objective This study aimed to establish current Australian community knowledge of: (i) mechanisms of concussion injury; (ii) concussion signs and symptoms; (iii) concussion response and management; (iv) pathways of seeking help for a suspected concussion; (v) recovery journey after sustaining a concussion; and (vi) community misbeliefs about concussion. Methods An online survey measured current knowledge of concussion held by the Australian community (≥18 years). Convenience sampling was used for national data coll …

27.08.2026journal-article

dms – der moderne staat – Zeitschrift für Public Policy Recht und Management

Digitale Innovationsförderung im Staat: Institutionelle Einbettung und Integration multipler Logiken am Beispiel des Bundesministeriums für Verkehr (online first)

Norbert Földi

Der Beitrag untersucht die institutionelle Einbettung digitaler Innovationsförderung am Beispiel des Bundesministeriums für Verkehr im Zeitraum von 2016 bis 2025. Auf Grundlage einer qualitativen historischen Dokumentenanalyse zentraler Programmdokumente des Modernitätsfonds (mFUND) rekonstruiert die Studie, wie innovationsorientierte, rechtsstaatlich-administrative, wettbewerbsbezogene und kooperationsorientierte Logiken in einem ministeriellen Förderinstrument miteinander verbunden werden. Theoretisch verortet de …

27.08.2026journal-article

British Journal of Occupational Therapy

Integrating sensory-oriented electrical stimulation with occupation-based, client-centered occupational therapy to support upper limb use after degenerative cervical myelopathy: A case report

Mikari Toki, Takuya Hirose, Sho Maruyama, Hiroki Himeda, Kanta Ohno

Introduction: Degenerative cervical myelopathy often results in persistent upper limb sensory impairment after surgery, limiting functional hand use despite motor recovery. This case report aimed to describe an occupational therapy intervention integrating sensory-oriented electrical stimulation with occupation-based, client-centered practice to support upper limb use after degenerative cervical myelopathy surgery. Method: This case report describes a woman in her seventies with postoperative degenerative cervical …

27.08.2026journal-article

Physiotherapy Research International

Shared Decision‐Making and Patient Enablement in Outpatient Rehabilitation: An Observational Study

Naoto Iwasawa, Shota Hori, Hitoshi Fujita, Takuya Yamada, Hirono Ishikawa

ABSTRACT Objectives To examine the association between shared decision‐making (SDM) and patient enablement in outpatient rehabilitation consultations. Methods In this observational cross‐sectional study, 158 patients attending outpatient rehabilitation at four facilities in Japan were assessed, of whom 93 were included in the final analyses. Sociodemographic data, disease severity (modified Rankin Scale), treatment expectations, control preferences, and health literacy were collected via self‐administered questionn …