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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
26.08.2026journal-article

British Journal of Dermatology

Patient and care partner burden in cutaneous T-cell lymphoma using disease-specific measures of symptoms and health-related quality of life

Julia J Scarisbrick, Larisa Geskin, Sima Rozati, Erika Morsia, Koen D Quint, Amy Musiek, Arvind Arumainathan, Jennifer DeSimone, Richard Cowan, Antonio Giordano, Michi M Shinohara, Cristina Muniesa, Ramon M Pujol, Maria C Goldaniga, Silvia Alberti-Violetti, Kayane Mheidly, Alessandro Pileri, Claire Esler, Luca Nassi, Susan Thornton, Kerry Sandilands, Angela Williams, Annabel Bowden, Jennifer E Dent, Miriam Teoli

Patients with mycosis fungoides (MF) or Sézary syndrome (SS) may experience visible lesions, severe itch, sleep disturbance, body temperature dysregulation and depression. In this international study, 73 patients completed a symptom diary and questionnaires relating to fatigue and health-related quality of life [HRQoL: the MF/SS-cutaneous T-cell lymphoma QoL measure (MF/SS-CTCL QoL)]; 24 care partners also completed an HRQoL questionnaire. Patients reported a high symptom burden that differed between MF and SS, wit …

26.08.2026journal-article

International Journal of Environmental Research and Public Health

Meeting Multiple Needs in Familiar Spaces: Rural Men’s Engagement for Better Health

Latitia Kernaghan, Elyce Green, Brent Smith, Rebecca Barry, Kathryn Castelletto, Natalie Ellis

Rural men in Australia experience poorer health outcomes compared to their urban counterparts, often due to barriers such as limited access to services, cultural norms around masculinity, and geographic isolation. This study explored the motivations underlying rural men’s participation in a student-led health promotion activity conducted by first-year paramedicine students at a large agricultural event. Using semi-structured verbal surveys with 60 participants, qualitative data were collected and analysed through a …

26.08.2026journal-article

JMIR AI

AI Models for Suicide Risk Prediction in Adult Patients Receiving Mental Health Care Using Real-World Data: Retrospective Population-Based Study

Cleofé Peña-Gómez, Marc Fradera, Xavier Sánchez Corrales, Marc Caravaca-Rodriguez, Juan-Francisco Martínez-Cerdá, Joan Albert Escofet, David Roche, Eneko Barbería, Caridad Pontes, Jesús Giraldo, Diego Palao

Abstract Background Suicidal behavior is a major public health problem worldwide. The exact etiology remains unclear, representing a complex problem involving multiple factors. Evidence indicates that around 50% to 80% of people who die by suicide have had contact with the health care system in the year prior to their death. Objective We present the IDICIUS project, whose objective is to develop a clinical decision support system that functions as an early warning system and applies AI to prevent suicide risk using …

26.08.2026journal-article

JMIR Medical Informatics

Bayesian Analysis of AI-Driven Cost Savings in UK and Australian Health Care Systems: Cross-Sector Implementation Study

Jayanta Sarkar, Christopher Drovandi, Sandeep Reddy

Background Health care systems face growing fiscal pressure while AI reaches clinical parity in several domains. UK National Health Service expenditure rose by 52%, while Australia's health expenditure grew by 29% between 2019 and 2023. Yet large-scale cost savings from AI remain limited, largely because implementation constraints continue to outweigh technical capability. Objective This study develops a Bayesian budget-impact framework to estimate AI-driven gross cost savings in radiology, workflow optimization, a …

26.08.2026journal-article

Revista da Associação Brasileira de Pesquisadores/as Negros/as (ABPN)

“AS MULHERES NEGRAS TÊM ATÉ RECEIO DE PROCURAR UMA AJUDA POR SER NEGRA”: PERCEPÇÕES DOS PROFISSIONAIS DA SAÚDE SOBRE GÊNERO, RAÇA E CLASSE NA SAÚDE MENTAL

Eliane Clares Barbosa, Juliana Vieira Sampaio

Partindo do conceito de interseccionalidade, a mulher negra tem sua existência marcada por um sistema de opressões que se cruzam em seu caminho. Foi objetivo deste trabalho descrever a percepção de profissionais sobre a relação das categorias gênero e raça com a saúde mental. Tratou-se de uma pesquisa-intervenção com 16 trabalhadores da Rede de Atenção Psicossocial. Os dados foram analisados a partir do referencial teórico-metodológico das práticas discursivas e produção de sentidos, elencando-se as seguintes categ …

26.08.2026journal-article

Health Expectations

Can It Happen Again? Using Co‐Produced Theatre to Explore the Challenges Faced by Couples Considering Pregnancy After a De Novo Genetic Diagnosis in a Child

Alison Kay, Anne Goriely, Alexa Gummow, Lisa Hinton, Arti Patel, Marysia Price‐Nowak, Shwetha Ramachandrappa, Jonathon Wells, Francesca Wicks, Minna Jeffery

ABSTRACT Introduction When a couple has a child with a genetic condition, it raises questions when considering future pregnancies. It has typically been considered an easier genetic test result to receive when the condition is de novo (new) in origin, because neither parent is understood to have passed on the genetic change, except in rare cases. However, new scientific research indicates de novo changes are more likely to originate from a single sperm—a risk that increases as fathers age. Research on a personalise …

26.08.2026journal-article

Journal of Mid-life Health

Sleep Deprivation, Occupational Stress, and Work-related Determinants of Sleep Disturbance Among Practicing Physicians: A Cross-sectional Study

Prabhat Kumar Agrawal, Shambo Samrat Samajdar, Ruchika Garg, Shatavisa Mukherjee, Prashant Kumar Gupta, Shashank R. Joshi, J Aravinda

A BSTRACT Background: Sleep deprivation and occupational stress are increasingly recognized as critical determinants of physician well-being, with potential implications for healthcare quality and patient safety. However, data on sleep patterns and their determinants among heterogeneous groups of practicing physicians remain limited. Objective: To assess sleep patterns, lifestyle characteristics, and work-related stressors among practicing physicians and to examine their interrelationships. Methods: This cross-sect …

26.08.2026journal-article

Frontiers in Public Health

Associations of healthy lifestyles and physical education enjoyment with physical fitness among Chinese medical students: a cross-sectional study

Xuechen Mao, Yun Zhang

Background Physical fitness is a key indicator for assessing individuals’ current health status and predicting future health outcomes. However, relatively little attention has been paid to the physical fitness of medical students, who will serve as the main workforce in the healthcare industry in the future. This cross-sectional study aimed to explore the current status of physical fitness and to examine the associations of healthy lifestyles and physical education (PE) enjoyment with physical fitness among Chinese …

26.08.2026journal-article

The RAND Journal of Economics

Distributional Effect of Insurer Competition on Premiums: Evidence From the Employer‐Sponsored Health Insurance Market

Haizhen Lin, Yaying Zhou

ABSTRACT We study how insurer competition affects premiums for fully‐insured plans in the employer‐sponsored health insurance market. By utilizing quasi‐experimental variations induced by mergers among national insurers, we show that increased insurer concentration leads to higher premiums, but there exists substantial heterogeneity. In particular, we find that a increase in insurer concentration increases premiums for mid‐sized firms by but reduces premiums for large firms by . We explore additional sources of het …

26.08.2026journal-article

Nepal Journal of Public Health

Delving into the Impacts of Air Pollution on Sex, Health, Environment, and Pollution-related Policies in Nepal: A Scoping Review

Ritika Parajuli, Saurya Aryal, Sabin Khanal, Roshan Pudasaini, Nisam Sharma

Background: Air pollution poses a serious threat to public health as it contributes to a high prevalence of non-communicable diseases (NCDS) such as respiratory illness and cardiovascular diseases. This scoping review aimed to provide an overview of the impacts of air pollution on sex, health, and the environment, with a brief highlight on pollution-related policies in Nepal. It reviews the environmental effects of air pollution and existing policies for controlling air pollution. Methods: This review followed the …

26.08.2026journal-article

Health Science Reports

Colorectal Cancer and Intestinal Protozoan Infections: Prevalence, Risk Factors, and Molecular Confirmation in Western Iran: A Descriptive Case‐Control Study

Alireza Moayyedkazemi, Amal Khudair Khalaf, Sima Nik Khah Behnamiri, Asghar Sepahvand, Neda Niazi, Maryam Sepahvand, Hossein Mahmoudvand

ABSTRACT Background and Aims Infections are recognized contributors to cancer development. This study aimed to assess the prevalence, socio‐demographic characteristics, and risk factors associated with intestinal protozoan parasites in patients with colorectal cancer (CRC) in Western Iran. Methods This descriptive case‐control study enrolled 174 CRC patients and 174 non‐CRC healthy controls receiving care at general hospitals in Lorestan Province between October 2022 and August 2024. Fresh stool samples were examin …

26.08.2026journal-article

Frontiers in Pediatrics

Serial amplitude-integrated electroencephalography trajectories and brain-injury-associated functional immaturity in extremely preterm infants

Yong Zhang, Dekai Xu, Guoyong Luo, Yongping Xu, Yujing Yang, Yong Ji

Objective To characterize postmenstrual-age (PMA)-specific Burdjalov maturation trajectories in extremely preterm infants and to evaluate how imaging-defined major brain injury was associated with these trajectories and with apparent within-cohort discrimination between imaging-defined groups across PMA windows. Methods We conducted a single-center retrospective cohort study of 156 infants born before 28 weeks’ gestation, comprising 109 infants without major brain injury (reference group) and 47 with brain injury, …

26.08.2026journal-article

International Journal of Contemporary Pediatrics

Association of maternal and perinatal factors with umbilical cord blood thyroid profile in newborns: a prospective observational study

Mahesh Jadav, Harini Venugopal, Shruthi Ramiyer Srinivas, Pradeep N.

Background: Congenital hypothyroidism (CH) is a preventable cause of intellectual disability. Cord blood thyroid-stimulating hormone (TSH) is widely used for newborn screening; however, several perinatal factors may influence TSH levels and increase false-positive results. Objectives were to evaluate the effect of maternal and perinatal factors on cord blood thyroid profiles in neonates. Methods: A hospital-based cross-sectional observational study was conducted among 90 neonates. Cord blood samples collected at bi …

26.08.2026journal-article

One Health Journal

Effectiveness of the complex use of antiseptic agents based on alcohols and iodophors in veterinary surgery

P. M. Bezditnyi, V. L. Kovalenko, M. Ye. Romanko, D. O. Popov, T. V. Marchenko, K. S. Miahka, V. V. Kulykova

The aim of this study was to conduct a laboratory and clinical evaluation of the efficacy of the combined use of an alcohol-based antiseptic and an iodophore-based disinfectant in veterinary surgical practice, as well as to determine their synergistic antimicrobial activity against clinical veterinary isolates. Additionally, the study investigated the effect of the combined antiseptic regimen on the incidence of postoperative infectious complications, wound healing rates, and local tolerability in animals following …

26.08.2026journal-article

Journal of Child Neurology

Safety and Local Tolerability of Diazepam Nasal Spray for Children With Epilepsy Aged 2-5 Years: Final Results of a Phase 1/2a Trial

Eric B. Segal, James W. Wheless, Steven M. Wolf, Muhammad Zafar, J. Ben Renfroe, Miguel A. Lopez-Toledano, Leock Y. Ngo, Adrian L. Rabinowicz, Enrique Carrazana

Diazepam nasal spray is approved to treat seizure clusters in patients aged ≥2 years. A long-term safety study in patients aged 6-65 years found a safety profile similar to diazepam rectal gel. We conducted an open-label, phase 1/2a trial of diazepam nasal spray in children with epilepsy aged 2-5 years with motor seizures or seizures with clear alteration of awareness. After a pharmacokinetic period, caregivers were instructed to use diazepam nasal spray (0.5 mg/kg) as needed for frequent seizures or seizure cluste …

26.08.2026journal-article

British Journal of Multidisciplinary Studies

Optimizing Focus Group Probes in Health Sciences to Unlock Insights into Undergraduate Realities and Coping Dynamics

Mustafa M. Bodrick, Lobna A. Aljuffali, Mutlaq B. Almutairi, Aws A. Obaid

The use of qualitative research focus groups in health sciences leverages group synergy to explore complex experiences, yet the strategic execution of probes within these group dynamics remains somewhat under-examined compared to one-on-one interviews. This study review optimizes the use of probes with prompts for clarification on questioning as precision tools to unlock deep insights into undergraduate realities and coping dynamics. Grounded in phenomenological and ethnographic philosophies, the review contrasts t …

26.08.2026journal-article

Frontiers in Public Health

Resilience and social support as correlates of dementia risk: insights from a biopsychosocial analysis of the All of Us dataset

Casey D. Xavier Hall, Zhuo Meng, Beth Okantey, Crim Sabuncu, Brittany Lane, Ladanya Ramirez Surmeier, Julia Sheffler, Diana C. Oviedo, Frank Y. Wong, Gabrielle B. Britton, Eugenia Millender

Introduction Cognitive decline is a growing concern in the United States as the population ages. Risk scores such as the Cardiovascular Risk Factors Aging and Incidence of Dementia (CAIDE) have been validated to assess long-term risk for cognitive decline. The existing literature has primarily focused on biological risk factors; however, there is a growing emphasis on integrating psychological and social factors that may contribute to a greater risk of cognitive decline. Methods This study uses a large administrati …

26.08.2026journal-article

Health Security

Establishing and Maintaining a Safety Training Program at Scientific Institutions

Segaran P. Pillai, Cristina M. Rodriguez, Marisa J. Newcomer

Employers have a legal and ethical responsibility to provide a safe working environment for their employees. Safety training demonstrates a commitment to fulfilling this responsibility, fostering a sense of trust and accountability. Safety training is important for maintaining a safe and healthy work environment, complying with regulations, and promoting overall wellbeing within organizations and communities. A good safety training program has numerous benefits including (1) employee satisfaction, (2) risk mitigati …

26.08.2026journal-article

International Health Sciences Review

Acute traumatic coagulopathy: new concepts in endotheliopathy and hemostatic resuscitation

Ana Clara Pessoa Pontes, João Francisco Ferreira Andriola, Gabriel Alves Groff, Carla Lúcia de Camargo, Elisângela da Silva Mendes Nunes, Paulo Rogério Vieira Lamarca Flores

Acute traumatic coagulopathy (ATC) is an early and complex manifestation of trauma-induced coagulopathy that develops through the interaction of hemorrhagic shock, tissue hypoperfusion, endothelial dysfunction, glycocalyx degradation, inflammation, and dysregulated fibrinolysis, contributing substantially to preventable trauma-related mortality. This narrative review aimed to summarize current evidence regarding the pathophysiological mechanisms underlying ATC, with emphasis on trauma-induced endotheliopathy, and t …

26.08.2026journal-article

Journal of Paediatrics and Child Health

Peripheral Blood Eosinophil Count as a Predictor of Corticosteroid Resistance in Paediatric Asthma: A Prospective Observational Study

Shravya S. Rao, Karthik Subrahmanya, Vishwas Kadambila

ABSTRACT Background Asthma is one of the most common chronic inflammatory disorders in children and remains a major cause of morbidity worldwide. Although inhaled corticosteroids (ICS) are the cornerstone of long‐term asthma management, a considerable proportion of paediatric patients exhibit reduced responsiveness to corticosteroid therapy, resulting in persistent symptoms, frequent exacerbations, impaired quality of life and increased healthcare utilization. Early identification of children at risk of corticoster …

26.08.2026journal-article

Frontiers in Oral Health

Labeled ingredient composition and literature-reported hazard signals in children's toothpastes available through selected UAE retail sources

Sally Manla, Manal Al Halabi, Abiola Senok, Rania Nassar, Anas Salami, Iyad Hussein, Mawlood Kowash

Background Young children frequently swallow toothpaste during brushing, making the composition of ingredients and the context of exposure relevant to pediatric oral care. Objective To conduct a descriptive survey of children's toothpastes available through selected UAE retail sources and to develop a structured evidence map of literature-reported biological effects associated with labeled ingredients, without performing product-level safety or risk assessment. Methods We surveyed children's toothpastes marketed in …

26.08.2026journal-article

N.N. Priorov Journal of Traumatology and Orthopedics

Rehabilitation potential for CNS pathology in patients with musculoskeletal dysfunction using the categories of the International Classification of Functioning, Disability and Health (ICF)

Boris B. Polyaev, Mikhail B. Tsykunov, Olga V. Fuchizhi, Mariya A. Bulatova, A. Y Suvorov

Introduction.Determining the rehabilitation potential (RP) is a key stage in planning medical rehabilitation (MR). The International Classification of Functioning, Disability and Health (ICF) provides a standardized method for assessing impairments, including from the perspective of a physical therapist (PT) as a leading member of the multidisciplinary rehabilitation team (MDRT). The assessment of the musculoskeletal system in patients with CNS pathology is particularly important, as it serves as the primary effect …

26.08.2026journal-article

Health Science Reports

Cardiovascular Diseases: Exploring Epidemiology, Pathophysiology, Risk Factors, and Medicinal Plant‐Based Therapies: A Narrative Review

Nawfal Hasan Siam, Umme Halima Mithila, Sadia Alam Tisha, Hridoy Saha, Ayesha Binte Mahbub, Farhan Nizam, Johirul Islam, Noushin Tabasumma, Md. Mazharul Islam Chowdhury

ABSTRACT Background and Aims Cardiovascular diseases (CVDs) remain the leading cause of global morbidity and mortality, encompassing coronary artery disease, hypertension, heart failure, and cerebrovascular disorders. The global burden of CVD continues to rise, driven by complex interactions among endothelial dysfunction, oxidative stress, inflammation, genetic predisposition, and lifestyle‐related risk factors. This review aims to provide a comprehensive overview of the epidemiology, pathophysiology, risk factors, …