Frag' FlorenceEvidenz. Klar. Anwendbar.
Uhr 7/8Sources Journal Tree
Easy Demo

Florence Themenbrowser · Alle Themen · Seite 50

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Journal of Clinical Psychology in Medical Settings

Treating Multiple Chemical Sensitivity as a Specific Phobia Using Cognitive Behavioural Therapy: A Case Study in an Older Adult

Matthew Wilcock, Alice Loyal, David Hitt

Abstract Multiple Chemical Sensitivity (MCS) is a poorly understood condition characterised by physical symptoms triggered by minimal exposure to odorous or chemical agents, often without identifiable organic pathology. This case study describes cognitive behavioural therapy (CBT) for MCS in an older adult referred to a respiratory team after developing persistent, generalised reactions to odours following an acute toxic inhalation. Symptoms led to severe avoidance, functional impairment and suicidal ideation. Foll …

28.08.2026journal-article

Belitung Nursing Journal

Clinical and nursing correlates of severity among chronically ill adults with aspiration pneumonia in Saudi Arabia: A retrospective cross-sectional study

Eman M. Gaber Hassan, Myra Cusi Britiller, Mohammad Daud Ali, May Mohammed Alshowikat, Fatimah Hassan Ahmed Alduhaim, Sarah Mohammad AlOtaibi, Asmahan Shabbab Hamad Al-Mutairi, Hassna Maquta Ali Alharthi, Dalal Sanad Almutairi, Fatimah Saleh Al Awami, Shimaa Mohammed Said

Background: Aspiration pneumonia is a major cause of morbidity and mortality in hospitalized adults, yet limited evidence exists from the Eastern region of Saudi Arabia. Objective: To identify clinical correlates of disease severity in patients with confirmed aspiration pneumonia. Methods: A retrospective cross‑sectional study was conducted using medical records of adult patients diagnosed with aspiration pneumonia across two major hospitals in Eastern Saudi Arabia (January 2018 – December 2023). A total of 294 eli …

28.08.2026journal-article

Hacettepe University Faculty of Health Sciences Journal

Effects of Gluten-Free Diet on Nutritional Status and Some Inflammation Parameters in Adult Celiac Disease Patients

Öznur Aydın, Evrim Kahramanoğlu Aksoy, Zeynep Göktaş

Objectives: Celiac disease is a lifelong autoimmune disorder in which strict adherence to a gluten-free diet is the cornerstone of treatment. However, many patients follow the gluten-free diet incorrectly due to limited nutrition education, which may affect nutritional adequacy, inflammation, and quality of life. This study aims to examine the effect of a gluten-free diet on nutritional status, anthropometric measurements, and serum interferon-gamma and interleukin-15 levels in adult celiac patientsMaterials and Me …

28.08.2026journal-article

Journal of the Society for Clinical Data Management

Project Management for Clinical Data Managers

Sachi Amatya, Dawn Edgerton, Helen Fasshauer, Stacey King, Erica Sage

Project management skills are critical for clinical data managers (CDMs) because high-quality clinical data must be delivered in compliance with ICH E6(R3) and ICH E8(R1) while coordinating complex, decentralized, and technology-enabled clinical trial environments. These skills enable effective planning, risk management, stakeholder communication, and oversight of timelines, budget, and resources across clinical portfolios and programs. CDMs are accountable for data integrity and end-to-end clinical data strategy; …

28.08.2026journal-article

Annals of Global Health

Catching Up on Mortality, Falling Behind on Disability: A Dynamic Decomposition of the Health‑Adjusted Life Expectancy Gap between Higher‑Income and Lower‑Income Countries

Xue‑Qi Li, Wei Hu, Bo Yan, Jie Sun, Jun‑Yan Xi

Background: Global health inequalities are conventionally assessed through the mortality gap, yet the joint contribution of mortality and disability to health‑adjusted life expectancy (HALE) gap and their dynamic evolution remain poorly understood. We aim to decompose the HALE gap between higher‑income and lower‑income countries into mortality and disability drivers, separate long‑term trends from transient fluctuations, and reveal heterogeneity within the low‑income group. Methods: Using data from the Global Burde …

28.08.2026journal-article

Russian Journal of Clinical Dermatology and Venereology

Rosacea epidemiology: a meta-analysis

G.R. Mustafina, R.R. Mankovskaia, E.S. Kamalov, S.S. Kurbatov

Background. Rosacea is a chronic, multifactorial dermatosis, the epidemiology of which is a pressing issue in modern dermatovenereology. Objective. To analyze the incidence of rosacea in the Republic of Bashkortostan for 2019—2023, as well as to review literature data on the prevalence of rosacea in the Russian Federation and other countries. We studied the structure of rosacea incidence depending on geographic and climatic factors, in particular on the Fitzpatrick skin type. We investugated the relationship betwee …

28.08.2026journal-article

Journal of Neuro-Oncology

CAR-T cell therapy: potential for paediatric brain tumours—an update

Alexandra Zehner, Benjamin Draper, Darren Hargrave, Laura K. Donovan, John Anderson

Abstract Central nervous system (CNS) tumours are the deadliest cancer for children and currently present limited treatment options. Chimeric antigen receptor (CAR)-T cell therapies have emerged as an innovative approach supported by encouraging clinical results. Current clinical trials using CAR-T cells in the treatment of paediatric CNS cancers differ in a number of variables, including the CAR-T cell route of delivery, presence of lymphodepletion, identified target antigen, and CAR engineering features. Consider …

28.08.2026journal-article

Ciência et Praxis

Perfil socioeconômico, dor e desconforto em profissionais da Estratégia Saúde da Família de um município nordestino.

Tarcisio Viana Cardoso, Fernanda Pereira Lélis de Lima, Mayara Junqueira de Oliveira

Introdução: O adoecimento de profissionais da Atenção Primária está associado a fatores psicossociais e condições organizacionais que impactam diretamente sua saúde e desempenho. Objetivo: Analisar o adoecimento de profissionais da Estratégia Saúde da Família em Guanambi, Bahia, com foco na dor e desconforto. Métodos: Estudo descritivo, transversal e quantitativo, baseado em dados do Sistema de Cadastros Nacionais de Estabelecimentos de Saúde, relatórios da Secretaria Municipal de Saúde e questionários aplicados ao …

28.08.2026journal-article

ARACÊ

A GESTÃO ESCOLAR FRENTE À IMPLEMENTAÇÃO DA LEI Nº 15.100/2025: DESAFIOS DA RESTRIÇÃO AO USO DE CELULARES NAS ESCOLAS PÚBLICAS ESTADUAIS DA BAHIA

Maximiliano José Carvalho Varjão

Considerando os desafios enfrentados pelas escolas públicas diante da presença constante dos celulares no ambiente educacional e da implementação da Lei nº 15.100/2025, que estabelece restrições ao uso de aparelhos eletrônicos por estudantes, esta pesquisa busca compreender as dificuldades enfrentadas pelos gestores escolares nesse processo. Objetiva-se analisar os desafios relacionados à implementação da legislação, considerando as percepções dos gestores e as estratégias adotadas pelas unidades escolares. Para ta …

28.08.2026journal-article

Medicine

Association between red blood cell distribution width to albumin ratio and periodontitis in US adults

Lina Zhu, Ke Yang, Qian Zheng, Wenhao Qian

Research on the potential relationship between RAR and periodontitis remains unclear. This study examines the association between RAR and periodontitis among US adults, utilizing data from the National Health and Nutrition Examination Survey (NHANES; 2009–2014). Weighted multivariate logistic regression analyses, restricted cubic spline curve (RCS) models, and subgroup analyses were utilized to evaluate the relationship between RAR and periodontitis. Additionally, sensitivity analysis was used to evaluate the robus …

28.08.2026journal-article

Medicine

Causal relationship between asthma and hernia risk

Yao Lu, Huiping Yuan, Debing Li, Guanghui Yang, Xu Liu, Xian Wang, Ke Zhang, Dechun Liu

Epidemiological associations between asthma and various hernia subtypes have been reported, but the causality and direction remain unclear. This study employs a two‑sample Mendelian randomization (MR) approach to systematically assess the causal associations between asthma and 6 hernia subtypes. Using publicly available summary data of genome-wide association studies, asthma was selected as the exposure, and diaphragmatic hernia, umbilical hernia, femoral hernia, hiatus hernia, inguinal hernia, and ventral hernia w …

28.08.2026journal-article

Journal of Medical Genetics

Exploring the clinical and mutational spectrum of MORC2 -associated disorders

Aysylu Murtazina, Eugenii Tatarsky, Iuliia Viakhireva, Artem Borovikov, Alexandra Filatova, Elena Dadali, Nina Demina, Natalia Semenova, Tatiana Markova, Ludmila Bessonova, Dmitrii Subbotin, Bakhytkul Myrzaliyeva, Marcello Scala, Kameryn Butler, Cyril Mignot, Hannah Moore, Neena Champaigne, Arnaud Isapof, Valeria Capra, Claudio Bruno, Federico Zara, Romano Tenconi, Ilya Kanivets, Andrey Marakhonov, Olga Shchagina, Timofei Vizerov, Philipp Sviridov, Oxana Ryzhkova, Sergey Kutsev, Mikhail Skoblov

Background Pathogenic missense variants in the MORC2 gene are associated with two distinct disorders: Charcot-Marie-Tooth disease type 2Z (CMT2Z) and the recently described DIGFAN (developmental delay, impaired growth, dysmorphic facies and axonal neuropathy) phenotype, which encompasses a broad range of clinical manifestations that vary significantly between individuals. Methods Clinical and imaging data from 16 patients were collected. Western blot analysis was performed on 10 identified variants in affected pati …

28.08.2026journal-article

PLOS One

Willingness of nursing undergraduates to work in long-term care facilities: A qualitative study

Xiufang Hou, Yanglan Wang, Fangfang Wang, Qiuping Li

Purpose This study aimed to explore the willingness and attitudes of undergraduate nursing students enrolled in a geriatric nursing minor program toward pursuing careers in long-term care facilities. Methods A qualitative phenomenological approach was adopted. Semi-structured, in-depth individual interviews were conducted with fourteen students minoring in geriatric nursing. Interview transcripts were analyzed using thematic analysis. Results The analysis identified three primary themes: (1) Nascent Interest in Ger …

28.08.2026journal-article

Environmental Research: Health

“We can overcome it by ourselves”: Culturally-informed perceptions of service access by Chinese seniors in Vancouver’s Chinatown

Erika Siao, Lam Fung Liu, Michelle Yeung, Abby Zhou, Ashley Wan, Nicole Chin, Liv Yoon

Abstract This paper proposes using a culturally-informed perspective to understand the nuances and complexities of marginalized communities’ access (and lack thereof) to climate adaptation services. Following a previous study from Yoon et al. (2025), focus groups and subsequent analysis were conducted with 31 Chinese seniors in Vancouver’s Chinatown community. Building on Yoon et al. (2025)’s findings, this paper illustrates the tensions and grey areas behind Chinese seniors’ experiences and perspectives towards wa …

28.08.2026journal-article

Perspectives on Sexual and Reproductive Health

Anticipated Negative Impact of Dobbs v. Jackson Women's Health Organization Among Young Adult Black Women in the US

Aaliyah Gray, Shelly Sinclair, Mary Jo Trepka, Kimberly M. Nelson

ABSTRACT Purpose The United States Supreme Court case Dobbs v. Jackson Women's Health Organization overruled federal protections for abortion in 2022. Young adult Black women (YABW) are expected to be among those most impacted directly by abortion restrictions and indirectly by effects on broader sexual and reproductive health access. This study assessed the extent to which this population anticipates negative impacts of the ruling. Methods A nationwide convenience sample of 500 YABW 18–22 years participated in an …

28.08.2026journal-article

Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale

29 | From collective catering to the ward: clinical and environmental analysis of a polymicrobial gastroenteritis outbreak

C. E. Rizzo, D. Anzà, D. Sciacca, S. D'Amico, V. Calabrese, C. Sindoni, C. Genovese, V. Restivo

Background. Foodborne and waterborne diseases represent a critical threat to immunocompromised patients, in whom reduced immune surveillance can exacerbate the clinical course of common pathogens [1]. This study analyzes a cluster of polymicrobial gastroenteritis stemming from a single point-source exposure, comparing the severity of clinical manifestations among patient with different clinical conditions. Materials and Methods. A 43-year-old woman undergoing active chemotherapy for cervical carcinoma was admitted …

28.08.2026journal-article

Reviews on Recent Clinical Trials

The AI Revolution: Shaping the Present and Future of Pharmaceutical Research and Development

Krishna Chandra Panda, B.V.V Ravi Kumar, Jammula Sruti, Ch Niranjan Patro, Bimalendu Chowdhury, H. K. Sundeep Kumar

Abstract: The transformative role of artificial intelligence (AI) in the pharmaceutical industry is examined, with a focus on its significant contributions to drug discovery, development, and clinical trial processes. It highlights the inefficiencies and high costs associated with traditional drug development and explores how AI and machine learning (ML) can enhance these processes by analyzing extensive biological datasets. The historical context of AI in pharmaceutical development is examined, noting how advances …

28.08.2026journal-article

Health Education & Behavior

The Health Education Specialist Practice Analysis III 2025 (HESPA III 2025): Process and Outcomes

Antonio J. Gardner, Beth H. Chaney, Ian F. Hembry, James Henderson, Misozi Houston, William Datema, Cherylee Sherry, Shontelle Dixon, Melissa Opp

The Health Education Specialist Practice Analysis III 2025 was conducted to update and validate the hierarchical model associated with the contemporary framework for the practice of health education specialists across work settings at entry and advanced levels. The purpose of this manuscript was to report the processes and findings associated with the HESPA III 2025 study to assess the validity of the Areas of Responsibility, Competencies, Sub-competencies, and Knowledge Areas for entry- and advanced-level health e …

28.08.2026journal-article

Frontiers in Medicine

Genomic risk profiling in advanced maternal age: a Tamil Nadu prenatal study

Sujithra Appavu, Aruni Wilson Santhosh Kumar, Mukinkumar Sonai, Vinoth Appavu

Background Advanced maternal age (AMA; > = 35 years) is associated with increased fetal chromosomal risk and is an important indication for invasive prenatal diagnosis. This study evaluates karyotyping and chromosomal microarray analysis (CMA) findings among AMA pregnancies in Tamil Nadu, India. Methods In this prospective observational study, 2,200 pregnant women aged ≥35 years who underwent amniocentesis between July 2020 and June 2021 were enrolled. Conventional karyotyping was performed in all cases. CMA was …

28.08.2026journal-article

Frontiers in Medicine

Improvement in liver function and gross motor function after umbilical cord-derived mesenchymal stromal cell transplantation in a child with autoimmune hepatitis and concurrent cerebral palsy: a case report

Liem Thanh Nguyen, Huong Thu Le, Doan Van Ngo, Thi Kieu Trang Phan

Autoimmune hepatitis (AIH) is a complex immune-mediated liver disease of unknown origin that can rapidly progress to liver cirrhosis and end-stage liver failure. Standard treatment regimens typically involve immunosuppressive therapies, with most patients requiring lifelong maintenance. Recently, cell therapy has emerged as a potential therapeutic option for AIH. In this study, we report the case of a 2-year-old boy with type 2 autoimmune hepatitis and postcardiac arrest cerebral palsy who experienced clinical and …

28.08.2026journal-article

Journal of Experimental & Clinical Cancer Research

Overcoming immune checkpoint inhibitor-mediated T-cell exhaustion with a TCR β chain-directed selective dual T-cell activator

Shantel Angstadt, Lucas A. Horn, Kristen Fousek, Nika Rajabian, Haiyan Qin, Miriam M. Medina-Enriquez, Marcus D. Kelly, Nicole Hsiao-Sanchez, Thomas J. Meyer, Jacques Moisan, Madan Katragadda, Andrew Bayliffe, Zhen Su, Jeffrey Schlom, Claudia Palena

Abstract Background Resistance to immune checkpoint inhibition (ICI) using antibodies against the PD-1/PD-L1 axis remains a significant clinical challenge. Here, we report that combination of anti-PD-1 with a bifunctional fusion molecule, anti-TCRβ-IL-2, comprised of a monovalent Fab that binds and activates the T-cell receptor (TCR) through distinct variable beta (Vβ) chain residues and an IL-2 molecule, mediates robust anti-tumor control in the context of ICI resistance. Methods Syngeneic murine models with varyi …

28.08.2026journal-article

Public Understanding of Science

Apolitical referee or geopolitical actor? How artificial intelligence’s national-origin labels shape credibility in politicized science communication

Junyi Chen, Weixi Zeng, Yi Mou

Amid the politicization of science and the globalization of technological applications, does the national-origin label of artificial intelligence authors affect their perceived credibility? Drawing on the tension between artificial intelligence as an apolitical referee (machine heuristic) and artificial intelligence as a geopolitical actor like humans (social identity theory and computers-are-social-actors paradigm), two online experiments were conducted in China to examine the role of author type (human, artificia …

28.08.2026journal-article

BMC Medical Ethics

On the blind spot: ethical conflicts of health care professionals in addressing opioid diversion - a template study protocol for multinational qualitative research

Annette Binder, Sonja Mathes

Abstract Background Opioid diversion—the unauthorized redirection of prescription opioids—is a growing global concern with significant public health implications. While diversion can occur at many points in the supply chain, instances involving healthcare professionals (HCPs) are particularly complex, as they often occur within clinical settings and most often involve self-medication, substance use disorders among healthcare professionals, or peer dynamics. These cases raise not only legal and professional concerns …

28.08.2026journal-article

BMC Public Health

Epidemiological characteristics of hospitalized injury patients in a tertiary hospital of Guangxi Zhuang Autonomous Region, China: a retrospective single-center observational study

Chunxiu Yang, Jun Liang, Qingjiao Nong

Abstract Background Injury is a substantial public health issue that ranks among the primary causes of mortality and disability globally. This study aimed to analyze the epidemiological characteristics and types of injury among hospitalized patients through a single-center hospital-based retrospective study conducted in Guangxi Zhuang Autonomous Region in China. Methods A total of 15,869 hospitalized injury patient records were retrieved from the Hospital Information System (HIS) of the People’s Hospital of Guangxi …