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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

BMC Public Health

Epidemiological characteristics of hospitalized injury patients in a tertiary hospital of Guangxi Zhuang Autonomous Region, China: a retrospective single-center observational study

Chunxiu Yang, Jun Liang, Qingjiao Nong

Abstract Background Injury is a substantial public health issue that ranks among the primary causes of mortality and disability globally. This study aimed to analyze the epidemiological characteristics and types of injury among hospitalized patients through a single-center hospital-based retrospective study conducted in Guangxi Zhuang Autonomous Region in China. Methods A total of 15,869 hospitalized injury patient records were retrieved from the Hospital Information System (HIS) of the People’s Hospital of Guangxi …

28.08.2026journal-article

Physics in Medicine & Biology

Asymmetric spectral filtering for spectral-overlap suppression and differential phase-contrast reconstruction in spatial harmonic imaging

Hyunwoo Lim, Jonghyeok Lee, Seohee Han, Hyosung Cho

Abstract Objective. Spatial harmonic imaging (SHI) enables single-shot multi-contrast X-ray imaging, including dark-field imaging (DFI) and differential phase-contrast imaging (DPCI). However, spectral overlap between the first-harmonic band and adjacent spectra can produce wraparound artifacts and structural distortions. Asymmetric spectral filtering (ASF) has recently been proposed to suppress such artifacts in SHI-based DFI, but its effect on the first-harmonic signal and its applicability to DPCI remain unclear …

28.08.2026journal-article

Medicine

The platelet-to-high-density lipoprotein cholesterol ratio as a potential biomarker linking tobacco exposure to accelerated reproductive aging in women

Jie Liao, De Qiong, Dawa Zhuoma, Weiwei Ning, Da Ga, Silang Quncuo, Jing Jing, Lingxiu Li, Yalan Li, Xin Li, Bin Lv, Hengxi Chen

Female reproductive aging, commonly reflected by menopausal age and reproductive lifespan, is influenced by environmental exposures and metabolic health, and tobacco exposure has been associated with earlier menopause and shortened reproductive lifespan. Because this association may involve inflammatory activation and lipid-metabolic alterations, the platelet-to-high-density lipoprotein cholesterol ratio (PHR) may provide a useful composite marker for evaluating tobacco-related reproductive aging. We analyzed data …

28.08.2026journal-article

Medicine

Patient-reported outcomes of symptom burden and quality of life in patients with polycythemia vera and essential thrombocythemia in Korea

Yoorin Cho

This cross-sectional survey aimed to identify factors affecting quality of life (QoL) in patients with polycythemia vera (PV) and essential thrombocythemia (ET). Participants comprised 189 patients with PV or ET receiving outpatient treatment in Seoul. Data were collected using a structured questionnaire and analyzed using linear multiple regression analysis. Factors affecting the QoL in patients with PV or ET, including overall QoL, functional scales, and symptom experience, were fatigue, disease duration, numbnes …

28.08.2026journal-article

Journal of Applied Clinical Medical Physics

Clinical in‐vivo dosimetry for total skin electron therapy using gafchromic™ EBT4 film

Zhexuan Zhang, Lan Lu, Gregory M. M Videtic, Cherian Sheen, Ping Xia, Peng Qi

Abstract Background Total skin electron therapy (TSET) is a standard treatment for cutaneous T‐cell lymphoma. Due to the complex patient positioning and irregular body contours, robust in‐vivo dosimetry (IVD) is essential to verify dose uniformity. While thermoluminescent dosimeters (TLDs) are traditional standard, their utility is hindered by labor‐intensive, manual processing. Purposes This study evaluates the clinical implementation of a Gafchromic™ EBT4 film‐based IVD system integrated with a bespoke, open‐sour …

28.08.2026journal-article

British Journal of Health Psychology

Acceptability, perceived outcomes and underlying mechanisms of a professionally led support group intervention for women with breast cancer using a qualitative method approach

Andreia Soares, Diogo Carreiras, Bruna Veloso, Ana Pereira, Priscyla Costa, Mind Project Team, Helena Moreira, Inês A. Trindade

Abstract Objectives Breast cancer (BC) remains the most diagnosed cancer among women worldwide and its growing survivorship population faces numerous long‐term physical and psychological challenges. Cancer support groups emerge as promising interventions to promote comprehensive management of the disease and survivorship needs, emotional well‐being and social connection. Accordingly, this study aimed to analyse the acceptability and perceived impact of the Mind Support Group (MSG), a professionally led support grou …

28.08.2026journal-article

BMC Pulmonary Medicine

Impact of CPAP and ventilator system resistance on respiratory effort in healthy volunteers

Simon Lindner, Lena Doerflinger, Luisa S. Drotleff, Burcu Link, Benjamin Neetz, Julia D. Michels-Zetsche, Felix J. F. Herth, Daniel Duerschmied, Simone Britsch

Abstract Introduction Continuous positive airway pressure (CPAP) is widely used for the treatment of acute and chronic respiratory failure and inspiratory support pressure (ΔP insp ) can be added to achieve non-invasive ventilation (NIV). We performed a physiological study to determine the effect of CPAP and inspiratory support pressure on respiratory effort measured by esophageal tidal swings in healthy volunteers. Methods Esophageal tidal swings were measured in spontaneously breathing, healthy volunteers undergo …

28.08.2026journal-article

Japanese Journal of Clinical Oncology

Darolutamide-based triplet therapy versus androgen receptor pathway inhibitor-based doublet therapy for metastatic castration-sensitive prostate cancer: a real-world analysis using the TriNetX database

Yoichiro Tohi, Yuri Kitadani, Takuma Kato, Shunsuke Nakamura, Naoya Kani, Iori Matsuda, Kana Kohashiguchi, Yohei Abe, Hirohito Naito, Homare Okazoe, Rikiya Taoka, Fumiaki Mikami, Mikio Sugimoto

Abstract Background Currently, there are no large cohort studies comparing the clinical outcomes of triplet therapy with those of androgen receptor pathway inhibitor (ARPI)-based doublet therapy for patients with metastatic castration-sensitive prostate cancer (mCSPC) representing real-world practice. Therefore, the present study aimed to compare whether triplet or doublet therapy is more effective in patients with mCSPC. Methods This large-scale retrospective cohort study used TriNetX electronic medical record dat …

28.08.2026journal-article

PLOS One

Cognitive load and individual differences as drivers of health-related misinformation: A signal detection approach

Guillermo Puebla, Rodrigo Ferrer-Urbina, Daniel Pérez-Zapata, Karina Alarcón-Castillo, Geraldy Sepúlveda-Páez, Herman Elgueta

The global spread of health-related misinformation during the COVID-19 pandemic has highlighted the need to understand the psychological mechanisms that make individuals susceptible to health-related misinformation. This study examined the impact of cognitive load and individual differences on susceptibility to COVID-19 misinformation using a Signal Detection Theory framework. A sample of 634 university students evaluated true and false COVID-19 headlines under working memory load and no-load conditions, while also …

28.08.2026journal-article

The Journal of Medicine, Law & Public Health

Malaria in Pregnancy: Knowledge, Attitudes, Perceptions, and Preventive Practices Among Pregnant Women in Okitipupa, Ondo State, Nigeria

Adeyemi Ogedengbe Omoge, Olabode Oluyinka Kayode

Background: Malaria in pregnancy (MiP) remains a major public health concern in sub-Saharan Africa, contributing substantially to maternal and neonatal morbidity and mortality. Understanding and enhancing pregnant women's knowledge, attitudes, perceptions, and preventive practices in this regard is essential for improving malaria prevention and control. Objectives: This study assessed the knowledge, attitudes, and perceptions (KAP), as well as preventive practices regarding MiP among pregnant women attending antena …

28.08.2026journal-article

International Journal of Environmental Research and Public Health

Problems Related to Social Media Use in Finnish Adolescents: Gender Differences and Correlates

Terhi Mustonen, Kirsimarja Raitasalo, Sari Castrén

Background: Problematic social media use among adolescents has emerged as a growing public health concern. This study examined gender differences in problems related to social media use and their behavioural, psychosocial, family-related, and school-related correlates among Finnish adolescents. Methods: In this cross-sectional study, binary logistic regression analyses were conducted using data from the Finnish sample of the 2024 European School Survey Project on Alcohol and Other Drugs (ESPAD), including 3293 adol …

28.08.2026journal-article

Frontiers in Child and Adolescent Psychiatry

Co-designing and piloting adolescent-adapted social rhythm therapy for young people with unipolar and bipolar depression: a mixed-methods feasibility case series

Gonzalo Salazar de Pablo, Claudia Aymerich, Zahra Kamran, Cecilia Sanjuan-Ortiz, Nuria Laherran-Cantera, Shantal Zeb, Eleonora Armyra, Allan H. Young, Aditya Sharma, Cornelius Ani, Manasi Kumar, Holly A. Swartz

Objective Depressive and bipolar disorders commonly emerge during adolescence and are associated with disturbances in sleep, daily routines and social rhythms, as well as functional impairment. Social Rhythm Therapy (SRT) targets these processes. However, adult-derived rhythm protocols do not adequately reflect adolescents’ school and family schedules, developmental autonomy, social and digital routines, or preferences regarding monitoring. Direct youth co-design is therefore needed to improve developmental fit, en …

28.08.2026journal-article

Health Affairs Scholar

Primary Care Physician Characteristics and Potentially Inappropriate Medications in Older Adults

Yuki Tatsuno, Catherine A Sarkisian, John N Mafi, Kei Kitajima, Daichi Sato, Yusuke Tsugawa, Atsushi Miyawaki

Abstract Background Potentially inappropriate medications (PIMs) are a growing public health concern. While research in North America suggests physician characteristics were associated with PIM prescription, their generalizability to other countries remains understudied. Methods We conducted a cross-sectional study using a nationwide electronic health record database of primary care clinics in Japan. We analyzed patients aged ≥75 years who visited solo-practice physicians at least quarterly during October 2022 to S …

28.08.2026journal-article

INTERNATIONAL JOURNAL OF PUBLIC HEALTH RESEARCH AND DEVELOPMENT

PUBLIC HEALTH AND ENVIRONMENTAL IMPACT OF HEAVY METALS IN BOTTOM COAL ASH

I OshatuyiI, R. A Ibrahim, F D Egwuje, X H I Abdullahi H I

There have been great public health and environment concerns on the concentration of heavy metals especially those present in bottom coal ash as they could have impact on the well-being of humans and other living things. This study examined the toxicity and utility of heavy metals in bottom coal ash and their public health and environment impacts by evaluating the heavy metal concentration, toxicity, and utility of bottom coal ash. The concentration of heavy metals was determined using an atomic absorption spectrom …

28.08.2026journal-article

INTERNATIONAL JOURNAL OF PUBLIC HEALTH RESEARCH AND DEVELOPMENT

AWARENESS OF HEALTH RISKS OF DIRTY COOKING FUELS AND DEMAND FOR COOKING FUELS IN JOS METROPOLITAN CITY, NIGERIA

Vonke Juliana Dickson, Yerima Ishaya Jabil, Philip Enyinnaya Dickson, Faith Onechojo Etuh, Onyinnyechi Josephine Onuoha

This paper investigated the influence of the awareness of health risks of ‘dirty’ cooking fuels on the demand for cooking fuels among households in Jos metropolitan city. The study adopted qualitative research design. Key Informant Interviews (KIIs) were conducted with 16 households’ decision makers. Results of the study showed that households in Jos metropolitan city use a combination of cooking fuels: liquefied petroleum gas, which is the primary cooking fuel, charcoal and firewood, which are secondary. Convenien …

28.08.2026journal-article

Borneo Nursing Journal (BNJ)

Efektivitas Triple Maneuver terhadap Peningkatan Saturasi Oksigen pada Pasien Pasca Anestesi Umum di Ruang Pemulihan RS PKU Muhammadiyah Yogyakarta

Berliyana Felanueva, Nia Handayani, Endah Tri Wulandari

Pasien pasca anestesi umum berisiko mengalami penurunan saturasi oksigen akibat depresi pernapasan, relaksasi otot faring, dan obstruksi jalan napas sehingga diperlukan intervensi untuk mempertahankan kepatenan jalan napas dan mengoptimalkan oksigenasi. Penelitian ini bertujuan mengetahui efektivitas Triple Maneuver terhadap peningkatan saturasi oksigen pada pasien pasca anestesi umum di ruang pemulihan RS PKU Muhammadiyah Yogyakarta. Penelitian menggunakan desain quasi-experiment dengan pretest-posttest control gr …

28.08.2026journal-article

Clinical Genetics

Recurrent Sterile Polyserositis Reveals an Underrecognized Autoinflammatory Phenotype in MECP2 Duplication Syndrome

Danielle Mendonca, Matt S. Zinter, Sunjay R. Devarajan, Jason Boehme, Bernhard Suter, Mirjana Maletic‐Savatic, Eyal Muscal, Davut Pehlivan

ABSTRACT MECP2 duplication syndrome (MDS) is a rare neurogenetic disorder characterized by neurodevelopmental delay, epilepsy, gastrointestinal dysfunction, and frequent infections. The broader spectrum of immune dysregulation remains poorly understood. We retrospectively reviewed four MDS patients with recurrent sterile polyserositis across multiple centers, analyzing clinical presentation, laboratory findings, treatment responses, and outcomes. All patients developed recurrent pleural and/or pericardial effusions …

28.08.2026journal-article

Health Research Journal of Indonesia

Paparan Media Digital dan Perilaku Seksual Berisiko pada Remaja di SMK Kesehatan di Surakarta

Atur Semartini, Lilik Ariyanti

Perilaku seksual berisiko pada remaja dapat menimbulkan dampak negatif pada kesehatan dan kehidupan remaja. Salah satu faktor yang memicu perilaku seksual pranikah pada remaja adalah keberadaan media digital. Media digital memungkinkan remaja memperoleh berbagai informasi dengan cepat, salah satunya informasi dan konten terkait pornografi dan seksualitas. Penelitian ini bertujuan menganalisis hubungan paparan media digital dan perilaku seksual berisiko pada siswa SMK Kesehatan di Surakarta. Penelitian cross section …

28.08.2026journal-article

African Journal of Primary Health Care & Family Medicine

Cardiometabolic risk profile and associated factors among adults with type 2 diabetes in a primary health care clinics in North Central Nigeria

Innocent N. Okonkwo, Maryanna Idoh, Ezra O. Agbo, Edwin N. Okafor

Background: Cardiometabolic abnormalities substantially increase morbidity among individuals with type 2 diabetes mellitus (T2DM), particularly in primary health care (PHC) settings. In Nigeria, evidence on comprehensive metabolic risk profiling beyond glycaemic control remains limited. Aim: To determine the cardiometabolic risk profile and identify factors associated with adverse cardiometabolic outcomes among adults with T2DM. Setting: The study took place at government-owned PHC facilities in Makurdi, Benue Stat …

28.08.2026journal-article

Journal of Translational Medicine

Transcriptomic profiling of lineage transformation and actionable therapy opportunities in EGFR-mutant non-small cell lung cancer evolving to small cell lung cancer

Hui Yu, Meichen Li, Xiaodie Li, Mingjie Yu, Yin Pan, Jingping Yun, Likun Chen

Abstract Background Neuroendocrine transformation of epidermal growth factor receptor-mutant lung adenocarcinoma (EGFR m LUAD) represents a significant mechanism underlying acquired resistance to EGFR tyrosine kinase inhibitors (TKIs). This histological transformation lacks effective treatments. We comprehensively discussed the treatments of transformed small cell lung cancer (T-SCLC) and analyzed the transcriptomic profile of EGFR m LUAD and paired T-SCLC, aiming to understand the immune landscape of this T-SCLC s …

28.08.2026journal-article

JAMA Health Forum

Administrative Burden Documented in Medicaid Care Coordination

Sanjay Basu, Aaron Baum, Kiiera Robinson, Rajaie Batniji

Importance Administrative burdens, the time, effort, and stress of navigating bureaucratic requirements, impede Medicaid beneficiaries and persist even when care is obtained, yet their frequency and patient time costs are largely invisible in claims data. Objective To measure administrative burdens documented in Medicaid care coordination notes by type, quantify the patient time costs they entail at multiple wage valuations, and characterize differences by race and ethnicity. Design, Setting, and Participants Retro …

28.08.2026journal-article

International Journal of Social Sciences and Public Administration

Earning Trust through Performance: The Initiation Mechanism of Collaborative Governance in Low-Trust Communities

Yijia Wu

In low-trust communities, residents often expect visible service improvements before paying fees, whereas property management companies require stable revenue expectations before increasing investment. This mutual wait-and-see stance creates a first-mover dilemma. Drawing on the fiduciary property management reform in XH Residential Community in Chengdu, this study uses semi-structured interviews, participant observation, and document analysis to examine how institutional transparency is converted into performance- …

28.08.2026journal-article

Sakarya Üniversitesi Holistik Sağlık Dergisi

Can Artificial Intelligence Replace Nursing? Examining Nursing Students’ Attitudes, Anxiety, and Dependency

Eren Sarıtaş, Pınar Çiçekoğlu Öztürk

Objective: As the growing use of artificial intelligence in healthcare creates both new opportunities and emerging concerns for nursing practice, this study aimed to examine nursing students’ attitudes toward artificial intelligence and to explore the extent to which AI-related anxiety and technological dependency predict these attitudes.Methods: A descriptive, cross-sectional, and correlational design was employed with a sample of 373 nursing students studying at a public university in Türkiye. The data were colle …

28.08.2026journal-article

Journal of Clinical Medicine

Soluble CLEC-2 as an Emerging Biomarker of In Vivo Platelet Activation

Katsue Suzuki-Inoue, Makyo Ueda, Toshiaki Shirai, Nagaharu Tsukiji, Tomoyuki Sasaki

Platelet activation plays a central role in arterial thrombosis, thromboinflammation, and microvascular injury. Conventional platelet function tests evaluate platelet responsiveness to exogenous agonists ex vivo but do not directly reflect in vivo platelet activation. Although several soluble platelet-derived molecules, including platelet factor 4 (PF4), β-thromboglobulin (β-TG), soluble P-selectin, soluble CD40 ligand, glycocalicin, and soluble glycoprotein (GP) VI, have been investigated as in vivo platelet activ …