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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
14.08.2026journal-article

Polymer Composites

Hygrothermal Aging and Failure Mechanism of Glass Fiber Reinforced Polyurethane Composite Frames for Offshore Applications

Yanping Huang, Yi Liu, Qingfa Meng, Xiaogang Zhu, Zhengyang Zou

ABSTRACT The durability of glass fiber reinforced polyurethane (GFRPU) composites under harsh marine environments is critical for offshore photovoltaic applications. This paper investigates the hygrothermal aging behavior and failure mechanisms of GFRPU composites by pressure cooking test (PCT) at 121°C and 100% RH for up to 240 h. Moisture absorption increases linearly to 2.42% after 240 h without reaching saturation, deviating from Fickian behavior due to diffusion‐damage coupling. Mechanical properties show a tw …

14.08.2026journal-article

Bioengineering

Deep Learning-Based Temporal Gait Analysis Using a Smartphone IMU in Older Adults with and Without Non-Specific Low Back Pain

Gerome Vivar, Shivam Singh, Tobias Bea, Christian Saal, Victor Munoz-Martel, Lutz Schega

Accurate gait event detection using inertial measurement units (IMUs) is essential for temporal gait analysis, but frame-level detection is challenged by sparse initial contact (IC) and foot-off (FO) events. This study evaluated recurrent neural network architectures and training strategies for simultaneous IC and FO detection using a single shank-mounted smartphone IMU. The internal dataset included 28 healthy older adults and 18 individuals with non-specific low back pain (NSLBP). Temporal label expansion substan …

14.08.2026journal-article

Revista Digital Universitaria

Cuando el corazón afecta la mente: la conexión entre hipertensión y Alzheimer

Elivier García González, Gerardo Iván Gálvez Ortega, José Eduardo Huerta Lépez

La hipertensión arterial y el Alzheimer son dos condiciones que, a simple vista, parecen no tener nada en común. Una afecta el corazón y los vasos sanguíneos; la otra la memoria y funciones mentales. Sin embargo, recientes hallazgos científicos revelan una conexión más profunda entre ambas. Este artículo explora cómo la presión arterial elevada, más allá de sus efectos cardiovasculares, puede dañar lentamente el cerebro al crear un entorno propicio para el desarrollo del Alzheimer. Además, se abordan los procesos f …

14.08.2026journal-article

Health Psychology Research

Development and external validation of an interpretable machine learning model for depressive symptom screening in Chinese adults aged 50 years or older with diabetes

Siheng Ma, Qilong Wang, Rui Qi, Huaning Wang, Min Cai

Background: Depressive symptoms are common among people with diabetes and may impair self-management and quality of life. Objective: This study aimed to develop and externally validate an interpretable machine-learning model for depressive symptom screening in Chinese adults aged 50 years or older with diabetes and translate it into an online assessment tool. Methods: Participants with diabetes from Round 4 of the China Health and Retirement Longitudinal Study (n = 2,187) were randomly divided into training and int …

14.08.2026journal-article

Working with Older People

When compassion meets complexity: managing the psychological contract to reduce turnover in complex elder adult care

Samyak Shah, Sunaina Chetan Kuknor

Purpose This study aims to address why standard human resource (HR) retention strategies fail to reduce staff turnover in elder adult care settings. The introduction of caseload complexity (the coexistence of multiple, interacting physical, cognitive and social needs in residents) explores the conditions for how the psychological contract breach happens in workers. Thereby, reframing turnover as a relational problem, rather than a transactional one. Design/methodology/approach A conceptual methodology is adopted, s …

14.08.2026journal-article

Medicine

Gut microbiota alterations and their correlation with constipation in older adults with Alzheimer’s disease or mild cognitive impairment

Kai-Yong Huang, Yi-Yu Wei, Shu-Ting Zhang, Liu-Chun He, Jing Zhou, Lan-Shu Zhou, Hua-Bin Su, Guo-Dong Lu

Previous studies have suggested a link between gut microbiota, constipation and Alzheimer’s disease (AD) as well as mild cognitive impairment (MCI). In this study, we aimed to investigate the changes in the gut microbiota and their relationship with constipation in patients with AD and MCI. A total of 90 participants (30 with AD, 30 with MCI, and 30 normal controls) were recruited from the community-based Nanning Community Elderly Population cohort. We collected fresh fecal samples for analysis and compared the dif …

14.08.2026journal-article

The International Journal of Aging and Human Development

The Shadowy Side of Aging: The Determining Role of Depression in the Development of Frailty

Tuba Geçdi, Emine Derya İster

Frailty and depression are geriatric syndromes commonly seen in older adults that negatively affect quality of life and functional status. This study examined the levels of frailty and depression and the relationship between them in 159 older adults who visited three family health centers. Data were collected using the Edmonton Frailty Scale and Geriatric Depression Scale. Depression was detected in 22.6% of participants, and frailty in 33.4%. Frailty showed a significant relationship with marital status, education …

14.08.2026journal-article

ACS Omega

Topical Menaquinone-7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study

He Huang, Ruijing Wei, Chunxiao Xu, Chen Liu, Shilan Zhao, Yanan Li, Meijing Wang

Abstract Mitochondrial dysfunction contributes to skin aging by limiting cellular energy supply, shifting redox balance, and amplifying oxidative injury, which together favor extracellular matrix breakdown and loss of tissue mechanics. Vitamin K2 (menaquinone-7; MK-7) has been proposed to support mitochondrial electron transport, yet its bioenergetic activity in the skin and its effects on aging-related outcomes remain insufficiently characterized. To evaluate whether MK-7 can improve mitochondrial bioenergetics in …

14.08.2026journal-article

Insects

Insect-Derived Anti-Aging Bioresources: Current Status, Bottlenecks, and Future Directions

Minghui Zhao, Weina Wang, Hongyu Lai, Lixin Zhou, Qi Liao, Jinxin Liu, Hongning Liu, Miao Ouyang, Gang Ren, Zishu Dong

As the global population ages rapidly, demand for safe and effective strategies to promote healthy aging grows markedly. Natural bioactive compounds, with favorable biosafety profiles and multi-target regulatory properties, have become a core focus in developing anti-aging functional foods and nutraceuticals. Amid the search for novel sustainable bioresources, insects emerge as promising anti-aging candidates for their rich species diversity, scalable production, low environmental footprint, and abundant unique bio …

14.08.2026journal-article

The Gerontologist

Older Adults’ End-of-Life Care: Are Retrospective Assessments Patterned by Proxy Relationship to Decedent?

Kafayat Mahmoud, Deborah Carr

Abstract Background and Objectives Understanding the quality of older adults’ end-of-life care is essential for informed decision-making and practitioner accountability. However, retrospective appraisals provided by proxies may be shaped by their relationship to the decedent. Failure to adjust for proxy relationship status may generate misleading characterizations of end-of-life care patterning. We examine how proxy reporters (spouse, daughter, son, other relative, other non-relative, paid caregiver) differ in thei …

14.08.2026journal-article

Journal of Cancer Survivorship

The effect of health behaviour interventions on alcohol consumption among people living with cancer: a systematic review

Manuela Beaty, Wei-Hong Liu, Patsy Yates, Kim Alexander

Abstract Purpose This systematic review synthesises data relating to the effectiveness of behavioural interventions aimed at reducing alcohol consumption among people living with cancer. Methods Five databases were systematically searched for randomised controlled trials (RCTs) published between January 2000 and April 2025 that reported behavioural interventions addressing alcohol consumption among people living with cancer. Evidence was assessed using the Cochrane Risk-of-Bias tool. Meta-analysis was not feasible …

14.08.2026journal-article

Revista ft

Doença renal crônica em cadela geriátrica associada à neoplasia mamária e alterações endócrinas: relato de caso

Vitória Silva Santos, Maysa Mayara de Miranda Falcão, Maria Eduarda Carvalho Mesquita, Marcos Vinícius Lebrego Nascimento, Maria Audileia da Silva Teixeira, Giselle Almeida Couceiro

Chronic kidney disease (CKD) is a progressive and irreversible condition commonly observed in geriatric dogs, often associated with comorbidities that worsen prognosis. This study reports the case of a geriatric female dog with a history of hormonal alterations and mammary neoplasia associated with CKD. The animal presented clinical signs such as polyuria, polydipsia, and marked weight loss. Laboratory findings revealed azotemia, anemia, and systemic arterial hypertension. Abdominal ultrasonography showed findings …

14.08.2026journal-article

Frontiers in Oral Health

Constructing self-rated oral health among disadvantaged older African Americans

Mark R. Luborsky, Candace Ziglor, Divesh Byrappagari, Jocie Osika, Kimberly Shay, Judith Jones

Poor oral health care is prevalent among minority, disadvantaged, and older populations despite being readily treatable by effective, low-technology, low-cost interventions for prevention and early care. Oral health is a recognized priority ( 1 , 2 ) in the goals set by the “Oral Health in Healthy People 2030″ ( 3 ) and the World Health Organization's call to for universal oral health coverage ( 4 ). However, many challenges exist, including inadequate awareness, knowledge, and access, particularly among disadvanta …

14.08.2026journal-article

Current Oncology

Prognostic Value of Immunonutritional Status and Radiologic Muscle Mass in Older Patients Receiving Immune Checkpoint Inhibitors: A Real-World Study

Hülya Ertaş, Burcu Caner, Sibel Oyucu Orhan, Buket Şahin Çelik, Işıl Yüceışık, Yasemin Koç

Background: Identifying biomarkers for biological vulnerability in older patients with cancer remains challenging. We evaluated psoas muscle index (PMI) and immunonutritional indices’ association with toxicity and overall survival (OS) in patients ≥ 65 years receiving immune checkpoint inhibitors (ICIs). Methods: This retrospective study included 104 patients. Baseline sarcopenia was assessed via CT-derived PMI at the L3 level. Immunonutritional status was evaluated using the Prognostic Nutritional Index (PNI). Pri …

14.08.2026journal-article

Advances in Translational Research

Nuclear transcriptional regulation of mitochondria in the aging heart: From mechanisms to targeted therapeutic strategies

Pankaj Patyal, Gohar Azhar, Jeanne Y. Wei

Abstract The concept of mitochondrial functional decline in the aging heart was proposed decades ago, however, the underlying mechanisms are still not well established. Now more than ever, emerging research on cardiac mitochondria is revealing how these essential organelles play a pivotal role in maintaining cardiac health through transcriptional regulation of mitochondrial function during aging. Because the majority of mitochondrial proteins are encoded by nuclear genes, transcriptional regulation within the nucle …

14.08.2026journal-article

Medicine

The role of mitochondrial fusion protein 2 in regulating ER stress in premature placental aging

Dandan Sun, Ling Ai, Ping Xu, Jiawei Zhou, Lili Xue

Advanced maternal age (AMA) is associated with an increased risk of adverse perinatal outcomes, which may be attributed to premature placental aging. Previous studies have demonstrated that mitochondrial fusion protein 2 (Mfn2) plays a critical role in aging-related neurodegenerative disorders, metabolic diseases, and vascular pathologies. However, its expression in AMA pregnancies and its impact on placental function remain poorly understood. This study aimed to investigate the expression patterns of Mfn2 in place …

14.08.2026journal-article

Scientific Reports

Physics-aligned causal inference of driving styles on electric vehicles battery aging

Hao Cheng, Zhongwei Gu, Wangqiang Gao

Abstract Lithium-ion batteries (LIBs) remain the core service life bottleneck of electric vehicles (EVs), and driving style is a critical human factor dominating EV battery degradation as assessed via aging proxy indicators and semi-empirical model predictions. Existing studies mostly focus on correlation analysis between driving behavior and aging, suffering from unphysical black-box models and unreliable causal identification due to uncontrolled confounding factors. This paper proposes a physics-aligned causal in …

14.08.2026journal-article

Frontiers in Public Health

Slow public health: a temporal-relational framework for migration and aging in the Global South

Miroslava Tokovska, Jozef Suvada

Population aging and migration represent two of the most profound demographic transformations shaping the Global South. Conventional public health approaches have typically relied on standardized interventions and measurable outcomes, yet such frameworks often fail to capture the temporal, relational, and contextual dimensions affecting aging populations. This perspective introduces “Slow Public Health” as a temporal-relational framework for public health practice in migration and aging contexts. Building on the Sl …

14.08.2026journal-article

Frontiers in Medicine

From skin aging biomarkers to precision esthetic longevity: a translational diagnostic framework

Sarit Cohen, Dominik Thor

Skin aging is commonly evaluated through visible phenotype, clinical grading, and photographic documentation, yet these approaches incompletely capture the biological mechanisms that shape tissue quality, regenerative capacity, and long-term response to intervention. Recent advances in longevity science, including skin-specific epigenetic clocks, molecular profiling, functional tissue assessment, imaging technologies, and artificial intelligence-derived digital phenotyping create an opportunity to redefine esthetic …

14.08.2026journal-article

International Journal of Educational Teaching and Research

Discussion on the Sports and Exercise Rehabilitation Majors in New Zealand Universities and their Relationships with Aging Society

Man Li, Xu Dai

With the increase in the number of older people around the world, problems in their health have attracted more attention from society. Sports and exercise rehabilitation play an essential role in improving the physical fitness, boosting the mental health and overall quality of life of older people, and thus have gradually become important ways to address the health problems of an aging society. As the main institutions for knowledge innovation and talent cultivation, universities in New Zealand have achieved good r …

14.08.2026journal-article

Journal of Manufacturing and Materials Processing

Thermal Aging and Geometry-Driven Changes in Strength of 3D-Printed Polymers

Mohammad Reza Khosravani, Payam Soltani, Morteza Mohammadzaheri, Majid R. Ayatollahi

The benefits of additive manufacturing (AM, i.e., 3D printing) have made it one of the most widely used and favored production techniques across a variety of industries. In the current study, the influence of geometry and thermal aging on the mechanical strength of AMed parts has been investigated. In this context, specimens based on fused deposition modeling were printed using polylactic acid material. The specimens with three distinct geometries were created and analyzed since the geometry of AMed parts affects t …

14.08.2026journal-article

Revista Chilena de Rehabilitación y Actividad Física

Efectividad de la metodología de entrenamiento 1x2x3 sobre la fuerza, velocidad de la marcha y el equilibrio valorado sobre el test sppb en personas mayores de la comunidad

Boris Cariaga Araneda

ABSTRACT Objective: To evaluate the effectiveness of the 1x2x3 training methodology on muscle strength, walking speed, and functional balance in community-dwelling older adults, using the Short Physical Performance Battery (SPPB). Methodology: A longitudinal quasi-experimental study involving 31 participants (aged ≥65 years), divided into an experimental group (n=16) and a control group (n=15). The experimental group underwent an 8-week 1x2x3 training program, while the control group received a brief educational se …

14.08.2026journal-article

Frontiers in Public Health

Vulnerability of older adults to heatwaves: the Barcelona case

Blanca Arellano, Josep Roca, Carina Serra, Dolors Martínez

Heatwaves are becoming more frequent, intense, and persistent as a result of global warming, posing a growing public health challenge in Mediterranean cities. In Barcelona, this process is characterized by a pronounced increase in nighttime temperatures, amplified by the urban heat island effect and by a rapidly aging population, which together increase vulnerability to heat-related health impacts. This study aims to assess the effects of high temperatures on mortality in Barcelona, with a particular focus on older …

14.08.2026journal-article

Frontiers in Aging Neuroscience

Restoring anticipatory control through cognitive–motor dual-task training improves emotional and executive function in frail older adults

Luca Boccacci, Martina Scalia, Riccardo Borzuola, Valentina Camomilla, Domenico Campagna, Andrea Casella, Imma Ceriello, Natalie Ferrulli, Margherita Filosa, Chiara Fossati, Federica Galli, Andrea Macaluso, William Manzon, Camilla Panacci, Martina Parrella, Fabio Pigozzi, Sabrina Pitzalis, Franco Pio Siciliano, Arnaldo Zelli, Francesco Di Russo

Background Aging-related frailty is increasingly recognized as a multidimensional condition involving impairments in cognitive, emotional, and motor domains. Traditional interventions often fail to capture the complexity of real-world functioning, highlighting the need for more ecologically valid approaches. Objectives This study investigated the effects of a structured Cognitive–Motor Dual-Task Training (CMDT) protocol, incorporating alternating bilateral stimulation (BAS), on emotional regulation, executive funct …