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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
14.08.2026journal-article

The Gerontologist

Older Adults’ End-of-Life Care: Are Retrospective Assessments Patterned by Proxy Relationship to Decedent?

Kafayat Mahmoud, Deborah Carr

Abstract Background and Objectives Understanding the quality of older adults’ end-of-life care is essential for informed decision-making and practitioner accountability. However, retrospective appraisals provided by proxies may be shaped by their relationship to the decedent. Failure to adjust for proxy relationship status may generate misleading characterizations of end-of-life care patterning. We examine how proxy reporters (spouse, daughter, son, other relative, other non-relative, paid caregiver) differ in thei …

14.08.2026journal-article

Journal of Cancer Survivorship

The effect of health behaviour interventions on alcohol consumption among people living with cancer: a systematic review

Manuela Beaty, Wei-Hong Liu, Patsy Yates, Kim Alexander

Abstract Purpose This systematic review synthesises data relating to the effectiveness of behavioural interventions aimed at reducing alcohol consumption among people living with cancer. Methods Five databases were systematically searched for randomised controlled trials (RCTs) published between January 2000 and April 2025 that reported behavioural interventions addressing alcohol consumption among people living with cancer. Evidence was assessed using the Cochrane Risk-of-Bias tool. Meta-analysis was not feasible …

14.08.2026journal-article

Revista ft

Doença renal crônica em cadela geriátrica associada à neoplasia mamária e alterações endócrinas: relato de caso

Vitória Silva Santos, Maysa Mayara de Miranda Falcão, Maria Eduarda Carvalho Mesquita, Marcos Vinícius Lebrego Nascimento, Maria Audileia da Silva Teixeira, Giselle Almeida Couceiro

Chronic kidney disease (CKD) is a progressive and irreversible condition commonly observed in geriatric dogs, often associated with comorbidities that worsen prognosis. This study reports the case of a geriatric female dog with a history of hormonal alterations and mammary neoplasia associated with CKD. The animal presented clinical signs such as polyuria, polydipsia, and marked weight loss. Laboratory findings revealed azotemia, anemia, and systemic arterial hypertension. Abdominal ultrasonography showed findings …

14.08.2026journal-article

Frontiers in Oral Health

Constructing self-rated oral health among disadvantaged older African Americans

Mark R. Luborsky, Candace Ziglor, Divesh Byrappagari, Jocie Osika, Kimberly Shay, Judith Jones

Poor oral health care is prevalent among minority, disadvantaged, and older populations despite being readily treatable by effective, low-technology, low-cost interventions for prevention and early care. Oral health is a recognized priority ( 1 , 2 ) in the goals set by the “Oral Health in Healthy People 2030″ ( 3 ) and the World Health Organization's call to for universal oral health coverage ( 4 ). However, many challenges exist, including inadequate awareness, knowledge, and access, particularly among disadvanta …

14.08.2026journal-article

Current Oncology

Prognostic Value of Immunonutritional Status and Radiologic Muscle Mass in Older Patients Receiving Immune Checkpoint Inhibitors: A Real-World Study

Hülya Ertaş, Burcu Caner, Sibel Oyucu Orhan, Buket Şahin Çelik, Işıl Yüceışık, Yasemin Koç

Background: Identifying biomarkers for biological vulnerability in older patients with cancer remains challenging. We evaluated psoas muscle index (PMI) and immunonutritional indices’ association with toxicity and overall survival (OS) in patients ≥ 65 years receiving immune checkpoint inhibitors (ICIs). Methods: This retrospective study included 104 patients. Baseline sarcopenia was assessed via CT-derived PMI at the L3 level. Immunonutritional status was evaluated using the Prognostic Nutritional Index (PNI). Pri …

14.08.2026journal-article

Advances in Translational Research

Nuclear transcriptional regulation of mitochondria in the aging heart: From mechanisms to targeted therapeutic strategies

Pankaj Patyal, Gohar Azhar, Jeanne Y. Wei

Abstract The concept of mitochondrial functional decline in the aging heart was proposed decades ago, however, the underlying mechanisms are still not well established. Now more than ever, emerging research on cardiac mitochondria is revealing how these essential organelles play a pivotal role in maintaining cardiac health through transcriptional regulation of mitochondrial function during aging. Because the majority of mitochondrial proteins are encoded by nuclear genes, transcriptional regulation within the nucle …

14.08.2026journal-article

Medicine

The role of mitochondrial fusion protein 2 in regulating ER stress in premature placental aging

Dandan Sun, Ling Ai, Ping Xu, Jiawei Zhou, Lili Xue

Advanced maternal age (AMA) is associated with an increased risk of adverse perinatal outcomes, which may be attributed to premature placental aging. Previous studies have demonstrated that mitochondrial fusion protein 2 (Mfn2) plays a critical role in aging-related neurodegenerative disorders, metabolic diseases, and vascular pathologies. However, its expression in AMA pregnancies and its impact on placental function remain poorly understood. This study aimed to investigate the expression patterns of Mfn2 in place …

14.08.2026journal-article

Scientific Reports

Physics-aligned causal inference of driving styles on electric vehicles battery aging

Hao Cheng, Zhongwei Gu, Wangqiang Gao

Abstract Lithium-ion batteries (LIBs) remain the core service life bottleneck of electric vehicles (EVs), and driving style is a critical human factor dominating EV battery degradation as assessed via aging proxy indicators and semi-empirical model predictions. Existing studies mostly focus on correlation analysis between driving behavior and aging, suffering from unphysical black-box models and unreliable causal identification due to uncontrolled confounding factors. This paper proposes a physics-aligned causal in …

14.08.2026journal-article

Frontiers in Public Health

Slow public health: a temporal-relational framework for migration and aging in the Global South

Miroslava Tokovska, Jozef Suvada

Population aging and migration represent two of the most profound demographic transformations shaping the Global South. Conventional public health approaches have typically relied on standardized interventions and measurable outcomes, yet such frameworks often fail to capture the temporal, relational, and contextual dimensions affecting aging populations. This perspective introduces “Slow Public Health” as a temporal-relational framework for public health practice in migration and aging contexts. Building on the Sl …

14.08.2026journal-article

Frontiers in Medicine

From skin aging biomarkers to precision esthetic longevity: a translational diagnostic framework

Sarit Cohen, Dominik Thor

Skin aging is commonly evaluated through visible phenotype, clinical grading, and photographic documentation, yet these approaches incompletely capture the biological mechanisms that shape tissue quality, regenerative capacity, and long-term response to intervention. Recent advances in longevity science, including skin-specific epigenetic clocks, molecular profiling, functional tissue assessment, imaging technologies, and artificial intelligence-derived digital phenotyping create an opportunity to redefine esthetic …

14.08.2026journal-article

International Journal of Educational Teaching and Research

Discussion on the Sports and Exercise Rehabilitation Majors in New Zealand Universities and their Relationships with Aging Society

Man Li, Xu Dai

With the increase in the number of older people around the world, problems in their health have attracted more attention from society. Sports and exercise rehabilitation play an essential role in improving the physical fitness, boosting the mental health and overall quality of life of older people, and thus have gradually become important ways to address the health problems of an aging society. As the main institutions for knowledge innovation and talent cultivation, universities in New Zealand have achieved good r …

14.08.2026journal-article

Journal of Manufacturing and Materials Processing

Thermal Aging and Geometry-Driven Changes in Strength of 3D-Printed Polymers

Mohammad Reza Khosravani, Payam Soltani, Morteza Mohammadzaheri, Majid R. Ayatollahi

The benefits of additive manufacturing (AM, i.e., 3D printing) have made it one of the most widely used and favored production techniques across a variety of industries. In the current study, the influence of geometry and thermal aging on the mechanical strength of AMed parts has been investigated. In this context, specimens based on fused deposition modeling were printed using polylactic acid material. The specimens with three distinct geometries were created and analyzed since the geometry of AMed parts affects t …

14.08.2026journal-article

Revista Chilena de Rehabilitación y Actividad Física

Efectividad de la metodología de entrenamiento 1x2x3 sobre la fuerza, velocidad de la marcha y el equilibrio valorado sobre el test sppb en personas mayores de la comunidad

Boris Cariaga Araneda

ABSTRACT Objective: To evaluate the effectiveness of the 1x2x3 training methodology on muscle strength, walking speed, and functional balance in community-dwelling older adults, using the Short Physical Performance Battery (SPPB). Methodology: A longitudinal quasi-experimental study involving 31 participants (aged ≥65 years), divided into an experimental group (n=16) and a control group (n=15). The experimental group underwent an 8-week 1x2x3 training program, while the control group received a brief educational se …

14.08.2026journal-article

Frontiers in Public Health

Vulnerability of older adults to heatwaves: the Barcelona case

Blanca Arellano, Josep Roca, Carina Serra, Dolors Martínez

Heatwaves are becoming more frequent, intense, and persistent as a result of global warming, posing a growing public health challenge in Mediterranean cities. In Barcelona, this process is characterized by a pronounced increase in nighttime temperatures, amplified by the urban heat island effect and by a rapidly aging population, which together increase vulnerability to heat-related health impacts. This study aims to assess the effects of high temperatures on mortality in Barcelona, with a particular focus on older …

14.08.2026journal-article

Frontiers in Aging Neuroscience

Restoring anticipatory control through cognitive–motor dual-task training improves emotional and executive function in frail older adults

Luca Boccacci, Martina Scalia, Riccardo Borzuola, Valentina Camomilla, Domenico Campagna, Andrea Casella, Imma Ceriello, Natalie Ferrulli, Margherita Filosa, Chiara Fossati, Federica Galli, Andrea Macaluso, William Manzon, Camilla Panacci, Martina Parrella, Fabio Pigozzi, Sabrina Pitzalis, Franco Pio Siciliano, Arnaldo Zelli, Francesco Di Russo

Background Aging-related frailty is increasingly recognized as a multidimensional condition involving impairments in cognitive, emotional, and motor domains. Traditional interventions often fail to capture the complexity of real-world functioning, highlighting the need for more ecologically valid approaches. Objectives This study investigated the effects of a structured Cognitive–Motor Dual-Task Training (CMDT) protocol, incorporating alternating bilateral stimulation (BAS), on emotional regulation, executive funct …

14.08.2026journal-article

Geriatrics

Navigating Support for Informal Caregivers of Older Migrants with Dementia in The Netherlands: Insights from Patient Journey Mapping

Margaret von Faber, Suzan van der Pas

Background/Objectives: The aim of the study is to determine factors that affect informal caregivers’ ability to care for older migrants with dementia, with a broad aim of providing a framework for improving regional formal support. We used patient journey mapping as a method to identify experiences of informal caregivers. Methods: The study took place in three phases. In the first phase, the content of the patient journey was outlined, and semi-structured interviews were conducted with 14 informal caregivers of peo …

14.08.2026journal-article

Saúde Coletiva (Barueri)

Multimorbidity and Functional Disability in Older Brazilians: Contrasting Patterns in Basic and Instrumental Activities, 2013–2019

Nathalia Faquinelli, Dayanne Mykaelly de Sousa Marques, Natércia De Ávila Pessoa Silva, Letycia Manta Tomé, Kaio Henrique Correa Massa

Objective: To analyze the association between multimorbidity and functional disability in basic (BADL) and instrumental activities of daily living (IADL) among older Brazilian adults, and to assess changes between 2013 and 2019. Methods: A cross- sectional study was conducted using data from the 2013 and 2019 Brazilian National Health Survey, including individuals aged 60 years or older. Functional disability was assessed based on self-reported limitations in BADL and IADL, categorized dichotomously. Multimorbidity …

14.08.2026journal-article

Frontiers in Public Health

Geriatric syndromes and intrinsic capacity in older adults with coronary heart disease: a cross-sectional study in China

Jiaojiao Qiu, Shuaishuai Zhang, Yue Chen, Yan Wang, Yue Zhang, Nan Zhang, Qinzhi Cao, Guanchao Sun, Lin Zhou, Jin Sun, Man Li, Boyang Zeng, Zimei Chi, Shuxia Wang, Ping Zhu

Background Geriatric syndromes (GS) are highly prevalent among community-dwelling older adults with self-reported physician-diagnosed coronary heart disease (CHD), but their association with intrinsic capacity (IC) remains poorly characterized. Methods We analyzed cross-sectional data from 5,835 community-dwelling Chinese older adults with self-reported physician-diagnosed CHD (mean age 74.4 years; 65.8% women). GS burden (0 to ≥4) and specific comorbidities were examined against overall IC impairment and its five …

14.08.2026journal-article

Frontiers in Digital Health

An efficiency assessment of digital technology empowering healthy aging in China: an empirical study of the “internet plus nursing services” pilot program based on the DEA model

Lansong Huang, Anji Huang, Quansheng Wang

This paper is rooted in the Chinese context and focuses on “the empowerment of health and older adults' care through digital technology” as its core topic. It aims to systematically evaluate the quantitative impact of digital technologies such as wearable devices and telemedicine on the efficiency and cost control of health and care services for older adults in China. This study adopts an empirical research approach that focuses primarily on quantitative analysis, supplemented by evidence from contextual case studi …

14.08.2026journal-article

BMC Public Health

Retrospective narratives of COVID-19 experiences: a qualitative study of written accounts by people in public in the context of a performative intervention

Till Neugebauer, Amand Führer, Maren Schuster, Anne Marx, Franziska Waldschmitt, Yüce Yilmaz-Aslan, Patrick Brzoska

Abstract Background This qualitative study explored how people retrospectively described their experiences of the COVID-19 pandemic. It aimed how these experiences are remembered and interpreted over time. Methods A qualitative study design was employed, based on short texts written by members of the public during a performative intervention in public space. The texts were thematically analyzed to identify common experiences and emotions. Results The findings show that participants described the pandemic not only a …

14.08.2026journal-article

Gerodontology

Denture Stomatitis and Its Associations Among Older Adults in the United Arab Emirates

Nabeel H. Alsabeeha, Rahul S. Patil, Rubina T. Ali, Manal Awad, Momen A. Atieh

ABSTRACT Background Denture stomatitis is a common oral mucosal lesion among older adults wearing removable prostheses. Its prevalence and associated risk factors, however, vary across populations. Objective To describe denture stomatitis and its associations with patient‐ and prosthesis‐related factors among older adults wearing removable dentures in the United Arab Emirates. Methods 280 patients wearing 492 removable dentures were examined in a specialty dental facility in Ras Al‐Khaimah, United Arab Emirates. Cl …

14.08.2026journal-article

Frontiers in Aging Neuroscience

Exercise alone or combined with functional foods in aging and age-related diseases: targeting DNA damage, repair pathways, and genome integrity

Ying Ma, Xuejun Li, He Chen, Rongchang Fan

Aging is fundamentally associated with the gradual accumulation of DNA damage, which is instrumental in the initiation and advancement of age-associated pathologies, including neurodegenerative conditions such as Alzheimer’s disease and Parkinson’s disease. Recent studies indicate that lifestyle modifications—especially the consumption of functional foods and participation in consistent physical exercise—can influence cellular and molecular processes related to DNA repair, reduction of oxidative stress, and mainten …

14.08.2026journal-article

Frontiers in Medicine

Serum metabolic characteristics of interstitial lung disease: a potential link between endocrine aging and gut-derived metabolites

Lu Liu, Xinyi Wang, Jinling Xiao, Yandong Li, Shihuan Yu

Objective To analyze differences in serum metabolic profiles between patients with interstitial lung disease (ILD) and healthy controls in northern China using untargeted metabolomics techniques, to identify differentially expressed metabolites and key dysregulated pathways, and to identify potential metabolic biomarkers. Methods Thirty patients with interstitial lung disease (ILD) and 30 healthy controls were enrolled. Untargeted metabolomics analysis was performed using LC-MS/MS in both positive and negative ion …

14.08.2026journal-article

Frontiers in Psychiatry

Building an early warning model for the risk of suicide attempt in people with depression based on machine learning: a single-centre study

Mian Zhang, Wen Liu, Wenzhi Pei, Long Chen, Min Pan, Anzhen Wang, Boyu Zhang, Xialong Cheng, Wen Xie

Background Attempted suicide is one of the most serious clinical consequences for patients with depression, and early identification of high-risk individuals is crucial for preventing suicide deaths. Traditional clinical assessment often relies on subjective judgment, lacking objective biological markers and multi-dimensional data integration analysis. Objective This study aims to use machine learning algorithms to integrate demographic characteristics, clinical symptom scales, and blood biochemical indicators to c …