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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Belitung Nursing Journal

Negotiating faith in a hospital bed: A qualitative exploration of barriers to prayer (Solah) among hospitalised Muslim orthopaedic patients in Malaysia

Mohd Ariff Sharifudin, Yuzana Mohd Yusop, Mai Nurul Ashikin Taib, Mohd Fitri Omar, Al Hafiz Ibrahim, Anas Mohd Yunus

Background: For Muslim patients, performing the five daily prayers (Solah) is a non-negotiable pillar of faith and a vital source of spiritual solace during illness. In Malaysia, the Ibadah-Friendly Hospital (IFH) framework was established to support this need within holistic care. However, adherence remains low, particularly among patients with physical limitations, such as orthopaedic conditions, suggesting a significant gap between policy and lived experience. Objective: This study aimed to explore in-depth the …

28.08.2026journal-article

Communications Medicine

Venular-centered thrombo-inflammation drives microvascular failure after arterial recanalization in acute mesenteric ischemia

Déborah François, Lambert Kernanet, Melinda Bajul, Abigail Brami, Véronique Arocas, Marie-Christine Bouton, Dominique Cazals-Hatem, Kevin Guedj, Benoit Ho-Tin-Noé, Olivier Corcos, Yacine Boulaftali, Alexandre Nuzzo

Abstract Background Acute mesenteric ischemia (AMI) remains associated with high mortality despite prompt revascularization, suggesting that downstream ischemia–reperfusion injury contributes to poor outcomes. However, the microvascular mechanisms underlying this process are not entirely defined. Methods We analyzed admission blood samples from patients with arterial AMI and non-ischemic controls enrolled in the SURVIBIO diagnostic study (NCT03518099). We also investigated thrombo-inflammatory responses in a murine …

28.08.2026journal-article

Advances in Laboratory Medicine / Avances en Medicina de Laboratorio

Prediction of coagulation factor inhibitor levels using Random Forest model based on the activated partial thromboplastin time (aPTT) mixing study: model development and prototype application

Chulalak Kongkan, Pakaporn Detsuk, Sarawin Hnusing, Yanakamin Phomcharoen, Chadaporn Nokkong, Chaowanee Wangchauy, Saristha Buathong, Tipparat Penglong, Peempol Chokchaipermpoonphol

Abstract Objectives This study aimed to develop a machine learning approach to predict factor VIII inhibitor titers from activated partial thromboplastin time (aPTT) mixing study data. Methods Records of 173 patients who underwent factor VIII inhibitor testing at Songklanagarind Hospital from January 2023 to December 2025 were retrospectively analyzed. Predictor variables included mixing aPTT, age, and sex, with Bethesda assay inhibitor titer as the outcome. A two-stage hurdle Random Forest model was developed, con …

28.08.2026journal-article

Borneo Nursing Journal (BNJ)

Pengaruh Pemberian Edukasi Terhadap Kesiapan Orang Tua Dalam Mendeteksi Diabetes Melitus Pada Anak Di Wilayah Puskesmas Kuin Raya

Linda Lestariani, Cynthia Eka Fayuning Tjomiadi, Ahmad Syahlani, Rian Tasalim

Diabetes Melitus (DM) pada anak merupakan penyakit kronis yang terus meningkat prevalensinya.Peran orang tua sangat penting dalam mengenali tanda dan gejala awal, namun kesiapan orang tuadalam melakukan deteksi dini masih belum optimal, diperlukan upaya peningkatan pengetahuan dankesiapan melalui pemberian edukasi kesehatan. Penelitian ini bertujuan untuk mengetahui pengaruhpemberian edukasi terhadap kesiapan orang tua dalam mendeteksi diabetes melitus pada anak.Penelitian ini menggunakan pendekatan kuantitatif den …

28.08.2026journal-article

Journal of Public Budgeting, Accounting & Financial Management

Local self-government audit reporting in selected Balkan countries: a comparative content analysis of supreme audit institutions' reports

Ivan Dionisijev, Zorica Bozhinovska Lazarevska, Todor Tocev, Bojan Malchev

Purpose This study evaluates the transparency and reporting practices of local self-government (LSG) audit reporting across four Supreme Audit Institutions (SAIs), North Macedonia, Montenegro, Croatia and Slovenia, over the period 2015–2024. It examines how SAIs communicate municipal audit results, the extent to which reporting practices align with internationally recognized accountability principles and how differences in institutional contexts are associated with variation in reporting patterns. Design/methodolog …

28.08.2026journal-article

Scientific Reports

Enhancing clinical reasoning and diagnostic precision through scaling laws and multi-stage supervised fine-tuning in open-weight medical large language models

Lukasz Pawlik, Stanislaw Deniziak

Abstract The emergence of large language models offers unprecedented opportunities to transform clinical workflows. However, reliance on proprietary closed-source models poses significant risks to data privacy, institutional autonomy, and reasoning transparency. This study investigates the optimization of open-weight architectures, specifically the Llama-3.1-8B and Qwen2.5-14B-Instruct families, to function as specialized diagnostic tools rather than general-purpose conversational agents. Utilizing the MedQA USMLE- …

28.08.2026journal-article

Health Research Journal of Indonesia

Hubungan Pola Asuh Orang Tua dengan Perilaku Picky Eating pada Anak Usia Prasekolah di TK Islam Bakti Kauman Batang

Hesti Fathan Nurfais Fauziah, Fatikhah, Penthatasya, Yulia Ardiyanti

Latar Belakang: Picky eating merupakan salah satu masalah perilaku makan yang sering dijumpai pada anak usia prasekolah dan berkaitan dengan kecukupan asupan gizi serta pertumbuhan anak. Pola asuh orang tua merupakan aspek pengasuhan yang sering dikaji dalam hubungannya dengan perilaku makan anak, namun hasil penelitian sebelumnya masih menunjukkan temuan yang belum konsisten. Tujuan: Menganalisis hubungan pola asuh orang tua dengan perilaku picky eating pada anak usia prasekolah di TK Islam Bakti Kauman Batang. Me …

28.08.2026journal-article

EPMA Journal

Evidence-based recommendations for advancing the chronic pelvic pain syndrome management by the paradigm change from reactive symptom suppression to proactive 3PM-guided patient-centered care

Ousman Bajinka, Lamarana Jallow, Na Li, Christian Kuhn, Walther Kuhn, Ivana Stetkarova, Olga Golubnitschaja, Xianquan Zhan

Abstract Chronic pelvic pain syndrome (CPPS) encompasses a heterogeneous group of debilitating conditions including interstitial cystitis/bladder pain syndrome (IC/BPS), chronic abacterial prostatitis, endometriosis, and pelvic congestion syndrome, among others. Despite advances in symptomatic management, CPPS remains challenging due to its multifactorial etiology, complex phenotypes, and poor response to conventional reactive treatments. On the other hand, sympathetic overdrive phenotype (SOP) carriers frequently …

28.08.2026journal-article

Frontiers in Medicine

Precise diagnosis and management of non-traumatic radial nerve palsy attributed to multiple rare etiologies: case study and literature review

Yanchen Dong, Nanfei Zheng, Hongyue Men, Chen Xie

While non-traumatic radial nerve palsy is relatively rare, cases triggered by a single etiological factor pose minimal diagnostic and therapeutic challenges. However, for radial nerve palsy driven by multiple factors, the overlapping or masking effects of symptoms and signs from distinct etiologies complicate accurate diagnosis and optimal management. This complexity is further amplified when all contributing factors are rare, presenting a more formidable challenge to precise diagnosis and treatment selection. We p …

28.08.2026journal-article

Journal of Complementary and Integrative Medicine

Evaluation of anti-osteoarthritic activity of hydroalcoholic extract of Moringa oleifera by using papain-inducing model in experimental animals

Vaibhav Sangameshwar Gavane, Snehal Ambadas Gojare, Deepti Dinesh Bandawane

Abstract Background The anti-inflammatory, anti-arthritic, and antioxidant qualities of Moringa oleifera have long been used to treat inflammation and various types of arthritis. Objectives To evaluate the hydroalcoholic extract of Moringa oleifera pods in a papain-induced animal model. Materials and methods Hydroalcoholic extraction was used to obtain the hydroalcoholic extract of Moringa oleifera (HEMO), and its phytochemical constituents were examined. In Wistar rats, osteoarthritis was induced by intra-articula …

28.08.2026journal-article

Belitung Nursing Journal

Family-centered early intervention: A concept analysis to guide pediatric and community nursing practice

Mardiyanti Mardiyanti, Yeni Rustina, Nani Nurhaeni, Nur Agustini

Background: Family-Centered Early Intervention (FCEI) is increasingly recognized as a framework for promoting child development and family empowerment. However, its application in nursing practice may be limited by the lack of a clear distinction between FCEI, Family-Centered Care (FCC), and Patient- and Family-Centered Care (PFCC). Objective: To clarify the concept of FCEI and distinguish it from FCC and PFCC by identifying its defining attributes, antecedents, consequences, and empirical referents. Methods: Walke …

28.08.2026journal-article

BMC Sports Science, Medicine and Rehabilitation

Optimizing exercise for breast cancer survivors: a randomized controlled trial of daily individualization of high-intensity online concurrent training guided by autonomic modulation

Ana Myriam Lavín-Pérez, Daniel Collado-Mateo, Inés Nieto, Xián Mayo, Carmen Hinojo González, Ana de Juan Ferré, Gary Liguori, Alfonso Jiménez

Abstract Background Breast cancer and its treatments cause physical and physiological side effects that exercise can mitigate. However, there is little evidence on the effects and feasibility of high-intensity remote supervised training. In addition, there is no evidence of the effect of individualizing intensity prescription based on autonomic control in this population. Thus, this study aimed to compare the effects of two concurrent online exercise programs, pre-planned intensity prescription (PPI) and intensity …

28.08.2026journal-article

Esophagus

Treatment-dependent and independent prognostic value of inflammation-based nutritional indices in immune checkpoint inhibitor-based therapy for esophageal cancer

Hiroki Matsuda, Tomoki Makino, Shuichiro Hara, Shigeto Nakai, Takaomi Hagi, Kota Momose, Kotaro Yamashita, Takuro Saito, Koji Tanaka, Atsushi Takeno, Tsuyoshi Takahashi, Masaaki Motoori, Yukinori Kurokawa, Hidetoshi Eguchi, Yuichiro Doki

Abstract Background Phase III trials have established the efficacy of immune-based therapies for unresectable advanced or recurrent esophageal squamous cell carcinoma (ESCC). However, real-world evidence comparing regimens and clinically applicable prognostic biomarkers remains limited. Methods We retrospectively evaluated 245 patients with unresectable advanced/recurrent ESCC treated with first-line 5-fluorouracil plus cisplatin combined with nivolumab or pembrolizumab (CF + ICI; n = 114), first-line ipilimumab pl …

28.08.2026journal-article

Frontiers in Medicine

Efficacy and safety of ceftazidime-avibactam versus tigecycline in the treatment of pneumonia caused by carbapenem-resistant Klebsiella pneumoniae

Tongfei Yang, Mao Xu, Lu Cao, Yaling Shi, Xianpeng Shi

Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) causes severe high-mortality nosocomial pneumonia. Ceftazidime-avibactam (CAZ-AVI) and tigecycline (TGC) are key CRKP antimicrobials, but direct comparative efficacy and safety data are limited. This retrospective study compared clinical efficacy and safety of CAZ-AVI-based versus TGC-based regimens for CRKP pneumonia, and explored factors associated with all-cause mortality to inform clinical practice. Methods A total of 63 patients with CRKP pulmonary i …

28.08.2026journal-article

Gastroenterologie a hepatologie

Klinická a experimentální gastroenterologie 4/2026

Tomáš Hucl

Vážené a milé kolegyně a kolegové, dovolte mi pozvat vás k přečtení dalšího čísla Gastroenterologie a hepatologie a představit vám část jeho obsahu věnovanou klinické a experimentální gastroenterologii. Irena Fillová z Martina se v přehledovém článku věnuje problematice dysfagie a především úloze klinického logopeda v její diagnostice a léčbě. Dysfagie není pouze problémem ezofageálního transportu, ale často zahrnuje také orofaryngeální a funkční poruchy. Autorka proto zdůrazňuje význam interdisciplinární spoluprác …

28.08.2026journal-article

New Zealand Medical Journal

The public in Aotearoa New Zealand support policies to reduce alcohol harm: results from a national survey

Rose Crossin, Ella Iosua, Emma Shields, Andrew Gray, Louise Signal, Rana Peniamina, Bronwen McNoe

aim: Alcohol consumption is a cause of at least seven types of cancer and contributes substantially to Aotearoa New Zealand’s cancer burden; population-level interventions are one way to reduce this burden. This study therefore investigates: 1) public support for increased action by politicians to reduce alcohol-related harm, and 2) what policies are both strongly supported by the public and have high consistency of support by voting intention. methods: Data are from a nationally representative, cross-sectional onl …

28.08.2026journal-article

Health Research Journal of Indonesia

Pengaruh Edukasi PHBS Menggunakan Media Flash Card Terhadap Tingkat Pengetahuan Dan Sikap Dalam Pencegahan Diare

Elsa Meylinda, Dadang Kusbiantoro, Sylvi Harmiardillah

Pendahuluan Diare merupakan salah satu masalah kesehatan yang sering terjadi pada anak dan berisiko menyebabkan dehidrasi. Rendahnya pengetahuan dan sikap mengenai Perilaku Hidup Bersih dan Sehat (PHBS) menjadi salah satu faktor yang meningkatkan risiko diare. Penelitian ini bertujuan menganalisis pengaruh edukasi PHBS menggunakan media flash card terhadap tingkat pengetahuan dan sikap dalam pencegahan diare pada siswa SDN 1 Jubel Kidul. Metode Penelitian ini menggunakan desain pre-experimental dengan pendekatan on …

28.08.2026journal-article

Journal of Health Science and Reports

Training in Cardiopulmonary Resuscitation and in-Hospital Cardiopulmonary Arrest Treated in A Second-Level Hospital in Spain

Ion Koldobika Iribar Diéguez, Jon Gil Barreiro, Irati Lanceta Barandiarán, Daniel Uzal Escudero, Aitziber Tranche Aristizabal, Ibai Mauduit Aznar, Irati Arístegi Sánchez, Itziar González Etxepare, María Gómez Martínez, Igor Garín Martín

Introduction: Cardiopulmonary arrest is a leading cause of premature death; it is unpredictable and potentially reversible. When it occurs in a hospital, the patient has a greater chance of survival. Bidasoa Hospital has a cardiopulmonary resuscitation training group and a structured response system for in-hospital cardiac arrest.Objective: To evaluate the training program and the epidemiological characteristics of in-hospital cardiorespiratory arrests treated since 2016.Method: Observational, retrospective and des …

28.08.2026journal-article

Belitung Nursing Journal

Preventing iron deficiency anemia in rural Indonesia: Experiences and support needs of pregnant women and healthcare providers — a qualitative descriptive study

Erli Zainal, Sri Sulistyowati, Agung Wibowo, Widiyanto Widiyanto

Background: Iron deficiency anemia remains a significant public health concern among pregnant women, particularly in rural areas of low- and middle-income countries. Despite routine antenatal care services and iron–folic acid supplementation programs, adherence to supplementation and effective anemia prevention remain challenging. Understanding how pregnant women and healthcare providers experience and respond to these challenges is essential for strengthening anemia prevention efforts in rural maternal health serv …

28.08.2026journal-article

Frontiers in Medicine

Development and evaluation of a case-based learning program integrated with the BOPPPS model in neurosurgical residency training: a prospective controlled educational study

Jun Shen, Zhengyang Zhang, Qi Zhang, Zihao Zhou, Ziji Li, Shaolin Zhang, Qian An, Pengcheng Xu

Background Neurosurgical residency training requires teaching strategies that promote clinical reasoning and competency development beyond traditional lecture-based instruction. Although case-based learning (CBL) and the BOPPPS instructional model have each shown educational benefits, evidence regarding their integrated application in neurosurgical residency training remains limited. This study aimed to develop and evaluate a structured CBL program integrated with the BOPPPS instructional model and to assess its ed …

28.08.2026journal-article

Gastroenterologie a hepatologie

Severe upadacitinib-induced anemia in a multi-refractory Crohn’s disease patient – a case report

Anna Gojdicova, Igor Sturdik, Juraj Toth, Stanislav Majna, Jana Skubakova, Michaela Granak-Pytliakova, Tibor Hlavaty

Úvod: Inhibítory Janusovej kinázy (JAK) predstavujú účinnú perorálnu liečebnú možnosť pri stredne ťažkej až ťažkej forme zápalového ochorenia čriev (IBD), ktoré nereaguje na konvenčné a biologické lieky. Boli hlásené hematologické nežiaduce účinky, avšak závažná myelosupresia je zriedkavá a jej klinické zvládnutie – najmä rozhodnutie o pokračovaní liečby u pacientov, ktorí z nej majú podstatný prínos – naďalej predstavuje výzvu. Popis prípadu: Predkladáme prípad 45-ročnej ženy s Crohnovou chorobou postihujúcou hrub …

28.08.2026journal-article

Belitung Nursing Journal

Strengthening evidence-based practice culture in nursing: An ethnographic study in the central highlands of Vietnam

Dang Vuong Nguyen, Apinya Jumpamool

Background: Evidence-based practice (EBP) is a vital approach to achieve Quality Improvement (QI) in healthcare services by ensuring that nursing care is grounded in the best available evidence. However, the integration of EBP into nursing in Vietnam is often lacking, presenting a significant challenge for both healthcare leaders and individual practitioners. Objectives: This qualitative study aimed to understand the workplace culture regarding EBP implementation among Vietnamese nurses, exploring the shared belief …

28.08.2026journal-article

World Journal of Gastroenterology

Clinical efficacy and safety of laparoscopic hybrid surgery for simultaneous resection of colorectal cancer liver metastases

Tian-Shuai Zhang, Xiao-Ming Zhu, Rong-Bo Wen, Le-Qi Zhou, Hai-Feng Gong, En-Da Yu, Hao Wang, Gang Li, Wei-Ping Zhou, Li-Qiang Hao, Guan-Yu Yu, Wei Zhang

BACKGROUND Simultaneous resection of colorectal cancer liver metastases (CRLM) has been widely adopted; however, clinical efficacy still varies across different surgical approaches, and the best surgical strategy remains controversial. AIM To investigate the efficacy and safety of laparoscopic hybrid surgery (LHS) vs total open surgery (TOS) the in simultaneous resection of CRLM. METHODS This was an observational study conducted at a tertiary medical center, enrolling 266 patients who undergoing simultaneous resect …

28.08.2026journal-article

New Zealand Medical Journal

Overwhelming and cross-party public support for robust tobacco control measures to achieve a Smokefree Aotearoa New Zealand: findings from a national survey

Richard Edwards, Ella Iosua, Amanda Dodd, Andrew Gray, Rana Peniamina, Louise Signal, Bronwen McNoe

aim: Tobacco is a leading cause of preventable disease, mortality and health inequity in Aotearoa New Zealand where smoking prevalence decline has stalled. Further reductions will likely require tobacco control measures beyond business-as-usual approaches. We report survey support for tobacco control and vaping regulation policies. methods: We recruited adults from an online panel using quota sampling. We assessed support using a structured questionnaire for: reducing nicotine content in smoked tobacco products; re …