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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

Frontiers in Cardiovascular Medicine

Artificial intelligence-empowered echocardiography: an updated review of clinical management in hypertrophic cardiomyopathy

Miao Zhang, Shanshan Yuan, Hongyan Dai, Guoan Wang

Hypertrophic cardiomyopathy (HCM) is a common and highly heterogeneous inherited cardiomyopathy characterized by complex clinical phenotypes and diverse disease trajectories, posing significant challenges for early diagnosis, precise phenotypic classification, and risk stratification. Owing to its noninvasive nature, repeatability, and wide availability, echocardiography remains the cornerstone imaging modality for the diagnosis and longitudinal management of HCM. However, conventional echocardiographic analysis re …

27.08.2026journal-article

International Journal of Molecular Sciences

Effect of Dupilumab on Allergen-Specific IgE Levels and Clinical Tolerance in Patients with Food Allergy: A Systematic Review

Magdalena Grześk-Kaczyńska, Szymon Kaczyński, Bernadetta Kosztulska, Magdalena Rydzyńska, Tomasz Rosada, Natalia Ukleja-Sokołowska

Food allergy is a growing global health concern associated with significant dietary restrictions, impaired quality of life, and risk of severe allergic reactions. Dupilumab, a monoclonal antibody targeting the interleukin-4 receptor alpha (IL-4Rα), inhibits IL-4 and IL-13 signaling and has demonstrated efficacy across multiple type 2 inflammatory diseases. This systematic review aimed to evaluate the effects of dupilumab on food allergy outcomes in pediatric and adult patients. Across studies, dupilumab treatment w …

27.08.2026journal-article

Clinical Psychology & Psychotherapy

Are Metacognitive Beliefs and Cognitive Flexibility Associated With Cannabis Use Disorder In Adolescents? A Case–Control Study

Neval Kızıl, Masum Öztürk, Fatma Subaşı Turgut, Yağmur Soysal, Ayfer Gözü Pirinççioğlu

ABSTRACT Objective Cannabis is among the most commonly used substances by adolescents and is frequently associated with the development of addiction. Various individual, environmental and psychological factors are associated with the onset and maintenance of cannabis use disorder (CUD). Our study aimed to compare levels of depression, anxiety, stress, perceived cognitive flexibility and metacognitive beliefs in adolescents diagnosed with CUD with those in a healthy control (HC) group. Another objective was to inves …

27.08.2026journal-article

Frontiers in Psychology

Artificial intelligence-assisted speaking in Spanish as a foreign language: effects on foreign language emotions and willingness to communicate

Yifan Miao, Pingping Hu

Introduction Although AI-powered conversational tools are increasingly used in foreign language education, little is known about their longitudinal effects on learners’ emotional experiences and willingness to communicate (WTC), particularly among beginner learners of languages other than English. Grounded in Positive Psychology, Control-Value Theory, and the WTC framework, this study examined the effects of AI-assisted speaking practice using TalkPal AI on foreign language enjoyment (FLE), foreign language anxiety …

27.08.2026journal-article

F1000Research

How to measure the perimeter from digital images

David Legland

Image analysis aims at extracting quantitative information from digital images. As for any measurement method, the measures obtained from image analysis present some measurement errors that should be better considered during interpretation of results. This work investigates the quality of measures obtained from image analysis based on measurements on synthetic shapes with various geometries, sizes, positions and orientations, by focusing on the methods available in common image analysis software. The perimeter is u …

27.08.2026journal-article

JURPIKAT

Akselerasi Validasi Spasial melalui Plotting Data Digital PTSL di Loket Yuridis Kantor Pertanahan

Toton Fanshurna, Nadia Ludyanti Esya Putri, Calista Putri Fitriana, Rensi Haiziah

Pendaftaran Tanah Sistematis Lengkap (PTSL) tak sekadar menghasilkan dokumen, melainkan membentuk basis data pertanahan yang menuntut ketepatan serta keterhubungan informasi yuridis dan spasial. Masalah timbul saat data digital dalam jumlah besar memerlukan penataan ulang akibat ketidaksesuaian informasi.Kegiatan pengabdian ini bertujuan mendukung percepatan validasi spasial melalui plotting data digital PTSL di Loket Yuridis Kantor Pertanahan Kabupaten Jember. Metode dilakukan secara partisipatif, meliputi identif …

27.08.2026journal-article

Journal of Plastic Surgery and Hand Surgery

Clinical outcomes of a defect-adapted strategy for free fibular great toe flaps in finger reconstruction: a retrospective series of 35 cases

Yangyang Liu, Huajian Zhou, Haoran Jiang, Jun Zhu, Renjie Li, Mingyu Jia

Background: To evaluate the clinical outcomes of a personalized surgical strategy for small-to-medium finger defects, utilizing either free dorsal toe or plantar proper digital artery flaps. Methods: We retrospectively analyzed 35 patients with finger defects (March 2021–January 2025). Patients were assigned by defect characteristics to Group A (pulp defects, n = 21; plantar proper digital artery flap) or Group B (dorsal/lateral defects, n = 14; modified dorsal toe artery flap preserving the plantar proper neurovas …

27.08.2026journal-article

JAMA Health Forum

Mental Health and Construction—Intervening to Prevent Collapse

Rosa M. Gonzalez-Guarda, Molly Hayes, Luke Smith

This JAMA Forum discusses mental health and substance abuse problems among US construction workers and proposes a national strategy to ensure that evidence-based prevention, early identification, and treatment reach this population.

27.08.2026journal-article

Ege Eğitim Dergisi

In-Service English Teachers' Attitudes toward Artificial Intelligence in Education

Pelin Derinalp

The rapid advancement of technology requires teachers to adapt to this change. Artificial intelligence (AI) is increasingly being used in education and is gaining influence. Therefore, examining teachers' attitudes toward AI is important for the effective integration of technology. This study investigates the attitudes of English teachers in Türkiye toward AI. Using qualitative descriptive research design, participants were first asked to provide written definitions of AI. Subsequently, four focus group discussions …

27.08.2026journal-article

Journal of the National Comprehensive Cancer Network

Fostering Improvements in Equitable Care Delivery: Insights From the Health Equity Report Card (HERC) Pilot in Academic Cancer Centers

Ashley Orr, Taneal D. Carter, Mallory Stubblebine, Heather McKee Hurwitz, Tiffany Go, Leticia Mercado, Darryl Outlaw, Elizabeth Bouchard, Levent Dumenci, Crystal S. Denlinger, Alyssa A. Schatz

Background: The Health Equity Report Card (HERC) was developed to support institutions in measuring equitable care practices and implementing improvement efforts. An objective of this study was to determine whether academic cancer centers can use their baseline HERC scores to identify institution-specific strategies to improve equitable care delivery. Methods: This quality improvement study collected quantitative and qualitative data from 5 NCCN Member Institutions about their quality improvement efforts in respons …

27.08.2026journal-article

Clinical Cancer Research

Focused Ultrasound-Enhanced Drug Delivery to Brain Tumors: Quantitative and Translational Insights from CNS Physiologically Based Pharmacokinetic Modeling

Andrew Wu, Charuka Wickramasinghe, Yuanyuan Jiang, Xun Bao, Jing Li

Abstract Purpose: Successful clinical translation of focused ultrasound (FUS)-induced blood-brain barrier (BBB) opening strategy to brain cancer therapy has been hindered by limited quantitative understanding of CNS pharmacokinetics. Using a physiologically based pharmacokinetic (PBPK) modeling framework, this study aimed to quantitatively characterize FUS-modulated CNS pharmacokinetics and identify key determinants of potential clinical benefits. Experimental Design: A previously validated 9-compartment CNS PBPK m …

27.08.2026journal-article

Clinical Case Reports

Severe Multiorgan Failure Triggered by Infection in an Adult With Decades of Untreated Sickle Cell Disease: A Case Report

Sara Shahidi, Gisha Mohan

ABSTRACT A 67‐year‐old man with decades of untreated sickle cell disease developed septic shock with multiorgan failure, splenic infarction, and marrow fibrosis; his genotype could not be confirmed. He recovered with intensive supportive care, with hydroxyurea initiated for long‐term disease modification, illustrating catastrophic infection‐triggered decompensation despite prolonged clinical quiescence.

27.08.2026journal-article

International Journal of Research in Economics and Finance

Strategic Management of Higher Education Reforms in the Digital Era: Driving Human Capital Value through Ethical Digital Leadership

Yassamine El Jai, Latifa Belfakir

The rapid evolution of the global digital economy requires a profound structural transformation within Higher Education Institutions (HEIs) in order to develop resilient and highly competitive Human Capital (HC). This paper examines the intersection of Digital Transformation (DT), institutional leadership, and HC optimization within modern educational reforms. Digital tools such as Artificial Intelligence (AI) or Virtual Learning Environments (VLEs) usually offer unprecedented opportunities to scale up HC value glo …

27.08.2026journal-article

Cadernos Cajuína

Inteligência Artificial na educação superior: impactos pedagógicos e reconfigurações epistemológicas

Alfredo Bravo Marques Pinheiro, Maria Deuceny da Silva Lopes Bravo Pinheiro

A inteligência artificial (IA) vem transformando práticas de ensino, aprendizagem e produção acadêmica na educação superior, ao mesmo tempo em que suscita questões sobre os sentidos e as responsabilidades da formação universitária. Este artigo analisa as possibilidades e os desafios relacionados à incorporação da IA na educação superior, considerando aspectos pedagógicos, éticos e epistemológicos. A pesquisa, de natureza qualitativa, foi desenvolvida por meio de levantamento bibliográfico e documental, envolvendo l …

27.08.2026journal-article

Journal of Medical and Dental Investigations

Can digital impression methods eliminate the current problems of conventional impression techniques?

Yakup Kantaci

Conventional impression materials remain a cornerstone of routine dental practice, yet they carry well-documented drawbacks, including a pronounced gag reflex, limited patient comfort, potential soft-tissue trauma, dimensional changes with temperature and elapsed time, the need for disinfection, cross-infection risk, and susceptibility to distortion during transport, storage, and laboratory handling. Digital impression systems have been introduced to overcome these limitations, and their use in dentistry—particular …

27.08.2026journal-article

Karya Journal of Health Science

THE EFFECT OF EDUCATION GIVEN TO HEMODIALYSIS PATIENTS ON SELF-CARE AGENCY AND FLUID CONTROL: A RANDOMIZED CONTROLLED TRIAL

Zeynep Yılmaz, Mağfiret Kara Kaşıkçı, Fatmanur İrgin

Objective: This study investigated the effects of education on hemodialysis management provided to patients receiving hemodialysis treatment on self-care agency and fluid control.Method: The study was conducted using a randomized controlled experimental design. Participants receiving hemodialysis treatment were divided into two groups: the intervention group (n=26) and the control group (n=28). Data were collected using the Descriptive Information Form, Self-Care Agency Scale, and Fluid Control in Hemodialysis Pati …

27.08.2026journal-article

Journal of Global Social Transformation

Generative Artificial Intelligence and Linguistic Identity in Multilingual Academic Writing among Pakistani Postgraduate Learners

Muhammad Aslam Khan, Dr. Muhammad Akram

Generative artificial intelligence (GenAI) is transforming academic writing; however, its implications for the linguistic identity and authorial ownership of multilingual writers remain insufficiently understood, particularly in South Asian higher education. This cross-sectional correlational study examined the relationships among GenAI dependence, perceived linguistic identity erosion, and translingual agency among 92 university-level students. Data were collected using the newly developed 27-item Generative AI an …

27.08.2026journal-article

Materials

Antibacterial Interventions for Orthodontic Appliances; Surface Modifications, Coatings and Bulk-Incorporated Antibacterial Agents: Materials, Mechanisms and Clinical Application—A Scoping Review

Berta Furió-Alonso, Javier Gil, Danica Nikolic Jovanovic, Andreu Puigdollers-Pérez

Biofilm accumulation on orthodontic appliances is a recognized risk factor for white spot lesion formation and caries during treatment. Antibacterial surface modifications and coating strategies have been proposed as appliance-level preventive approaches. Studied interventions in the literature span true thin-film surface coatings, plasma-based and ion-implantation surface modifications, and bulk-incorporated antibacterial agents in appliance matrix materials. Yet the extent to which in vitro efficacy translates to …

27.08.2026journal-article

Biosensors

Artificial Intelligence in Electrochemical Sensing: A Network Evidence Map of Translational Barriers and Pathways to Point-of-Care Deployment

Muhammad Saqib, Elena I. Korotkova, Kunquan Li, Neda Firoz, Mrinal Vashisth, Amrit L. Hui, Olga I. Lipskikh, Pradip Kumar Kar

The integration of artificial intelligence (AI) and machine learning (ML) with electrochemical sensing has revolutionized analytical diagnostics by overcoming traditional limitations such as signal drift, peak overlapping, and matrix interference. However, despite the exponential growth of this field, a unified framework evaluating translational feasibility remains absent. This review critically analyzes AI/ML architectures applied to electrochemical sensors and biosensors from 2016 to 2025. To the best of our know …

27.08.2026journal-article

BMC Oral Health

Oral findings and antiresorptive therapy exposure duration in postmenopausal women with osteoporosis: a cross-sectional cohort study

Safiyye Süslü, Håvard J Haugen, Tormod Bjartveit Krüger, Bente B. Herlofson, Janne Elin Reseland, Erik Fink Eriksen

Abstract Background Oral findings are common among older adults, but it is unclear whether they vary with the duration of antiresorptive therapy (ART) exposure or relate to the severity of osteoporosis in postmenopausal women. Methods In this cross-sectional cohort ( n = 129), postmenopausal women undergoing osteoporosis assessment/follow-up were stratified by ART exposure duration: no current ART control (G1, n = 50), short ART (G2, 3–5 years; n = 39), and long ART (G3, > 5 years; n = 40). The prespecified primary …

27.08.2026journal-article

Revista Electrónica Educare

Alfabetización en inteligencia artificial en la formación inicial docente: Desarrollando competencias iniciales

Brahiam Ramírez, Soledad Estrella, María Inés Pezoa, Raimundo Olfos, Marcela Parraguez

Objective. To explore how preservice mathematics teachers demonstrate competencies in artificial intelligence based on an AI reference framework. Methodology. The study employed a qualitative exploratory-descriptive design. The sample consisted of 11 preservice mathematics teachers. Data were collected through self-learning modules implemented during the professional practicum, with rubrics used as assessment instruments. Participants’ responses, products, application proposals, and reflections on professional lear …

27.08.2026journal-article

Brazilian Journal of Implantology and Health Sciences

Efeitos cardiovasculares e mecanismos moleculares da terapia combinada com inibidores de SGLT2 e agonistas do receptor de GLP-1: uma revisão sistemática pré-clínica

Roberto Guilherme Rosa Morais, Andreus Cristhian Linhares Andrade

Introdução: Inibidores do cotransportador de sódio-glicose 2 (iSGLT2) e agonistas do receptor do peptídeo semelhante ao glucagon tipo 1 (GLP-1RA) apresentam efeitos metabólicos, cardiovasculares e renais potencialmente complementares. Contudo, os mecanismos moleculares associados à combinação dessas classes ainda não estão completamente sistematizados. Objetivo: Sintetizar evidências pré-clínicas sobre os mecanismos moleculares e fisiopatológicos da combinação entre iSGLT2 e GLP-1RA, com ênfase nos efeitos cardiova …

27.08.2026journal-article

Engineering, Construction and Architectural Management

Information technology integration capability, digital marketing capability and construction enterprise performance: a moderated mediation analysis

Xiaolin Li, Ziyu Wang, Ruirui Zhang, Linpu Guo, Qiaoyan Yuan, Songbo Zhu

Purpose This study intends to explore whether information technology integration capability (ITIC), digital marketing capability and cross-channel integration capability (CIC) can improve construction enterprise performance (CEP) in China's construction industry amid global informatization, as well as the moderating role of digital platform capability between ITIC/digital marketing capability and CIC. Design/methodology/approach A theoretical model based on the research hypotheses proposed in this study was develop …

27.08.2026journal-article

Frontiers in Oral Health

Comparative effectiveness of therapeutic ultrasound and pharmacotherapy in the management of muscular temporomandibular disorders: a randomized clinical trial

M. Subhikshaa, Prathima Shetty, K. M. Veena, Prashanth Shenoy, Rachana Prabhu, Laxmikanth Chatra

Introduction Temporomandibular disorders (TMDs) of muscular origin are a common cause of chronic orofacial pain and functional limitation. Conservative management includes pharmacotherapy and physiotherapeutic modalities such as therapeutic ultrasound. However, evidence directly comparing their effectiveness remains limited. This randomized clinical trial compared therapeutic ultrasound and pharmacotherapy in reducing pain intensity and improving mandibular function in patients with muscular TMDs. Materials and met …