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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
29.08.2026journal-article

BMC Complementary Medicine and Therapies

Chinese herbal medicine (Yiqi Huayu Jiedu Decoction) combined with chemotherapy for preventing postoperative recurrence and metastasis in elderly gastric cancer patients: protocol for a multicenter, double-blind, randomized, placebo-controlled trial

Peipei Yang, Jian Wang, Xiaoyu Wu, Ju Yang, Yan Sun, Xiaowei Wei, Jun Wu, Zhengxiang Han, Yanzhi Bi, Zhenguo Zhao, Ran Yang, Mengzhu Yang, Peng Shu

Abstract Introduction Gastric cancer (GC) has a generally unfavorable prognosis. Elderly patients often tolerate dual-drug chemotherapy poorly, experience limited benefits from monotherapy, and face high rates of postoperative recurrence and metastasis. To address this unmet clinical need, this study evaluates the efficacy and safety of Yiqi Huayu Jiedu Decoction (YHJD) combined with chemotherapy in preventing recurrence and metastasis in elderly patients with stage II/III GC after surgery. Method This is a multice …

29.08.2026journal-article

Public Health Journal

Hubungan Pengetahuan dan Masakerja Tenaga Kesehatan dalam Pengelolaan Limbah Medis di Rumah Sakit Umum Mufid Tahun 2026

Maifrizal Maifrizal, Muhammad Shalahuddin, Dara Maulida, Wahidanur Wahidanur

Limbah medis rumah sakit berpotensi menularkan penyakit sehingga memerlukan pengelolaan yang sesuai standar. Survei awal di Rumah Sakit Umum Mufid Sigli menunjukkan peningkatan volume limbah infeksius lebih dari 31% dalam tiga bulan terakhir, disertai temuan kesenjangan antara pengelolaan oleh petugas. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan dan masa kerja tenaga kesehatan dalam pengelolaan limbah medis di rumah sakit umum Mufid tahun 2026. Penelitian bersifat survei analitik dengan pendekata …

29.08.2026journal-article

European Journal of Nutrition

Effects of reduced gluten intake through the inclusion of yellow pea-based products on abdominal symptoms in habitual wheat consumers: a non-randomized clinical trial

Hitoshi Shimbo, Mamoru Ito, Yuto Aoki, Joto Yoshimoto, Mikiya Kishi, Jiro Saito, Yukihiro Ohya, Masashi Nakamura, Senju Hashimoto, Akiko Yagami

Abstract Purpose Increasing attention has been paid to individuals who report gastrointestinal symptoms following wheat consumption. In addition to wheat allergy and celiac disease, non-celiac gluten sensitivity (NCGS) has been proposed as a clinical entity. Despite persistent symptoms, many affected individuals continue to consume wheat-containing foods. We aimed to investigate the impact of replacing wheat-based foods with gluten-reduced foods, specifically yellow pea pasta (YPP), bread (YPB), and chips (YPC), on …

29.08.2026journal-article

Journal of Medicine and Health Research

A Descriptive Study to Assess the Prevalence of Factor Related to CKD among Patients with CKD Admitted at NMCH Jamuhar, Rohtas, Bihar, India

K. Latha, Dinesh Kumawat, Anish Kumar, Chandan Kumar Purbey, Rohit Kumar, Beauty Kumari, Kajal Kumari

Background: Chronic Kidney Disease (CKD) is a progressive and irreversible disorder that has emerged as a major global public health challenge because of its increasing prevalence, high morbidity and mortality, and economic burden. Diabetes mellitus, hypertension, obesity, smoking, cardiovascular disease, and prolonged use of nephrotoxic drugs are recognised as major contributors to CKD progression. Early identification of these factors is essential for reducing complications and improving patient outcomes. Objecti …

29.08.2026journal-article

PKLI Journal of Health Sciences

Absence of Epidemiological Evidence on Anorexia Nervosa Among Adolescents in Pakistan

Muhammad Soban, Bisma Tariq

Anorexia nervosa is a severe psychiatric disorder associated with significant morbidity and elevated mortality risk. Despite its clinical importance, there is a striking lack of epidemiological evidence regarding its burden among adolescents in Pakistan. This letter highlights a critical literature gap identified during the conduct of a systematic review and meta-analysis that aimed to determine the prevalence and risk factors of anorexia nervosa in Pakistani adolescents. An extensive search of multiple electronic …

29.08.2026journal-article

Translational Medicine

Early discontinuation of dual antiplatelet therapy after PCI in patients at high bleeding risk: an OCT-guided clinical case

A. A. Prokhorikhin, Yu. V. Kukushkina, D. D. Zubarev, A. V. Gorbatykh, K. A. Rzaeva

Background. Optimizing the duration of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) remains challenging, especially in patients with high bleeding risk and diabetes mellitus, where stent thrombosis risk is significantly increased due to delayed endothelialization. Objective. To demonstrate the safety of early DAPT discontinuation based on individual assessment of stent endothelialization using optical coherence tomography (OCT). Materials and Methods. We present a clinical case of …

29.08.2026journal-article

International Journal of Research in Medical Sciences

A cross-sectional study of etiology, clinical profile, prognosis and outcome of acute kidney injury in a tertiary care hospital

Yafas Nazir Khan, Mansi, Rolanda Saint Louis, Shehla Ashraf, Purna Chand Paidi

Background: Acute kidney injury (AKI) is a common and serious clinical condition associated with significant morbidity, mortality, prolonged hospital stay, and increased healthcare burden. Early identification of etiological factors and severity is essential for timely intervention and improved outcomes. Methods: A hospital-based analytical cross-sectional study was conducted among 150 patients with AKI admitted to a tertiary care hospital over 18 months. Patients fulfilling acute kidney injury network (AKIN) diagn …

29.08.2026journal-article

Genes

Functional Characterization of the PAX8 p.Leu264Pro Variant Identified in a Patient with a Müllerian Duct Anomaly

Lin He, Liangzhe Li, Yuxiao Li, Yujun Sun, Zhi Zheng, Chunfang Chu, Lin Li

Background/Objectives: Müllerian duct anomalies (MDAs) are congenital structural abnormalities of the female reproductive tract with heterogeneous and incompletely defined genetic contributions. PAX8 is a developmental transcription factor implicated in thyroid and urogenital development. This study assessed the functional consequences of a rare PAX8 variant identified by whole-exome sequencing (WES) in an MDA cohort, without presuming a causal relationship. Methods: WES was performed in 150 patients with MDAs. The …

29.08.2026journal-article

International Journal of Environmental Research and Public Health

Non-Combustible Nicotine Use Among Amateur and University Athletes: Prevalence, Patterns and Reasons—A Scoping Review

Nguyen Hoang, Melis Selamoglu, Isabella Papadopoulos, Chi Lao, Holly Wild, Susan Kotwas, Ines Rio, Kim Turudia, Dale Cridland, Chris Barton

Background: Nicotine exposure is increasingly occurring through non-combustible products such as electronic cigarettes and nicotine pouches. Although sport participation is often considered protective against substance use, nicotine use appears to be increasingly normalised within performance-oriented sporting environments. Methods: This scoping review synthesised evidence on non-combustible nicotine use among amateur and university athletes. Following Joanna Briggs Institute (JBI) methodology and Preferred Reporti …

29.08.2026journal-article

Dentistry Journal

Clinical and Esthetic Outcomes of Vestibular Socket Therapy: A Systematic Review and Meta-Analysis

Yasser Sherif Soliman, Nadine Gräfin von Krockow, Fatma E. A. Hassanein, Mihad Ibrahim, Abdelsalam ElAskary, Hossam Ismail

Background/Objectives: Vestibular socket therapy (VST) is a minimally invasive technique for immediate implant placement (IIP) in compromised extraction sockets that reconstructs the deficient buccal plate while preserving the crestal soft tissue. Despite growing clinical adoption, the randomized evidence on its predictability and biological performance remains limited. Methods: Following PRISMA 2020 and prospectively registered in PROSPERO (CRD420261288724), PubMed/MEDLINE and EMBASE were searched to January 2026 …

29.08.2026journal-article

Diagnostics

Impact of Associated Infections on the Clinical Course and Risk-Stratification Profile of Pulmonary Embolism: Comparative Analysis Using PESI, Wells, Padua, and IMPROVE Scores

Daniela Nicoleta Crisan, Raluca Dumache, Talida Georgiana Cut, Alexandra Herlo, Marius Florentin Popa, Lucian-Flavius Herlo, Nina Ivanovic, Andreea Nelson Twakor, Gabriela-Florentina Țapoș, Adelina Raluca Marinescu

Background: Pulmonary embolism (PE) remains a major cause of cardiovascular morbidity and mortality, and associated infections may modify its clinical course. This study evaluated the impact of viral infections on pulmonary embolism severity, mortality, and the performance of established risk scores. Methods: This retrospective observational study included 729 patients with confirmed PE admitted between January 2020 and December 2025. Patients were grouped according to the presence of associated infections. We anal …

29.08.2026journal-article

Rheumatology International

Mental- and physical-health comorbidity are strongly associated in idiopathic inflammatory myopathies: a multinational cross-sectional e-survey

Samuel Katsuyuki Shinjo, Lekshmi Minikumari Rahulan, Meera Shah, Anchit Chauhan, Suhana Hussain, Paula Jordan, Meghna Lama, Oladipo Kunle Afolayan, Vincenzo Venerito, Tamar B. Rubinstein, Ioannis Parodis, Elena Nikiphorou, Joanna Makowska, Aleksandra Opinc-Rosiak, Rada Miskovic, Marcin Milchert, Dimitri Luz Felipe da Silva, COVAD Study Group, Odirlei Andre Monticielo, Simone Appenzeller, Vidya Sadanand Limaye, Binit Vaidya, Ai Lyn Tan, Nelly Ziade, Tsvetelina Velikova, Abraham Edgar Gracia-Ramos, Masataka Kuwana, Johannes Knitza, Ashima Makol, Carlos Enrique Toro Gutiérrez, Carlo Vinicio Caballero-Uribe, Dzifa Dey, Jessica Day, Laura Andreoli, Chris Wincup, Nicola Dalbeth, Gerd-Rüdiger Burmester, Guochun Wang, Lorenzo Cavagna, Vahed Maroufy

Abstract Comorbidities are associated with morbidity, function, and survival in idiopathic inflammatory myopathies (IIM), but subtype-specific patterns, mental-physical comorbidity relationships, and patient-reported outcomes remain incompletely characterized. We hypothesized that multimorbidity in IIM is heterogeneous, associated with demographic, clinical, and psychosocial factors, and linked to differences in physical function and fatigue. We studied 1028 adults with self-reported, specialist-confirmed IIM. Como …

29.08.2026journal-article

Scientific Reports in Medicine

Evaluation of patients who underwent invasive mechanical ventilation in a pediatric intensive care unit: a prospective study

Sıdıka Canan Atasoy, Rıza Dinçer Yıldızdaş, Özden Özgür Horoz, Ergin Atasoy, Faruk Ekinci, Sinem Sarı Gökay, İlknur Tolunay

Objective: To evaluate the use of invasive mechanical ventilation (MV) during a one-year period (2015–2016) in a pediatric intensive care unit (PICU), identify the most common complications and mortality rates, and compare study-period practices with more recent evidence to characterize changes in pediatric MV management over the past decade. Method: Among 781 patients followed in the PICU of Çukurova University Faculty of Medicine between February 2015 and February 2016, 173 patients who underwent invasive MV were …

29.08.2026journal-article

Journal of Clinical Monitoring and Computing

A comparison between two indices derived from automated pupillometry devices

Carlotta Bandoni, Khalil Mounir, Francesca Iannuzzi, Andrea Berardino, Fabio Tarantino, Mohammed Rabi Andaloussi, Fabio Silvio Taccone, Denise Battaglini, Nicolo ’ Antonino Patroniti, Chiara Robba

Abstract Automated pupillometry provides a standardised, quantitative, highly reproducible measurement of the pupillary light reactivity and other pupillary variables. The Neurologic pupillary index (NPi) has shown good prognostic value in patients with acute brain injury and cardiac arrest. However, few data on the comparison of NPi with a recently introduced index (quantitative pupillary index, QPI) are available. To compare the performance of two commercially available automated pupillometry devices, and in part …

29.08.2026journal-article

Journal of Immigrant and Minority Health

Preparing Resident Physicians to Protect Immigrant Patient Rights During Immigration Enforcement Encounters: A Pre–Post Educational Intervention

Simran Rahi, Safia Ansari, Emily Gordon

Abstract Immigration enforcement increasingly intersects with healthcare delivery, creating clinical situations that may affect immigrant patients’ access to care, trust in healthcare institutions, and interactions with physicians. Despite these challenges, formal training on immigrant patient rights and physician responsibilities during immigration enforcement encounters remains limited. We evaluated the impact of a case-based educational intervention on resident physician preparedness for these encounters. We con …

29.08.2026journal-article

Journal of Policy and Development Studies (JPDS)

Academic Collaboration and Technological Innovation in Kenyan Public Universities: An Innovation Intermediary Perspective

Caroline Awuor Odhuno, Kenneth Lawrence Wanjau, Richard Kiai

Kenya’s public universities are central to the country’s innovation agenda, yet weak linkages with industry continue to constrain technology transfer. This study examines how academic collaboration influences technological innovation and evaluates the dual role of innovation intermediaries as mediators and moderators in this relationship. A cross‑sectional survey design was adopted, with a census of all 66 chartered universities and stratified random sampling of industry and intermediary respondents, yielding 212 p …

29.08.2026journal-article

Western Journal of Emergency Medicine

Efficiency and Humanism: The Impact of the Humanistic Charting Tool on Patient Experience in the Emergency Department

Namrata Garg, Omid Boozarpour, Jose Alaras, Ivy Tran, Christopher R. Peabody, Nicholas Stark

Introduction: Emphasis on documentation challenges clinicians to strike a balance between efficiency and individualized care, often leading to the depersonalization of patient interactions. The Humanistic Charting Tool (HCT) addresses this by integrating the patient’s voice into the electronic medical record (EHR). The objective of this study was to examine whether use of the HCT during emergency department (ED) visits is feasible and improves key patient experience metrics. Methods: The study took place in an urba …

29.08.2026journal-article

Indonesian Journal of Electronics, Electromedical Engineering, and Medical Informatics

Enhancing Low-Resource Healthcare Chatbots via Multi-Stage Data Augmentation and IndoBERT Fine-Tuning

Ahmad Wahyu Rosyadi, Taufiqur Rohman, Moh. Rizki Fajar, Muhammad Qomaruz Zaman, Siti Ma'shumah

Indonesian healthcare question-answering (QA) systems often operate in low-resource settings and must handle substantial linguistic variability in real-world user queries, including paraphrasing, informal expressions, and implicit intent. These challenges are compounded by limited annotated healthcare data and the diverse ways patients express similar medical needs in everyday language, causing QA models to rely heavily on surface-level wording. This study proposes a new multi-stage data augmentation method to impr …

29.08.2026journal-article

Canadian Public Administration

The Relational Character of Canadian Nation‐Building Infrastructure in the 21 st Century

Alaz Munzur, Katharina Koch

Abstract Infrastructure development is central to Canada's nation‐building process. This article argues that the federal government has recalibrated its nation‐building mandate from unilateral state command to relational orchestration. Through thematic analysis of thirty‐eight policy documents related to three federal infrastructure plans (2007–2016), we show that “nation‐building infrastructure” has evolved from large‐scale projects to an umbrella term encompassing community‐focused initiatives and both hard and s …

29.08.2026journal-article

The Nursing Scope

Perceptions, Perceived Efficacy, and Factors Influencing the Objective Structured Clinical Examination Among Nursing Students at the University of Ibadan

Chizoma Ndikom

Background: The Objective Structured Clinical Examination (OSCE) has been widely adopted in health professions education because of its objectivity, standardisation, and structured approach to assessing clinical competence. Despite its widespread use, limited evidence exists regarding nursing students’ perceptions of the OSCE, its perceived efficacy, and the factors influencing their performance. Aim: To assess nursing students’ perceptions, perceived efficacy, and factors influencing performance in the Objective S …

29.08.2026journal-article

International Journal of Environmental Research and Public Health

Bouldering Psychotherapy for Mental Health in Brazil: Preliminary Evidence from a Mixed-Methods Controlled Study

Pedro Carvalho Frulane de Souza, Tatiana Arenas Mora, Tiago Arruda Sanchez, Erick Francisco Quintas Conde

Previous studies have shown that Bouldering Psychotherapy (BPT), an emerging integrative intervention combining bouldering with psychotherapeutic techniques, may promote improvements in mental health and well-being. This pilot study aimed to examine the effects of BPT on symptoms of depression and anxiety in a Brazilian population and explore participants’ perceptions of its psychological and social impacts. Eleven participants completed an eight-week BPT program and were compared with a matched control group. Symp …

29.08.2026journal-article

Diagnostics

Clinical Repeatability and Inter-Method Agreement of VITA Easyshade Advance 4.0 and Rayplicker Cobra for Tooth Shade Determination: An Exploratory Cross-Sectional Study

L. Portero-Ruz, M. Valor-Priego, A. Martín-Vacas, M. M. Paz-Cortés, J. Mena-Álvarez, C. Rico-Romano

Background: Instrumental shade determination may reduce some sources of subjectivity associated with visual shade selection, but device repeatability and interchangeability remain clinically relevant concerns. Objective: The aim of this study was to evaluate the reproducibility and clinical utility of two spectrophotometric devices (Easyshade and Rayplicker Cobra) for tooth shade measurement and selection. Methods: In total, 35 adults were evaluated at seven predefined maxillary tooth regions: the cervical, middle, …

29.08.2026journal-article

African Journal of Primary Health Care & Family Medicine

Assessing the effectiveness of the patient referral system in remote Zambia: A case study of Mbala District

Austine Dolopo

Background: Effective patient referral systems are vital for ensuring timely access to advanced healthcare services, particularly in remote areas. In Zambia’s rural districts such as Mbala, the referral system faces critical challenges, including poor road networks, limited ambulance services, unreliable communication infrastructure and a lack of medical personnel at lower-level facilities. These issues contribute to delays, preventable complications, and increased patient morbidity and mortality. Aim: This study a …

29.08.2026journal-article

Pediatric Research

Serum and urinary D-lactate in pediatric intestinal failure: clinical associations and reference values

Rita Halašová, Rana Ibrahim, Stanislava Balogová, Radek Štichhauer, Alena Tichá, Radomír Hyšpler, Vladana Skutilová, Filip Fencl, Kateřina Bajerová, Eva Karásková, Mária Véghová-Velgáňová, Peter Szitányi, Jan Schwarz, Monika Koudová, Rafael Doležal, Vanda Mečiarová, Jan Melek

Abstract Background D-lactate, produced by intestinal microbiota or derived from the methylglyoxal pathway and diet, is converted by D-lactate dehydrogenase (LDHD) to pyruvate, with several known pathogenic variants of the gene. This study compared serum and urinary D-lactate concentrations across five patient groups and established reference values in healthy children. Methods In this cross-sectional study, 341 serum and urine samples from 129 pediatric patients were analyzed. The cohort comprised patients receivi …