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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

Philosophical Transactions of the Royal Society B: Biological Sciences

Functions of the EGFR in health and disease

Thomas Bauer, Martin Holcmann, Maria Sibilia

Abstract The epidermal growth factor receptor (EGFR) is a critical mediator of cellular physiology, and its deregulation is implicated in a broad spectrum of pathological conditions, ranging from skin disorders to epithelial malignancies and brain tumours. Although lack of EGFR signalling primarily affects skin and brain development and tissue homeostasis, aberrant EGFR activation through overexpression or mutation converts the receptor into a potent oncogenic driver. This occurs particularly in human cancers such …

1 Zitationen
27.08.2026journal-article

Symmetry

PNS-WINGS-AHP–EWM Integrated Framework for Multi-Criteria Decision Analysis: An Application-Oriented Decision Framework in Digital Agriculture

Yawen Wang, Kecheng Zhang

Digital-agriculture development increasingly requires multi-criteria decision analysis (MCDA) approaches to evaluate complex and interrelated influencing factors. However, existing methods often face difficulties in representing uncertain expert judgments, capturing inter-factor influence structures, and integrating complementary weighting information. To address these challenges, this study develops an integrated Pythagorean Neutrosophic Sets (PNS)–Weighted Influence Non-linear Gauge System (WINGS)–Analytic Hierar …

27.08.2026journal-article

Journal of Health Organization and Management

Hospital work environment and perceived workforce productivity: a structure–process–outcome perspective from Thailand's healthcare sector

Zulfiqar Ali Jumani, Tachaya Sangkakool, Ruengrumpa Intaraksa, Chila Kaewpraek, Thitika Kaewsomwong

Purpose This study examines how hospital environmental conditions influence perceived workforce productivity through the mediating roles of organizational support and job satisfaction. Grounded in Donabedian's structure–process–outcome (SPO) framework and informed by motivational theory, the study conceptualizes productivity as an organizational outcome shaped by structural and psychosocial processes rather than as a purely technical measure. Design/methodology/approach A quantitative, cross-sectional survey was co …

27.08.2026journal-article

Revista ft

Da gestão tradicional à gestão inteligente: como automação, dados e inteligência artificial estão transformando a administração

Mayara Pires dos Santos Freitas

Administration is undergoing a transformation driven by advances in automation, data analysis, and artificial intelligence. Processes that previously depended on manual controls and repetitive tasks are being replaced or complemented by tools capable of organizing information, optimizing activities, and supporting decision-making. This article presents a reflection on the transition from traditional management to more intelligent management, highlighting that the adoption of technology, by itself, does not guarante …

27.08.2026journal-article

JAMA Network Open

A Multilevel Intervention to Identify Individuals for Genetic Testing and Treatment

Kirsten A. Jorgensen, Nuria Agusti, Tara Coffin, Karla Barajas, Maria D. Iniesta, Erica M. Bednar, Alexa Kanbergs, Roni Nitecki Wilke, Isabel Beshar, Sara Pirzadeh-Miller, Sayoni Lahiri, Kathy Pratt, Kristofer Jennings, Heidy Bosch, Charles A. Leath, Beth Karlan, Melissa Frey, Ravi Sharaf, Karen Lu, J. Alejandro Rauh-Hain

Importance Cascade genetic testing (CGT) is a key strategy for cancer prevention in families with hereditary breast and ovarian cancer syndrome (HBOC) and Lynch syndrome (LS), yet uptake among at-risk relatives remains persistently low, particularly in medically underserved populations where structural and informational barriers limit access to genetic services. Objective To evaluate the feasibility and preliminary effects of IGNITE-TX (Identifying Individuals for Genetic Testing and Treatment), a scalable, bilingu …

27.08.2026journal-article

Kōtuitui: New Zealand Journal of Social Sciences Online

‘Reflecting Humanity, Or Lack of It’: Ancestral Intelligence and Whakapapa Authority in Wāhine From Gang Whānau

Paora Moyle

The body is where ancestral intelligence operates, where colonial harm has accumulated over generations, and where healing becomes physically possible. Mana Wāhine scholarship has theorised wāhine Māori authority as ancestral and structural, transmitted through whakapapa and whenua. How that authority lives in the body has remained under‐theorised. This article works from pūrākau shared by 20 wāhine Māori from gang whānau over 2 years of engagement, gathered using a Mana Wāhine pūrākau methodology. Four expressions …

27.08.2026journal-article

Clinical and Translational Gastroenterology

Diagnostic Performance of Six Tests for Helicobacter pylori Infection in Peptic Ulcer Bleeding: A Prospective Head-to-Head Comparison

Tanawat Geeratragool, Thanapat Atthakitmongkol, Supathep Tansirichaiya, Pubet Weeranawin, Somchai Leelakusolvong, Monthira Maneerattanaporn

Background: Rapid urease test (RUT) is widely used for diagnosing Helicobacter pylori (HP) because it is inexpensive and practical. However, its accuracy is reduced in peptic ulcer bleeding (PUB). We prospectively performed a head-to-head comparison of diagnostic tests in the same patients to evaluate their performance in this setting. Methods: After endoscopic hemostasis, gastric biopsies were obtained for RUT, histology, and PCR. Blood samples were collected for current infection marker (CIM) and anti-urease anti …

27.08.2026journal-article

Global Journal of Engineering and Technology Research

Predictive Simulation and Early Warning in Flood Digital Twins: A Systematic Review of AI Model Performance, Warning Lead Times, And Operational Deployment

Lydia Dede Obeng

Flooding is the most economically destructive natural hazard in the United States, with annual losses exceeding $60 billion and risk concentrated unevenly across communities and regions. This systematic review synthesizes evidence on AI-enhanced digital twin architectures for U.S. flood infrastructure management. Following PRISMA 2020 guidelines, a search across six academic databases (2020–2025) identified 3,847 records, of which 94 studies met inclusion criteria. The findings are clear. Long Short-Term Memory (LS …

27.08.2026journal-article

Population, Space and Place

Boomerang Young Adults in Seoul, South Korea: Residential Pathways, Health and Social Attitudes

Gum‐Ryeong Park, Jiawei Wu

ABSTRACT Leaving the parental home is a key transition to adulthood. However, recent sociodemographic changes have produced more diverse residential pathways such as delayed home‐leaving or returning to the parental home (‘boomerang movers’). While prior research has focused on the characteristics and determinants of these patterns, few studies have examined how various residential pathways are related to trajectories of health and social attitudes in Korea. We used longitudinal data from the annual Seoul Young Adu …

27.08.2026journal-article

Clinical Journal of Health Sciences

Investigation of the Relationship Between Psychopathological Symptoms, Acculturation, and University Adjustment Among Students from Eastern and Western Türkiye Studying in the TRNC

Merve Nehir Kurt, Mehmet Çakıcı, Atakan Taşkıran

The aim of this study was to compare the acculturation attitudes, university adjustment levels, and psychopathological symptoms of university students from the eastern and western regions of Türkiye studying in the Turkish Republic of Northern Cyprus (TRNC), and to examine the relationships among these variables. This descriptive cross-sectional study included a total of 100 university students enrolled at Near East University, comprising 50 students from the eastern regions and 50 students from the western regions …

27.08.2026journal-article

Tijdschrift voor Urologie

Klinische kenmerken en chirurgische behandeling van urogenitale endometriose: een retrospectief cohortonderzoek

Hanzhe Dong, Eefje Oude Lohuis, Johanna M. A de Bruin, Bob Theodoor Merks

Samenvatting Endometriose kan verscheidene orgaansystemen aantasten. Urogenitale endometriose (UGE) is een zeldzame vorm van diepe endometriose met betrokkenheid van blaas en/of ureters. In dit retrospectieve cohortonderzoek werden 80 vrouwen met UGE geïdentificeerd onder 1.568 geopereerde patiënten met diepe endometriose (2018–2024), overeenkomend met een prevalentie van 5,1 %. Blaasendometriose kwam voor bij 34 patiënten, ureterbetrokkenheid bij 32 en gecombineerde ziekte bij 14. Dysurie trad vaker op bij blaasbe …

27.08.2026journal-article

BMC Psychology

Associations of war-related displacement and reintegration with mental health and academic experiences among university students in Lebanon: a cross-sectional study

Samer A Kharroubi, Rouba Ballout

Abstract Background The escalation of war in Lebanon has severely impacted many aspects of daily life, with university students particularly affected in terms of their mental health and academic experiences. This study aimed to examine the effects of the war, with a focus on displacement and reintegration, on students’ mental health and academic outcomes, using the American University of Beirut (AUB) as a case study. Methods Data was collected from AUB students using a cross-sectional, self-administered online surv …

27.08.2026journal-article

Journal of Information Technology and Digital World

AdvaSell: An AI-Powered Dynamic Pricing System Using Linear Regression for E-Commerce Platforms

Sadeesh S., Aakash Lingam M.

The development of dynamic pricing that considers the conditions of the market at the time of purchase has turned out to be one of the major tasks for online stores. In this paper, we present the implementation of AdvaSell, a price prediction system, which is based on linear regression and recommends product prices according to its category, brand, stock, history of purchases, and seasonality. On a random test subset of approximately 30,000 records from an e-commerce dataset, the model scored 0.9945 R², suggesting …

27.08.2026journal-article

Eastern Europe: Economy, Business and Management

DIGITAL TRANSFORMATION OF THE FINANCIAL ARCHITECTURE OF INCLUSIVE TERRITORIAL DEVELOPMENT: MECHANISMS FOR VETERAN REINTEGRATION AND POST-WAR RECOVERY OF UKRAINE

Anna Ivanova

The article examines the theoretical and applied aspects of developing a digital financial ecosystem for inclusive territorial development amid digitalization, decentralization, and Ukraine’s post-war recovery. It is substantiated that growing socio-economic challenges, the expanding role of local self-government, and the need to support the social and economic reintegration of war veterans require modernizing approaches to financing territorial development. The study finds that the financial capacity of territoria …

27.08.2026journal-article

LANCAH: Jurnal Inovasi dan Tren

Artificial Intelligence and Psycholinguistics: How Do Large Language Models Represent Human Language Processes? A Systematic Review

Astuty Astuty

The rapid development of large language models (LLMs) has fundamentally transformed contemporary perspectives on language representation and processing. Models such as GPT, Gemini, Claude, Llama, and DeepSeek demonstrate remarkable capabilities in language comprehension, generation, translation, summarization, and reasoning, raising important questions regarding their relationship to human language processing. While psycholinguistic theories traditionally explain language through cognitive mechanisms involving perc …

27.08.2026journal-article

Health Research Journal of Indonesia

Faktor-Faktor yang Mempengaruhi Kepatuhan Terhadap Pengobatan di Komunitas Pedesaan : Peran Pengetahuan, Dukungan Keluarga, dan self eficacy

Raya Raya, Bayu Budi Laksono

Kepatuhan terhadap pengobatan merupakan faktor penting dalam pengendalian hipertensi. Faktor kognitif dan psikososial, seperti pengetahuan, dukungan keluarga, dan self-efficacy, diduga berperan dalam membentuk kepatuhan pasien, khususnya di komunitas pedesaan. Tujuan penelitian ini adalah untuk menganalisis hubungan pengetahuan, dukungan keluarga, dan self-efficacy dengan kepatuhan terhadap pengobatan pada pasien hipertensi di komunitas pedesaan wilayah kerja Puskesmas Lamunti. Penelitian menggunakan desain survei …

27.08.2026journal-article

ICEETE Conference Series

Entrepreneurial Orientation and Business Potential toward MSME Financial Performance through Managerial based Entrepreneur Finance during Digital Transformation

Intan Shaferi, Alisa Tri Nawarini, Cut Misni Mulasiwi

This study focus at how being entrepreneurial and having good business potential affect the financial performance of small businesses, for example micro, small, and medium enterprises. It also considers how the way managers handle business finance plays a role in this relationship, especially in the context of digital transformation. As digital tools keep changing how businesses work, small and medium-sized enterprises need to improve their business skills and better manage their money to keep their finances stable …

27.08.2026journal-article

Journal of the American Heart Association

Socioeconomic Position in Early Life and Childhood Cardiovascular Health Measures: An International Cross‐Cohort Study

Kavindi Gamage, Susanna Pätsi, Tong Chen, Kate Mooney, Sylvain Sebert, Naomi Priest, Toby Mansell, David Burgner, the Barwon Infant Study Investigator Group

Background Cardiovascular disease is socioeconomically patterned, and risk accrues from early life. Evidence in younger populations is scarce. We investigated the extent to which early life socioeconomic position is associated with cardiovascular health in children and adolescents, and the extent of mediation by body mass index. Methods We analyzed 5 longitudinal birth cohorts: BIS (the Barwon Infant Study; Australia; mean age 4.1 years; n=708); BiB (Born in Bradford; United Kingdom; mean age 9.3 years; n=4576); LS …

27.08.2026journal-article

International Journal of Consumer Studies

Letting AI Resurrect Your Loved Ones? Exploring People's Intention to Adopt Digital Resurrection Technology

Changyong Liang, Peiyu Zhou, Yuguang Xie, Junhong Zhu

ABSTRACT Digital resurrection technology, which uses artificial intelligence and multimodal synthesis to recreate the likeness, voice, and behaviors of deceased individuals, has attracted growing attention for its potential value in commemoration, emotional healing, cultural preservation, and education. However, ethical, privacy, and moral concerns may hinder consumer adoption, making it important to understand the psychological mechanisms underlying adoption intention. Grounded in the dual factor model of technolo …

27.08.2026journal-article

Tạp chí Khoa học Đại học Công Thương

ASSESSING THE IMPACT OF BLOCKCHAIN ON THE PERFORMANCE AND SECURITY OF DIGITAL CONSUMER LENDING SYSTEMS

Ho Thanh Tri, Le Hoang Minh Khue, Le Dinh Van, Tran Gia Linh, Vo Nguyen Thien Kim, Tran Phuong Dinh

As the digital economy rapidly develops, quick access to capital has become a critical survival factor for individuals intending to start a new business. However, under traditional bank lending systems, these aspiring entrepreneurs face significant barriers due to complex financial documentation requirements and stringent credit history checks. Drawing on the Technology Acceptance Model (TAM), this study investigates factors influencing users’ adoption of blockchain-enabled digital lending platforms among individua …

27.08.2026journal-article

Tạp chí Khoa học Đại học Công Thương

ARTIFICIAL INTELLIGENCE ADOPTION IN ENTERPRISES: A LAYERED CAPABILITY FRAMEWORK FOR EMERGING ECONOMIES

Vu Van Diep

Artificial Intelligence (AI) is increasingly recognized as a foundational technology for enterprise competitiveness in the digital economy. However, limited research explains how AI capabilities create enterprise value in emerging economies with uneven digital readiness. This study synthesizes the mechanisms of AI-driven value creation and examines structural barriers to enterprise AI adoption in Vietnam. Using a qualitative conceptual research design based on secondary data, the study integrates the Resource-Based …

27.08.2026journal-article

Discover Oncology

Ovarian cancer tumor immune microenvironment and its clinical trial implications

Barbora Vavrušáková, Renata Bartošová, Michal Hendrych, Tomáš Kazda, Lukáš Moráň, Marek Svoboda

Abstract Ovarian cancer is the most lethal gynecologic malignancy, primarily because of late-stage diagnosis, rapid disease progression, and marked molecular and immunologic heterogeneity. It remains the leading cause of gynecologic cancer-related death, affecting approximately 1 in 70 women in developed countries over their lifetimes. Tumor development and progression are orchestrated within the tumor immune microenvironment, a dynamic and complex structural niche that supports malignant transformation and immune …

27.08.2026journal-article

International Journal of Humanities and Social Science

Decoding Crypto Advertising: How Teenagers Interpret Digital Cryptocurrency Promotions on Social Media

Krishiv Arora

This paper investigates how cryptocurrency advertising and social media ecosystems shape Indian teenagers’ perceptions of risk, trust and opportunity in digital assets. Against a backdrop of low youth financial literacy and rising Gen Z participation in crypto investing globally, understanding how young people interpret persuasive financial content is increasingly relevant. The study addresses a gap in existing work, which largely focuses on adult retail investors in developed markets and text-heavy platforms, by e …

27.08.2026journal-article

JGH Open

Plant and Animal Protein Sources in Inflammatory Bowel Disease: Current Evidence and Clinical Implications

Mustafa Mohamedrashed, Ayushi Chauhan, Vaios Svolos, Abhinav Vasudevan, Chu K. Yao

ABSTRACT With the consumption of protein consumption increasing globally, there are gaps in our understanding of the differences in protein sources, particularly between animal and plant proteins and their recommendations for patients with Inflammatory Bowel Disease (IBD). This narrative review synthesizes current evidence of how animal and plant proteins differentially exert physiological effects, influence IBD risk, and outcomes. First, protein sources vary in their amino acid profiles, co‐existence with other nu …