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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
27.08.2026journal-article

Health Research Journal of Indonesia

Hubungan Pengetahuan dengan Kepatuhan Minum Obat Hipertensi di Wilayah Kerja UPT Puskemas Mantangai, Kalimantan Tengah

Eka Fitriani, Musthika Wida Mashitah

Hipertensi merupakan penyakit kronis yang memerlukan kepatuhan minum obat secara berkelanjutan untuk mencegah komplikasi. Pengetahuan yang memadai mengenai hipertensi dan pengobatannya berperan penting dalam meningkatkan kepatuhan pasien terhadap terapi sehingga tekanan darah dapat dikendalikan secara optimal. Penelitian ini bertujuan untuk mengetahui hubungan antara pengetahuan dengan kepatuhan minum obat pada pasien hipertensi di Wilayah Kerja Puskesmas Mantangai. Penelitian ini menggunakan desain kuantitatif den …

27.08.2026journal-article

The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences

Reproductive life course histories and menopausal outcomes at midlife: Evidence from the National Longitudinal Study of Adolescent to Adult Health

Brianah M McCoy, Stephanie M Koning, Kathleen Mullan Harris, Lauren Gaydosh

Abstract Objectives Menopause is a heterogeneous transition that varies in timing and type, yet population-based research rarely considers how reproductive life course experiences shape menopausal outcomes. This study examines whether reproductive timing, reproductive history, and reproductive health across adolescence and adulthood are associated with menopausal status, early menopause, and surgical menopause at midlife. Methods Using data from women in Waves I–VI of the National Longitudinal Study of Adolescent t …

27.08.2026journal-article

Molecules

Explainable Artificial Intelligence Assisted Modeling of Malachite Green Adsorption onto SBA-15–Zn–Fe Composite

Memduha Ergüt, Salih Ozbay, Seda Karateke, Metin Zontul

Dye-containing industrial effluents pose substantial risks to aquatic ecosystems. In this study, a material prepared using the stated SBA-15–Zn–Fe synthesis procedure was evaluated for malachite green (MG) removal and modeled using machine-learning and explainable artificial intelligence techniques. The dataset comprised 315 experimental observations covering initial MG concentrations of 100–500 mg L−1, adsorbent concentrations of 0.5–3.0 g L−1, pH values of 5–9, temperatures of 25–45 ∘C, and contact times of 0–360 …

27.08.2026journal-article

Research in Psychotherapy: Psychopathology, Process and Outcome

Psychological adaptation and health-related quality of life in inflammatory bowel disease: a 5-year follow-up study

Gabriella Martino, Emanuele M. Merlo, Carmelo M. Vicario, Federica Bellone, Clara De Francesco, Ulla Feldt-Rasmussen, Antonino Catalano, Walter Fries, Orlando Silvestro

Inflammatory bowel disease (IBD), encompassing Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic immune-mediated gastrointestinal condition in which long-term care increasingly involves patient-reported health, emotional functioning, and psychological adaptation. Because psychological adaptation may not parallel clinical remission, this 5-year longitudinal study examined changes in psychopathological symptoms, alexithymia, coping strategies, and health-related quality of life (HR-QoL) in 73 outpatients …

27.08.2026journal-article

Neuro-Oncology

145 Implementing Vorasidenib in Clinical Practice: A Single-Centre Real-World Service Evaluation

Brooke Smart, Lorna Raymond, Antonia Creak, Liam Welsh, Ella Nicklin, Matteo Isolani, Ozofu Omuemu, Francesca Solda, Nicola Rosenfelder

Abstract Introduction The phase 3 INDIGO trial demonstrated significantly improved progression-free survival with Vorasidenib in patients with residual/recurrent IDH-mutant grade 2 oligodendroglioma and astrocytoma, supporting its integration into routine neuro-oncology practice. We undertook a real-world service evaluation at the Royal Marsden Hospital to assess toxicity, monitoring burden, and implications for wider UK implementation ahead of the anticipated appraisal by the National Institute for Health and Care …

27.08.2026journal-article

Sensors

Improved Fusion of Optical Flow and Dead Reckoning for UAV Navigation Using Digital Terrain Models and Data-Driven Velocity Correction

Jakub Walczak, Piotr Targowski, Szymon Chmielewski, Sebastian Łeska, Janusz Furtak

Accurate velocity estimation in GPS-denied environments remains a core challenge for autonomous unmanned aerial vehicle (UAV) navigation. Our previous work demonstrated that fusing optical flow (OF) with dead reckoning (DR) substantially reduces position drift compared to inertial-only solutions. However, velocity estimates derived from dense optical flow are degraded by two systematic effects: (1) incorrect metric scaling when the camera footprint covers heterogeneous terrain types—particularly at forest–field tra …

27.08.2026journal-article

Journal of Applied Clinical Medical Physics

Evaluating the preoperative diagnostic value of 99m Tc‐MIBI/ 99m TcO 4 − dual‐isotope SPECT/CT fusion imaging and ultrasonography in suspected primary hyperparathyroidism

Yanmei Li, Danna Hou, Zhehao Lyu, Xingrong Lan, Ziyue Zhang, Yu Lu, Peng Fu, Huiqi Gao

Abstract Background Primary hyperparathyroidism (PHPT) is a common endocrine disorder that often requires surgical intervention. Preoperative localization of parathyroid lesions is critical for successful surgery. This study compares the diagnostic value of 99m Tc‐MIBI/ 99m TcO 4 − dual‐isotope SPECT/CT fusion imaging and ultrasonography (US) in patients with suspected PHPT, and explores the correlation between lesion volume and preoperative serum biochemical markers. Objective This study aimed to assess the preope …

27.08.2026journal-article

Transactions on Social Science, Education and Humanities Research

The Legal Path of Digital Technology Driving the Modernization of Border Ethnic Affairs Governance

Kaixin Zheng, Li Wei

The modernization of border ethnic affairs governance driven by digital technology is an inevitable requirement arising from the overlapping strategies of national governance modernization and Digital China construction. Based on the three-dimensional analytical framework of "technology-institution-value", this paper systematically interprets the legal basis and practical landscape of digital empowerment for border ethnic affairs governance, analyzes the in-depth legal dilemmas faced by the current governance trans …

27.08.2026journal-article

Journal of Central Banking Theory and Practice

Central Bank Digital Currencies and Bank Deposit Dynamics: Evidence from Cross-Country Difference-in-Differences Analysis

Piotr Misztal

Abstract The emergence of central bank digital currencies (CBDCs) represents one of the most significant innovations in contemporary monetary systems. As central banks explore digital forms of sovereign money, an important question concerns how CBDC introduction may affect the structure of financial intermediation, particularly the role of commercial bank deposits. Because CBDCs constitute a direct claim on the central bank, their availability may alter the allocation of liquid assets held by households and firms a …

27.08.2026journal-article

Clinical Journal of the American Society of Nephrology

Proteinuria and Kidney Function Trajectories in Patients with Advanced CKD

Cheol Ho Park, Hyun Jun Hong, Hyung Woo Kim, Jung Tak Park, Tae Ik Chang, Tae-Hyun Yoo, Sue K. Park, Jung Soon Kim, Kyu-Beck Lee, Jong Cheol Jeong, Kook-Hwan Oh, Amanda H. Anderson, Wei Yang, Jordana B. Cohen, Mahboob Rahman, Shin-Wook Kang, Seung Hyeok Han, on the behalf of CRIC Study and KNOW-CKD Investigators

Introduction: While urine protein-to-creatinine ratio (UPCR) is more commonly used than urine albumin-to-creatinine ratio in routine care, and particularly in low-resource settings; its association with kidney function decline and projected time to reach a kidney failure estimated glomerular filtration rate (eGFR) threshold in advanced chronic kidney disease (CKD) remains underexplored. Methods: We analyzed 2,727 participants with eGFR 15–45mL/min/1.73 m 2 without kidney replacement therapy (KRT) from the Chronic R …

27.08.2026journal-article

Clinical Cancer Research

Adrenergic regulation of cancer immunity

Jingjing Zhu, Pierre-Hubert Desimpel, Constance Gérard, Benoit J. Van den Eynde

Abstract The nervous and immune systems engage in extensive bidirectional crosstalk that shapes tumor progression and therapeutic response. Among the neuro-immune pathways involved in cancer, adrenergic receptor signaling has emerged as a key regulator of the tumor microenvironment. In this review, we summarize current understanding of the distinct roles of β- and α2-adrenergic receptor signaling in cancer immunity and their therapeutic implications. β2-adrenergic receptor signaling promotes immune suppression by i …

27.08.2026journal-article

Longitudinal and Life Course Studies

Characterising residential mobility during childhood in the United Kingdom: a longitudinal study using linked electronic health records

Nicola Firman, Laura North, Jane Lyons, Marta Wilk, Michael Edwards, Rhodri D. Johnson, Rowena Bailey, Jo Davies, Gill Harper, Carol Dezateux, Richard Fry, Lucy J. Griffiths

Background: Childhood residential mobility (RM) has been associated with adverse health and social outcomes. We examined differences in RM by family size and household composition in two diverse, disadvantaged UK populations. Methods: Using electronic health records (EHRs) and anonymised addresses, we examined if household characteristics are associated with RM in north-east London (NEL) and Wales. We conducted a longitudinal study of 240,509 (51.0 per cent male) and 398,959 (51.3 per cent male) children aged 0–13 …

27.08.2026journal-article

Frontiers in Public Health

Lung cancer screening in occupational settings: a scoping review

Edelqueen Ijeoma Okoro, Helena Keller, Felix Greiner, Jan Heidrich, Volker Harth

Background Lung cancer is the leading cause of cancer-related mortality worldwide. It is often asymptomatic until advanced stages, resulting in delayed diagnosis and poor survival. Screening enables early detection and reduces mortality. Multiple occupational and environmental exposures have been linked to lung cancer, and some guidelines recommend their inclusion in risk assessment. This review aims to map the existing evidence on lung cancer screening (LCS) in occupational settings. Methods This review followed J …

27.08.2026journal-article

Journal of Clinical Medicine

Clinical and Functional Outcomes Following Repeat VA-ECMO in Adults: A Propensity Score–Matched Comparative Study

Kostiantyn Kozakov, Alois Philipp, Maik Foltan, Henrik Heuer, Walter Petermichl, Alexander Dietl, Bernhard Flörchinger, Leopold Rupprecht, Simon Schopka, Christof Schmid, Zdenek Provaznik

Background/Objectives: Evidence on outcomes after repeat VA-ECMO in adults remains limited. This study aimed to compare survival and post-discharge functional outcomes between adults requiring a second VA-ECMO run and propensity-matched patients supported with a single VA-ECMO run and to characterize the clinical course during repeat support. Methods: This is an observational, single-center, retrospective cohort study with a propensity score–matched comparative analysis, conducted at a university tertiary-care refe …

27.08.2026journal-article

Journal of Clinical Medicine

Frequency and Systemic Associations of Focal Low-Trabeculation/Low-Density Intramedullary Jawbone Findings: A Retrospective CBCT Study

Marzena Dominiak, Wojciech Niemczyk, Artur Pitułaj, Witold Świenc, Sebastian Dominiak, Konstanty Sławecki, Łucja Janek, Jacek Matys

Background: This exploratory study assessed the frequency of study-defined focal low-trabeculation/low-density intramedullary findings (FLDIFs) in a selected clinical cohort referred for cone-beam computed tomography (CBCT) and examined their associations with demographic, systemic, and radiographic variables. CBCT depicts mineralized trabecular architecture and relative attenuation but cannot directly demonstrate marrow fat or establish osteonecrosis; FDOJ/MFI were therefore considered only possible interpretation …

27.08.2026journal-article

Frontiers in Psychology

The mediating role of self-perceived health and fitness in the relationship between physical activity and quality of life among individuals with physical disabilities: the moderating effect of self-esteem

Majed M. Alhumaid

Background This study sought to investigate the psychological mechanisms that connect physical activity (PA) to quality of life (QoL) in individuals with physical disabilities (IWPDs). Three hypotheses were tested: (1) self-perceived health and self-perceived fitness mediate distinct indirect associations involving PA, self-perceptions, and QoL; (2) self-esteem moderates the indirect association between PA and QoL through self-perceived fitness; and (3) an integrated model, including PA level, self-perceptions, and …

27.08.2026journal-article

Systems

How Digital Transformation Strengthens Regional Innovation Systems Through Public Research Platforms: Evidence from State Key Laboratories in China

Qianlin Ni, Huaian Wei, Yichi Zhang

Scientific problem. Although digital transformation is widely regarded as a system-level enabler of regional innovation, regions with similar digital investment still display markedly different innovation outcomes, and the organizational channels that convert digital conditions into innovation performance remain insufficiently specified. Aim and method. Using panel data for 30 Chinese provinces from 2014 to 2019, this study conceptualizes State Key Laboratories (SKLs) as a specific institutional form of public rese …

27.08.2026journal-article

HORIZON: Indonesian Journal of Multidisciplinary

Pengaruh Transformasi Digital Terhadap Kinerja Usaha UMK Sektor Fashion Binaan Rumah BUMN Jakarta

Sezara Indah Putri, Tika Koeswandi, Nizza Nadya Rachmani

Digital transformation is a crucial factor for Micro and Small Enterprises (MSEs) in the fashion sector to enhance business performance amidst shifting consumer behaviors and increasingly technology-driven market competition. This study aims to analyze the impact of digital transformation on the performance of fashion-sector MSEs supported by Rumah BUMN Jakarta. A quantitative approach employing descriptive and verificative methods was used. Data were collected via questionnaires distributed to 282 MSE operators us …

27.08.2026journal-article

Technology and Health Care

Redefining coronary revascularization: The emergence of totally endoscopic robotic bypass surgery

Hamad Abdullah Shehab, Syed Mohammad Hussaini, Ibrahim Alabid, Wasim Iyad Alghoul, Mohamedanas Mohamedfaruk Patni

Abstract Totally endoscopic coronary artery bypass (TECAB) is regarded as the most advanced minimally invasive surgical coronary revascularization approach. The objective of this review is to discuss the current evidence on the feasibility, safety, clinical outcomes, and implementation challenges of TECAB, and to investigate whether TECAB can be considered a reproducible and effective alternative to traditional and other minimally invasive approaches for coronary artery bypass. A narrative review was conducted of s …

27.08.2026journal-article

Frontiers in Artificial Intelligence

Deep learning techniques for extreme rainfall prediction: a review of state-of-the-art

Braiton U. Mukhalela, Serestina Viriri, David Ndzi, Michael Gebreslasie, Muhammad Zeeshan Shakir, Naeem Ramzan, Fahad Ayaz, Mary Lynch, Llinos Haf Spencer, Saloshni Naidoo, Nisha Nadesan-Reddy, Ozayr Mahomed, Natalie Dickinson, Fiona Henriquez

Extreme rainfall events (ERES) are among the most challenging hydro-meteorological phenomena to forecast because the complex, nonlinear atmospheric processes involved span multiple spatial and temporal scales and are further intensified by rising climate variability. While Numerical Weather Prediction (NWP) models offer physically consistent representations of atmospheric dynamics, they still struggle to resolve localized convection, rapidly evolving storm systems, and rare, high-intensity precipitation events. Thi …

27.08.2026journal-article

Middle East Policy

Iran's Revolutionary Situation and Digital Authoritarianism: 1979 vs. 2026

Mohsen Askari

Abstract In December 2025, Iran faced weeks of mass protests. However, the Islamic Republic survived after imposing a near‐total internet blackout and a violent crackdown, with reported deaths in the thousands and tens of thousands arrested. Predictions that the regime could collapse prompt a central question: when does protest under digital authoritarianism become a revolution? This article argues that a revolutionary situation requires four mechanisms: coordination of private opposition into mass demonstrations, …

27.08.2026journal-article

PRX Intelligence

Long-Range Machine Learning of Electron Density for Twisted Bilayer Moiré Materials

Zekun Lou, Alan M. Lewis, Mariana Rossi

Moiré superlattices in two-dimensional materials exhibit rich quantum phenomena, but modeling of these systems remains computationally prohibitive. Existing machine learning methods for accelerating density-functional theory can target the prediction of different quantities and often rely on the locality assumption. Here, we train a Gaussian process regression model for symmetry-adapted learning of three-dimensional electron densities exclusively on the electron densities of small displaced bilayer structures and t …

27.08.2026journal-article

PLOS One

Social media addiction, maternal mental health, and children’s oral health behaviours among immigrants

Solmaz Bohlouli, Devarasa Murugeshappa, Babak Bohlouli, Maryam Amin

Objectives Oral health disparities persist among immigrants. Little is known about how social media shapes the socio-psychological environment in which parenting and health behaviours occur. This study examined the link between immigrant mothers’ anxiety and depression and children’s oral health behaviours (OHBs) and evaluated social media addiction as a mediator or moderator. Methods This cross-sectional study recruited immigrant parents of children aged 2–12 years in Edmonton, Canada. Parents completed a question …

27.08.2026journal-article

PLOS Digital Health

Extracting adverse event nature, severity, timelines and resulting interventions from clinical notes of patients receiving CAR-T cell therapy using large language models

Jordan Guillot, Brenda Miao, Arvind Suresh, Madhumita Sushil, Christopher Y. K. Williams, Rohit Vashisht, Tomiko T. Oskotsky, Marina Sirota, Atul J. Butte

Chimeric Antigen Receptor T-cell (CAR‑T) therapy, genetically engineered patient T cells targeting tumor antigens, has transformed care for hematologic malignancies but requires careful tracking of adverse events (AEs) often documented only in unstructured electronic health record (EHR) notes. We evaluated a Large Language Model (LLM)–based approach in UCSF’s secure environment to extract AEs, dates, grades, and interventions within 30 days post‑infusion for six commercial CAR‑T products (2012–2023), benchmarking a …