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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
26.08.2026journal-article

International Journal of Gynecology & Obstetrics

The womb as the cradle of longevity: Perinatal origins of biological aging

Sevim Ozge Ozdemir, Ebru Davutoglu

Abstract The perinatal period is increasingly recognized as an important determinant of biological aging trajectories and disease susceptibility across the lifespan. This narrative review synthesizes current evidence linking intrauterine exposures to adult health outcomes across three biological dimensions: fetal programming, maternal influences, and placental mediation. Evidence from the Dutch Hunger Winter suggests that the timing of gestational exposure—not birth weight alone—might govern programming outcomes. M …

26.08.2026journal-article

World Journal of Cardiology

Cardiovascular aging as a modifiable biological process: Mechanisms, clinical phenotypes, and translational opportunities

Qing Liu, Yi-Fei Wang, Yu Geng, Ping Zhang, Ting-Ting Lv

Cardiovascular aging, a primary driver of the increasing prevalence of cardiovascular disease in older adults, involves a complex biological basis beyond mere chronological age. From a geroscience perspective, aging is now understood as a dynamic and potentially modifiable process, believed to be governed by interconnected molecular hallmarks such as cellular senescence, mitochondrial dysfunction, epigenetic remodeling, telomere attrition, and impaired proteostasis. This review synthesizes recent advancements in ag …

26.08.2026journal-article

Frontiers in Public Health

Associations between physical exercise and aging anxiety among older adults: a serial statistical mediation analysis involving self-efficacy and health anxiety

Wenmin Yu, Guoxi Ye

Background With the acceleration of global population aging, mental health issues among older adults have become increasingly prominent. Aging anxiety, defined as apprehension regarding the aging process and associated physiological, psychological, and social role losses, significantly impacts the quality of life and health of the older adults. Physical exercise has been shown to be associated with better physical and mental health of older adults, yet the theoretical psychological mechanisms underlying their assoc …

26.08.2026journal-article

Multimedia Systems

Augmented reality for remote care: a co-creation approach to supporting older adults and healthcare professionals

Achilleas Achilleos, Elena Kyprianou, Sotiria Moza, Joanna Starosta-Sztuczka, Karol Pecyna, Csaba Kostyal, Gyula Vad

Abstract Augmented Reality (AR) can enhance remote audio/video communication by enabling healthcare professionals to provide clear, intuitive instructions for older adults. AR solutions have proven effective in sectors like surgery and technical maintenance. Nevertheless, their use in the care of older adults remains limited. This paper presents an AR-enhanced audio/video communication service designed and developed by following an iterative, user-centered co-creation approach involving older adults, caregivers, an …

26.08.2026journal-article

Molecules

In Vitro Anti-Aging Properties of a Cetraria islandica Extract: Interest for Skin Care Cosmetics

Anthony Groso, Paul Jabet, Yang Fan, Wang Hua, Hu Yawen, Guo Miao, Richard Daniellou, Guillaume Collet

Skin aging is a major consideration regarding cosmetic skin care. The cosmetic field is seeking new active ingredients able to slow down the appearance of signs of age. Some lichens and more specifically the genus Cetraria s. str. presents an interest as a source of active molecules because it is already being used in traditional and modern medicines. To better evaluate the potential of C. islandica as anti-aging skin care, we investigated some key aspects to protect skin from external aggression and to avoid skin …

26.08.2026journal-article

JMIR Formative Research

Health Care Professionals’ Estimation of Home Spirometry Use Among People With Cystic Fibrosis: Cross-Sectional Study

Aqeem Azam, Andrew M Jones, Rowland J Bright-Thomas, Alex Horsley, Peter J Barry

Abstract Background Home spirometry has been widely adopted in the delivery of cystic fibrosis (CF) care. While existing literature largely supports its feasibility and positive outcomes, behavior around home disease monitoring remains poorly understood. Inaccurate assumptions about home spirometry behavior may affect resource prioritization and influence clinical decisions and follow-up. Objective This study aimed to evaluate health care professionals’ (HCPs’) ability to estimate home spirometry use among people w …

26.08.2026journal-article

Molecules

Multi-Level Evaluation of Antioxidant Activity, Aging-Related Physiological Functions, and Longevity Effects of Nelumbo nucifera Gaertn. Embryo Extract, Pleuropterus multiflorus (Thunb.) Turcz. ex Nakai Stilbene Glycoside, and Pterostilbene

Kuo-Ching Jan, Jung-Chun Tai, Xiao-Zhong Liu, Yu-Mei Li, Mohsen Gavahian

Despite known antioxidant activity, the effects of plant-derived compounds on aging-related physiological functions and mechanisms remain unclear, which necessitates investigation at cellular and organismal levels. To examine whether these compounds can mitigate age-related physiological decline, Nelumbo nucifera Gaertn. (sacred lotus) embryo extract–water-soluble fraction (NEW), stilbene glycoside from Pleuropterus multiflorus (Thunb.) Turcz. ex Nakai (PM-SG), and pterostilbene were investigated through chemical p …

26.08.2026journal-article

Journal of Holistic Nursing

Holistic Nursing Care for People Experiencing Diabetes Burnout: A Theoretical Reflection Using the Tidal Model

Marcelino Maia Bessa, Rodrigo Jácob Moreira de Freitas, Maria Célia de Freitas, Vanessa de Araujo Lima Freire, Lourival Veras de Oliveira, Sherida Karanini Paz de Oliveira

Diabetes burnout is an emerging psychosocial phenomenon characterized by emotional, physical, and mental exhaustion associated with the continuous demands of diabetes management, adversely affecting self-care and wellbeing. This study aimed to develop a theoretical reflection on how the principles of the Tidal Model, interpreted through the lens of holistic nursing, may inform nursing care for individuals experiencing diabetes burnout. This theoretical reflection was based on an analytical and interpretive approach …

26.08.2026journal-article

Artefactum - revista de estudos interdisciplinares

EFFECTS OF STRENGTH TRAINING AND WALKING ON FLEXIBILITY, HAND GRIP STRENGTH, AND UPPER AND LOWER LIMB STRENGTH IN ADULTS AND OLDER ADULTS

Paulo Henrique de Sousa Gomes, Hanna Nayane Souza Soares, Maria de Lourdes Machado de Resende Neta, Allyne Kelly Carvalho Farias, Ícaro Soares de Carvalho Pinheiro, Letícia Rebeca Soares Melo, Francisca Islândia Cardoso da Silva, Patrícia Uchôa Leitão Rebouças

O processo de envelhecimento é inerente a todos, fazendo-se necessário pesquisas e discussões para entender os riscos e as limitações que este processo traz a adultos de meia idade e a população idosa. Diante disso, o objetivo desse estudo foi comparar o efeito do treinamento de força e da caminhada na flexibilidade, força de preensão palmar e força de membros superiores e inferiores entre adultos e idosos. Foi realizada uma pesquisa com 25 participantes, divididos em dois grupos, praticantes de treinamento de forç …

26.08.2026journal-article

The International Journal of Aging and Human Development

Building Student Skills and Belonging as Geroscience and Gerojustice Researchers Through a Longevity and Aging Research Education Program: A Qualitative Analysis

Ambria Crusan, Shavonnye Rath, Paula C. Furey, Joshua D. Guggenheimer, Marcella J. Myers, Katherine A. Campbell

Addressing cumulative health disparities across the lifespan requires a scientific workforce trained at the intersection of geroscience and gerojustice. By integrating holistic academic and social support, an interdisciplinary Longevity and Aging minor, and scaffolded intramural and extramural research mentorship, the Katies for Aging Research and Equity (KARE) Program at St. Catherine University positions students to succeed as future aging researchers. To evaluate student growth, focus group transcripts, written …

26.08.2026journal-article

Geriatrics & Gerontology International

Withholding Oral Anticoagulation at Discharge and Post‐Discharge Stroke and Bleeding Vulnerability in a Predominantly Older Cohort Hospitalized With Acute Heart Failure and Atrial Fibrillation

Jumpei Yamamoto, Keijiro Nakamura, Hiromasa Hayama, Yoshinari Enomoto, Masaya Yamamoto, Hidehiko Hara, Hisao Hara, Yukio Hiroi

ABSTRACT Aim In older adults hospitalized with acute heart failure and atrial fibrillation, bleeding concern often drives withholding of oral anticoagulation at discharge. Whether withholding marks a genuinely lower bleeding‐risk phenotype or residual clinical vulnerability is uncertain. We examined its association with post‐discharge ischemic stroke, major bleeding, and death in a predominantly older cohort. Methods We analyzed a registry of patients hospitalized with acute heart failure and atrial fibrillation. I …

26.08.2026journal-article

Life

Arterial Stiffness and Anti-NR2/GluN2 Autoantibodies to N-Methyl-D-Aspartate Receptors as Markers of Vascular Aging and Cognitive Impairment in Arterial Hypertension

Tatiana Safronova, Sofia Mukhanova, Anna Bragina, Aida Tarzimanova, Alexander Ivannikov, Tatiana Vargina, Anna Pokrovskaya, Julia Rodionova, Natalia Druzhinina, Lyubov Vasilyeva, Alexander Cherepanov, Nikolay Dorokhov, Natalia Gureva, Natalia A. Dragomiretskaya, Irakli Zh. Loriya, Valery Podzolkov

Background: Arterial hypertension (HTN) is associated with accelerated vascular aging, cerebral microvascular injury, and cognitive decline. Anti-NR2/GluN2 (NR2) antibodies may be related to N-methyl-D-aspartate receptor (NMDAR)-mediated neuronal-ischemic injury, although their clinical significance in HTN requires further clarification. Objective: The aim of this study was to evaluate cross-sectional associations between arterial stiffness assessed by the cardio-ankle vascular index (CAVI), serum NR2 antibody leve …

26.08.2026journal-article

Journal of Exercise Rehabilitation

Influence of sarcopenia on functional independence and depression in older adults: a cross-sectional study

Tae-Hyun Yoon, Yong-Seok Jee

Differences in physical function, encompassing activities of daily living (ADL) and instrumental activities of daily living (IADL), and depression were evaluated across degrees of sarcopenic severity in older adults. A total of 236 participants (78.72±6.92 years), comprising 101 men and 135 women, were classified into four groups: no sarcopenia (23.7%), possible sarcopenia (26.3%), sarcopenia (28.0%), and severe sarcope-nia (22.0%). Sarcopenic measures included calf girth, grip strength, 5-time chair stand test, an …

26.08.2026journal-article

BMC Psychiatry

A holistic approach to support people with mental illness and mental ill-health: a mixed-methods study of clubhouse participation and its perceived impact

Hanna Isabel Løyland, Ingrid Engebretsen, Marianne Lefsaker Johansson, Anne Hellum, Erik Magnus Sæther, June Ullevoldsæter Lystad, Kine Pedersen

Abstract Background Mental illness poses health and societal challenges. The Clubhouse model offers a community-based approach aimed at promoting social inclusion and enhancing quality of life for individuals experiencing mental illness. We aimed to identify the characteristics of individuals engaging with Clubhouses in Norway (referred to as members), examine their patterns of attendance and engagement, and evaluate their experiences with participation in Clubhouse activities. Methods We employed a mixed-methods d …

26.08.2026journal-article

Comunicación y Sociedad

Jóvenes y desafección política en contextos de polarización. El caso de la juventud universitaria en el proceso electoral de 2024 en México

Maricela Portillo Sánchez

El objetivo de este artículo es analizar la desafección política de jóvenes universitarios en el contexto electoral de 2024 en México, comparando los datos con Kriger y Toribio (2023). Los resultados apuntan a una confianza relativa sobre el voto y la política, así como a la centralidad de la información que consumen a través de las redes sociales y los medios de comunicación. Las conclusiones indican que desafección no implica desinterés por parte de la juventud, sino hartazgo de una forma de ejercer la política p …

26.08.2026journal-article

Research on Aging

Connected and Eager to Learn: Digital Skills, Challenges, and Unmet Needs of Older Adults in Long-Term Care Facilities

Annalise Baines, Eszter Hargittai, Gerta Lokaj

This study explores the digital skills and challenges of older adults living in long-term care settings. We conducted 14 focus group interviews with 59 residents in Switzerland, with an average age of 80, to identify the competencies they possess and the skills they lack. Participants described using digital tools to stay connected and maintain autonomy. However, they also reported barriers such as cognitive limitations, rapid technological changes, and difficulty managing digital information. Despite these challen …

26.08.2026journal-article

AIDS

The additive value of coronary calcium in identifying cardiovascular risk in ageing people with HIV

Maithili Varadarajan, Ruth Byrne, Abethale Al-Hussaini, Brian Halliday, Edward Nicol, Mark Nelson, Alan Winston, Marta Boffito

In people without HIV, raised coronary artery calcium scores (CACS) are linked to increased cardiovascular risk. HIV is associated with elevated CACS, but risk factors beyond smoking and diabetes are not well established. Data on 779 individuals with HIV who underwent a CACS scans (median age 55) were collected. CACS better predicted adverse outcomes (e.g. major adverse cardiovascular events (MACE), death, heart failure) than Q-risk scores. Advanced imaging research may improve major cardiovascular risk prediction …

26.08.2026journal-article

Pakistan Journal of Gastroenterology

Urine Like Diarrhea in Older Children: Two Case Reports

Md Benzamin, ASM Bazlul karim

Background: Urine like diarrhea’ is seen in Congenital Chloride Losing Diarrhea (CCLD), which usually starts during neonatal period. But without prior history of CCLD, it is rare in older children, and no reported case till now. Case presentation: Two Bangladeshi children, presented with ‘urine-like diarrhea’ for more than 14 days, without any previous history or suggestive findings. All investigations were negative for any etiology except fecal impaction seen on x-ray abdomen. After disimpaction, both child were d …

26.08.2026journal-article

Frontiers in Endocrinology

Atherogenic index of plasma as a simple marker for NAFLD risk stratification in community-dwelling older adults: a cross-sectional study with incremental predictive value assessment

Mengyuan Xiao, Chengwen Xiao, Jiayu Zhang, Yuchen Ji, Jiayan Zhuang, Yingqi Chen, Zhihong Yuan, Siying Chen

The atherogenic index of plasma (AIP), calculated as log 10 (triglycerides/HDL-C), reflects atherogenic dyslipidemia and is associated with insulin resistance. Its continuous dose-response relationship and incremental predictive value for non-alcoholic fatty liver disease (NAFLD) beyond traditional risk factors remain undefined in community-dwelling older adults—a population with a high metabolic comorbidity burden where low-cost, integrated risk markers are urgently needed. Methods From 5,783 residents aged ≥65 ye …

26.08.2026journal-article

Diseases

Oral Structural and Functional Impairment in Relation to Depressive Outcomes in Older Adults: A Systematic Review and Meta-Analysis of Observational Studies

Lavinia-Alexandra Moroianu, Laurentiu Dragus, Stefan Rosca, Magdalena Rusu Negraia, Valeriu Ardeleanu, Rares Nicolae Vadana, Ionelia State, Georgel Mihu, Madalina Nicoleta Matei, Simona Dana Mitincu Caramfil

Background/Objectives: Oral structural and functional impairment and depressive outcomes frequently coexist in older adults, but the strength and interpretation of their association remain uncertain. This systematic review and meta-analysis evaluated whether poorer oral status or function is associated with depressive outcomes in older populations. Methods: Six databases were searched for observational studies published from 1 January 2016 to 5 January 2026, with an update on 19 April 2026. Eligible studies examine …

26.08.2026journal-article

Frontiers in Sports and Active Living

Can aerobic exercise really improve factors related to decision-making capacity in aging? What has been measured, what has been assumed, and what needs to change

Jonathan A. Cortés Silva, Christina A. Davis, Diego Lievano Parra, Valeria V. González

As populations age globally, cognitive decline has become one of the most pressing health challenges of our century. Early cognitive decline usually manifests as problems related to decision-making processes. In this context, aerobic exercise has emerged as a promising strategy for preserving and improving brain health. However, a critical question remains underexplored: whether improvements in executive function (EF) tasks truly reflect enhanced decision-making capacity, or whether they index more circumscribed ch …

26.08.2026journal-article

Psikoloji Çalışmaları / Studies in Psychology

Psychological Symptoms in Caregivers of Individuals Diagnosed with Dementia in Turkey: A Conservation of Resources Perspective

Elçin Yorulmaz, Gülay Dirik, Simge Balaban

Dementia is a disorder that is expected to increase in prevalence over the years and affects the daily lives of individuals. Because of its cognitive, emotional, and behavioral effects, dementia can impact a person's daily life and create a need for care. Since providing care involves many struggles, caregivers may experience numerous psychological symptoms. The purpose of the current study was to investigate the factors correlated with psychological symptoms experienced by caregivers of individuals diagnosed with …

26.08.2026journal-article

Frontiers in Immunology

Effect of blueberry consumption on regulatory lymphocyte phenotypes and NK cell functional activity in middle-aged and older adults with overweight or obesity: a randomized controlled trial

Abril I. Sánchez-Rosales, Sujatha Rajaram, Nadia Nemeh-Saad, Rawiwan Sirirat, Jacqueline Coats, Alan Cupino, Juli J. Unternaehrer, Joan Sabaté

Background Age-related changes in immune regulation and innate immune responses may be influenced by chronic low-grade inflammation associated with adiposity. Blueberries, rich in anthocyanins, may modulate inflammatory responses through effects on oxidative stress and phenolic metabolites; however, evidence from randomized controlled trials (RCTs) remains limited. We evaluated whether daily blueberry consumption modifies select cellular immune markers and inflammatory biomarkers in adults with overweight or obesit …

26.08.2026journal-article

Aging Cell

Associations Between Accelerometer‐Assessed Sleep Patterns, Proteomic Signatures, and Hallmarks of Aging in Adulthood

Ruiyi Liu, Jingsong Luo, Yangchang Zhang, Furong Wang, Jing Xu, Wangnan Cao, Shengzhi Sun

ABSTRACT The associations between objectively measured sleep patterns, the hallmarks of aging, and their shared proteomic signatures remain poorly understood. In this study, we utilized wrist‐worn accelerometer data, plasma proteomic profiles, and health records from the UK Biobank to examine the associations between six defined sleep patterns and nine established hallmarks of aging. We further identified proteins jointly associated with both sleep patterns and aging hallmarks. Longer total sleep duration, greater …