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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
30.08.2026journal-article

Pharmaceutics

Recent Advances in Non-Viral Vectors for Gene Therapy and Gene Delivery: From Lipid Nanoparticles to Engineered Extracellular Vesicles

Yongfeng Yang, Tingting Song, Kaili Huang, Hong Huang, Maoyuan Zhao, Yi Li

Gene therapy and genome editing increasingly depend on the safe, effective, and cell-selective delivery of nucleic acids and protein–nucleic acid complexes. Although viral vectors remain important for applications requiring durable gene expression, non-viral vectors offer advantages in cargo capacity, modularity, transient expression, potential repeat dosing, and avoidance of vector–genome integration. Lipid nanoparticles (LNPs), polymeric nanoparticles, inorganic nanomaterials, extracellular vesicles (EVs), and bi …

30.08.2026journal-article

Journal of Holistic Nursing

Patterns and Predictive Factors of Health-Related Quality of Life Among Community-Dwelling Patients With Hypertension: A Cross-Sectional Study From Thailand

Suthasinee Srinoon, Jeeraporn Kummabutr, Pantip Sangprasert, Siriluck Kaewsriwong, Korawan Keaittipattanachai

Purpose To describe the patterns of health-related quality of life (HRQoL) across four WHOQOL-BREF domains and to identify independent predictive factors—including cognitive health mindfulness—among community-dwelling adults with hypertension in an urbanized area of Thailand. Design Descriptive cross-sectional study. Methods Three hundred and thirty adults (≥35 years) with physician-confirmed hypertension were recruited by multi-stage stratified random sampling from 11 sub-district health promoting hospitals. Measu …

30.08.2026journal-article

Physical Rehabilitation and Recreational Health Technologies

Effects of Yoga-Based Intervention with Bhramari Pranayama and Chakra Meditation on Sympatho-Vagal Balance in Perimenopausal Women: A Randomized Controlled Trial

Jayachitra Subramanian, Subbulakshmi Velusamy, Ethiraj Balaji, Nirmal Michael Salvi, Erianti

Purpose. Perimenopause is associated with progressive altered autonomic regulation manifesting as sympathetic hyperactivation and impaired parasympathetic modulation, increasing cardiovascular and psychological vulnerability. Heart rate variability (HRV) provides a validated, non-invasive index of cardiac autonomic regulation. Yoga-based interventions incorporating controlled breathing and meditation may favorably modulate sympatho-vagal balance, yet robust randomized controlled trial (RCT) evidence in perimenopaus …

30.08.2026journal-article

Academic Journal of Management and Social Sciences

A Study on Optimising Family Doctors’ Health Management Services for Chronic Diseases in the Elderly within the Community-Based Home Care Model

Mingxuan Hui

Against the backdrop of community-based home care for the elderly, family doctors are key service providers in the health management of chronic diseases among the elderly. Taking the Pujin Community Health Service Centre in Shanghai as a case study, this paper adopts a combination of literature review, case analysis and interviews to examine the current status and challenges of family doctors’ involvement in the management of chronic diseases among the elderly. The study found that whilst family doctors are already …

30.08.2026journal-article

Frontiers on Healthcare Research

Research Trends and Perspectives on Psychiatric Nursing: A Decade of Progress and Challenges

Nursing Program, Universitas Syedza Saintika, Jl. Prof. Dr. Hamka No. 228, Padang, West Sumatra, Indonesia, 25132, Veolina Irman Veolina, Helena Patricia Helena, Dwi Christina Rahayuningrum Rahayuningrum Dwi Christina Rahayuningrum, Emira Apriyeni Emira

<p style="font-weight: 400;"><strong>Background: </strong>Psychiatric nursing continues to evolve in response to changing clinical, social, and professional demands, and the volume of research in this field has grown rapidly. This study aimed to analyse research trends and perspectives in psychiatric nursing over the last decade using bibliometric mapping and a thematic review.</p> <p style="font-weight: 400;"><strong>Methods: </strong>A bibliometric analysis was conducted using the Scopus database for publications …

30.08.2026journal-article

Clinical Physiology and Functional Imaging

Mueller manoeuvre increases the mitral‐to‐aortic velocity–time integral ratio, a mitral regurgitant index, in patients with dilated cardiomyopathy

Juha Virolainen, Markku Ventilä, Markku Kupari

Abstract A reduction of intrathoracic pressure during the Mueller manoeuvre (MM) has been shown to decrease left ventricular (LV) forward stroke volume in patients with systolic heart failure. To assess the underlying mechanisms, we analyzed MM‐induced changes in LV inflow and outflow dynamics in 13 healthy individuals (mean age 42 y, 8 men) and in 13 patients with dilated cardiomyopathy (DCM) (mean age 44 y, 8 men) having LV ejection fraction <40% without mitral regurgitation. The subjects performed MM with a targ …

30.08.2026journal-article

Journal of Cardiovascular Electrophysiology

Brugada Syndrome in the Pediatric Population: Diagnostic Challenges and Clinical Outcome—Results of the German Multicenter Study COGIA

Lea Lippert, Tobias Burkard, Franziska Markel, Volker Debus, Fridrike Stute, Anna Kamphues, Robert Dalla Pozza, Stefan Rupp, Maria B. Gonzalez y Gonzalez, Claudia Junge, Majed Kanaan, Kirstin Hoff, Anja Hanser, Sven Dittmann, Dominik Sebastian Westphal, Isabel Diebold, Sebastian Clauß, Stefanie Kessner, Marc‐Phillip Hitz, Kolja Becker, Stefan Kääb, Peter Ewert, Michael Hofbeck, Wolfgang Wällisch, Sven Dittrich, Anselm Uebing, Stephan Neumann, Jan‐Hendrik Nürnberg, Joachim Hebe, Rainer Kozlik‐Feldmann, Philipp Beerbaum, Gunter Kerst, Eric Schulze‐Bahr, Roman Gebauer, Gabriele Hessling, Cordula Maria Wolf

ABSTRACT Introduction Diagnosis and treatment of children and adolescents with suspected Brugada syndrome (BrS) is challenging. Aim of the study was to evaluate the applicability of current diagnostic criteria for pediatric patients with suspected BrS in the German multicenter study COGIA and to assess clinical outcome. Methods Data analysis of 76 pediatric patients from 12 German tertiary care centers. Primary outcome was defined by the occurrence of a major arrhythmic event (MAE), secondary outcome by symptoms, p …

30.08.2026journal-article

IECCMEXICO

Beyond Technical Success: Postoperative Systemic Deterioration and Timely Clinical Rescue in Minimally Invasive Abdominal Surgery

José Eduardo Vallejo Ramírez, Ana Carla Naranjo González, Angie Michelle Junco Aguaiza, Diego Clemente Moreno, David Eduardo Espinosa Ortiz, Pablo Eduardo Navarro López, Vicente Treviño Caballero, Justin Santiago Palacios Moreira, Aldo Bolivar Zavala Segovia

Minimally invasive abdominal surgery reduces surgical trauma and facilitates postoperative recovery; however, it does not eliminate the risk of systemic complications or progression to organ dysfunction. This study evaluated the frequency, early manifestations, severity, and multidisciplinary management of systemic complications following laparoscopic and robot-assisted abdominal procedures. A prospective observational cohort design was used, including 263 adult patients with follow-up from the immediate postoperat …

30.08.2026journal-article

Nursing Open

Nurse‐Led Patient‐Reported Outcome Assessment of Symptom Burden and Quality of Life in Myeloproliferative Neoplasms: An Observational Study

Daniela Berardinelli, Carmen Fava, Valentina Bonuomo, Selene Grano, Federica Sinisi, Inga Ventimiglia, Graziella Costamagna, Paola Di Giulio, Sara Campagna, Andrea Ricotti, Valerio Dimonte

ABSTRACT Aim To investigate the symptom burden associated with MPNs and its impact on patients' psychophysical well‐being and quality of life through a structured PROM‐based nurse‐led visit. Design Observational study. Methods We included MPN patients followed at the haematology outpatient clinic of a large university‐affiliated hospital in Italy. Data were collected from September 2024 to March 2025 on 102 patients who underwent a structured PROM‐based nurse‐led visit supported by a dedicated symptom diary. Result …

30.08.2026journal-article

Anatolian Journal of Health Research

The relationship between infertility stress, coping, and quality of life among women undergoing infertility treatment

Büşra Çark, Seyhan Çankaya, Ümmügülsüm Esenkaya

Aim: This study aimed to examine the relationships between infertility-related stress, coping strategies, and quality of life among women undergoing infertility treatment. Methods: This descriptive, cross-sectional study was conducted between April-November 2025 with 200 women attending an infertility outpatient clinic at a city hospital in Central Anatolia, Türkiye. Data were collected using a Personal Information Form, the COMPI Fertility Problem Stress Scales, the COMPI Coping Strategy Scales, and the Fertility …

30.08.2026journal-article

Journal of Prevention and Health Promotion

Pastor-Led Technology-Delivered Mental Health Promotion Program for Improving Quality of Life Among Older Black Adults in the United States

Carolyn M. Tucker, Kirsten G. Klein, Kaylyn A. Garcia, Eloise M. Harrison, Kelly L. Folsom, Guillermo M. Wippold

Older Black adults experience high rates of adverse health concerns that contribute to high morbidity and premature mortality. To address these health disparities, it is recommended that health promotion interventions are culturally tailored (e.g., leveraging faith and spirituality) to the unique needs of older Black adults. Such interventions must recognize that older Black adults often report experiencing barriers to engagement in interventions such as transportation and cost. The purpose of the present study was …

30.08.2026journal-article

Primary: Jurnal Pendidikan Guru Sekolah Dasar

A Systematic analysis of teachers' strategies for promoting resilience and mental health among elementary students following bullying

Ningrum Perwitasari, Annisa Adelia, Claresta Cleo Sagita, Shifa Putri Azzahra

The phenomenon of bullying or violence often occurs anywhere, whether at home, in the workplace, or even in educational environments. A safe and peaceful life is a desire longed for by everyone; therefore, with a balanced life, harmonious relationships can be built. However, the reality is often different for those who become victims of bullying, resulting in serious negative impacts on quality of life and mental health. The method used in this study is a systematic literature review (SLR). Regarding this study, te …

30.08.2026journal-article

Ukrainian Heart Journal

Ізольована дисекція верхньої брижової артерії: ендоваскулярне лікування. Клінічний випадок

S. M. Furkalo, Yu. H. Vahis, A. O. Danylets

The aim – to describe a case of elective endovascular treatment of asymptomatic spontaneous isolated dissection of the superior mesenteric artery with a self-expanding covered stent via right transbrachial access and to justify the indication for intervention based on morphological risk criteria.Materials and methods. The follow-up of a 67-year-old man with coronary artery disease, compensated type 2 diabetes mellitus, arterial hypertension, dyslipidaemia and previous left total hip arthroplasty is presented. The d …

30.08.2026journal-article

KOMUNITA: Jurnal Pengabdian dan Pemberdayaan Masyarakat

Healthy Tooth Generation: Interactive Oral Health Education Using Digital Media for Students of SMA Bina Jaya Kertapati Palembang

Mellani Cindera Negara, Sulistiawati Sulistiawati, Trisnawaty K, Danica Anastasia

Oral health problems remain a major public health issue in Indonesia, particularly among adolescents, who often have limited knowledge and inappropriate toothbrushing practices. SMA Bina Jaya Kertapati Palembang is a senior high school located in a densely populated urban area, with most students coming from lower-middle socioeconomic backgrounds and having limited access to oral health education and services. This community service program aimed to improve students’ literacy and preventive behavior related to dent …

30.08.2026journal-article

International Journal of Computer Information Systems and Industrial Management Applications

Single- and Extended-Authority CP-ABE for E-Healthcare Security in Cloud-IoT

Gurupriya K G, Dr. A. S Aneeshkumar

The integration of Internet of Things (IoT) devices into clinical environments has generated volumes of electronic health records (EHRs) that exceed the management capacity of conventional access control mechanisms when these records are offloaded to cloud platforms. Protecting health records with fine-grained, cryptographically enforced access control while supporting dynamic credential revocation at cloud scale has remained an open problem in practice. Existing Ciphertext-Policy Attribute-Based Encryption (CP-ABE …

30.08.2026journal-article

International Journal of Human and Health Sciences (IJHHS)

Out-of-Field Doses in Breast and Pelvic Photon Radiotherapy

Bassey Eyo Archibong, Samuel Okon Inyang, Cynthia Onyinyechukwu Igba, Isaac Bassey Ekong, Nneoyi Onen Egbe, Bede Madu, Victor Ekpo, Mary Ann Ekpo, Happiness David

A retrospective dosimetric analysis was conducted using treatment planning systems from two radiotherapy centers in Cross River State, Nigeria, equipped with advanced linear accelerators delivering Intensity-Modulated Radiation Therapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT), to investigate the levels of out-of-field radiation doses in modern photon radiotherapy and strategies to minimize exposure to normal tissues. A total of 88 patient treatment plans (41 for pelvic cancer and 47 for breast cancer) wer …

30.08.2026journal-article

Borneo Nursing Journal (BNJ)

Efektifitas Konsumsi Buah Naga Merah (Hylocereus Polyrhizus) dan Tablet Fe terhadap Peningkatan Kadar Hemoglobin pada Ibu Hamil di Wilayah Kerja Puskesmas Paringin

Ismawati Ismawati, Mahfuzhah Deswita Puteri, Shelly Rodliah Rosyad, Rr. Sri Nuriaty Masdiputri

Anemia merupakan kondisi defisiensi eritrosit dan/atau hemoglobin di bawah nilai normal yang menginduksi gangguan transpor oksigen sistemik. Pada kehamilan, anemia meningkatkan risiko komplikasi berupa distosia, persalinan prematur, BBLR, serta berbagai dampak lainnya. Data studi pendahuluan menunjukkan prevalensi anemia maternal di Kabupaten Balangan tahun 2025 sebanyak 280 orang. Di wilayah kerja Puskesmas Paringin, proporsi tahunan mencapai 31,6% (64 orang). Periode Januari–Februari 2026 mencatat peningkatan men …

30.08.2026journal-article

Research Output Journal of Public Health and Medicine

Burnout and Compassion Fatigue Among Nurses: Causes, Consequences and Strategies for Resilience and Self Care

Chioma Ibe, Solomon Justina Adanma Nwagwu, Kaunda Julia Ibebuike, Chinelo Clare Vincent, Anthonia Chinwendu Emesowum, Onyekwuo Festa Chinonye, Emmanuel Ifeanyi Obeagu

Burnout and compassion fatigue have become increasingly prevalent among nurses due to the demanding nature of the nursing profession and the continuous exposure to physical, emotional, and psychological stressors. These conditions not only affect the well-being of nurses but also compromise the quality and safety of patient care. This seminar explores burnout and compassion fatigue among nurses by examining their causes, consequences, and strategies for resilience and self-care. The major causes discussed include e …

30.08.2026journal-article

Journal of Gazi University Health Sciences Institute

Management of Pain, Mobilization, and Pressure Injuries in Complex Revision Arthroplasty: A Multidisciplinary Case Report

Sümeyye Kuzucu, Mehmet Musa Emir, Sevil Güler, Durmus Ali Ocguder

Complex revision arthroplasties are indicated particularly in cases of severe bone loss, aseptic loosening, periprosthetic infection, and recurrent instability. Revision total hip arthroplasty is associated with higher complication rates and greater functional limitations than primary surgery. This study aimed to evaluate the effects of a multidisciplinary approach on pain, mobilization, and pressure injury following revision hip arthroplasty in a high-risk patient. The case involved a 75-year-old patient with a hi …

30.08.2026journal-article

European Heart Journal

Safety of withdrawal of pharmacological treatment after recovery from HER2 therapy-related cardiac dysfunction: the HER-SAFE trial

B Dowsing, H-M Dehbi, M S Andres, R Chung, A Oashou, J M Wilson, I Hussein, B Meredith, I Pierce, S Ahmed, J Pedra, O Worn, M Howe, S Assadullah, P Schmid, R Roylance, T Crake, M Westwood, A K Ghosh, D Auger, C M Plymen, J Baksi, M S Nazir, J C Moon, D Chen, A R Lyon, J M Walker, C H Manisty

Abstract Background Heart failure therapy (HFT) is routinely continued in breast cancer survivors after recovery from anti-HER2 cancer therapy-related cardiac dysfunction (CTRCD), despite limited evidence. HER-SAFE is the first randomised trial to assess HFT withdrawal in this population. Methods In this open-label, multicentre, randomised controlled trial, breast cancer survivors with recovered anti-HER2 CTRCD (asymptomatic, left ventricular ejection fraction [LVEF] ≥50%, normalised biomarkers) were randomised to …

30.08.2026journal-article

Frontiers on Healthcare Research

The Role of Cell Block in Diagnosing Metastatic Adenocarcinoma in Pleural Fluid: A Case Series

Department of Anatomical Pathology, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia, Salsa Hanisa Anwar Salsa Hanisa, Anatomical Pathology Laboratory, Dr. H.A. Rotinsulu Pulmonary Hospital, Bandung, Indonesia, Desi Puspita Desi, Hermin Aminah Usman Hermin Aminah

<p style="font-weight: 400;"><strong>Background:</strong> Cytological examination of pleural fluid is an important, inexpensive, and simple test for detecting malignancy in patients with clinical pleural effusion who undergo thoracentesis. Adenocarcinoma is the most common tumor type. However, diagnosis using the conventional smear method can be challenging when the typical glandular-like growth patterns are not visible. Cell block preparation from pleural fluid samples preserves tissue architecture and tumor cell …

30.08.2026journal-article

MedComm

Artificial Intelligence Integration With Nanotechnology for Cancer Therapy

Shengbin Liu, Zhi Liu, Haixing Shi, Chengyi Wei, Ruijie Zhang, Xiangrong Song

ABSTRACT Cancer nanomedicine offers a versatile platform for improving therapeutic index, but its clinical translation remains limited by unpredictable in vivo behavior, heterogeneous biological contexts, and inefficient design paradigms. Artificial intelligence (AI) is emerging as an integrative framework that links data‐driven modeling with nanomedicine design, biological transport, and clinical decision‐making. In this review, we discuss AI‐guided strategies for material design, targeting, payload optimization, …

30.08.2026journal-article

World Medical & Health Policy

Two Decades of Research on Government Funded Health Insurance in India (2007–2025): A Bibliometric Analysis of PM‐JAY and Related Schemes

Sagar Pandey, Pushpender Yadav

ABSTRACT Government‐funded health insurance (GFHI) has become a central component of India's health financing strategy, generating substantial research across public health, health policy, and health systems. However, there is a need to comprehensively map the intellectual evolution of this field. This study conducted a bibliometric analysis using records of publications from Scopus and Web of Science core collection databases. After screening, deduplication, and application of predefined eligibility criteria, a to …

30.08.2026journal-article

Journal of Health Psychology

The relationship between benefit finding and fear of progression in patients with chronic heart failure: Mediating role of coping style and moderating role of hospitalization frequency

Meijia Gao, Jie Meng, Jianglin Fan, Yimiao Tian, Zhimin Feng, Shaoying Du

This cross-sectional study investigated the moderated mediating roles of coping style and hospitalization frequency in the benefit finding–fear of progression relationship among 332 heart failure patients. Findings suggested that resignation coping mediated the impact of benefit finding on fear of progression, implying that alleviating such resignation coping may improve patients’ fear of progression. Furthermore, hospitalization frequency emerged as a significant negative moderator of resignation coping’s mediatin …