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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
31.08.2026journal-article

Magna Scientia Advanced Research and Reviews

AI-Driven Privacy-Preserving Techniques in US Healthcare Cybersecurity: A Narrative Review

Isaiah Thompson Ocansey, Mary Magdalene Yeboah

The United States healthcare sector grapples with rising cybersecurity threats. Ransomware and data breaches expose millions of protected health information (PHI) records each year, while artificial intelligence (AI) has advanced analytics and supported clinical decisions and tools. AI amplifies both vulnerabilities and protections, but traditional safeguards often struggle or fail to support collaborative model development with stringent HIPAA and HITECH rules. Privacy-preserving machine learning (PPML) techniques …

31.08.2026journal-article

International Journal of Science and Research Archive

SODIUM-GLUCOSE COTRANSPORTER-2 INHIBITORS BEYOND DIABETES: AN EMERGING CARDIORENAL STRATEGY IN INTERNAL MEDICINE

Renata dos Santos Cunha, Anny Karollynny Batista de Oliveira Neves, Camila Chagas Moreira Alves, Igor Diniz Sato, Maria Eduarda Calil Alves

Sodium-glucose cotransporter-2 (SGLT2) inhibitors were initially developed as glucose-lowering agents for patients with type 2 diabetes mellitus. However, accumulating evidence has demonstrated substantial cardiovascular and renal benefits that extend beyond glycemic control and may occur independently of diabetes status. To review the current evidence regarding the use of SGLT2 inhibitors as a cardiorenal therapeutic strategy in patients with heart failure and chronic kidney disease, with particular emphasis on re …

31.08.2026journal-article

Osong Public Health and Research Perspectives

Association between ambient temperature and blood pressure in hypertensive adults in Bogor City, Indonesia: a 6-year longitudinal cohort study

Puti Sari Hidayangsih, Woro Riyadina, Ika Dharmayanti, Pandji Wibawa Dhewantara, Ning Sulistiyowati, Noor Edi Widya Sukoco, Yuda Turana

Objectives: Climate variability, particularly ambient air temperature, is an emerging environmental determinant of blood pressure (BP); however, evidence from tropical low- and middle-income countries (LMICs) remains limited. We examined associations between monthly average ambient temperature with systolic BP (SBP) and diastolic BP (DBP) among adults in Bogor City, Indonesia.Methods: This longitudinal cohort analysis used secondary data collected between 2011 and 2018 from 1,648 participants with repeated BP measu …

31.08.2026journal-article

Archiv Euromedica

COLLAGEN SUPPLEMENTATION AND TISSUE HEALTH IN MIDDLE-AGED AND OLDER ADULTS: A NARRATIVE REVIEW OF CLINICAL EVIDENCE

Aleksandra Maria Błoch, Natalia Rządzińska, Kornelia Julia Fimiarz, Aleksandra Olga Pakulska, Maria Anna Miller, Aleksandra Jolanta Kamińska, Aleksandra Katarzyna Kłosowicz

Background Collagen is the principal structural protein of connective tissues, including the skin, cartilage, tendons, bone, and blood vessels. Ageing is associated with changes in collagen synthesis, organisation, cross-linking, and degradation, which contribute to reduced tissue integrity and function. Collagen supplementation has therefore been investigated as a nutritional strategy to support tissue health in middle-aged and older adults. Aims This narrative review aimed to summarise current evidence on the phy …

31.08.2026journal-article

Journal of Education, Health and Sport

Emerging Biologic Strategies in Crohn’s Disease

Natalia Niderla, Jakub Rzeszutek, Adrian Kubicki, Natalia Rachwał, Karolina Obuchowska, Dominika Grzybowska, Michał Kurnik, Adrianna Jaślikowska, Kamil Idzik, Weronika Grzyb

Crohn’s disease is an inflammatory bowel disease, which substantially impairs patients’ quality of life. Despite ongoing advances, effective long-term management remains challenging in many cases. Conventional therapies are often associated with significant adverse effects and limited suitability for sustained use. This review provides an overview of the current landscape of novel biological therapeutics and their molecular targets. Several biologic therapies are already well established in clinical practice. Among …

31.08.2026journal-article

BMC Oral Health

Evaluation of thermocycling, color stability, surface roughness and hardness of nanocarbon HPP, BioHPP and PEEK used for fabrication of prosthetic restorations ( in vitro study)

Mohamed Z. Basiony, Rim A. Selima, Nermeen A. Rady, Sherif M. Abdel Hamid

Abstract Statement of problem The selection of appropriate dental materials plays a crucial role in the success of prosthetic restorations. With the limitations of metallic alloys, including their aesthetic shortcomings, weight, corrosion potential, and cost, there is growing interest in high-performance polymer alternatives. Purpose The objective of the present study was to evaluate color stability, surface roughness and Hardness of BioHPP, Nanocarbon HPP and PEEK used for fabrication of prosthetic restorations (A …

31.08.2026journal-article

Oil and Gas Business

IMPROVING THE OCCUPATIONAL HEALTH AND SAFETY TRAINING SYSTEM IN LUKOIL-WESTERN SIBERIA LLC

Yulia F. Yakovleva, Inna V. Ozden

This article proposes improvements to the occupational safety training system at LUKOIL-Western Siberia LLC for methanol handling. The relevance of the study is due to the high toxicity and fire hazard of methanol, as well as the ineffectiveness of traditional forms of personnel training. An analysis of the current employee training and knowledge monitoring system was conducted, identifying key shortcomings: the formal nature of training, insufficient practical focus, and limited use of modern training methods. Bas …

31.08.2026journal-article

IIARD INTERNATIONAL JOURNAL OF ECONOMICS AND BUSINESS MANAGEMENT

Relationship Between Gender Discrimination, Work-Life Balance and Mental Health: The Nigerian Female Educators’ Perspective

Ekene Ezinwa Nwankwo

This study examined relationship between gender discrimination, work-life balance and mental health: The Nigerian female educators’ perspective. Two specific purposes, two research questions and two hypotheses guided the study. Correlational design was adopted for the study. The population of the study comprised all the 10,009 female teachers in public secondary schools in Anambra State. The sample size was 1,001 female teachers drawn using proportionate stratified random sampling technique. Structured rating scale …

31.08.2026journal-article

Indian Journal of Aerospace Medicine

Perception of oral health and oral health-related quality of life among aviators in the armed forces: A cross-sectional study

Srihari Krishna Kaushik, Adil Farzand, Harikrishnan Venkatakrishnan

Objectives: Oral health significantly influences functional performance and psychological well-being. Military aviators operate under unique physiological and operational stresses where even minor dental issues can compromise in-flight performance and safety. As evidence regarding oral health-related quality of life (OHRQoL) among military aviators is scarce, this study aimed to assess the perception of oral health and OHRQoL using the Oral Health Impact Profile-14 (OHIP-14) and to evaluate its association with dem …

31.08.2026journal-article

Frontiers in Digital Health

How professional logics shape AI implementation in mental healthcare: a qualitative study of an LLM-enhanced chatbot

Silvia Rizzi, Stefano Fait, Mattia Franzin, Leonardo Sanna

Introduction Large language model (LLM)-enhanced chatbots are increasingly proposed as scalable tools for mental health support. However, their successful integration into healthcare depends not only on technical performance, but also on clinicians' acceptance of these technologies and their perceptions of the value these tools can bring to clinical practice. This study examined how psychotherapists and general practitioners (GPs) perceived the potential of the implementation of an LLM-enhanced psychoeducational ch …

31.08.2026journal-article

Journal of Community Health Provision

Mental Readiness Mother Primigravida Prevents Problems and Postpartum Mental Health Problems: Scoping Review

Alya Nursyifa Perwata, Endang Koni Suryaningsih, Cesa Septiana Pratiwi

In general, giving birth is one of the fun events, on the other hand there is the presence of new family members in women's lives not always happiness. It needs adjustments to women who experience pregnancy and childbirth. Emotional disorders can be experienced by women after giving birth such as postpartum blues, postpartum depression or postpartum psycholigical. Objective: To map the literature on increasing the mental readiness of primigravida mothers in preventing problems and postpartum mental health problems. …

31.08.2026journal-article

Clinical and Experimental Otorhinolaryngology

A Marked Decrease in Speech Intelligibility Is No Longer a Major Characteristic of Vestibular Schwannoma in the Current Era

Masafumi Ueno, Makoto Hosoya, Hirotaka So, Nobuyoshi Tsuzuki, Marie N Shimanuki, Takanori Nishiyama, Hiroyuki Ozawa, Naoki Oishi

Objectives. Speech intelligibility is reported to be markedly decreased in patients with vestibular schwannoma (VS); however, the relationship between speech intelligibility and hearing level remains poorly characterized.Methods. We created scatter plots of pure-tone audiometry (PTA) thresholds and speech discrimination scores for 473 patients with sporadic, unilateral VS. Simple regression analysis and Pearson correlation coefficients were calculated and compared with data from 173 patients with asymmetric cochlea …

31.08.2026journal-article

Frontiers in Bioengineering and Biotechnology

Mid-infrared microscopy for label-free digital staining: initial clinical assessment

L. Duraffourg, H. Borges, M. Fernandes, M. Beurrier-Bousquet, J. Baraillon, B. Taurel, J. Le Galudec, K. Vianey, C. Maisin, L. Samaison, F. Staroz, M. Dupoy

Infrared (IR) microscopy shows substantial potential for label-free tissue imaging in anatomic pathology, providing rich biochemical contrast. However, existing IR imaging technologies are constrained by slow acquisition speeds and limited spatial resolution. Here, we present a rapid, large-field bimodal imaging platform that integrates conventional brightfield microscopy with a lensless IR imaging scanner, enabling whole-slide IR image stack acquisition in minutes. Using a dedicated deep learning model, we impleme …

31.08.2026journal-article

Frontiers in Medicine

Assessment tools for patients with stroke-related sarcopenia: a scoping review

Yanran Liang, Linli Xie, Wanwan Qiao, Runfang Guo, Hejia Wan, Jie Jing

Background The assessment of stroke-related sarcopenia (SRS) is not easy due to the paralysis and functional limitations in mobility after stroke. There is a need to identify tools for the assessment of SRS that stroke patients can complete. Objectives: This review aimed to summarize the tools that can be used to assess SRS. Methods Databases were systematically searched from the time of construction to 28 June 2026 based on the Arkensey and O’Malley framework. The databases searched included PubMed, Cumulative Ind …

31.08.2026journal-article

Frontiers in Medicine

Long-term outcomes of early posterior scleral contraction for myopic macular retinoschisis in patients up to 30 years

Linyan Zheng, Jian Zhao, Caiyu Yu, Liang Dong, Anquan Xue, Shuangqian Zhu

Aim To evaluate the long-term anatomical and functional outcomes of early posterior scleral contraction (PSC) in patients up to 30 years with myopic macular retinoschisis (MRS). Methods This retrospective study included 21 patients (27 myopic eyes) with MRS, with or without macular detachment, who underwent PSC and had a postoperative follow-up exceeding 2 years ( n = 27). Eyes with MRS underwent PSC, an extraocular procedure involving the placement of a genipin-crosslinked allogeneic strip at the posterior pole to …

31.08.2026journal-article

World Nutrition Journal

The impact of nutritional therapy in malnourished patient with tongue squamous cell carcinoma undergoing chemoradiation

Debtia Rahmah, Diana Sunardi, Nurul Ratna Mutu Manikam

Background: Malnutrition affects 30%-50% of patients with head and neck carcinoma. It is associated with reduced survival, increased risk of complications, treatment interruption, and higher treatment-related toxicity.1,2 Objective: This case aim to discuss about nutritional therapy in tongue carcinoma patient with malnourished and cachexia undergoing chemoradiotherapy. Case: A 52-year-old man with squamous cell carcinoma of the tongue presented with clinically severe malnutrition and cachexia. Imaging revealed a s …

31.08.2026journal-article

Journal of Pharmaceutical Science and Clinical Pharmacy

Tinjauan Literatur: Potensi Aktivitas Flavonoid dalam Bunga Chamomile (Matricaria chamomilla L.)

Siti Nur Aisyah Tanjung, Cszahreyloren Vitamia

Bunga chamomile (Matricaria chamomilla L.) banyak dimanfaatkan sebagai bahan herbal karena kandungan senyawa flavonoid yang berpotensi memberikan efek farmakologis. Penelitian ini bertujuan untuk mengkaji kandungan flavonoid serta aktivitas farmakologis chamomile berdasarkan tinjauan literatur tahun 2020–2025. Metode yang digunakan berupa analisis deskriptif terhadap artikel ilmiah yang diperoleh dari Google Scholar, PubMed, dan ScienceDirect. Pengujian aktivitas farmakologis dalam berbagai penelitian dilakukan mel …

31.08.2026journal-article

Neuro-Oncology

The role for surgery in IDH-mutant grade 4 Astrocytomas: interactive effects of resection, patient characteristics, and outcome - report of the RANO resect group

Philipp Karschnia, Gilbert Youssef, Jacob S Young, Nico Teske, Maarten M J Wijnenga, Antonio Dono, Okizeva Rapi, Yae Won Park, Arthur Wagner, Tommaso Sciortino, Francesco Bruno, Levin Häni, Felix Ehret, Nicolas Neidert, Einar O Vik-Mo, Roland Goldbrunner, Juergen Beck, Andreas Raabe, Roberta Rudà, Lorenzo Bello, Bernhard Meyer, Sung Soo Ahn, Asgeir S Jakola, Yoshua Esquenazi, Martin van den Bent, Shawn Hervey-Jumper, Mitchel S Berger, Patrick Y Wen, Oliver Schnell, Joerg-Christian Tonn, RANO resect group, Stephanie T Juenger, Eduardo E Mendoza Mireles, Alfred Gramelt, Raymond Y Huang, Annette M Molinaro, Alexander A Aabedi, Susan M Chang, Thijs van der Vaart, Arnaud J P E Vincent

Lay Summary Surgery is the first step in treating patients with the rare brain tumor IDH-mutant grade 4 astrocytoma. In an international study of 266 patients, we examined how the amount of tumor remaining after surgery affects survival. Patients with less remaining contrast-enhancing tumor lived longer. Those who underwent ‘supramaximal’ surgery (tumor removal beyond the visible enhancing portion) had the most favorable outcomes. Loss of the CDKN2A/B gene was linked to worse survival regardless of the extent of su …

31.08.2026journal-article

Caucasian Medical Journal

Incremental Diagnostic Value of the Serum Pepsinogen Ratio for Non-Invasive Prediction of Histological Gastric Atrophy: An Internally Validated Clinical–Infectious Model

N.S. Kerimkulov, G.H. Babayeva

Background: Histological gastric atrophy represents a critical step in the cascade leading to intestinal-type gastric cancer. Although upper gastrointestinal endoscopy with systematic biopsy remains the reference standard for detecting atrophic changes, its invasiveness, cost and limited suitability for repeated population-level assessment highlight the need for reliable non-invasive biomarkers.The serum pepsinogen I-to-II ratio (PGR) reflects the functional integrity of gastric glands and may decrease following lo …

31.08.2026journal-article

Blood Cancer Discovery

Tumor CD19 Expression Determines Distinct Clinical Outcomes After CD19 CAR T-Cell Therapy in Large B-Cell Lymphoma

Magdalena Corona, Aaron Gillmor, Kimon V. Argyropoulos, Teng Fei, Maria Isabel Sotelo-Alva, Mohammad Alhomoud, Parastoo B. Dahi, Anthony F. Daniyan, Mark T.A. Donoghue, Sigrun Einarsdottir, Lorenzo Falchi, Qi Gao, Gregory Goldgof, Marina Gomez-Llobell, Erel Joffe, Richard J. Lin, Alejandro Luna de Abia, Efrat Luttwak, M. Lia. Palomba, Jae H. Park, Sandeep S. Raj, Kai Rejeski, Alfredo Rivas-Delgado, Gilles Salles, Jaime Sanz, Michael Scordo, Gunjan L. Shah, Sulov Chalise, Manik Uppal, Anna Gurevich-Shapiro, Menglei Zhu, Miguel-Angel Perales, Allison L. Richards, Mikhail Roshal, Roni Shouval

Abstract It remains uncertain whether lower CD19 expression is clinically relevant for outcomes of CD19 CAR-T therapy of large B-cell lymphoma (LBCL). We conducted an integrative analysis of tumor CD19 levels with centralized quantitative assessment by flow cytometry (FC), immunohistochemistry and RNA-sequencing in a LBCL cohort (n=301). Pre-treatment CD19 by FC correlated with 1-year progression-free survival following axicabtagene ciloleucel or lisocabtagene maraleucel (16%, 53% and 64% for CD19low, CD19intermedi …

31.08.2026journal-article

Gazi Sağlık Bilimleri Dergisi

AGING BEYOND NUMBERS: THE ASSOCIATION BETWEEN POPULATION AGING AND COST-RELATED HEALTHCARE ACCESS IN OECD COUNTRIES

Zeliha Köse, Kenan Kıbıcı

Background: This study examines the association between population aging and cost-related healthcare access across OECD countries. Methods: An unbalanced panel dataset comprising 102 country-year observations from 15 OECD countries over the period 2000–2023 was analyzed. Fixed-effects and random-effects models with standard errors clustered at the country level were estimated. Based on the Hausman test, the random-effects model was retained as the preferred specification. Results: In the preferred random-effects mo …

31.08.2026journal-article

Clinical Practice and Cases in Emergency Medicine

Soft Palate Perforation with Endotracheal Tube During Video Laryngoscopy

Samuel J. Thomas, David I. Zimmer, Jack H. Langford, Toby J. Brenner, Kate M. Kelly, Donald F. Zimmer

Case presentation: A 57-year-old man with a history of obesity-hypoventilation syndrome, diabetes mellitus, and chronic renal insufficiency was intubated with an 8.0-mm endotracheal tube under video laryngoscopy in the emergency department due to respiratory failure. After successful intubation, bloody secretions were noted in the patient’s mouth. Subsequent examination revealed that the endotracheal tube had caused a through-and-through perforation at the junction of the soft palate and the anterior tonsillar pill …

31.08.2026journal-article

SJ Pediatrics and Child Health Africa

<b>Growth patterns and associated factors among children receiving long-term inhaled corticosteroid therapy for asthma. A hospital-based prospective observational cohort study.</b>

Ankit Kumar Gupta, Alok Singh, Thakur Shivani

BackgroundInhaled corticosteroids (ICS) are central to persistent asthma management in children, but prolonged exposure may affect linear growth, particularly at higher doses or with repeated systemic corticosteroid use. ObjectivesTo describe growth patterns and identify factors associated with reduced height velocity among children receiving long-term ICS therapy for asthma. MethodsThis prospective observational cohort study included 100 children aged 5–14 years at RSDKS Government Medical College, Ambikapur, Chha …