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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
31.08.2026journal-article

Journal of Evaluation in Clinical Practice

Clinical Decision‐Making and Guideline Alignment Among Brazilian Physical Therapists: Evidence From Standardized Carpal Tunnel Syndrome Vignettes

Luciane Fernanda Rodrigues Martinho Fernandes, Brenda Thaís Alves Cardoso, Darlisson Bueno Paranhos, Vítor Hugo Mendes Castro, Amanda Avelar de Resende, Paula Regina Mendes da Silva Serrão

ABSTRACT Background Clinical practice guidelines (CPGs) are intended to support evidence‐based clinical decision‐making. However, the extent to which physical therapists' clinical decisions align with guideline recommendations remains uncertain, particularly in Brazil. Objective To evaluate the alignment of Brazilian physical therapists' clinical decisions with recommendations from CTS clinical practice guidelines and to examine whether general evidence‐based practice (EBP) knowledge, self‐reported guideline use, a …

31.08.2026journal-article

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine

Can LLMs reliably perform epidemiological extraction in elite football?

Julio López-Álvarez, Adrián Feria Madueño

Anterior cruciate ligament (ACL) injuries remain a critical burden in professional football, resulting in prolonged absence and high economic costs. While physical demands have increased, traditional epidemiological surveillance relies on manual data extraction, which is resource-intensive and subjective. Large Language Models (LLMs) offer a potential solution for automated screening, but their reliability in sports medicine remains largely unexplored. This study aimed to: (1) update the epidemiology of ACL injurie …

31.08.2026journal-article

Journal of Pharmaceutical Science and Clinical Pharmacy

Formulasi dan Evaluasi Fisik Patch Mukoadhesif Ekstrak Biji Trembesi (Samanea saman (Jacq.) Merr.) Sebagai Kandidat Terapi Recurrent Aphthous Stomatitis

Suharti Suharti, Taufik Septiyan, Siti Julianingsih

Recurrent Aphthous Stomatitis (RAS) merupakan gangguan mukosa oral yang ditandai ulkus nyeri dan dapat mengganggu aktivitas sehari-hari. Penelitian ini bertujuan memformulasikan dan mengevaluasi sifat fisik patch mukoadhesif ekstrak biji trembesi (Samanea saman (Jacq.) Merr.) sebagai potensi kandidat sediaan untuk RAS. Penelitian eksperimental dilakukan menggunakan tiga formula (FI, FII, dan FIII) dengan variasi PVP, HPMC, dan etil selulosa. Ekstrak diperoleh melalui ekstraksi etanol 70%. Evaluasi meliputi organole …

31.08.2026journal-article

IIARD INTERNATIONAL JOURNAL OF ECONOMICS AND BUSINESS MANAGEMENT

Teachers Professional Development and Content Delivery in Public Senior Secondary Schools in Rivers State

Lily Adonye Hart

The study investigated teachers’ professional development and instructional delivery in public senior secondary schools in Rivers State. Three objectives were formulated and translated into corresponding research questions and hypotheses. The study adopted a correlational research design. The population for this study was 6,557 teachers in the 302 public senior secondary schools in Rivers State The sample for this study consisted of 984 teachers. The teachers were stratified into male and female groups. The sample …

31.08.2026journal-article

Journal of Market Access & Health Policy

Analysis of Factors Influencing Drug Prices Differently in Official Drug Pricing and Cost-Effectiveness Evaluation

Mariko Hara, Hiroshi Nakamura

Background: In Japan, official prices of pharmaceuticals have been determined by efficacy and safety. In 2019, Cost-Effectiveness Evaluation (CEE) was introduced to adjust these prices according to Incremental Cost-Effectiveness Ratios (ICERs). Objectives: To analyze the differences in the factors influencing drug price between the initial official drug pricing and subsequent price adjustments based on CEE. Methods: Twenty-three drugs evaluated in Japan between 2019 and May 2025 were descriptively analyzed using pu …

31.08.2026journal-article

Dermatology and Skin Science

POTUS’ Neck Rash: Impact on Public Skin Cancer Awareness

Nicolas Kluger

Media attention on a visible neck rash on US President Donald Trump, first noted 2 March 2026, at a White House ceremony, prompted dermatologists to speculate that the rash resulted from topical treatment for actinic keratosis (AK), though no official diagnosis was confirmed, as the White House physician only cited a “preventative skin treatment”. Google Trends and Wikipedia pageview data for related search terms (AK, imiquimod, fluorouracil, photodynamic therapy, rash, skin cancer) from January–April 2026 showed s …

31.08.2026journal-article

Frontiers in Public Health

Beyond the clinic: a community-embedded, multidomain framework for early detection of glaucoma

Akiko Hanyuda, Tetsuya Yamada, Satoru Tsuda, Noriko Himori, Toru Nakazawa

Glaucoma remains one of the leading causes of acquired irreversible blindness worldwide, with normal-tension glaucoma representing the dominant subtype in Japan and several East Asian populations. The insidious, asymptomatic progression of this condition, combined with the demonstrated inadequacy of intraocular pressure alone as a screening criterion, creates a critical gap between disease burden and case detection. Population-based epidemiological studies consistently reveal that the majority of individuals with g …

31.08.2026journal-article

Frontiers in Public Health

Research on the measurement of China's emergency management capabilities for public health emergencies and their driving factors

Li Yuan, Xiaocheng Gan, Kexin Zhang, Qianxi Zhang, Xie Yuan

Enhancing regional emergency response capabilities for public health emergencies poses a major challenge for China, which is undergoing rapid urbanization. Based on an analysis of the theoretical framework of emergency management for public health emergencies, this paper constructs an evaluation system comprising four dimensions: prevention and monitoring, emergency response, recovery and reconstruction, and emergency support. It employs the entropy weighting method to measure the emergency management levels of 285 …

31.08.2026journal-article

Journal of Surgical Oncology

Clinical Applications of 3D Specimen Scanning and Margin Mapping in Musculoskeletal Oncology: A 36 Patient Case Series

Riley S. Gilbertson, Sakshi Krishna, Joaquin Austerlitz, Andreja Radevic, Michael J. Colello, Alexander N. Perez, Reena Singh, Jennifer L. Halpern, Herbert S. Schwartz, Michael C. Topf, Joshua M. Lawrenz, Daniel J. Johnson

ABSTRACT Background Text‐based pathology reports inadequately communicate complex three‐dimensional (3D) relationships in musculoskeletal oncology, potentially contributing to errors in re‐resection and adjuvant treatment planning. While our prior 7‐case pilot study established technical feasibility, the scalability of this workflow and its utility as a platform for further innovation have not been demonstrated. Methods We conducted a prospective implementation study of 36 musculoskeletal oncology specimens at a te …

31.08.2026journal-article

Chulalongkorn Medical Journal

Beyond lipid-lowering: pleiotropic effects of statins in inflammation, coagulation, and cell proliferation – mechanisms and clinical implications

Kasidid Lawongsa, Yutthana Pansuwan, Supanut Kumjan

Statins are widely used lipid-lowering agents that significantly reduce cardiovascular morbidity and mortality through inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. Beyond their cholesterol-lowering properties, increasing evidence demonstrates that statins exert several pleiotropic effects independent of lipid reduction. These effects include anti-inflammatory, anti-thrombotic, and anti-proliferative actions mediated primarily through inhibition of the mevalonate pathway and downstream si …

31.08.2026journal-article

Clinical and Experimental Otorhinolaryngology

Responses of Nasal Polyp-Derived Macrophages to Inflammatory Cues and Potential Pathological Roles in Type 2 Chronic Rhinosinusitis With Nasal Polyps

Hyunkyung Cha, Ara Jo, Hee-Suk Lim, Kyoung Mi Eun, Jin-A Park, Seung-No Hong, Dae Woo Kim

Objectives. The role of highly plastic and heterogeneous macrophages in the pathogenesis of nasal polyps (NP) is not well understood. We aimed to investigate the distribution and responses of NP-derived macrophages to inflammatory cues according to endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP).Methods. The distribution of macrophage subsets was analyzed using NP bulk RNA sequencing data with CIBERSORTx program. The cytokines and chemokines produced by NP-derived macrophages following stimulation wi …

31.08.2026journal-article

Journal of Fetal Medicine

Effects of Prenatal Pulsed Electromagnetic Field and 27.12-Megahertz Radiofrequency Exposure on Fetal Development and Placental Stress Response in Rats

Gülüm Ceren Bozlu, Mekin Sezik, Rümeysa Taner, Halil Asci, Adem Milletsever, Ozlem Ozmen, Havva Serap Toru Ateser, Selçuk Cömlekci

Abstract Pulsed electromagnetic field (PEMF) and radiofrequency electromagnetic field (RF-EMF) stimulation promote neovascularization and angiogenesis and may have therapeutic potential for preventing or treating early-onset fetal growth restriction. We investigated the morphological and histopathological effects of PEMF and RF-EMF, administered separately or in combination, during early (gestational days 0–10) and late (days 10–20) pregnancy in a rat model. Thirty-two pregnant Wistar albino rats were randomly assi …

31.08.2026journal-article

Journal of Biophotonics

Autofluorescence Imaging and Methylene Blue‐Mediated Photodynamic Therapy for Early Detection and Management of Subclinical Actinic Cheilitis

Juliana Cristina Oliverio de Araújo, Og Fray Junior, Hermano Camelo Paiva, Alyne Simões Gonçalves, Martha Simões Ribeiro

ABSTRACT Objectives Optical autofluorescence imaging is a noninvasive adjunct for detecting potentially malignant oral disorders, such as actinic cheilitis (AC). This study evaluated its use for early detection and for monitoring tissue response following methylene blue‐mediated photodynamic therapy (MB‐PDT). Methods Lip autofluorescence was assessed using a handheld device (405 ± 20 nm). Areas with altered fluorescence underwent biopsy for confirmation. Patients with AC received five MB‐PDT sessions (660 nm, 100 m …

31.08.2026journal-article

International Journal Of Community Medicine And Public Health

Plantago ovata as a low-cost community-based dietary fibre intervention: a narrative review of evidence and public health applications

Mohammad Bilal, Rayyan Moin, Syed Sohaib Hashmi, Ali Jafar Abedi, Uzma Eram

Dietary fibre is an important but often underemphasized component of preventive nutrition and community health practice. Plantago ovata Forssk., commonly known as psyllium or Isabgol, is a soluble, gel-forming fibre widely used in South Asia and traditionally described in Unani dietotherapy as a demulcent and bulk-forming agent for digestive balance. A narrative review was conducted to synthesize traditional Unani descriptions and contemporary biomedical evidence on Plantago ovata, with emphasis on gastrointestinal …

31.08.2026journal-article

International Journal Of Community Medicine And Public Health

Feasibility of nationwide mapping of health facilities and community health workers in low-resource humanitarian contexts: lessons from Afghanistan

Boniface Francis Kalanda

Background: Reliable, up-to-date data on health facilities and community health workers (CHWs) are essential for effective health system planning, particularly in fragile and humanitarian settings where information gaps are common. However, large-scale mapping exercises are often considered impractical in such contexts. Methods: In 2025, a nationwide mapping of health posts and CHWs was conducted across all provinces of Afghanistan. A total of 1,291 community health supervisors were trained and deployed using a cas …

31.08.2026journal-article

BMC Public Health

Trends and disparities in stroke mortality with diabetes as a contributing cause among U.S. adults, 1999–2023: a uniform-definition national analysis of long-term decline and a post-2014, pandemic-era increase

Yan Cheng, Ji Li, Yunzhou Yang

Abstract Background Diabetes mellitus is a major contributor to cerebrovascular risk and stroke-related mortality. Although U.S. cardiovascular mortality declined for decades, national estimates for stroke mortality among people with diabetes have been inconsistent, partly because of differences in case definition and in the handling of the 2018 change in population race classification. Methods Using the CDC WONDER Multiple Cause of Death database, we studied U.S. adults aged ≥ 25 years (1999–2023) under a single, …

31.08.2026journal-article

Journal of Agricultural Policy and Transformation

<b>Junk Food Consumption and Child Health in Khyber Pakhtunkhwa, Pakistan: A Cross-Sectional Econometric Analysis with Agricultural and Food Policy Implications</b>

Samina Amin, Jamal Shah

Rising consumption of energy-dense, nutrient-poor junk food among Pakistani children is increasing public health risks and contributing to the burden of undernutrition and overnutrition. Evidence on behavioral and socioeconomic factors influencing junk food consumption in Pakistan remains limited, particularly its connection with agricultural and food-systems policy. This study examines associations between junk food consumption, media and advertising exposure, parental nutritional awareness, and caregiver-reported …

31.08.2026journal-article

Medical Journal of Western Black Sea

Evaluation of clinical-demographic characteristics and cardiovascular risk–related comorbidities in patients with early-stage mycosis fungoides

Pelin Ertop Doğan, Aleyna Demirel, Pelin Aladağ, Emel Hazinedar

Aim: Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma and usually follows a chronic, indolent course. Chronic inflammation involved in MF pathogenesis may contribute to the development of cardiovascular and metabolic comorbidities. This study aimed to evaluate the clinical and demographic characteristics and cardiovascular risk–related comorbidities in patients with early-stage MF.Material and Methods: This retrospective study included 62 patients diagnosed with early-stage MF (stages 1A, …

31.08.2026journal-article

Journal of Clinical Ultrasound

Could the Evaluation of Left Ventricular Filling Pressures by Mitral Doppler Predict the Respiratory or Hemodynamic Consequences of Volume Expansion?

Bénédicte Zerr, Nicolas Terzi, Nicholas Sedillot, Fabienne Prieur, Carole Schwebel, Vincent Peigne

ABSTRACT Background Many physicians assess left ventricular filling pressures (LVFP) with mitral Doppler before prescribing fluid infusion, in the hope of avoiding the occurrence of a deterioration of oxygenation. This work questions the merits of this practice. Patients and Methods Inclusion criteria were: adult patient receiving mechanical ventilation and vascular filling. Clinical and echocardiographic parameters were collected before and after volume expansion. Patients with increased LVFP (identified by at lea …

31.08.2026journal-article

International Journal Of Community Medicine And Public Health

Navigating the future of Indian nursing: nurse practitioner in midwifery as an innovation nexus in maternal healthcare

Hemavathi R., Soumya Krishna Gandavvagol, S. P. Subashini, Gandhimathi R., S. Tongpangkokla Ozukum, Prathiba S., Anubha Raina, Aparna Choudhury, Pooja Bakshi, Balamurugan E., Sowmiya V., Mohammed Umar

The Nurse Practitioner in Midwifery (NPM) programme represents a transformative initiative in India's maternal healthcare system, aiming to strengthen skilled birth attendance, improve the quality of maternity services, and address persistent shortages of qualified maternal healthcare professionals. This narrative review synthesizes current evidence on the evolution, educational framework, clinical roles, policy landscape, implementation challenges, and future prospects of the NPM programme. A comprehensive literat …

31.08.2026journal-article

International Journal Of Community Medicine And Public Health

A comparative study on health risk behaviours among adolescent high school students of urban and rural areas of Raichur district, Karnataka

Vignesh B., Sujatha N., Arshiya Taranum, Boramma G.

Background: Objectives of the study were to compare the prevalence and pattern of health risk behaviours among adolescent high school students in urban and rural areas of Raichur district, and to assess associated socio-demographic factors influencing these behaviours. Methods: A pre-tested WHO GSHS-based questionnaire was used in a school-based cross-sectional comparative study with 560 kids from August to October of 2025. Results: The sociodemographic features of the two groups were comparable. Students from urba …

31.08.2026journal-article

Journal of International Dental Sciences

Comparative Evaluation of Large Language Models as Virtual Orthodontic Patient Information Assistants

Alperen Erdoğan, Orhan Çiçek

Objective: The aim of this study was to evaluate the potential use of widely used large language models (LLMs) in patient education by comparing their responses to orthodontic patient questions in terms of accuracy, comprehensiveness, and readability.Methods: This study evaluated the performance of Claude Sonnet 4.6, ChatGPT 5.5 and Gemini 3.5 Pro in providing orthodontic patient information.Ten frequently asked questions by orthodontic patients were posed to each model in independent sessions using the same wordin …

31.08.2026journal-article

Nursing and Health Sciences Journal (NHSJ)

Comparative diagnostic accuracy of clinical screening instruments for diabetic peripheral neuropathy against vibration perception threshold: A study in Indonesia

Nunung Khairun Nissa Oper, Heri Kristianto, Laily Yuliatun, Rulli Rosandi

Diabetic peripheral neuropathy (DPN) is a major precursor of foot ulceration and amputation; however, validated low-cost screening tools remain limited in Southeast Asian populations. This study evaluated and compared the diagnostic accuracy of the MNSI-A, MNSI-B, DNS, and DNE against biothesiometer-defined DPN in Indonesian adults with type 2 diabetes. A cross-sectional diagnostic accuracy study recruited 140 consecutive patients with type 2 diabetes at Lavalette Hospital in Malang between August and September 202 …